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XStrain™ 4D
XStrain™ 4D

... Recently, 3D STE has been introduced by applying Speckle-tracking technologies to 3D echocardiographic images. Images are acquired using a matrix-array transducer, from the apical position in a wide-angled acquisition ‘‘full-volume’’ mode. In this mode, a number of wedge-shaped sub-volumes are acqui ...
Infective endocarditis - Oxford Academic
Infective endocarditis - Oxford Academic

... In 1885, William Osler presented the first comprehensive description of endocarditis. Thereafter, the descriptions of clinical features of IE were largely based on data obtained several decades ago. Nowadays, Oslerian peripheral stigmata of IE such as Osler’s nodes (3%) or Janeway lesions (5%) are u ...
Print this article - International Cardiovascular Forum Journal
Print this article - International Cardiovascular Forum Journal

... swimming. We report on three patients with unique presentations of IPE with associated development of Takotsubo cardiomyopathy (TTC). All three cases occurred in Oahu, Hawaii and were seen by the same cardiologist within a span of seven years. Each patient was scuba diving with sudden onset dyspnea ...
2/09 Transpostion of the Great Arteries
2/09 Transpostion of the Great Arteries

...  Treatment of systemic ventricular dysfunction is challenging: - No convincing data of utility of ACE-inhibitors - Caution with the use of beta-blockers (AVB, bradycardia) - Two-stage repair surgery (pulmonary artery banding to “retrain” the LV, followed by baffle take-down and arterial switch) is ...
FUNCTIONAL MITRAL REGURGITATION: IF THE MYOCARDIUM IS
FUNCTIONAL MITRAL REGURGITATION: IF THE MYOCARDIUM IS

... mediated by transforming growth factor beta expression, with consequent abnormal matrix composition, increased collagen concentration, and activation of valvular interstitial cells.9 This also represents a challenge during the diagnostic process: to distinguish secondary compensatory modifications f ...
Pathology N.47 Diseases of the heart part 1
Pathology N.47 Diseases of the heart part 1

... syndromes resulting from an imbalance between the supply and demand of the heart for oxygenated blood. Depending on the rate of development of arterial narrowing(s) and its ...
1. RIGHT CORONARY 2. LEFT ANTERIOR DESCENDING 3. LEFT
1. RIGHT CORONARY 2. LEFT ANTERIOR DESCENDING 3. LEFT

... supply of oxygen and nutrients. The coronary arteries are the network of blood vessels that carry oxygen- and nutrient-rich blood to the cardiac muscle tissue. The blood leaving the left ventricle exits through the aorta, the body’s main artery. Two coronary arteries, referred to as the "left" and " ...
The inoperable valvular heart disease patient
The inoperable valvular heart disease patient

... well as haemodynamic data. With the onset of symptoms, however, life expectancy is less than 2-3 years. When presented with symptomatic severe aortic stenosis in a high-risk patient, consideration for BAV is reasonable14. Many of these patients have low contractile reserve, which predicts high opera ...
BRS Physiology
BRS Physiology

... increased by changes that increase Pc or decrease πc. Arteriolar constriction would decrease Pc and decrease filtration. Dehydration would increase plasma protein concentration (by hemoconcentration) and thereby increase πc and decrease filtration. Increased venous pressure would increase Pc and fil ...
Use of Contrast Echocardiography for Evaluation of
Use of Contrast Echocardiography for Evaluation of

... of these patterns in allowing estimation of right ventricular pressure and resistance to ejection of blood from the right ventricle (RV) was investigated. Forty-four patients underwent 46 contrast echocardiographic procedures, all within 24 hours before cardiac catheterization. All patients were pla ...
Hypertensive Vascular Disease
Hypertensive Vascular Disease

... pressure overload hypertrophy  Initially without ventricular ...
Exercise-Induced Left Ventricular Systolic Dysfunction in Women
Exercise-Induced Left Ventricular Systolic Dysfunction in Women

... aimed at avoiding overt end-stage heart failure. Screening may consist of routine clinical examination only or may also include electrocardiography and possibly routine two-dimensional echocardiography. However, this approach can suffer from limited sensitivity.15 It is known that some women heteroz ...
Haemodynamics of pericardial diseases
Haemodynamics of pericardial diseases

