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Pulse pressure response to the strain of the Valsalva maneuver in
Pulse pressure response to the strain of the Valsalva maneuver in

... During the Valsalva maneuver, maximum (phase I) aortic pulse pressure ranged from 20 to 112 mmHg (mean 6 SD 5 58 6 24 mmHg), and minimum (phase II) aortic pulse pressure ranged from 12 to 31 mmHg (22 6 5 mmHg). This resulted in an aortic pulse amplitude ratio (minimum/maximum aortic pulse pressure) ...
Case Report Septic coronary embolism
Case Report Septic coronary embolism

... nfective endocarditis refers to conditions in which structures of the heart, most frequently the valves, harbor an infective process that leads to valvular dysfunction, localized or generalized sepsis, or sites for embolism [1]. The embolic events in infective endocarditis have a high prevalence, ra ...
Invasive Hemodynamic Monitoring
Invasive Hemodynamic Monitoring

... tissues. Under certain physiological conditions, which can range from illness to exercise, the normal heart should compensate to meet the demands placed upon it. ...
Systematization and clinical study of `dextroversion, mirror
Systematization and clinical study of `dextroversion, mirror

... ; Current embryological and anatomical knowledge makes it possible to systematize, classify, and diagnose the malpositions of the heart by following a logical sequence. (i) The visceral situs is easily established by means of data provided by physical, radiological, and electrocardiographic studies. ...
Right ventricular assist device in end
Right ventricular assist device in end

... Background: The high mortality rate of pulmonary arterial hypertension (PAH) mainly relates to progressive right ventricular (RV) failure. With limited efficacy of medical therapies, mechanical circulatory support for the RV has been considered. However, there is lack of understanding of the hemodyn ...
ESC Guidelines for the management of grown
ESC Guidelines for the management of grown

... involved in the Task Force, and was submitted to outside specialists for review. The document was revised, and finally approved by and subsequently published in the European Heart Journal. After publication, dissemination of the message is of paramount importance. Pocket-sized versions and personal ...
Aortic regurgitation due to quadricuspid aortic valve
Aortic regurgitation due to quadricuspid aortic valve

... By integrating all the data presented above, we observe that most cases of quadricuspid aortic valve are diagnosed by echocardiography (51%), followed by surgery (22.6%), necropsy (15.6%) and aortography (6,5%) (2). From a therapeutic point of view, surgical replacement of the quadricuspid aortic va ...
myocardial infarction - THRUTH ALWAYS SATISFY U ( Adeeb ul
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ECG Screening in Athletes: How does the Seattle Criteria Help?
ECG Screening in Athletes: How does the Seattle Criteria Help?

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PPT
PPT

... • Potential complications include, but are not limited to, valve damage, fibrillation and other arrhythmias, thrombosis, thrombotic and air embolism, cardiac perforation, heart wall rupture, cardiac tamponade, muscle or nerve stimulation, pericardial rub, infection, myocardial irritability, and pneu ...
Inherited heart conditions Hypertrophic cardiomyopathy
Inherited heart conditions Hypertrophic cardiomyopathy

... caused by a change or mutation in one or more genes. About 1 in 500 of the UK population1 has the condition, although most people who have it have few if any symptoms. We explain more about how cardiomyopathy is inherited on page 29 . Hypertrophic cardiomyopathy was first recognised more than a cent ...
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The right ventricle, outflow tract, and ventricular

... restricted to the anterior heart field and its derivatives. These mice will be a crucial tool for examining the genetic pathways that control cardiac development by conditional gene inactivation exclusively in the anterior heart field and its derivatives in the outflow tract and right ventricle. Mat ...
Detection of Trabeculae and Papillary Muscles in Cardiac MR Images
Detection of Trabeculae and Papillary Muscles in Cardiac MR Images

... imagery. Until recently, MR images did not provide sufficient detail to perform these measures, but with the increasing quality of the acquisition it becomes possible to segment these small structures. In this section, first a description is given of the anatomy of the papillary muscles and the trab ...
Myocardial cytokine gene expression is higher in aortic
Myocardial cytokine gene expression is higher in aortic

