Neural Control of Heart Rate: a Comparison between
... left side were not distributed to the sinoatrial node. Randall et al. (34-37) also observed that left sympathetic stimulation sometimes evoked an increased arterial pulse pressure without concomitant changes in heart rate. He ascribed this increase in pulse pressure to an enhancement of ventricular ...
... left side were not distributed to the sinoatrial node. Randall et al. (34-37) also observed that left sympathetic stimulation sometimes evoked an increased arterial pulse pressure without concomitant changes in heart rate. He ascribed this increase in pulse pressure to an enhancement of ventricular ...
Prognostic Utility of Novel Biomarkers of Cardiovascular Stress
... calculated the integrated discrimination improvement, a measure of the ability of the model to improve average sensitivity without reducing average specificity.40 Last, we evaluated the ability of biomarkers to reclassify risk by examining the proportion of individuals reclassified correctly using t ...
... calculated the integrated discrimination improvement, a measure of the ability of the model to improve average sensitivity without reducing average specificity.40 Last, we evaluated the ability of biomarkers to reclassify risk by examining the proportion of individuals reclassified correctly using t ...
Ann Thorac Surg
... least 4 years for the lateral tunnel, and older than 6 years for the extracardiac conduit; McGoon ratio > 1.8 or PA index > 200, low PA pressure (< 15 mm Hg), and no AVVR. 2-stage procedure for high-risk patients (n=13). Result: 4 hospital deaths in the 1-stage group (operative mortality, 26.6%) No ...
... least 4 years for the lateral tunnel, and older than 6 years for the extracardiac conduit; McGoon ratio > 1.8 or PA index > 200, low PA pressure (< 15 mm Hg), and no AVVR. 2-stage procedure for high-risk patients (n=13). Result: 4 hospital deaths in the 1-stage group (operative mortality, 26.6%) No ...
Impact of Diet-Induced Weight Loss on the Cardiac Autonomic
... rMSSD and pNN50 are indices of parasympathetic modulation. NN intervals are the normal-to-normal intervals that include all intervals between adjacent QRS complexes resulting from sinus node depolarizations in the entire 24-hour electrocardiogram recording. The complete signal was carefully edited u ...
... rMSSD and pNN50 are indices of parasympathetic modulation. NN intervals are the normal-to-normal intervals that include all intervals between adjacent QRS complexes resulting from sinus node depolarizations in the entire 24-hour electrocardiogram recording. The complete signal was carefully edited u ...
Relation Between Left Ventricular Diastolic Pressure and Myocardial
... parameters of the ventricle's performance characteristics. Because of the complex arrangement of muscle fibers in the myocardium it is not feasible at the present time to study the behavior of any 1 fiber or any group of fibers having the same orientation in space. The problem of obtaining an indica ...
... parameters of the ventricle's performance characteristics. Because of the complex arrangement of muscle fibers in the myocardium it is not feasible at the present time to study the behavior of any 1 fiber or any group of fibers having the same orientation in space. The problem of obtaining an indica ...
Outcomes of patients with acute coronary syndromes and prior
... CK-MB concentration above the ULN or if there were new Q-waves in two ECG leads.10 In PARAGON-B, 5225 patients with non-ST-segment elevation ACS were randomly assigned to placebo or lamifiban adjusted for renal function. The primary endpoint was the composite of death, MI, or severe, recurrent ischae ...
... CK-MB concentration above the ULN or if there were new Q-waves in two ECG leads.10 In PARAGON-B, 5225 patients with non-ST-segment elevation ACS were randomly assigned to placebo or lamifiban adjusted for renal function. The primary endpoint was the composite of death, MI, or severe, recurrent ischae ...
Print - Circulation
... pressure and a gradually increasing ventricular pressure, and the mitral valve begins to close. Closure of the mitral valve is completed with the onset of ventricular systole and a rapid rise in ventricular pressure. In patients who have a high left ventricular initial diastolic pressure, usually du ...
... pressure and a gradually increasing ventricular pressure, and the mitral valve begins to close. Closure of the mitral valve is completed with the onset of ventricular systole and a rapid rise in ventricular pressure. In patients who have a high left ventricular initial diastolic pressure, usually du ...
state of michigan michigan administrative hearing system
... incidental findings of asymptomatic pancreatitis with elevation of amylase and lipase. Random glucose was 91, BUN 22, creatinine 1.1, and serum electrolytes were abnormal for hypokalemia of 3.4 and hypochloremia of 108. In addition, his alkaline phosphatase was elevated at 311 and his urinalysis was ...
