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Pericardial Effusions – Diagnosis and Treatment
Pericardial Effusions – Diagnosis and Treatment

... the clinical presentation. Signs of systemic congestion generally develop at venous pressures that are lower than those that cause pulmonary congestion. Most veterinary patients with PE are therefore presented for evaluation of signs such as ascites. Pulmonary edema is uncommon in the setting of tam ...
Tracking the Right Ventricle - JACC: Cardiovascular Imaging
Tracking the Right Ventricle - JACC: Cardiovascular Imaging

HCM_03 (Natural history)
HCM_03 (Natural history)

... A. In series published in 1980s, annual mortality of patients with HCM in referral center populations was 4 to 6% per year. However, lower annual mortality rates have been observed in more recent series from large unselected HCM patient populations (approximately 1% per year). In report from referra ...
Pediatric Heart Update - Le Bonheur Children`s Hospital
Pediatric Heart Update - Le Bonheur Children`s Hospital

... atria. In most cases, this opening closes around the time of birth. If the opening remains after birth, it can allow the blood to mix in the two upper chambers of the heart. Untreated it may increase the risk for stroke by allowing clots to cross from the right side of the heart to the left. It is n ...
Impaired Post Exercise Heart Rate Recovery in Anabolic Steroid Users ▼ 931
Impaired Post Exercise Heart Rate Recovery in Anabolic Steroid Users ▼ 931

... These findings favor the idea that both vagal and sympathetic cardiac controls during exercise are preserved in strengthtrained young athletes with AAS use. Likewise, no alteration in peak oxygen pulse was found in the present study, which suggests that systolic cardiac function is preserved in AASU ...
The ECG hypertrophy of the right atrium and the right ventricle, the
The ECG hypertrophy of the right atrium and the right ventricle, the

... detect the prevalence of this or any other blemish, and establish the degree of narrowing of the tricuspid orifice. ...
Manifestations Mimicking Acute Myocardial Infarction after
Manifestations Mimicking Acute Myocardial Infarction after

... dynamic change for days, followed by T-wave inversion and resolved in approximately 2-3 weeks6,16 associated with QTc prolongation.16 Abnormal Q-wave and reciprocal changes are rarely seen.16 Our case has similar initial manifestation as seen in Takotsubo cardiomyopathy, but the changes in cardiac e ...
Alteration of Systolic Time Intervals in Right Ventricular
Alteration of Systolic Time Intervals in Right Ventricular

... Medicine recorder. The pre-ejection period (PEP) was derived from simultaneous brachial arteriai pressure and ECG tracings recorded at 50 mm/see paper speed. PEP was defined as that interval from the onset of the QRS (lead II) to the onset of the upstroke of the brachial arterial pressure tracing. T ...
(TAPVC): Supracardiac - Children`s Heart Clinic
(TAPVC): Supracardiac - Children`s Heart Clinic

...  Supracardiac: The pulmonary veins drain to the right superior vena cava (SVC) through the left vertical vein and left innominate vein. This type accounts for 50% of TAPVC.  Infracardiac: The common pulmonary venous sinus drains to the portal vein, ductus venosus, hepatic vein or inferior vena cav ...
OMEGA-3 FATTY ACIDS AND - GOED Omega-3
OMEGA-3 FATTY ACIDS AND - GOED Omega-3

... result from cardiovascular disease (CVD), with more than 2,100 people dying from it each day.1 Although the treatment of CVD has improved markedly in the last decade, other factors such as hypertension, smoking, type 2 diabetes, physical inactivity and poor diet contribute substantially to an indivi ...
Status of Antiarrhythmic Drug Development for Atrial Fibrillation
Status of Antiarrhythmic Drug Development for Atrial Fibrillation

... vernakalant with amiodarone15 and flecainide,16 respectively, demonstrated that vernakalant had a statistically superior efficacy to placebo, but not to other antiarrhythmic drugs during pooled analysis. However, individual studies comparing vernakalant with amiodarone, flecainide and propafenone ha ...
endomyocardial fibrosis
endomyocardial fibrosis

... Hypereosinophilia produces the first phase of endomyocardial disease characterized by necrosis, intense myocarditis, and arteritis (i.e.Loffler ...
PDF - Circulation: Arrhythmia and Electrophysiology
PDF - Circulation: Arrhythmia and Electrophysiology

