1 General IntroductIon Pulmonary arterIal
... In Chapter 4, β-blocker therapy was evaluated. Beta-blocker therapy is a well-established treatment for left heart failure, but strongly discouraged in PH, due to its negative inotropic and chronotropic effects. We hypothesized that β-blocker therapy in PH is tolerated, if carefully introduced, and ...
... In Chapter 4, β-blocker therapy was evaluated. Beta-blocker therapy is a well-established treatment for left heart failure, but strongly discouraged in PH, due to its negative inotropic and chronotropic effects. We hypothesized that β-blocker therapy in PH is tolerated, if carefully introduced, and ...
Plasma Bin1 Correlates With Heart Failure And Predicts
... fibrofatty replacement of the right ventricular myocardium and associated arrhythmias that originate from the right ventricle. BIN1 is a membrane-associated protein that is involved in cardiac T-tubule homeostasis and is down-regulated in cardiomyopathy. BIN1 has also been shown to be essential to t ...
... fibrofatty replacement of the right ventricular myocardium and associated arrhythmias that originate from the right ventricle. BIN1 is a membrane-associated protein that is involved in cardiac T-tubule homeostasis and is down-regulated in cardiomyopathy. BIN1 has also been shown to be essential to t ...
Interventricular Septal Thickness and Left Ventricular Hypertrophy
... SUMMARY Septal and left ventricular posterior wall (LVPW) thicknesses and their ratios were studied at the left ventricular outflow tract and left ventricular cavity in 66 patients with echocardiographically diagnosed left ventricular concentric hypertrophy, 20 with idiopathic hypertrophic subaortic ...
... SUMMARY Septal and left ventricular posterior wall (LVPW) thicknesses and their ratios were studied at the left ventricular outflow tract and left ventricular cavity in 66 patients with echocardiographically diagnosed left ventricular concentric hypertrophy, 20 with idiopathic hypertrophic subaortic ...
Reversed closure sequence of the mitral and tricuspid
... first heart scald) have been reported in several disease statzs. With Ebstein’s anomaly, right bundle branch block or stopic rhythms originating from the left ventricle, the closure sequence is maintained but the interval between mitral and tricuspid valve closure is prolonged (9.10). Reversal ofthe ...
... first heart scald) have been reported in several disease statzs. With Ebstein’s anomaly, right bundle branch block or stopic rhythms originating from the left ventricle, the closure sequence is maintained but the interval between mitral and tricuspid valve closure is prolonged (9.10). Reversal ofthe ...
Interventricular Septal Thickness and Left Ventricular
... SUMMARY Septal and left ventricular posterior wall (LVPW) thicknesses and their ratios were studied at the left ventricular outflow tract and left ventricular cavity in 66 patients with echocardiographically diagnosed left ventricular concentric hypertrophy, 20 with idiopathic hypertrophic subaortic ...
... SUMMARY Septal and left ventricular posterior wall (LVPW) thicknesses and their ratios were studied at the left ventricular outflow tract and left ventricular cavity in 66 patients with echocardiographically diagnosed left ventricular concentric hypertrophy, 20 with idiopathic hypertrophic subaortic ...
Experiment HH-8: Heart Sounds
... Pulmonic, which is located in the second intercostal space at the left sternal border, #2. At this location, the systolic murmur of pulmonic stenosis and the diastolic murmur of pulmonic regurgitation are the loudest. ...
... Pulmonic, which is located in the second intercostal space at the left sternal border, #2. At this location, the systolic murmur of pulmonic stenosis and the diastolic murmur of pulmonic regurgitation are the loudest. ...
Brain natriuretic peptide release in acute myocardial infarction
... release. Aim of this study was to observe BNP release in acute myocardial infarction (AMI). We measured BNP in patients with AMI. Control group (n=) was similar by age and gender to AMI group. We found statistically significant elevation of BNP compared to controls (. pg/ml vs . pg/ml ...
... release. Aim of this study was to observe BNP release in acute myocardial infarction (AMI). We measured BNP in patients with AMI. Control group (n=) was similar by age and gender to AMI group. We found statistically significant elevation of BNP compared to controls (. pg/ml vs . pg/ml ...
