Cardiac Responses to Increased Afterload
... pressure-volume relationship. In isovolumetric contractions (i.e., with no change in volume), the peak pressure generated by the ventricle varies with the enddiastolic volume; this is a manifestation of the wellknown Frank-Starling mechanism, or the normal ventricle, it has been found that, under th ...
... pressure-volume relationship. In isovolumetric contractions (i.e., with no change in volume), the peak pressure generated by the ventricle varies with the enddiastolic volume; this is a manifestation of the wellknown Frank-Starling mechanism, or the normal ventricle, it has been found that, under th ...
Inhibition in the human heart
... bipolar pair and the proximal bipolar pair was used to record the local electrogram. In nine patients S I and S2 were initiated at the distal bipolar electrode pair but Sc was introduced at the proximal bipolar pair. For these patients the catheter was positioned so that late-diastolic pacing thresh ...
... bipolar pair and the proximal bipolar pair was used to record the local electrogram. In nine patients S I and S2 were initiated at the distal bipolar electrode pair but Sc was introduced at the proximal bipolar pair. For these patients the catheter was positioned so that late-diastolic pacing thresh ...
The Johns Hopkins Hospital
... Develop and demonstrate in-depth knowledge of the pathophysiology, clinical manifestations, diagnosis and management of cardiac diseases, as seen in a Coronary Care unit. Develop and demonstrate in-depth knowledge of the principles of diagnosis and management of essential hypertension; ischemic hear ...
... Develop and demonstrate in-depth knowledge of the pathophysiology, clinical manifestations, diagnosis and management of cardiac diseases, as seen in a Coronary Care unit. Develop and demonstrate in-depth knowledge of the principles of diagnosis and management of essential hypertension; ischemic hear ...
Valsartan, Captopril, or Both in Myocardial Infarction
... women 18 years of age or older who had had acute myocardial infarction (between 0.5 and 10 days previously) that was complicated by clinical or radiologic signs of heart failure, evidence of left ventricular systolic dysfunction (an ejection fraction 0.35 on echocardiography or contrast angiography ...
... women 18 years of age or older who had had acute myocardial infarction (between 0.5 and 10 days previously) that was complicated by clinical or radiologic signs of heart failure, evidence of left ventricular systolic dysfunction (an ejection fraction 0.35 on echocardiography or contrast angiography ...
MITRAL VALVE DISEASE IN CHILDREN AND ADULTS
... important aspect of contemporary VHD is the growing number of previously treated patients who are presented with further problems. In contrast, rheumatic valve disease remains a major public health problem in developed countries, where it affects mostly the younger population. When compared with oth ...
... important aspect of contemporary VHD is the growing number of previously treated patients who are presented with further problems. In contrast, rheumatic valve disease remains a major public health problem in developed countries, where it affects mostly the younger population. When compared with oth ...
Can prolonged exercise-induced myocardial ischaemia be
... Aims To evaluate the innocuousness of intense and prolonged exercise training above the threshold for myocardial ischaemia (1 mm ST-segment depression). Methods and results Twenty-two patients with ischaemic heart disease (IHD) were randomized to exercise training either at a target intensity that i ...
... Aims To evaluate the innocuousness of intense and prolonged exercise training above the threshold for myocardial ischaemia (1 mm ST-segment depression). Methods and results Twenty-two patients with ischaemic heart disease (IHD) were randomized to exercise training either at a target intensity that i ...
Preoperative cardiac management of the patient evidence-based approach
... valve area,1 cm2 or ,0.6 cm2 m22) carries the highest perioperative cardiovascular morbidity and mortality in non-cardiac surgery. The key factors in the preoperative decision-making are severity of stenosis and clinical condition. The preoperative management of patients with asymptomatic but severe ...
... valve area,1 cm2 or ,0.6 cm2 m22) carries the highest perioperative cardiovascular morbidity and mortality in non-cardiac surgery. The key factors in the preoperative decision-making are severity of stenosis and clinical condition. The preoperative management of patients with asymptomatic but severe ...
Print this article - Medical Journal of Indonesia
... Intracardiac thrombus, for example left atrial and left ventricular thrombus, is associated with several conditions especially low flow states such as in mitral stenosis, atrial fibrillation, and ischemic heart disease.1–4 Increased morbidity and mortality are associated with its embolization.3–6 Th ...
