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Severe left anterior descending artery stenosis
Severe left anterior descending artery stenosis

... would afford equivalent outcomes compared to more “conventional” stents remain to be seen and should be the subject of further trials. ...
STATE OF ART ON TRANSCATHETER AORTIC VALVE
STATE OF ART ON TRANSCATHETER AORTIC VALVE

... of inoperable patients of the PARTNER study(2), the 30-day mortality was 5.0% in the TAVI group (Transfemoral approach in all patients) and 2.8% in the group of medical treatment (p = 0.41). It's important point out that, up to 84% of patients in the group of medical treatment was subjected to at le ...
Intraoperative Recording of Specialized Atrioventricular Conduction
Intraoperative Recording of Specialized Atrioventricular Conduction

... We successfully mapped 14 patients with incomplete AV canal. The median age at surgery of this group was 9 years. None developed complete heart block postoperatively, although two patients developed symptomatic tachy-bradyarrhythmia syndrome and one (patient 1 1) had intermittent junctional mechanis ...
Click here for handout
Click here for handout

... heart disease “Congenital affections of the heart have only a limited clinical interest, as in a large proportion of the cases the anomaly is not compatible with life, and in others nothing can be done to remedy the defect or even relieve symptoms.” Sir William Osler 1892 ...
Aalborg Universitet Death and Life-Threatening Arrhythmias After Myocardial Infarction
Aalborg Universitet Death and Life-Threatening Arrhythmias After Myocardial Infarction

... prevention with an implantable cardioverterdefibrillator (ICD) is recommended in patients with left ventricular ejection fraction (LVEF) #35% and symptomatic congestive heart failure (HF) at least 40 days after an acute MI (1). Although the absolute risk for SCD is highest in patients with significant ...
1-s2.0-S1936878X13004440-main - VBN
1-s2.0-S1936878X13004440-main - VBN

... prevention with an implantable cardioverterdefibrillator (ICD) is recommended in patients with left ventricular ejection fraction (LVEF) #35% and symptomatic congestive heart failure (HF) at least 40 days after an acute MI (1). Although the absolute risk for SCD is highest in patients with significant ...
The visualization and measurement of left ventricular deformation
The visualization and measurement of left ventricular deformation

... Permanently damaged muscle is replaced by scar tissue, which does not contract like healthy heart tissue, and sometimes becomes very thin and bulges during each heart beat (aneurysm) [11,2]. The analysis of myocardial function is important for the diagnosis of heart diseases, the planning of therapy ...
Despite the many decades of intensive research, left ventricular
Despite the many decades of intensive research, left ventricular

... other hand, spironolactone in this experiment improved NO synthase activity in both, LV and kidney, indicating improved NO production. Moreover, it has been shown previously in our laboratory that spironolactone increased both thiol and nitrosothiol groups in the kidney (Pecháňová et al. 2006). Both ...
Right heart failure in the intensive care unit
Right heart failure in the intensive care unit

... minimal change in generated pressure or output [3]. Because the pulmonary circulation is normally a very low resistance circuit, moderate or even severe right-ventricular contractile dysfunction does not necessarily cause RHF in the absence of elevated pulmonary arterial pressure. Conversely, in the ...
Fluoroless cryo-ablation of para
Fluoroless cryo-ablation of para

... interval as well as AV blocks during cryo-mapping are completely reversible and are not permanent  (2,3), compared to radiofrequency ablation of antero-septal accessory pathways, in which the risk of permanent AV block is reported to be up to 2.7 % (4). Although the acute procedural success rate of ...
Tetralogy of Fallot with Anomalous Left Anterior Descending
Tetralogy of Fallot with Anomalous Left Anterior Descending

... syndrome(LCOS) and sudden death.20 We have avoided a ventriculotomy into the RV body, limited it to the outlet portion of RV ie., infundibulum which has a relatively minor functional contribution to RV stroke volume. TA approach may be used, particularly when a ventriculotomy is dangerous due to unf ...
Evaluation of arrhythmias in the late hospital phase - Heart
Evaluation of arrhythmias in the late hospital phase - Heart

... acute myocardial infarction: coronary care unit ventricular tachycardia I0 per cent of patients (Marshall, Blount, and Genton, I968) and 8 per cent of coronary care unit. ...
Anomalous origin of left main coronary artery from the right sinus of
Anomalous origin of left main coronary artery from the right sinus of

