• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Clinical events leading to the progression of heart failure: insights
Clinical events leading to the progression of heart failure: insights

... for other diagnoses in Table 1) are common precipitating events for heart failure exacerbations. These diagnostic codes were defined as ‘potential triggering events’. When these diagnoses were coded together with heart failure then it was assumed that the ‘potential triggering events’ had precipitat ...
Why Do We Have Purkinje Fibers Deep in Our Heart?
Why Do We Have Purkinje Fibers Deep in Our Heart?

... that these preferential conduction pathways, the best example of which is the interatrial bundle of Bachmann (Sedmera et al. 2006) can be explained by tissue geometry (pectinate muscles), in agreement with previous experimental data (Komuro et al. 1986), but are open to a marker that would distingui ...
Recurrent ventricular arrhythmias and myocardial infarctions
Recurrent ventricular arrhythmias and myocardial infarctions

... heart. Therefore, a single chamber ICD implantation was performed for secondary prevention. Our case shows that cocaine use can be associated with severe life-threatening arrythmias with or without myocardial infarction caused by coronary vasospasm. There are no extensive specified reports on ICD im ...
PDF - Circulation: Arrhythmia and Electrophysiology
PDF - Circulation: Arrhythmia and Electrophysiology

... terminated tachycardia, followed by injection of 1 to 3 mL of absolute ethanol, as previously described.17 After ablation, programmed right ventricular stimulation was performed with up to 3 extrastimuli and burst pacing and during administration of isoproterenol in selected cases. The acute success ...
Phys Chapter 9 [4-20
Phys Chapter 9 [4-20

... Normally, potentials are not conducted from the atrial syncytium to the ventricular directly through the fibrous tissue o Instead, they’re conducted through the specialized conductive system called the A-V bundle The separation of the heart muscle into 2 different syncytiums lets the atria contract ...
11 Hypertension Disease characteristics Clinical features
11 Hypertension Disease characteristics Clinical features

... the thick ascending limb of the loop of Henle. It should be noted that, with bendroflumethiazide, the most widely used agent, there is no benefit from increasing the dose above the optimum of 2.5 mg, because there is little additional antihypertensive effect and side effects are substantially increa ...
Sudden Cardiac Death in Young Athletes: A
Sudden Cardiac Death in Young Athletes: A

... the main debate is on the screening protocol (7). In this respect, the American Heart Association recommends 14 elements cardiac screening based on medical history and physical examination (8, 9, 10); these elements are outlined in table 2. This recommendation is adopted also by the American College ...
Stroke prevention in atrial fibrillation (AF) is an important goal of
Stroke prevention in atrial fibrillation (AF) is an important goal of

... the procedural risk of device implantation, the net health outcome will be improved. The evidence is sufficient to determine qualitatively that the technology results in a meaningful improvement in the net health outcome. ...
ECG Workbook - Lakeridge Health
ECG Workbook - Lakeridge Health

... transmission of the impulses throughout the heart in a coordinated manner, producing the rhythmic contraction associated with normal cardiac output. Impulses generated by the SA node travel along specialized tissue known as the conduction pathways. The impulse travels to the AV node where it is dela ...
Congenital heart surgery: what we do to our patients
Congenital heart surgery: what we do to our patients

... In cyanosed children with insufficient pulmonary blood flow, a shunt is formed from the systemic to the pulmonary circulation, to provide more pulmonary blood flow. This is usually in situations of obstructed right ventricular outflow, for example in tetralogy of Fallot, or pulmonary atresia. The co ...
Pulse PPT
Pulse PPT

... – Pulse deficit – heart condition in which heart is weak and does not pump enough to blood to produce a pulse or heart beats too fast and there is not enough time for the heart to fill with blood • The heart does not produce a pulse during each beat • Apical pulse rate is higher than the pulse rate ...
Heart Failure What is Heart Failure?
Heart Failure What is Heart Failure?