... Intracardiac thrombus, for example left atrial and left ventricular thrombus, is associated with several conditions especially low flow states such as in mitral stenosis, atrial fibrillation, and ischemic heart disease.1–4 Increased morbidity and mortality are associated with its embolization.3–6 Th ...
Ventricular fibrillation: evolution of the multiple
... Spiral breakup develops only if the medium is su¯ ciently large (Courtemanche & Winfree 1991; Karma 1994). If this critical condition is not met, the following two scenarios are possible. The spiral does not break up and remains stable for an in nitely long time. Alternatively, the spiral breaks up ...
... Spiral breakup develops only if the medium is su¯ ciently large (Courtemanche & Winfree 1991; Karma 1994). If this critical condition is not met, the following two scenarios are possible. The spiral does not break up and remains stable for an in nitely long time. Alternatively, the spiral breaks up ...
Indian Pacing and Electrophysiology Journal - Antzelevitch
... been recognized for a long time and the effect of single chamber right ventricular (RV) apical pacing (VVI) on left ventricular (LV) functions has been studied previously, yet there remain some unexplored areas such as the chronology of events to occur.1-8 Majority of studies have looked into LV dys ...
... been recognized for a long time and the effect of single chamber right ventricular (RV) apical pacing (VVI) on left ventricular (LV) functions has been studied previously, yet there remain some unexplored areas such as the chronology of events to occur.1-8 Majority of studies have looked into LV dys ...
BUKOVINІАN STATE MEDICAL UNIVERSITY
... transplant may be considered. Transplants increase life expectancy in persons with advanced heart failure who might otherwise be expected to live less than six months. Currently, 80 to 90 percent of heart transplant recipients survive at least one year, and more than 75 percent survive five years. T ...
... transplant may be considered. Transplants increase life expectancy in persons with advanced heart failure who might otherwise be expected to live less than six months. Currently, 80 to 90 percent of heart transplant recipients survive at least one year, and more than 75 percent survive five years. T ...
materials and designs for 3d conformal
... and deoxygenated blood are collected into right atrium via vena cavae. Then the blood is transfer to the ventricles, completing the cardiac cycle. The valves located at the junctions make sure that the blood flows are unidirectional. The heart muscle, i.e. myocardium, is controlled by electrical si ...
... and deoxygenated blood are collected into right atrium via vena cavae. Then the blood is transfer to the ventricles, completing the cardiac cycle. The valves located at the junctions make sure that the blood flows are unidirectional. The heart muscle, i.e. myocardium, is controlled by electrical si ...
Printable TAVR Fact Sheet - Berks Cardiologists, Ltd.
... Indications: The Edwards SAPIEN transcatheter heart valve, model 9000TFX, sizes 23 mm and 26 mm, is indicated for patients with severe symptomatic calcified native aortic valve stenosis without severe aortic insufficiency and with ejection fraction >20% who have been examined by a heart team includi ...
... Indications: The Edwards SAPIEN transcatheter heart valve, model 9000TFX, sizes 23 mm and 26 mm, is indicated for patients with severe symptomatic calcified native aortic valve stenosis without severe aortic insufficiency and with ejection fraction >20% who have been examined by a heart team includi ...
3 stages
... cause of the functional (non-organic), heart murmur, and their distinctive features from the noise of organic origin. Functional (inorganic, innocent, random) noise. There are many causes and mechanisms of such noise in each case. Usually functional noises are heard over the top of the heart, at Bot ...
... cause of the functional (non-organic), heart murmur, and their distinctive features from the noise of organic origin. Functional (inorganic, innocent, random) noise. There are many causes and mechanisms of such noise in each case. Usually functional noises are heard over the top of the heart, at Bot ...
A not-so-rare form of heart failure in urban black Africans
... socio-demographic (including years of education and determining if a person was born in Soweto) and advanced clinical profiling, has been described previously.2 Echocardiography (according to goldstandard criteria12) and 12-lead electrocardiogram (ECG) (blinded classification to Minnesota criteria13 ...
... socio-demographic (including years of education and determining if a person was born in Soweto) and advanced clinical profiling, has been described previously.2 Echocardiography (according to goldstandard criteria12) and 12-lead electrocardiogram (ECG) (blinded classification to Minnesota criteria13 ...
