• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Myocardial Mural Thickness During the Cardiac Cycle
Myocardial Mural Thickness During the Cardiac Cycle

... between diastole and systole. It was not possible to determine the magnitude of this error, but it was estimated to be small since special care was used to keep the spring tension as light as possible. The change in turgor of the myocardium during the ejection phase of systole is probably not very g ...
Articles in PresS. Am J Physiol Heart Circ Physiol (February 3, 2012
Articles in PresS. Am J Physiol Heart Circ Physiol (February 3, 2012

... contractility and diastolic stiffness. Increasingly anisotropic conduction velocity due to fibrosis ...
Echocardiographic Follow-Up of Patent Foramen Ovale and the
Echocardiographic Follow-Up of Patent Foramen Ovale and the

... posed by Radzik et al., 6 i.e. a value £ 3 mm was considered to be indicative of PFO. Although it is generally known that the cessation of interatrial shunt is not a clear-cut indicator of the anatomic closure of foramen ovale,9-11 we preferred the term “spontaneous closure of interatrial opening” f ...
Effects of Physiologic Pacing versus Ventricular Pacing on the Risk
Effects of Physiologic Pacing versus Ventricular Pacing on the Risk

New reference values for echocardiographic dimensions of healthy
New reference values for echocardiographic dimensions of healthy

... cardiac dimensions have to be compared with normal values. The reference range of values of each cardiac dimension has to be assessed from a population of normal hearts. Reference ranges were established in the early eighties by measuring cardiac dimensions of healthy Dutch children and adults by M- ...
Chlorine inhalationinduced myocardial depression and failure
Chlorine inhalationinduced myocardial depression and failure

Diurnal variations of the dominant cycle length of chronic atrial
Diurnal variations of the dominant cycle length of chronic atrial

... (19) blood pressure, body temperature, blood pH, hormone levels (25, 31, 34), and autonomic tone (10, 12). Furthermore, there are diurnal differences in levels of physical exertion, respiratory rate, and body posture. A number of these factors are likely to be interrelated and may contribute to diur ...
Print this article - Bangladesh Journals Online
Print this article - Bangladesh Journals Online

... criteria in this study was 50%, which is consistent with various other studies.10,11 In our study, most (66%) patients had concentric LVH and only 24% had eccentric LVH. This is due to the fact that pressure overload (e.g. hypertension, 68%) were more common than volume overload (e.g. multiple valvu ...
File - Cardiac Education
File - Cardiac Education

... 3. Calculate rate and axis. Measure intervals. Consider the diagnostic possibilities ...
Coronary Vessels
Coronary Vessels

... 1. Decreased blood flow in the coronary circulation due to occlusion by an embolus can result in ischemia and pain (angina pectoris) to the point of damaging heart tissue (myocardial infarction) 2. The most common area of occlusion is the anterior interventricular artery followed by the right corona ...
Chick Embryo - Circulation Research
Chick Embryo - Circulation Research

... systole as the beginning of isometric contraction displayed in the PA loop. The presence of isometric contraction and relaxation periods in each PA loop confirms previous observations that the atrioventricular and conotruncal cushions function as valves during the cardiac cycle.24 Retrograde flow th ...
pacemaker and iCd insertion procedure
pacemaker and iCd insertion procedure

Newly Diagnosed Atrial Fibrillation
Newly Diagnosed Atrial Fibrillation

... pericardial disease. Additional tests may be warrant- Study, among patients with stroke that was associed, including exercise testing to determine whether ated with atrial fibrillation, the arrhythmia was newthe patient has symptoms and to assess the heart ly diagnosed in 24 percent.20 Even among pa ...
11
11

... out that India has more number of cardiovascular deaths claiming younger population than in America [1]. The major reasons contributing to sudden deaths are due to myocardial infarction (commonly known as heart attack). Apart from deaths due to accidents myocardial infarction is the most commonly fo ...
Current Perceptions of the Epidemiology of Atrial Fibrillation
Current Perceptions of the Epidemiology of Atrial Fibrillation