12 Lead ECGs: Ischemia, Injury, Infarction
... RN.com acknowledges the valuable contributions of… ...Tanna R. Thomason, RN, MS, CCRN, author of 12 Lead ECG Interpretation: Ischemia, Injury and Infarction. Tanna has over 20 years of experience as a clinician in the hospital setting. After completing her Master’s Degree as a Clinical Nurse Special ...
... RN.com acknowledges the valuable contributions of… ...Tanna R. Thomason, RN, MS, CCRN, author of 12 Lead ECG Interpretation: Ischemia, Injury and Infarction. Tanna has over 20 years of experience as a clinician in the hospital setting. After completing her Master’s Degree as a Clinical Nurse Special ...
Pregnancy Complicated by Valvular Heart Disease: An Update
... observed in VHD patients than in any other patient subgroup, which included those with congenital heart disease, cardiomyopathy, and ischemic heart disease. Furthermore, postpartum hemorrhage was frequently encountered in the VHD group, likely related to the use of anticoagulant medications.5 Matern ...
... observed in VHD patients than in any other patient subgroup, which included those with congenital heart disease, cardiomyopathy, and ischemic heart disease. Furthermore, postpartum hemorrhage was frequently encountered in the VHD group, likely related to the use of anticoagulant medications.5 Matern ...
Update on resuscitation: The 2015 AHA Resuscitation guidelines
... 1966 and since then the American Heart Association (AHA) has revised the guidelines every 4- 6 years. The 2015 guidelines marked 49 years since the first publication, a reminder that this is a relatively young aspect of modern medicine.[1] Earlier descriptions of succesful resuscitation efforts incl ...
... 1966 and since then the American Heart Association (AHA) has revised the guidelines every 4- 6 years. The 2015 guidelines marked 49 years since the first publication, a reminder that this is a relatively young aspect of modern medicine.[1] Earlier descriptions of succesful resuscitation efforts incl ...
Slide Set - Professional Heart Daily
... Elements collected should include TICI or TIMI grades prior to and after reperfusion ...
... Elements collected should include TICI or TIMI grades prior to and after reperfusion ...
effects of a randomized controlled trial of diet and/or exercise on
... MVPA was the only PA variable found to be significantly correlated with both changes in VO2peak (r = 0.329) and changes in body weight (r = 0.387). CONCLUSION: Results of this 20 week study suggest that exercise and diet is the most effective short-term combination for weight loss and for increasing ...
... MVPA was the only PA variable found to be significantly correlated with both changes in VO2peak (r = 0.329) and changes in body weight (r = 0.387). CONCLUSION: Results of this 20 week study suggest that exercise and diet is the most effective short-term combination for weight loss and for increasing ...
Cardio-oesophageal reflex in humans as a mechanism for `linked
... the J point. The left ventricle and the coronary arteries recordings were performed in multiple projections. The were completely normal on angiography and this was proximal left anterior descending coronary artery was confirmed by two independent observers. Patients with centred for optimal viewing ...
... the J point. The left ventricle and the coronary arteries recordings were performed in multiple projections. The were completely normal on angiography and this was proximal left anterior descending coronary artery was confirmed by two independent observers. Patients with centred for optimal viewing ...
PDF
... of ximelagatran from the market and termination of its development based on concerns over safety.9 Aspirin, other antiplatelet agents, and oral vitamin K antagonists are available in the US and other countries for cardiovascular disease prevention. Either aspirin or warfarin when given alone and acc ...
... of ximelagatran from the market and termination of its development based on concerns over safety.9 Aspirin, other antiplatelet agents, and oral vitamin K antagonists are available in the US and other countries for cardiovascular disease prevention. Either aspirin or warfarin when given alone and acc ...
ESC Guidelines for cardiac pacing and cardiac resynchronization
... outside specialists for review. The document is revised, and finally approved by the CPG and subsequently published. After publication, dissemination of the message is of paramount importance. Pocket-sized versions and personal digital assistant-downloadable versions are useful at the point of care. ...
... outside specialists for review. The document is revised, and finally approved by the CPG and subsequently published. After publication, dissemination of the message is of paramount importance. Pocket-sized versions and personal digital assistant-downloadable versions are useful at the point of care. ...