Relation between myocardial infarct location and stroke
... From the Division of Cardiology, The Harris Chasanoff Heart Ins&% Department of Medicine, Long Island Jewish Medical Center, New Hyde Park and Long Island Campus for the Albert Einstein College OF Medicine, Bronx; *Department of Preventive Medicine and Community Health and Department of Medicine. Un ...
... From the Division of Cardiology, The Harris Chasanoff Heart Ins&% Department of Medicine, Long Island Jewish Medical Center, New Hyde Park and Long Island Campus for the Albert Einstein College OF Medicine, Bronx; *Department of Preventive Medicine and Community Health and Department of Medicine. Un ...
Energy metabolism patterns in mammalian myocardium adapted to
... per unit cross-sectional area is increased [58,59]. It remains to be understood whether a larger number of smaller mitochondria is adequate for the larger than normal contractile mass in the hypertrophied cardiomyocyte. Conceming the function of mitochondria, most earlier studies found normal oxidat ...
... per unit cross-sectional area is increased [58,59]. It remains to be understood whether a larger number of smaller mitochondria is adequate for the larger than normal contractile mass in the hypertrophied cardiomyocyte. Conceming the function of mitochondria, most earlier studies found normal oxidat ...
Cardiac Pacing
... leads this topic focuses, artificial cardiac pacemaker wikipedia - artificial cardiac pacemaker a pacemaker or artificial pacemaker so as not to be confused with the heart s natural pacemaker is a medical device which uses, temporary cardiac pacing uptodate - temporary cardiac pacing involves electr ...
... leads this topic focuses, artificial cardiac pacemaker wikipedia - artificial cardiac pacemaker a pacemaker or artificial pacemaker so as not to be confused with the heart s natural pacemaker is a medical device which uses, temporary cardiac pacing uptodate - temporary cardiac pacing involves electr ...
left ventricular cardiomyopathy in mitral valve prolapse: fact or fiction?
... excluded. In classic MVP, there was a significant reduction in global strain (-15.5±2.9%) compared with non-classic MVP (-18.7±3.8; p=0.0002) and control patients (-19.6±3.4%; p<0.0001). Transforming growth factor-β₁ (TGF-β1) and β₂ serum levels were elevated in the classic MVP group compared with t ...
... excluded. In classic MVP, there was a significant reduction in global strain (-15.5±2.9%) compared with non-classic MVP (-18.7±3.8; p=0.0002) and control patients (-19.6±3.4%; p<0.0001). Transforming growth factor-β₁ (TGF-β1) and β₂ serum levels were elevated in the classic MVP group compared with t ...
Acute Myocardial Infarction: A Century of Progress
... A second trial using mononuclear autologous bone marrow cells with favorable long term outcomes was also published recently. (Cao et al., 2009) Efforts are now underway to use gene therapy in AMI (Hammond and Tang, 2009) (Figure 13, see p. 194). In addition, left ventricular assist devices are becom ...
... A second trial using mononuclear autologous bone marrow cells with favorable long term outcomes was also published recently. (Cao et al., 2009) Efforts are now underway to use gene therapy in AMI (Hammond and Tang, 2009) (Figure 13, see p. 194). In addition, left ventricular assist devices are becom ...
Heart failure – biomarker effect and influence on quality of life.
... however there were no significant differences between the groups (Paper III). For responders the within group analysis showed improvement in four domains compared to the non-responders that improved in one domain; however there were no significant differences between the two groups. There were impro ...
... however there were no significant differences between the groups (Paper III). For responders the within group analysis showed improvement in four domains compared to the non-responders that improved in one domain; however there were no significant differences between the two groups. There were impro ...
The relationship between QT interval and QT dispersion with left
... and greater part of the heart is affected by LBBB than RBBB. So we must face to BBB, especially LBBB, more intensive than usual. In the LBBB, the prevalence of LVSDF in prolonged QT interval was more than normal group. This finding shows the correlation between QT interval and LVSF in LBBB. But in t ...
... and greater part of the heart is affected by LBBB than RBBB. So we must face to BBB, especially LBBB, more intensive than usual. In the LBBB, the prevalence of LVSDF in prolonged QT interval was more than normal group. This finding shows the correlation between QT interval and LVSF in LBBB. But in t ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.