... • The heart looses it’s ability to relax because it becomes stiff • Heart cannot fill properly between each beat and less blood in means less blood out. ...
BUKOVINІАN STATE MEDICAL UNIVERSITY
BUKOVINІАN STATE MEDICAL UNIVERSITY

... V4 are often referred to as the anterior leads, and V5 and V6 join I and AVL as left lateral leads. The Normal 12-Lead ECG The P Wave Atrial depolarization begins at the sinus node, high up in the right atrium. The right atrium depolarizes first, then the e left atrium depolarizes. The vector of cur ...
Left Ventricular Assist Device as Destination Therapy
Left Ventricular Assist Device as Destination Therapy

... because their outcomes are frequently worse than those patients who have “straightforward” advanced HF. Given the young age of many patients with adult congenital heart disease, it is especially important to find options to prolong their lives with mechanical circulatory support. The data on LVADs i ...
Glucagon in Congestive Heart Failure
Glucagon in Congestive Heart Failure

... Glucagon in continuous infusion would be expected to be of maximum benefit in acute congestive heart failure. From the data presented, its use does not seem justified in chronic C H F unless all other therapeutic maneuvers are exhausted. Serum glucose and potassium must be determined frequently. Cau ...
Executive summary of the guidelines on the diagnosis and treatment
Executive summary of the guidelines on the diagnosis and treatment

... Guidelines and Expert Consensus documents aim to present all the relevant evidence on a particular issue in order to help physicians to weigh the benefits and risks of a particular diagnostic or therapeutic procedure. They should be helpful in everyday clinical decision-making. A great number of Guid ...
CIMC Medical-Surgical Nursing I Practical Nursing
CIMC Medical-Surgical Nursing I Practical Nursing

... function affects the patient and the way the LPN delivers patient care. The nurse must be able to discuss and demonstrate safe, effective care for the cardiac patient. Additionally, the nurse must have the knowledge to assist with and modify appropriate nursing care, support, and teaching needed for ...
Technical Aspects of Coronary Sinus Catheterization Based on the
Technical Aspects of Coronary Sinus Catheterization Based on the

... diseases in the occidental world1. Although the therapeutical stock developed for the disease management in the last years, there are many refractory to the treatment patients. In a context of relative disappointment regarding to the clinical and surgical therapeutic modalities, the cardiac pacemake ...
Understanding the Electrocardiogram
Understanding the Electrocardiogram

... Review of the conduction system EKG: Electrodes and Leads EKG: Waveforms and Intervals Determining heart rate Determining Rhythm Determining QRS Axis To be continued ...
File
File

... 79- which one of the following statements is true about heart sounds a- 1st heart sound is heard during the T wave b- 2nd heart sound is heard during the S wave c- both heart sounds occur during the isovolumic contraction d- 2nd heat sound is heard during the isovolumic relaxation e- these sounds ar ...
Moderate severity heart failure does not involve a - AJP
Moderate severity heart failure does not involve a - AJP

... FAO enzymes [MCAD and carnitine palmitoyl transferase I (CPT-I)] accompanied by enhanced glucose oxidation was also reported in dogs with advanced end-stage HF induced by rapid ventricular pacing (26). Thus severe end-stage HF appears to be characterized by a switch to a more fetal metabolic phenoty ...
diagnostic efficiency of serum creatine kinase and troponin i in
diagnostic efficiency of serum creatine kinase and troponin i in

... VLDL-C and IDL-C. Since most of cholesterol in the plasma is carried by LDL, an increase in LDL level directly may lead to an increase in TC levels as well (20). Elevated plasma LDL level may be due to over production or decrease its clearance as a result of modifying and blocking of LDLreceptors lo ...
Left Atrial Volume Index as a Clinical Marker for Atrial Fibrillation
Left Atrial Volume Index as a Clinical Marker for Atrial Fibrillation

... muscle in pathological studies. It was demonstrated that there is clear evidence in the human atrial muscle of age-related electrical uncoupling of the side-to-side connections between bundles, related to the proliferation of extensive collagenous tissue septa in intracellular spaces [13,14]. These ...
CHF - rEMERGs
CHF - rEMERGs

... (aka 1 whole cardiology fellowship in an hour) ...
Heart Rate Variability in Time Domain after Acute Myocardial Infarction
Heart Rate Variability in Time Domain after Acute Myocardial Infarction

... exhibiting different conduction velocities and refractory periods. In case of unidircctional block, the entering impulse is conducted antegradely through one pathway, but blocked in thc second pathway. From the distal connection the impulse is conducted retrogradely throu&, the second limb. If the i ...
< 1 ... 216 217 218 219 220 221 222 223 224 ... 680 >

Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report