... incidental findings of asymptomatic pancreatitis with elevation of amylase and lipase. Random glucose was 91, BUN 22, creatinine 1.1, and serum electrolytes were abnormal for hypokalemia of 3.4 and hypochloremia of 108. In addition, his alkaline phosphatase was elevated at 311 and his urinalysis was ...
Essential Opposite Roles of ERK and Akt Signaling in Cardiac
... by CS causes an increase in intracellular Na1, which, in turn, attenuates the Na1/Ca21 exchange activity, resulting in increased intracellular Ca21 concentration and consequently greater contractility. The reversion of the intracellular Ca21 to its basal levels depends on its sequestration in the sa ...
... by CS causes an increase in intracellular Na1, which, in turn, attenuates the Na1/Ca21 exchange activity, resulting in increased intracellular Ca21 concentration and consequently greater contractility. The reversion of the intracellular Ca21 to its basal levels depends on its sequestration in the sa ...
Samuel Frazer Sears Jr., Ph.D. PERSONAL INFORMATION East Carolina University
... & Sears, S.F. (2010). Cardiac resynchronization therapy: A pilot study examining cognitive change in patients before and after treatment. Clinical Cardiology, 33, 84-88. 36) Kong, M.H., Peterson, E.D., Fonarow, G.C., Sanders, G.D., Yancy, C.W., Russo, A.M., Curtis, A.B., Sears, S.F., Thomas, K.L., C ...
... & Sears, S.F. (2010). Cardiac resynchronization therapy: A pilot study examining cognitive change in patients before and after treatment. Clinical Cardiology, 33, 84-88. 36) Kong, M.H., Peterson, E.D., Fonarow, G.C., Sanders, G.D., Yancy, C.W., Russo, A.M., Curtis, A.B., Sears, S.F., Thomas, K.L., C ...
Increased plasma arginine vasopressin levels in patients
... The antidiuretic hormone argmme vasopressin could contribute to both the vasoconstriction and impaired water handling frequently found in patients with congestive heart failure. In order to determine basal levels for vasopressin in this condition, plasma vasopressin was measured by radioimmunoassay ...
... The antidiuretic hormone argmme vasopressin could contribute to both the vasoconstriction and impaired water handling frequently found in patients with congestive heart failure. In order to determine basal levels for vasopressin in this condition, plasma vasopressin was measured by radioimmunoassay ...
Impact of a New Conduction Defect After Transcatheter Aortic Valve
... Aachen and Cologne, Germany Objectives This study sought to evaluate the impact of new conduction defects after transcatheter aortic valve implantation (TAVI) on the evolution of left ventricular (LV) function during 1-year follow-up. Background New left bundle branch block (LBBB) or need for perman ...
... Aachen and Cologne, Germany Objectives This study sought to evaluate the impact of new conduction defects after transcatheter aortic valve implantation (TAVI) on the evolution of left ventricular (LV) function during 1-year follow-up. Background New left bundle branch block (LBBB) or need for perman ...
Atrial Electrophysiological Remodeling and Fibrillation in Heart Failure
... (mainly tachypacing-induced or myocardial infarction (MI)induced HF).5 In atria of dogs with short-term (three–six weeks) ventricular tachypacing-induced HF, the inducibility and duration of sustained AF 21 or atrial tachycardia (AT)22 were substantially enhanced. Focal activations were commonly see ...
... (mainly tachypacing-induced or myocardial infarction (MI)induced HF).5 In atria of dogs with short-term (three–six weeks) ventricular tachypacing-induced HF, the inducibility and duration of sustained AF 21 or atrial tachycardia (AT)22 were substantially enhanced. Focal activations were commonly see ...
Right Ventricular Hypertrophy
... the right, it lies only slightly anterior to the E point, hence the relatively small R in V1. The placement of the electrodes in the various systems currently in use in ve.toreardiography does not represent an ideal method for the evaluation of the electric forces of the heart. But even with such de ...
... the right, it lies only slightly anterior to the E point, hence the relatively small R in V1. The placement of the electrodes in the various systems currently in use in ve.toreardiography does not represent an ideal method for the evaluation of the electric forces of the heart. But even with such de ...