Syncope - UC Irvine`s Department of Medicine
... or ECG features suggesting an arrhythmic syncope ...
... or ECG features suggesting an arrhythmic syncope ...
Heart Sounds
... Pulmonic, which is located in the second intercostal space at the left sternal border, #2. At this location, the systolic murmur of pulmonic stenosis and the diastolic murmur of pulmonic regurgitation are the loudest. ...
... Pulmonic, which is located in the second intercostal space at the left sternal border, #2. At this location, the systolic murmur of pulmonic stenosis and the diastolic murmur of pulmonic regurgitation are the loudest. ...
Cardiovascular mortality and N-terminal- proBNP reduced after combined selenium and
... Coenzyme Q10 (also termed ubiquinone) is present in all cells of the body and has a central role as an electron carrier in the mitochondrial respiratory chain and in oxidative phosphorylation. Extra-mitochondrial coenzyme Q10 is also an efficient lipid soluble antioxidant, protecting against lipid p ...
... Coenzyme Q10 (also termed ubiquinone) is present in all cells of the body and has a central role as an electron carrier in the mitochondrial respiratory chain and in oxidative phosphorylation. Extra-mitochondrial coenzyme Q10 is also an efficient lipid soluble antioxidant, protecting against lipid p ...
Prognostic Utility of Novel Biomarkers of Cardiovascular Stress
... calculated the integrated discrimination improvement, a measure of the ability of the model to improve average sensitivity without reducing average specificity.40 Last, we evaluated the ability of biomarkers to reclassify risk by examining the proportion of individuals reclassified correctly using t ...
... calculated the integrated discrimination improvement, a measure of the ability of the model to improve average sensitivity without reducing average specificity.40 Last, we evaluated the ability of biomarkers to reclassify risk by examining the proportion of individuals reclassified correctly using t ...
Emerging mechanisms of T-tubule remodelling in heart failure
... T-tubule system of a myocyte. The appreciation of T-tubule remodelling in heart disease was boosted during the last decade by the application of laser scanning confocal microscopy and the use of fluorescent lipophilic membrane markers. Among these, He et al. 53 were the first to identify and quantif ...
... T-tubule system of a myocyte. The appreciation of T-tubule remodelling in heart disease was boosted during the last decade by the application of laser scanning confocal microscopy and the use of fluorescent lipophilic membrane markers. Among these, He et al. 53 were the first to identify and quantif ...
ACLS Pretest - Heartland CPR
... and treat as VTG. With advanced rhythm training, you will learn that WCTs may be abnormally conducted supraventricular rhythms and “look like” VT. Careful examination of a rhythm strip attempts to identify atrioventricular dissociation (not shown here). The atria in VT continue to contract in most i ...
... and treat as VTG. With advanced rhythm training, you will learn that WCTs may be abnormally conducted supraventricular rhythms and “look like” VT. Careful examination of a rhythm strip attempts to identify atrioventricular dissociation (not shown here). The atria in VT continue to contract in most i ...
Effects of mitral valve regurgitation in the dog on the right ventricle
... LA at low pressure before the aortic valve opens. This means that the load on the heart is not great as the lesions develop slowly, and the large regurgitant volume is well accommodated for years, as both the LV and LA remodel and remain compliant, accommodating the large volumes (Lord 1976, Pape a ...
... LA at low pressure before the aortic valve opens. This means that the load on the heart is not great as the lesions develop slowly, and the large regurgitant volume is well accommodated for years, as both the LV and LA remodel and remain compliant, accommodating the large volumes (Lord 1976, Pape a ...
Balloon Valvuloplasty as a Treatment of Congenital
... values comparing to the initial PG. We decided not to perform another BVP with larger balloon in these 11 patients, because of major aortic regurgitation or their young age. During the follow up period, BVP was performed again in 4 of these 11 patients, 9 to 48 months after the first interventional ...
... values comparing to the initial PG. We decided not to perform another BVP with larger balloon in these 11 patients, because of major aortic regurgitation or their young age. During the follow up period, BVP was performed again in 4 of these 11 patients, 9 to 48 months after the first interventional ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.