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Myocardial Volume and Organization Are Changed by Failure of
Myocardial Volume and Organization Are Changed by Failure of

... the definitive myocardium to the cardiac outflow tract. The current study was undertaken to understand the changes in myocardial characteristics in the heart tube, including volume, proliferation, and cell size when the myocardium from the secondary heart field fails to be added to the primary heart tu ...
Uncontrolled ventricular rate in atrial fibrillation - Heart
Uncontrolled ventricular rate in atrial fibrillation - Heart

... A 33-year-old woman presented with increasing lateral projections) showed mild cardiomegaly, shortness of breath and a rapid irregular pulse. left atrial enlargement, and pulmonary vascular At age 8 she experienced an episode of acute redistribution. The echocardiogram showed normal rheumatic fever. ...
Standard transthoracic echocardiography and transesophageal
Standard transthoracic echocardiography and transesophageal

... (see Figure 1). The anterior leaflet is trapezoidal in shape, devoid of any well-defined indentations, extends vertically and is taller in height than the posterior leaflet. Via its attachment to one third of the circumference of the annulus, the anterior leaflet is also anchored to the fibrous port ...
Characterization of heart and pulmonat vacular
Characterization of heart and pulmonat vacular

... Diabetes mellitus is a group of diseases characterized by elevated blood glucose concentration. It may be a consequence of either the body does not produce enough insulin or because cells do not respond to the insulin that is produced. Diabetes is major cause to cardiovascular disease which lead to ...
Curriculum Vitae - Amazon Web Services
Curriculum Vitae - Amazon Web Services

... bundle branch block. Non-contact mapping records global activation from an entire cardiac chamber on a beat-by-beat basis thereby enabling insights previously only possible using animal models. In addition to being trained as an advanced user of the non-contact system (in the institution in which it ...
Aldo-HF trial - Dr Richard Bogle
Aldo-HF trial - Dr Richard Bogle

... a Data are expressed as mean (SD) unless otherwise specified. Higher values indicate better performance for LV ejection fraction, medial e’ wave velocity, duration of exercise, peak V̇O2, ATVO2, Borg scale, walk distance, SF-36 Physical Functioning Scale, and SF-36 global self assessment. Lower valu ...
Recommendations for interpretation of 12
Recommendations for interpretation of 12

... manifests as an isolated increase of QRS amplitude, with normal QRS axis, normal atrial and ventricular activation patterns, and normal ST-segment T-wave repolarization.14,24,33,41,43,46 – 48 A high prevalence of ECGs that fulfil Sokolow–L ...
Haemodynamic Alterations Induced By Cardiac Pacing: Is Clinical
Haemodynamic Alterations Induced By Cardiac Pacing: Is Clinical

... result in a reduction of left ventricular (LV) function, myocardial perfusion defects and severe heart failure. A negative effect of RV pacing was proven in a large cohort study of 11.426 patient who underwent pacemaker implantation.2 The authors reported a significant increase of heart failure even ...
Relationship of Number of Phases per Cardiac Cycle and Accuracy
Relationship of Number of Phases per Cardiac Cycle and Accuracy

... lower and higher heart rates. All comparisons were two-tailed, and a p value of < 0.05 was considered as statistically significant. Figure 3. Relative change (delta) of the timing of enddiastole (ED) and end-systole (ES) for acquisitions using 8, 11, 14, and 17 phases per cardiac cycle, compared to ...
Anatomy of the Heart of the Amphibia II. Cryptobranchus alleganiensis
Anatomy of the Heart of the Amphibia II. Cryptobranchus alleganiensis

... right lateral coronary vein is found along the surface of the ventricle and originates from dorsal and ventral vessels on the conus arteriosusand terminates at the right duct of Cuvier only after coursingthrough the posterior region of the cardiac ligament; smaller coronary veins from the dorsaland ...
Targeted ablation of cardiac sympathetic neurons - AJP
Targeted ablation of cardiac sympathetic neurons - AJP

... therapy for ventricular arrhythmias. For example, ␤-adrenergic-receptor blockade reduces mortality due to sudden death by 30 –50% (14, 29, 39, 53, 56). However, despite these favorable outcomes, the mortality following myocardial infarction, even when placed on optimal ␤-adrenergic-receptor antagoni ...
Vasodilator therapy for acute myocardial infarction and
Vasodilator therapy for acute myocardial infarction and

... side can decrease characteristic impedance and increase ventricular ejection without changing arterial pressure (27). These studies indicate that a vasodilator-induced increase in arterial compliance is a potentially important mechanism for improving left ventricular function during vasodilator ther ...
Pulmonary Arterial Hypertension: A Two
Pulmonary Arterial Hypertension: A Two

