• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Neural and Neurosecretory Control of the Decapod Crustacean
Neural and Neurosecretory Control of the Decapod Crustacean

... time ago when it was termed the cor fron- were made either from the intact or isotale (L. frontal heart) (Bouvier, 1891; lated perfused animal, as specified in the Baumann, 1917; and Maynard, 1960, for text. Recording from the intact animal was review). However, only a brief description done by inse ...
Canadian Cardiovascular Society Consensus Conference
Canadian Cardiovascular Society Consensus Conference

... failure – 2008 update: Best practices for the transition of care of heart failure patients, and the recognition, investigation and treatment of cardiomyopathies. Can J Cardiol 2008;24(1):21-40. Heart failure is a clinical syndrome that normally requires health care to be provided by both specialists ...
distribution of edema
distribution of edema

... activation of the RAAS and renal sympathetic nerves and to release of A VP, endothelin, and other sodium and water-retaining mechanisms. In later stages, particularly when there is severe hypoalbuminemia, peripheral edema may develop. ...
Effects of Increasing Left Ventricular Filling Pressure in Patients with
Effects of Increasing Left Ventricular Filling Pressure in Patients with

... The calculated value agreed with the planimetered value within 2.9 ±2.9%o (17). 'The factor 0.90 was obtained experimentally in 11 instances on 10 patients with a recorded aortic pressure by relating the plainimetrically determined mean systolic pressure to the peak aortic systolic pressure. The fac ...
Omega-3 Fatty Acids, Acute Coronary Syndrome, and Sudden Death
Omega-3 Fatty Acids, Acute Coronary Syndrome, and Sudden Death

... unstable angina) remains less clear. Such a benefit was observed in JELIS [12••] but not in DART [7] or GISSI [10]. However, the cumulative rate of major coronary events (the primary end point, largely nonfatal events) in the 5-year period was much lower in JELIS than in comparable studies in Wester ...
Force-frequency Relations in Hypertrophic Heart Muscle
Force-frequency Relations in Hypertrophic Heart Muscle

... computer simulation d a t a . Increasing parameter Sre in each case only lowered the slope of the static force-frequency response (see Table 2, rows 3, 5, 7). It can be concluded from the comparison of experimental and simulation d a t a t h a t , from the above hypotheses concerning mechanisms of m ...
Single-Beat Noninvasive Imaging of Cardiac
Single-Beat Noninvasive Imaging of Cardiac

... source points to the simulated potentials at the electrode locations (9). A Wilson terminal defined the reference for measured and computed unipolar signals (10). For inverse computation of the ventricular activation sequence, the target beats were selected with an automated signal processing algori ...
Diovan 160 mg film-coated tablet ENG
Diovan 160 mg film-coated tablet ENG

... increased plasma levels of Ang II following AT1 receptor blockade with valsartan may stimulate the unblocked AT2 receptor, which appears to counterbalance the effect of the AT1 receptor. Valsartan does not exhibit any partial agonist activity at the AT1 receptor and has much (about 20,000 fold) grea ...
The Heart and Cardiac Output
The Heart and Cardiac Output

Paroxysmal supraventricular tachycardia: physiopathology and
Paroxysmal supraventricular tachycardia: physiopathology and

... has an excellent outcome. Vagal manoeuvres are effective in patients with atrioventricular reentrant tachycardia. Adenosine is the drug of choice at all ages for tachycardias involving the atrioventricular node. Its key advantage is its short half life and minimum or no negative inotropic effects. V ...
Diagnosis and management of chronic heart failure
Diagnosis and management of chronic heart failure

... mild (NYHA Class II) symptoms, despite receiving standard therapies with ACEIs and beta-blockers. Use diuretics, digoxin and nitrates to manage symptoms as indicated in people already receiving ACEIs and beta-blockers. Fish oils should be considered as a second-line treatment for people with CHF who ...
S 2
S 2

A letter from the CEO of Heart Rhythm Society, James H. Youngblood
A letter from the CEO of Heart Rhythm Society, James H. Youngblood

... provide guidance to help providers make informed clinical decisions and ensure optimal patient care. Evidence-based medicine is the foundation of health policy efforts. ...
A summary perspective on the clinical
A summary perspective on the clinical

