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... muscle and are a substrate for re-entry ventricular arrhythmias. ...
The heart is responsible for generating the pressure that propels
The heart is responsible for generating the pressure that propels

... rest, both parasympathetic and sympathetic neurons are releasing neurotransmitters onto the heart, but the parasympathetic branch is dominant. During stress, exercise, and excessive heat the sympathetic influence is dominant. Hormones such as epinephrine (released by the adrenal medulla), thyroxine ...
Circulatory System
Circulatory System

... Intrinsic Control of Heartbeat *not under conscious control – it is involuntary and automatic Nodal Tissue: nerve/muscle characteristics ...
Adult Echocardoigraphy. Lecture 9 Valvular Heart Disease
Adult Echocardoigraphy. Lecture 9 Valvular Heart Disease

... fluttering of the mitral valve leaflets (mostly anterior) or ...
Genetic Testing to Detect Atrial Septal Defect with Atrioventricular
Genetic Testing to Detect Atrial Septal Defect with Atrioventricular

... position and size of the heart and the major blood vessels. A diagnosis can be confirmed by tests such as a chest X-ray or a heart MRI. However, the absence of these signs does not guarantee that no ASD is present. In addition, these signs may simply be missed during routine physical exams. About ha ...
Echocardiological Assessment of Diastolic Dysfunction using the Vevo
Echocardiological Assessment of Diastolic Dysfunction using the Vevo

... animal imaging and are ideally suited for mouse or rat echocardiography, as well as for studying the developing chick embryo. With center operating frequencies ranging from 15MHz to 50MHz one imaging system can be used to assess cardiac function from embryo to adult in many commonly used small anima ...
Left Ventricular Failure
Left Ventricular Failure

... to contractility, which is decreased in ventricular failure. Marvin's stroke volume was only 0.35 (35%) compared with the normal value of 0.55 (55%). 4. Pulmonary capillary wedge pressure is an estimate of left atrial pressure. It is measured by advancing a cannula through the pulmonary artery until ...
Heart failure
Heart failure

... NYHA Classification of HF Class I —No limitation: Ordinary physical activity does not cause undue fatigue, dyspnea, or palpitation. Class II —Slight limitation of physical activity: Such patients are comfortable at rest.Ordinary physical activity results in fatigue, palpitation dyspnea, or angina. ...
Factors that control the stroke volume are divided into: 1
Factors that control the stroke volume are divided into: 1

... As the afterload is increasing, the SV will be decreased, and that's why hypertension is a dangerous condition. So in a hypertensive patient who has a diastolic pressure (120 mmHg), the left ventricle must develop a pressure equal to or higher than 120 which is too high. In such a case, the heart de ...
Arrythmias presentation by Prof Celia Marr
Arrythmias presentation by Prof Celia Marr

... Clinical management of tachydysrhythmias ...
cardiac arrest and ventricular fibrillation
cardiac arrest and ventricular fibrillation

... An electroencephalogram was within normal limits. Twenty-two days after operation screening showed no evidence of aneurysm of the ventricles and movement of the ventricular borders was normal. ...
CARDIAC RESYNCHRONISATION THERAPY IN HEART FAILURE
CARDIAC RESYNCHRONISATION THERAPY IN HEART FAILURE

... to CRT respectively were sudden deaths that could have been avoided by associating a defibrillator back-up. Finally, results of the CARE-HF and COMPANION trials and those from another important meta-analysis (9) were consistent in showing a similar risk reduction for the combined end-point – hospita ...
Valvular Heart Disease and Postoperative Considerations
Valvular Heart Disease and Postoperative Considerations

... overload. Also, if the patient has pulmonary artery hypertension or coexisting right ventricular (RV) failure, the pulmonary artery diastolic pressure and/or central venous pressure, will have a higher baseline. Again, these indices do not necessarily represent fluid overload. If there is tricuspid ...
Dissecrtion of sheep Heart - Sinoe Medical Association
Dissecrtion of sheep Heart - Sinoe Medical Association

... The aorta is clearly visible at  the top, with an atrium on  either side while the either side, while the  ventricles are in the  bottom left. ...
Cardiovascular System: The Heart A
Cardiovascular System: The Heart A

... The short axis view is a plane perpendicular to a line from the apex of the heart along the interventricular septum to the approximate middle of the base of the heart. “This short axis slice of the specimen beautifully shows the annulus of the mitral valve. Additionally, the left circumflex artery c ...
Takotsubo Cardiomyopathy
Takotsubo Cardiomyopathy

... treatment might be considered in elderly women who have suffered an episode of takotsubo cardiomyopathy clinical trials of estrogen administration in takotsubo cardiomyopathy patients have not been performed. ...
Chapter 21: Blood Vessels and Circulation
Chapter 21: Blood Vessels and Circulation

... Cardiovascular Pathology • Coronary artery disease (CAD) – = Areas of partial or complete blockage of coronary circulation (usually arteries)  coronary ischemia (reduced blood supply to heart) – Causes • Formation of fatty plaque in wall of vessel • Thrombus (clot) • Spasm of smooth muscle in wall ...
ch18a_wcr
ch18a_wcr

... The short axis view is a plane perpendicular to a line from the apex of the heart along the interventricular septum to the approximate middle of the base of the heart. “This short axis slice of the specimen beautifully shows the annulus of the mitral valve. Additionally, the left circumflex artery c ...
Exploration of the Cause of the Low Intensity Aortic Component of
Exploration of the Cause of the Low Intensity Aortic Component of

... SUMMARY This investigation was undertaken to explore the cause of the diminished second sound (S2) that may occur in normotensive patients with poorly performing ventricles. Intraaortic sound and pressure were measured in 16 patients with angina; eight had normal ventricular performance (ejection fr ...
Heart rate
Heart rate

... – Coronary atherosclerosis – Persistent high blood pressure – Multiple myocardial infarcts ...
INNOVATIVE TECHNIQUES EXPERT COMMENTARY
INNOVATIVE TECHNIQUES EXPERT COMMENTARY

... bring improved patient outcomes, safety, and efficiency through the technology of robotics. One of the leading robotic technologies is remote magnetic catheter navigation technology (RMT). Recent medical literature contains a number of case reports and series demonstrating the feasibility of this te ...
Screening for left ventricular systolic dysfunction among patients
Screening for left ventricular systolic dysfunction among patients

... General medicine patients ⱖ60 years of age with hypertension, diabetes, coronary artery disease, or previous myocardial infarction (MI) but no history of HF or reduced left ventricular ejection fraction (LVEF) were eligible. Medical history and symptoms of breathlessness were determined by interview ...
Impaired aortic distensibility predicts reduced coronary flow velocity
Impaired aortic distensibility predicts reduced coronary flow velocity

... dimensions and blood pressures (as aortic elastic modulus) Peterson LN et al. Circ Res 1960 ...
Assessment of the stability of N-terminal pro-brain
Assessment of the stability of N-terminal pro-brain

... Plasma concentrations of N-terminal pro-brain natriuretic peptide (NT-proBNP) are raised in patients with left ventricular dysfunction. Measurement of this peptide has a potential diagnostic role in the identification and assessment of patients with heart failure. The stability of this peptide over ...
CVS - Notes For ANZCA Primary Exam
CVS - Notes For ANZCA Primary Exam

... Bainbridge reflex: opposite to baroreceptor reflex. Infusion of volume tends to increase heart rate when heart rate is slow/blood volume is high. The opposite may occur if initial HR is higher - however, according to Ganong this may be "competition" with the baroreceptor reflex ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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