... there was a strong inverse relation between circulating TNFa and TNFa gene expression (r = 20.685, p = 0.014), between circulating TNFa and IL-1b gene expression (r = 20.664, p = 0.018), and between soluble TNF receptor 2 and TNFa gene expression (r = 20.685, p = 0.020). Myocardial gene expression o ...
Relation between myocardial infarct location and stroke
Relation between myocardial infarct location and stroke

... myocardial infarction, thrombus and stroke differ in methstudy oatients, timing of echocardiog~aphy~there including thrombolytic agents) and follow-up. e limitations in mind, pooling these studies shows that the likelihood of thrombus and embolizationin patients with anterior infarction is high whet ...
Print this article
Print this article

... volume overload [15-18]. Transesophageal echocardiography (TEE) may be performed for a more precise evaluation and sizing of the defect as well as magnetic resonance and/or cardiac catheterization in some cases. Medical treatment of a significant ASD with right ventricle volume overload should be ac ...


... unwillingness to have an MRI scan. The characteristics of patients who participated did not differ from those who declined with regard to age, gender, anthracycline dose, and previous chest irradiation as shown in Table 1. There were 3 patients who had previous acute cardiotoxicity as evidenced by d ...
Marfan Syndrome Guide
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Biventricular and atrial diastolic function assessment using
Biventricular and atrial diastolic function assessment using

... cardiac function. All participants were in sinus rhythm and demonstrated no abnormalities on a 12 lead surface ECG. A full clinical and echocardiographic examination was performed on each subject. No subjects had more than mild valvular disease. Twenty-two of the MFS patients were on b-blockade medi ...
opinions and hypotheses
opinions and hypotheses

... in a preoperative study that the benefit of biventricular pacing was in part due to improved atrioventricular synchrony and in part to ventricular resynchronization. Follow-up observations showed a sustained improvement that depended on correct function of the LV lead. Since this report, a substanti ...
2015-06-20 BMB cardiac sarcoidosis, manuscript
2015-06-20 BMB cardiac sarcoidosis, manuscript

... used for diagnosis and monitoring of cardiac sarcoidosis are presented in table 3 and an example of their use in a patient with biopsy proven sarcoidosis is shown in figure 6. The diagnostic algorithm used in our own institution is presented in figure 7. Comparison of PET with other imaging modaliti ...
Relative Contributions of the Atrial Systole
Relative Contributions of the Atrial Systole

... When the As-Vs interval during sequential atrioventricular pacing was adjusted to more closely approximate the prevailing As-Vs interval during atrial pacing, the difference in left ventricular end-diastolic pressure and circumference and mean left atrial pressure between these two types of pacing w ...
Microalbuminuria in systolic and diastolic chronic heart failure patients
Microalbuminuria in systolic and diastolic chronic heart failure patients

... Systolic ventricular dysfunction was diagnosed when the left ventricle ejection fraction (LVEF) was £ 45% and/or shortening fraction was £ 28%, and severe left ventricle wall movement abnormalities or dilatation of the left ventricle (end diastolic left ventricular diameter ≥ 55 mm) were present. Di ...
Jugular Venous Pulse: Window into the Right Heart
Jugular Venous Pulse: Window into the Right Heart

... angles of positioning, the average distance varied between 8 and 10 cm.23 Therefore, adding 5 cm H20 to the vertical distance measured on physical examination may be an accurate estimation of jugular venous pressure for patients in the supine position; however, when the head is elevated, this method ...
Electrical coupling of fibroblasts and myocytes: relevance for cardiac
Electrical coupling of fibroblasts and myocytes: relevance for cardiac

... Recipient-to-donor heart electrical coupling is observed after about 10% of heart transplantation cases [20]. This conduction pathway must cross scar tissue. Scars are, of course, neither static nor dead tissue [21], but in the absence of cardiomyocyte proliferation in adult heart, coupling across c ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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