... declines slightly less than does pleural pressure. As a result, pressure in the pulmonary veins (which are intrapleural but extrapericardial) declines more than left heart pressure, which results in impaired left heart filling due to the smaller filling pressure gradient . Blood therefore pools in t ...
Atraumatie Right Ventricular Aneurysm
Atraumatie Right Ventricular Aneurysm

... pathophysiological consequences of such aneurysms have been defined by hemodynamic and cinefluorographic studies both before and after successful resection.5-8 In contrast, aneurysms of the right ventricle are rare and coronary artery disease is not thought to be an important etiological factor. The ...
Heart Anatomy
Heart Anatomy

... branches penetrate the heart muscle. The smallest branches, called capillaries, are so narrow that the red blood cells must travel in single file. In the capillaries, the red blood cells provide oxygen and nutrients to the cardiac muscle tissue and bond with carbon dioxide and other metabolic waste ...
Boxer dog cardiomyopathy: an update
Boxer dog cardiomyopathy: an update

... is strongly suggestive of a diagnosis of ARVC, particularly if there is significant complexity (couplets, triplets, bigeminy, or ventricular tachycardia) to the arrhythmia. Alternatively, a strong suspicion of ARVC sometimes exists but the Holter monitor reading is not clearly abnormal. This may be b ...
Journal of the Hoffman - Saint Francis Hospital and Medical Center
Journal of the Hoffman - Saint Francis Hospital and Medical Center

... treatment begun. A positive study from one patient is shown at right. In the patients with negative findings, therapy was altered after TEE. Two showed good left ventricular (LV) function off of LV assist devices, and one was stable with a decrease of pressors, and was allowed to wean off uneventful ...
Arrhythmogenic Cardiomyopathy Panel Up to 23 genes
Arrhythmogenic Cardiomyopathy Panel Up to 23 genes

... that includes genes related to cardiomyopathy conditions with prominent arrhythmias. This test can be used to confirm a clinical diagnosis or identify at-risk individuals. Disorders of the heart can include abnormalities of the heart muscle (cardiomyopathies), irregularities of the heart’s electrica ...
INCREASING THE SURVIVAL CHANCE:
INCREASING THE SURVIVAL CHANCE:

... An AED is used to treat cardiac arrest. It is a life-saving device because cardiac arrest is a sudden condition that is fatal if not treated within a few minutes. Heart attacks and other conditions can cause ventricular fibrillation. In ventricular fibrillation, the electrical signals in the lower p ...
PDF - Circulation
PDF - Circulation

... is mitral regurgitation secondary to papillary muscle dysfunction or rupture or ventricular septal defect. 14 The diagnosis can be established at the bedside with the passage of a Swan-Ganz flowdirected catheter.'5' Oxygen samples from the right atrium, pulmonary artery, and radial artery will ident ...
Subpulmonary Obstruction Due to Aneurysmal Ventricular Septum
Subpulmonary Obstruction Due to Aneurysmal Ventricular Septum

... Extensive study of the atrioventricular conduction system in corrected transposition with situs solitus patients by several investigators11,16 determined that it is abnormally positioned, coursing in the anterior aspect of the subpulmonary tissue and along the anterior rim of the ventricular septal ...
Practical Electrocardiography: Diagnosis, Interpretation and
Practical Electrocardiography: Diagnosis, Interpretation and

... potassium should always be evaluated. The permanent form of atrial standstill is typically due to an atrial cardiomyopathy, and atrial enlargement should be observed on the echocardiogram and possibly on the radiographs. Treatment: In the case of the transient form, treat the hyperkalemia and identi ...
A Stoke from the Bishop`s Cap
A Stoke from the Bishop`s Cap

...  95% of these are Sarcomas (2nd to myxoma in overall frequency)  5% are Lymphomas  Sarcomas derive from mesenchyme, therefore have a wide variety of morphological types  Mutations in K-ras were seen in most cardiac sarcomas  Any age, but most common third and fifth decades  Except for rhabdomy ...
The Large Aortopulmonary Window Without
The Large Aortopulmonary Window Without

... recommendation that aortopulmonary septal defects have to be closed as soon as the diagnosis is established regardless of the age of the patient. This may require emergency surgical repair in the first week of life (7). Although in our patient APW was detected when he was four years old, he was oper ...
this PDF file
this PDF file

... muscle and are a substrate for re-entry ventricular arrhythmias. ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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