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Randomized controlled trial of home-based
Randomized controlled trial of home-based

... There is evidence that multiple benefits can be obtained through exercise training that leads to increases in peak oxygen consumption (VI O2). It is unclear whether significant improvements can also be achieved through unsupervised low-budget home-based training regimes, especially in terms of cardi ...
The Art and Science of Diagnosing and Treating Lung and Heart
The Art and Science of Diagnosing and Treating Lung and Heart

... Patients with chronic liver disease are at risk of extrahepatic complications related to cirrhosis and portal hypertension, as well as organ-specific complications of certain liver diseases. These complications can compromise quality of life, while also increasing morbidity and mortality before and a ...
Fiber-Optic Stethoscope: A Cardiac Monitoring and Gating System
Fiber-Optic Stethoscope: A Cardiac Monitoring and Gating System

... Several strategies can be employed to improve the quality of the ECG during MRI, including the use of complex signal processing techniques (6,7) and high-resistance or even fiber-optic leads to electrically isolate the ECG circuit (8). Despite these techniques, the ECG, being an inherently electrica ...
The thick left ventricular wall of the giraffe heart normalises wall
The thick left ventricular wall of the giraffe heart normalises wall

... RESEARCH ARTICLE ...
Restraint associated profound lactic acidosis in a cocaine
Restraint associated profound lactic acidosis in a cocaine

... production, mechanical ventilation to increase minute ventilation, and fluid administration to improve tissue perfusion to optimize metabolism of accumulated lactate has been associated with markedly improved patient survival (2). Compensatory hyperventilation in response to metabolic acidosis may b ...
Assessment of left ventricular diastolic function in bronchial asthma
Assessment of left ventricular diastolic function in bronchial asthma

... Bronchial asthma (BA) has a wide clinical spectrum ranging from a mild intermittent disease to one that is severe, persistent, difficult to treat, and in some cases, fatal1,2,3. Cardiovascular affection in BA can be related directly to the acute severe asthma, which profoundly alters cardiovascular ...
WD Weaver, CE Fahrenbruch, DD Johnson, AP
WD Weaver, CE Fahrenbruch, DD Johnson, AP

... Resuscitation (64% vs. 50%, p<0.005) but not survival rates (24% vs. 20%) were higher during the prior 2-year period in which initial adjunctive drug treatment for persistent ventricular fibrillation primarily consisted of a continuous infusion of sodium bicarbonate. The negative effect of lidocaine ...
Time From the Beginning of the Right Ventricle Isovolumetric
Time From the Beginning of the Right Ventricle Isovolumetric

... diagnosis of PH. This research was conducted from February of 2013 until March of 2014 at the Rajaie cardiovascular medical and research center, a tertiary care center for cardiovascular patients in Tehran, Iran. In this period, 60 patients who were candidates for RHC were considered to be eligible ...
Free Sample
Free Sample

... blood in the heart during diastole, the more forceful the cardiac contraction, and the more blood the ventricle will pump (stroke volume). This is important so that the heart can adjust its pumping capacity in ...
Exercise for Patients with Coronary Artery Disease
Exercise for Patients with Coronary Artery Disease

... including left ventricular dysfunction, myocardial ischemia, or cardiac arrhythmias. Abnormalities identified may then be managed medically or surgically prior to beginning the exercise program. Patients identified as high risk for cardiovascular complications during exercise include patients with u ...
Cardiac defects in chromosomally normal fetuses with abnormal
Cardiac defects in chromosomally normal fetuses with abnormal

... heart defects, post-tachycardia cardiomyopathy and endstage fetal hypoxia12–14 or increased right ventricular afterload15. It is well recognized, however, that, in most forms of major structural heart defect, fetal well-being is not markedly affected and overt evidence of cardiac dysfunction is not ...
Electrocardiographic Early Repolarization A Scientific Statement
Electrocardiographic Early Repolarization A Scientific Statement

... he early repolarization (ER) pattern (ERP), initially described as elevation of the ST segment of ≥1 leads on the 12-lead ECG, has long been considered a benign phenomenon. However, more recent studies have demonstrated positive, negative, and neutral associations between an ERP and various end poin ...
Scholars Journal of Medical Case Reports Pulmonary Atresia with
Scholars Journal of Medical Case Reports Pulmonary Atresia with