... conferred a 1.4- and 1.6-fold AF risk and hypertension conferred a 1.5- and 1.4-fold risk after adjusting for other associated conditions. Diabetes was also found to be a significant independent predictor of AF in four other studies, associated with an average relative risk (RR) of 1.8; however, in ...
Atrial Fibrillation: Diagnosis and Treatment
Atrial Fibrillation: Diagnosis and Treatment

... narrow unless other conduction abnormalities exist (e.g., bundle branch block, accessory pathways). The ventricular response is often rapid, between 90 and 170 beats per minute. Atrial fibrillation is a source of significant morbidity and mortality because it impairs cardiac function and increases t ...
Fetal echocardiography: 20 years of progress - Heart
Fetal echocardiography: 20 years of progress - Heart

... The venous duct determines the flow of oxygenated blood to the left side of the circulation. It is a small conical structure, measuring 1–2 mm at its narrowest portion, connecting the intrahepatic part of the umbilical vein to the inferior caval vein, closing after birth. Doppler signals from this v ...
Atorvastatin Slows the Progression of Cardiac Remodeling
Atorvastatin Slows the Progression of Cardiac Remodeling

... Ventricular myocytes were isolated from neonatal rats at 2 to 3 days of life and cultured as described previously (8). In brief, the cardiomyocytes were incubated for 72 h in Dulbecco’s modified Eagle’s medium supplemented with 10% fetal calf serum and then grown for 48 h under serum-free conditions ...
Salivary Alpha-Amylase Activity, a New Biomarker in Heart Failure?
Salivary Alpha-Amylase Activity, a New Biomarker in Heart Failure?

... Diastolic Blood Pressure in mmHg; NT-proBNP = N-Terminal- proB-type Natriuretic Peptide; NYHA class: New York Heart Association (NYHA) Functional Classification ...
1 - Open Heart (BMJ)
1 - Open Heart (BMJ)

... haemodynamic data were not significantly different between the two groups. Similar results were reported from another centre, comparing the SJM Masters HP valve and the On-X valve.13 Another study suggested satisfactory early haemodynamic measurements of the On-X valve as compared with the literatur ...
Health‐related quality of life, depression, sleep and breathing  disorders in the elderly. With focus on those with impaired systolic 
Health‐related quality of life, depression, sleep and breathing  disorders in the elderly. With focus on those with impaired systolic 

... breathing (SDB) and sleep complaints, as well as to investigate the prognostic value of health-related quality of life (Hr-QoL) and depressive symptoms on mortality in an elderly community living population with a focus on those with impaired systolic function/heart failure (HF). Descriptive, progno ...
post CABG Myocardial Infarction : Latest Diagnostic and
post CABG Myocardial Infarction : Latest Diagnostic and

... but are at increased risk for adverse events and should be kept in a highly monitored environment (ICU) during their early postoperative periods. Prior to discharge to the ward, such patients should be medically optimized with: ...
Atrial fibrillation in pure rheumatic mitral valvular disease is
Atrial fibrillation in pure rheumatic mitral valvular disease is

... the atrial chamber and its remoulding, • the progressive thickening, fibrosis and calcification of the valvular system, could be the physiopathological link between the diseases. From this point of view, it is not already clear if left atrium dilatation, left atrium wall alteration and mural thrombo ...
Document
Document

... Etiology and Pathophysiology Healing Process • Scar tissue is present by day 10 – 14, but is weak • Healed by 6 weeks post MI • Ventricular remodeling – In attempt to compensate for the infarcted muscle, the normal myocardium will hypertrophy and dilate ...
Hereditary ATTR Thr60Ala Amyloidosis
Hereditary ATTR Thr60Ala Amyloidosis

... If there is orthostatic hypotension, elastic stockings may be recommended. Drug treatment with midodrine may also be helpful. Care should be taken to avoid dehydration if there is vomiting and diarrhoea. Intravenous fluids and anti-nausea drugs may be necessary. There are drugs that can help to cont ...
< 1 ... 110 111 112 113 114 115 116 117 118 ... 680 >

Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report