... vigorous physical activity can occur at any age, but since most competitive athletes are under age 50, sudden death secondary to a cardiac anomalous artery occurs more frequently in the younger age group [20]. The physiological demands of physical exercise depend on type of exercise. Dynamic or isom ...
Neurocardiogenic syncope
Neurocardiogenic syncope

... Summary Mechanism of tilt induced syncope Bezold-Jarisch Reflex Venous pooling - Vigorously contracting yet small sized ventricle Ventricular mechanoreceptor stimulation muscle bed vasodilatation and cardiac slowing ...
The relationship between mitral annular systolic velocity and
The relationship between mitral annular systolic velocity and

... echocardiography. Echocardiography was performed in a left lateral decubitus position, with a digital commercial harmonic imaging ultrasound system, АLOKA PROSOUND SSD5500 SV, equipped with a 2.5 MHz phasedarray transducer. The images were acquired during a breath hold. Left ventricular dimensions w ...
Stroke Volume Dynamics During Progressive Exercise in Healthy
Stroke Volume Dynamics During Progressive Exercise in Healthy

... tance). Changes in stroke volume thus reflect the combined influences of these factors while serving as a prime indicator of the overall effectiveness of the cardiac pump. This traditional model of the role of stroke volume in reflecting the role of the heart as the primary controller of circulatory ...
Intracardiac flow separation in Python
Intracardiac flow separation in Python

... (2) Effects of altering output pressures Filling pressures were readjusted to attain control level flows at output pressures of 6.5 kPa. Then, output pressure of the systemic or the pulmonary circulation was reduced abruptly to 1 kPa followed by stepwise increases (1 kPa for each step) until an outf ...
Birger Axelsson - Umeå universitet
Birger Axelsson - Umeå universitet

... positive effect on systolic function in combination with milrinone. Conclusions: We conclude that milrinone treatment leads to an increase in blood flow in newly implanted coronary saphenous vein grafts, and improves ventricular relaxation postcardiopulmonary bypass. Neither milrinone nor levosimend ...
33592-Review - F6 Publishing Home
33592-Review - F6 Publishing Home

... not limited to the distribution of an epicardial coronary artery. A disease primarily afflicting post-menopausal women, it is frequently mistaken for acute anterior wall myocardial infarction. Alternatively called Stress Cardiomyopathy, physical or emotional triggers are identified in only three fou ...
THE ANGLE OF ELECTRICAL CARDIAC AXIS IN TRAINED
THE ANGLE OF ELECTRICAL CARDIAC AXIS IN TRAINED

... The overall weight of heart as well as the size of its individual ventricles are the factors determining the heart shape, its location and the angle of anatomical cardiac axis. It is well known that there are significant variations of this value not only in different species and in different individ ...
How are arrhythmias managed in the paediatric population in
How are arrhythmias managed in the paediatric population in

... centres and collaborations with paediatric cardiologists and arrhythmologists. Even though some genetic diseases are associated with high mortality in the early years,4 – 6 the proportion of centres that would use genetic screening for channelopathies or suspected genetic disease was relatively low ...
Pulsus paradoxus - European Respiratory Journal
Pulsus paradoxus - European Respiratory Journal

... the  left  ventricle  must  eject  blood  toward  the  extrathoracic  arteries,  it  must  generate  a  higher  pressure  ‐  i.e.  transmural  pressure  ‐  before  blood  can  leave  the  thorax.  In  other  words, lowering ITP would be equivalent to raising the arterial pressure by a similar amoun ...
Cardiovascular Pharmacology
Cardiovascular Pharmacology

... Many SVTs are due to extra, abnormal electrical connections between the atria and the ventricles. Individuals with SVT are often born with these extra pathways. The existence of such extra pathways (often called “bypass tracts”) allow the formation of “reentrant” arrhythmias, in which an electrical ...
AORTIC VALVE STENOSIS: FROM FORMULA TO GUIDELINE
AORTIC VALVE STENOSIS: FROM FORMULA TO GUIDELINE

... Aortic valve stenosis is one of the most common valvular diseases and is the third most common cardiovascular disease in developed countries with an exponential age-dependent increase in prevalence. Severe AS occurs in about 2.8% of patients ≥75 years of age and can arise because of degenerative cal ...
Arginine Vasopressin Levels Are Elevated and
Arginine Vasopressin Levels Are Elevated and

... Mechanisms of Release The mechanism responsible for increased AVP levels in both types of CHF is not obvious. In fact, it is likely that multiple factors affect the release of AVP in these populations. We speculate that diminished systemic blood flow in these children may stimulate stretch receptors ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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