... one of the most common measures of RV systolic function obtained using M-mode echocardiography and is recommended by the American society of echocardiography’s guideline for the routine evaluation of RV function. Although TAPSE measures the longitudinal motion of the RV, it has a good correlation wi ...
Syncope: Distinguishing the Vanilla Faint From a Sudden Cardiac
Syncope: Distinguishing the Vanilla Faint From a Sudden Cardiac

... 500,000 new syncope patients each year 5 170,000 have recurrent syncope 6 70,000 have recurrent, infrequent, unexplained syncope 1-4 ...
Arrhythmia - PACT
Arrhythmia - PACT

... hum’ at 50 Hz) was detected in time. Always remember to check that the rhythm you observe is real: lead disconnections can cause apparent VF as well as asystole. Check the rhythm on two other leads and check the patient’s pulse or the displayed arterial tracing. Similarly, the tracing of pulse oxime ...
Verapamil-induced polymorphous ventricular tachycardia
Verapamil-induced polymorphous ventricular tachycardia

... patients with poor left ventricular function secondary to the drug's negative inotropic and hypotensive effects. This report describes another potential complication of intravenous verapamil administration, polymorphous ventricular tachycardia, during the conversion of paroxysmal supraventricular ta ...
DISORDER OF CARDIAC RHYTHM
DISORDER OF CARDIAC RHYTHM

... vasodilators, calcium channel blockers slow, α-blockers, diuretics, chime, etc.). Some of these drugs (dihydropyridine calcium antagonists group) have no direct effect on the function of the SA-node, causing the so-called reflex tachycardia. Intracardiac factors. • chronic heart failure; • myocardia ...
Dyspnea, Orthopnea, and Paroxysmal Nocturnal Dyspnea
Dyspnea, Orthopnea, and Paroxysmal Nocturnal Dyspnea

... Orthopnea is caused by pulmonary congestion during recumbency . In the horizontal position there is redistribution of blood volume from the lower extremities and splanchnic beds to the lungs . In normal individuals this has little effect, but in patients in whom the additional volume cannot be pumpe ...
Prolonged temporary cardiac pacing using subcutaneous
Prolonged temporary cardiac pacing using subcutaneous

... required for prolonged periods, particularly in patients with severe infection and bradyarrhythmias who may need several weeks of antibiotic treatment before a permanent pacemaker can be safely implanted. Prolonged temporary transvenous pacing is frequently associated with complications such as loca ...
Structural and functional changes in maternal left ventricle during
Structural and functional changes in maternal left ventricle during

... Despite many reports on maternal cardiac adaption being published, there is controversy about the change in left ventricular (LV) performance during pregnancy. Although it is reported that an increased cardiac output (CO) is paralleled by a decreased peripheral vascular resistance, the documents on ...
Determinants of Duration and Mean Rate of Ventricular Ejection
Determinants of Duration and Mean Rate of Ventricular Ejection

... contraction and relaxation which might occur,4 those factors modifying the duration and mean rate of ventricular ejection have a reciprocal influence on the duration and mean rate of ventricular filling. One interesting implication of this relates to the dynamic alterations accompanying mitral or tr ...
Body, eye, and chorioallantoic vessel growth are not dependent on
Body, eye, and chorioallantoic vessel growth are not dependent on

... relationship between cardiac output (and the associated nutrient delivery and waste removal) and tissue growth and development. That is, although embryos may survive complete elimination of cardiac output, under less severe situations is there a graded effect whereby there is a threshold level of bl ...
Living anatomy of the atrioventricular junctions
Living anatomy of the atrioventricular junctions

... Society of Pacing and Electrophysiology. It proposes a new, anatomically sound, nomenclature that will be applicable to all chambers of the heart. In this report, we discuss its value as regards the description of the atrioventricular junctions, establishing the principles of this new nomenclature. ...
Outcomes Related to First-Degree Atrioventricular Block and
Outcomes Related to First-Degree Atrioventricular Block and

... atrioventricular nodal artery (which originates from the right coronary artery in 90% of people (36). The interventricular conduction system is supplied by the penetrating branches of the left anterior descending coronary artery. Coronary artery disease has been etiologically linked to higher (secon ...
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C:\Documents and Settings\Reb...uhi.default\Cache\0F1E60D5d01

... Regional inhomogeneities in contractility and mechanical restitution may serve as foci for stretch-induced arrhythmias (SIAs). These inhomogeneities can be attributed to localized ischemia (12, 42) or hypertrophy localized to various regions on the ventricular free wall and septum (11). Such inhomog ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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