... Tetralogy of Fallot (TOF) with pulmonary atresia (PAVSD), and is estimated to represent 5% to 10% of tetralogy of Fallot patients[2]and also accounts to 2 – 3 % of all the congenital cardiac malformations [1,3-5]. It’s a duct dependent lesion of neonate with Survival in the post natal period dependi ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... have been described.7,8 These has shown that left ventricle and interventricular septum involvement has a poor prognosis. Clinically,it has been shown also that patients with left ventricular hypertrophy(LVH) have significantly more premature contractions than normal individuals or those with hypert ...
Genesis of electrocardiography []
Genesis of electrocardiography []

... At every given moment, the electrical status of each cardiac cell can be characterized by an elementary vector. All these elementary vectors can be moved so that their origins are all brought into a single common point – the electrical center of the heart. The sum of all elementary vectors arising i ...
Pharmacology and the Nursing Process, 4th ed. Lilley/Harrington
Pharmacology and the Nursing Process, 4th ed. Lilley/Harrington

... Used in the intensive care setting as a final effort to treat severe, life-threatening heart failure, often in combination with several other cardiostimulatory medications ...
-Tachycardia: > --is the> patient hemodynamically stable
-Tachycardia: > --is the> patient hemodynamically stable

... In the healthy adult with a “normal” EKG the R wave will progress as it moves from lead V4 to V6. In this case, progression means that the wave increases in size and grows taller. On the other hand, “poor progression” is when the R wave does not increase in size at all or increases very slowly. Poor ...
Syncope - A Clinical Point of View - The Association of Physicians of
Syncope - A Clinical Point of View - The Association of Physicians of

... 4. History of critical coronary artery disease, old myocardial infarction, or left ventricular failure- Ventricular tachycardia. 5. History suggestive of acute MI- Ventricular tachyarrhythmia, onset of high degree AV block, transient severe sinus bradycardia. 6. Startle response- ventricular tachyca ...
CMS Stress Echo
CMS Stress Echo

... evaluated. Complications of acute infarction (e.g., mural thrombi, papillary muscle dysfunction and rupture, septal defects, true or false aneurysm and myocardial rupture) can be diagnosed and their contribution to the overall clinical status placed in perspective. Following an initial TTE in the se ...
Inter-ventricular septum: New observations on the structure and
Inter-ventricular septum: New observations on the structure and

... contrast with the prevailing understanding of ventricular function established over centuries, an ongoing debate appeared in the international literature from supporters on one side and from strong critics on the other [2-6,917,21,22,25-29,46,47,49-51,65,66,80,81]. Within the last few years, in addi ...
Pacemaker Development in Embryonic Rat Heart Cultured
Pacemaker Development in Embryonic Rat Heart Cultured

... A difference in the beating rate of atrial and ventricular tissue was expected based on the experiments of DeHaan (4) and LeDourain et al. (32) in which precardiac mesoderm explants destined to be atrium or ventricle were cultured separately. The atrial anlage beat more rapidly than the ventricular ...
Genetic influence on electrocardiogram time intervals - AJP
Genetic influence on electrocardiogram time intervals - AJP

... diagnose and predict some cardiac arrhythmias and other cardiac diseases. Forty years ago, Goldbarg et al. (18) noted ECG differences between anesthetized mice of two strains. Since then, ECG characteristics of different mouse strains have been reported, but the inconsistent techniques used make it ...
Cardiologic examinations in ferrets with and - diss.fu
Cardiologic examinations in ferrets with and - diss.fu

... stocky legs, and five toes per foot, elongated brain case, and a short rostrum. The domestic ferret, Mustela putorius furo, has a long body, with short muscular legs and a long tail. The adult’s average body length of 44 to 46 centimeter (cm) from the nose to the tip of the tail was reported by Fox ...
Does this patient have CHF - Division of General Internal Medicine
Does this patient have CHF - Division of General Internal Medicine

... BNP) since clinicians rely on these basic investigations in conjunction with their history and physical examination in bedside decision making.22,36 There are currently multiple BNP assays approved by the US Food and Drug Administration for clinical use. To date, the largest published randomized cli ...
Time From the Beginning of the Right Ventricle Isovolumetric
Time From the Beginning of the Right Ventricle Isovolumetric

... diagnosis of PH. This research was conducted from February of 2013 until March of 2014 at the Rajaie cardiovascular medical and research center, a tertiary care center for cardiovascular patients in Tehran, Iran. In this period, 60 patients who were candidates for RHC were considered to be eligible ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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