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Impaired aortic distensibility predicts reduced coronary flow velocity
Impaired aortic distensibility predicts reduced coronary flow velocity

... dimensions and blood pressures (as aortic elastic modulus) Peterson LN et al. Circ Res 1960 ...
Extraembryonic blood vessels form during the early
Extraembryonic blood vessels form during the early

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the role of heart sounds recording

... an increased risk of hospitalization and death compared to those patients without a detectable S3.11-13 (Table 1) Furthermore, in patients with decreased ventricular compliance (i.e. heart failure) a greater proportion of filling occurs in late diastole. As a result, the atrial component of ventricu ...
Implantable Cardioverter Defibrillator
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... (LVEF) even when no cardiac arrhythmias have been noted. Approximately one third of patients who receive ICDs are also candidates for cardiac resynchronization therapy (CRT) because of congestive heart failure (CHF) and an abnormally wide QRS. CRT typically requires three leads, one each to pace the ...


... methods for the assessment of diastolic function has improved our understanding of this complex entity. Standard indices of transmitral flow are hampered by their dependency on loading conditions and left ventricular (LV) relaxation and have therefore been unable to differentiate a patient with norm ...
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Consider Medtronic`s Intuitive Heart Valve Solutions

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The Right Ventricle of the Elite High End Endurance Athlete Cannot

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New cardiac magnetic resonance imaging modalities aid in the

... echocardiography or CMR. Various CMR sequences and contrast-enhanced imaging methods have more recently been adopted in clinical cardiology for their ability to provide detailed data on cardiac function, morphology, and perfusion. More commonly used for assessments of cardiac diseases, T2-weighted C ...
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"Broken Heart" Syndrome - Hellenic Journal of Cardiology

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Chronic Valvular Disease in the Dog

... developed. (The author falls into the latter group.) ● Two prospective double-blinded, placebo-controlled studies examined the hypothesis that angiotensin-converting enzyme (ACE) inhibitors would slow the development of heart failure.5,6 Neither study convincingly demonstrated a significant differen ...
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BRS Physiology Cases and Problems 2nd Edition

... filled from the atrium) is contracting. Contraction causes a steep increase in ventricular pressure. However, because the aortic valve is closed, no blood is ejected and left ventricular volume remains constant (i.e., is isovolumetric). 2 —> 3 is ventricular ejection. The ventricle is still contract ...
detailed lecture outline
detailed lecture outline

... ventricles rises, AV valves shut. 5. Ventricular ejection: Semilunar valves open, blood flows into pulmonary and aortic trunks. Stroke volume (SV) = 60% of end-diastolic volume. 6. Ventricular pressure falls, semilunar valves close. Ventricles contain endsystolic volume (ESV), about 40% of end-diast ...
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Fluid Balance in CHF Patients

... be a result of this damage. • Ventricular remodeling of the myocardium can result in heart failure because the ventricular cannot pump blood efficiently. ...
The Circulatory System:
The Circulatory System:

... • Know basic heart anatomy • Understand what the cardiac conduction system is and how it works • Understand pacemaker physiology and how this influences myocardial electrical activity • Know what an ECG is and be able to interpret it • Know what the cardiac cycle is and how cardiac output ...
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Assessment of a right ventricular metastasis using contrast

... carcinoma with multiple metastases, including cardiac involvement discovered at echocardiography and further characterized by contrast echo perfusion imaging. ...
valvular heart disease and risk score systems in clinical practice
valvular heart disease and risk score systems in clinical practice

... disease, mainly represented by calcific aortic stenosis in the elderly. In developing countries, valvular heart disease triggered by rheumatic fever is the most important aetiology and can lead to a heterogeneous heart valve disease, mainly represented by mitral stenosis in young female patients. Th ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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