2005 American Heart Association Guidelines for Cardiopulmonary
... hours after onset of symptoms, summarizing key out-of-hospital, ED, and some initial critical-care topics that are relevant to stabilization. They also continue to build on recommendations from the ACC/AHA Guidelines,11,12 which are used throughout the United States and Canada.13 As with any medical ...
... hours after onset of symptoms, summarizing key out-of-hospital, ED, and some initial critical-care topics that are relevant to stabilization. They also continue to build on recommendations from the ACC/AHA Guidelines,11,12 which are used throughout the United States and Canada.13 As with any medical ...
Heart failure with preserved ejection fraction: chronic low
... Downloaded from http://jap.physiology.org/ by 10.220.33.4 on June 14, 2017 ...
... Downloaded from http://jap.physiology.org/ by 10.220.33.4 on June 14, 2017 ...
Double outlet right ventricle with intact ventricular
... vegetation are among VSD closure mechanisms.[1,9] According to Somerville et al.,[10] chances of spontaneous closure of VSDs that reach the inlet region, have subaortic or subpulmonic localization or resemble “swiss cheese” in shape are low. However, VSDs localized in the inferior portion of the tri ...
... vegetation are among VSD closure mechanisms.[1,9] According to Somerville et al.,[10] chances of spontaneous closure of VSDs that reach the inlet region, have subaortic or subpulmonic localization or resemble “swiss cheese” in shape are low. However, VSDs localized in the inferior portion of the tri ...
Print - Circulation
... appropriate in each case, either by excision of a 3-mm ellipse of epimyocardium or by use of a transmural needle bioptome (diameter, 1.5 mm) from which the epimyocardial end was used for study. All biopsies obtained at routine surgery were taken immediately after the heart was arrested on cardiopulm ...
... appropriate in each case, either by excision of a 3-mm ellipse of epimyocardium or by use of a transmural needle bioptome (diameter, 1.5 mm) from which the epimyocardial end was used for study. All biopsies obtained at routine surgery were taken immediately after the heart was arrested on cardiopulm ...
A Critical Analysis of the Scientific Evidence Behind International
... College of Cardiology/American Heart Association/European Society of Cardiology; Class I, conditions for which there is evidence and/or a general agreement that a given procedure/therapy is beneficial, useful and effective; Class II, conditions for which there is conflicting evidence and/or a diverg ...
... College of Cardiology/American Heart Association/European Society of Cardiology; Class I, conditions for which there is evidence and/or a general agreement that a given procedure/therapy is beneficial, useful and effective; Class II, conditions for which there is conflicting evidence and/or a diverg ...
Effects of myocardial ischemia on the release of cardiac troponin i in
... In our study, the concentration of cardiac troponin I was significantly higher in group III than in groups I and II and in group II compared with group I. The concentration of cardiac troponin I increased as the ischemic period increased. CK-MB and LD concentrations did not show a similar evolution. ...
... In our study, the concentration of cardiac troponin I was significantly higher in group III than in groups I and II and in group II compared with group I. The concentration of cardiac troponin I increased as the ischemic period increased. CK-MB and LD concentrations did not show a similar evolution. ...
Arterial - Todo Corazón de Murcia
... giography. There have been sporadic reports of myocardial ischemia or sudden death in children after arterial switch repair, possibly related to inadequate coronary perfusion.2,3,5,7,9 To our knowledge, our study presents the third published data on exercise tolerance in children after arterial swit ...
... giography. There have been sporadic reports of myocardial ischemia or sudden death in children after arterial switch repair, possibly related to inadequate coronary perfusion.2,3,5,7,9 To our knowledge, our study presents the third published data on exercise tolerance in children after arterial swit ...
Echocardiographic Follow-Up of Patent Foramen Ovale and the
... posed by Radzik et al., 6 i.e. a value £ 3 mm was considered to be indicative of PFO. Although it is generally known that the cessation of interatrial shunt is not a clear-cut indicator of the anatomic closure of foramen ovale,9-11 we preferred the term “spontaneous closure of interatrial opening” f ...
... posed by Radzik et al., 6 i.e. a value £ 3 mm was considered to be indicative of PFO. Although it is generally known that the cessation of interatrial shunt is not a clear-cut indicator of the anatomic closure of foramen ovale,9-11 we preferred the term “spontaneous closure of interatrial opening” f ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.