... cardiac and digestive forms of disease the intrinsic innervation of heart is commonly more markedly damaged by inflammatory and degenerative alterations and decrease in the number of cardiac ganglion cells and neurons was undoubtedly showed 2 6 8 20 28 32 37 38 46 55. Based on this pathological subs ...
Standard Operating Procedures
Standard Operating Procedures

... (V5 ) Horizontally even with V4, but in the anterior axillary line. (The anterior axillary line is the imaginary line that runs down from the point midway between the middle of the clavicle and the lateral end of the clavicle; the lateral end of the collarbone is the end closer to the arm.) (V6 ) Ho ...
CARDIAC PHARMACOLOGY OF THE CLADOCERAN, DAPHNIA
CARDIAC PHARMACOLOGY OF THE CLADOCERAN, DAPHNIA

... After replacement of the atropine by water the heart beat did not return to its normal rate but remained low for many hours, after which the animals died. Experiments on the antagonism of acetylcholine by atropine, such as was observed by Obreshkove, were thus impossible to perform. These results do ...
Imaging Methods for Morphological and Functional Phenotyping of
Imaging Methods for Morphological and Functional Phenotyping of

... Cardiac Micro-CT Micro-CT has been used to image the isolated, fixed rodent heart with 25 micron spatial resolution (Jorgensen et al., 1998) resulting in a 3D reconstruction of the heart with superb anatomical detail. However, in vivo cardiac micro-CT in mice was considered to be “illusive” (Lazebni ...
Cardiogenic Shock Due to Dynamic Left Ventricular Outflow Tract
Cardiogenic Shock Due to Dynamic Left Ventricular Outflow Tract

... of hypertrophy of the basal septum, and b) a hyperdynamic left ventricular situation. This tends to occur most frequently in older patients with a history of hypertension and left ventricular hypertrophy, although hypertension is not an indispensable requirement. Another clinical group is constitute ...
the Cardiac Surgery Family Handbook
the Cardiac Surgery Family Handbook

... Family Camp Weekend is designed specifically for families of children affected with heart disease. The weekend is full of fun family activities, informational sessions for parents and sharing with other families who have had similar experiences. ...
INDICATION OF COA STENTING IN INFANTS & CHILDREN
INDICATION OF COA STENTING IN INFANTS & CHILDREN

... • Participants were randomly assigned to BA or surgery with equal probability. • For subjects randomized to BA, the balloon diameter was selected to match the diameter of the uninvolved aorta proximal to the coarctation. ...
Recommendations for participation in competitive and leisure sports
Recommendations for participation in competitive and leisure sports

... Background Physical activity is important for patients with congenital heart disease. The aim of this paper is to provide a consensus document for participation in competitive or leisure sport activity in children and adults with congenital heart disease. Methods The recommendations are based on exp ...
Favorable Results in Patients with Small Size CarboMedics Heart
Favorable Results in Patients with Small Size CarboMedics Heart

... the left ventricular overload and improvement of the clinical symptoms as well as cardiac function were comparable to those of patients with larger valves. Valve function measured by echocardiography did not show significant correlation to late outcome. Good results can be expected even in the prese ...
Mahaim fibre
Mahaim fibre

... study. Mahaim fibre mapping methods like (i) Mahaim potential (M), (ii) shortest atrial stimulus-to-preexcitation (STP), and (iii) mechanical trauma induced loss of conduction were studied. Accessory pathway mapping was performed by M potential in 10 patients (67%), shortest atrial STP in 3 patients ...
Historical review of clinical electrocardiographic lead systems and
Historical review of clinical electrocardiographic lead systems and

... has also been presented over the years. Linder and Katz 6 in a series of experiments involving the insertion of insulating materials between the heart and the surrounding tissues demonstrated that the posterior muscle mass is the best electrical conductor, followed by the diaphragm and its adjacent ...
Lipomatous Hypertrophy of the Interatrial Septum Accompanied By
Lipomatous Hypertrophy of the Interatrial Septum Accompanied By

... It is supported by studies that LHIS can induce arrhythmia and LHIS related p wave alterations, atrial arrhythmias and sudden cardiac deaths.8,10-13 The characteristic appearance of top and/or bottom part of interatrial septum which seems to be separated from foramen ovale is called as ‘dumbbell sha ...
< 1 ... 186 187 188 189 190 191 192 193 194 ... 680 >

Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report