... improvement in clinical composite score (CCS) and reduction of left ventricular end systolic volume (LVESV) of ⬎15% after 6 months. Age, sex, cause of cardiomyopathy, myocardial infarction location, right ventricular function, mitral regurgitation, preimplantation QRS width, preimplantation PR inter ...
Review Article Ventricular Tachycardia in the Absence of Structural
Review Article Ventricular Tachycardia in the Absence of Structural

... tachycardia (LVOT VT). The S wave in LI and R-wave transition in V1 suggest LVOT VT. In addition, an R:S amplitude ratio of 30% and an R:QRS duration ratio of 50% are seen. Presence of an S wave in leads V5 and V6 suggests an infravalvular origin of the tachycardia. Exercise stress testing is used f ...
Présentation PowerPoint - Clinical Trial Results
Présentation PowerPoint - Clinical Trial Results

... For internal u events (defined as cardiac death, all MI, TVR); MI=myocardial infarction; n/a=not applicable (events defined as regardless of relationship to stent); QWMI=Q-wave MI; NQWMI=non-Q-wave MI; TVR=target vessel revascularization. Time-to-event rates. ...
Benefit Definition: Unstable Angina/Non ST
Benefit Definition: Unstable Angina/Non ST

... (CAD), 35% have 2-vessel CAD, and 50% have 3-vessel CAD. The incidence of left main disease is roughly 510%. The rate of thrombus detected at coronary angiography varies widely, ranging from less than 10% among those with chest pain in the previous month to more than 50% among those with rest angina ...
Name of presentation
Name of presentation

... • The fastest functioning pacemaker in the heart takes over, by default • The closer to the AV node, the more the escape beat will resemble normal QRS • The closer to the ventricle, the more wide and bizarre the QRS will appear • Escape rhythm – pacemaker other than SA node takes over, because SA no ...
macrowave t alternans or macroscopic alternation in a
macrowave t alternans or macroscopic alternation in a

... positive end (+) to the epicardium, gaining positive charges in the direction of the endocardium, where the origin (-) of the vector is located. In adults, T vector of repolarization is relatively parallel to the QRS vector of depolarization. Experimental studies have shown that the alternation is d ...
Isolated Double-Chambered Right Ventricle in a Young Adult
Isolated Double-Chambered Right Ventricle in a Young Adult

... The period for surgical repair usually depends on the associated cardiac anomalies. In the absence of a significant coexisting defect, observation is possible as long as the intracavitary systolic gradient is not greater than 40 mmHg and the obstruction is not progressive.10) The long term prognosis ...
October 2016 Heartbeat: Rehabilitation of Digoxin
October 2016 Heartbeat: Rehabilitation of Digoxin

... National Institutes of Health–sponsored DIG (Digitalis Investigation Group) trials.5 All of these studies provide evidence for the safety and efficacy of digoxin. The landmark DIG trial reduced the risk of hospitalization due to HF by 28% during 37 months (average) of follow-up without a significant ...
Exercise training increases oxygen uptake efficiency slope in
Exercise training increases oxygen uptake efficiency slope in

... the arterial carbon dioxide set point in CHF patients does not differ from normal [20]. Metabolic acidosis in CHF patients, however, occurs at lower work loads than in healthy persons as a consequence of reduced muscle perfusion and structural muscular changes [21]. This causes increased ventilation ...
E lectrocardiographic criteria for vagotonia—validation with
E lectrocardiographic criteria for vagotonia—validation with

... Seven subjects had a J-point elevation with at least 0.1 mV of amplitude, accompanied by a ST-segment elevation with superior concavity, in at least 2 leads. This pattern completely disappeared in six of the seven subjects (83%), having remained in only one lead of the seventh subject, who presented ...
Principles of Cardiac Pacing
Principles of Cardiac Pacing

... the patient’s intrinsic electrical activity (mV) – Insufficient myocardial voltage – Dislodged, loose, fibrotic, or fractured electrode – Electrolyte abnormalities – Low battery voltage ...
Cardiovascular Anatomy and Physiology
Cardiovascular Anatomy and Physiology

... The cardiac output is the volume of blood that is ejected from the left ventricle into the aorta over a given time period (L/min). At rest cardiac output is 4-8 L/min in an healthy adult. This can rise up to 25 litres/min during severe exercise. ...
at different heart rates - IFM
at different heart rates - IFM

... well-known Frank–Starling mechanism. Although this 58.3±3.5·beats·min–1 (N=10) to 0.07±0.05·kPa after mechanism is well understood from heart perfusion injection of zatebradine (4·mg·kg–1). The operation of the studies, less is known about how this mechanism operates so-called time-dependent autoreg ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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