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Matrix Metalloproteinases and Their Tissue Inhibitors in Cardiac
Matrix Metalloproteinases and Their Tissue Inhibitors in Cardiac

... Amyloid cardiomyopathy due to immunoglobulin light chain protein (AL-CMP) deposition has an accelerated clinical course and a worse prognosis compared with non–light chain cardiac amyloidoses (ie, forms associated with wild-type or mutated transthyretin [TTR]). We therefore tested the hypothesis tha ...
Interventions for Clients with Dysrhythmias
Interventions for Clients with Dysrhythmias

... fatigue, weakness, shortness of breath, distended neck veins, dizziness, decreased exercise tolerance, anxiety, syncope, palpitations, chest discomfort or pain, and hypotension. The client is also at risk for pulmonary embolism. The nurse should assess for shortness of breath, chest pain, hemoptysis ...
Clinical applications of cardiovascular magnetic resonance imaging
Clinical applications of cardiovascular magnetic resonance imaging

... Arrhythmogenic RV cardiomyopathy is characterized by progressive fibro-fatty replacement involving variable regions of the right and left ventricles. Often the first manifestation is ventricular tachycardia or fibrillation in a young patient. Cardiovascular MRI is useful for diagnosing the condition ...
Peak cardiac power output and cardiac reserve in sedentary men
Peak cardiac power output and cardiac reserve in sedentary men

... capacity of the heart can be obtained. This study provides values of cardiac power output at rest and peak exercise in healthy sedentary women and men in our population. Participants were considered sedentary if they were not involved in any organized physical activity in last 12 months. Mayor findi ...
Beta-blockers for the prevention of sudden cardiac death in heart
Beta-blockers for the prevention of sudden cardiac death in heart

... Background: In many studies, beta-blockers have been shown to decrease sudden cardiac death (SCD) in heart failure patients; other studies reported mixed results. Recently, several large randomized control trials of beta blockers have been carried out. It became necessary to conduct a systematic rev ...
Single and Dual Chamber Pacemaker Timing Module 6 1
Single and Dual Chamber Pacemaker Timing Module 6 1

... • Potential complications include, but are not limited to, valve damage, fibrillation and other arrhythmias, thrombosis, thrombotic and air embolism, cardiac perforation, heart wall rupture, cardiac tamponade, muscle or nerve stimulation, pericardial rub, infection, myocardial irritability, and pneu ...
maternity and myocardial failure in african women
maternity and myocardial failure in african women

... failure; most often this syndrome followed apparently normal pregnancies. Because the diagnosis of toxwmia had usually to be made retrospectively, doubt about its frequency persists. THE CLINICAL PICTURE Symptoms. In most cases the onset is sub-acute or gradual; in a few, three in this series, it is ...
a PDF of this article. - Journal of Invasive Cardiology
a PDF of this article. - Journal of Invasive Cardiology

... Mustafa Kemal Erol, MD1, Ihsan Bakir, MD3 valve replacement. Not surprisingly, AV conduction disturbance can also occur with TAVI, presumably as a consequence of the pressure applied on the conducting tissues located subendocardially in the left ventricular (LV) outflow tract and interventricular se ...
Idiopathic fascicular left ventricular tachycardia: Linear
Idiopathic fascicular left ventricular tachycardia: Linear

... the VTs in some patients are noninducible or are only brief and characterized by nonsustained paroxysms that preclude detailed activation mapping. Pace mapping alone can be successful in some of these patients. However, the limitations of pace mapping and the difficulty in achieving a 12 of 12 ECG m ...
Catheter-based management of aortic valve
Catheter-based management of aortic valve

... Elementary physiology and pathophysiology of the aortic valve The left ventricle generates a pressure under which a certain amount of blood is transported behind the aortic valve. Ideally, none of the expelled volume returns behind the valve. Trace regurgitation, demonstrable solely using auxiliary ...
Effect of Age, Sex, and Body Surface Area
Effect of Age, Sex, and Body Surface Area

... first group included 136 subjects, 78 men and 58 women, without evidence of heart disease, who ranged in age from 20 to 97 years. None of the subjects had a history suggesting heart disease or hypertension, an abnormal electrocardiogram, or an abnormal chest x-ray. In addition, none of the subjects ...
Surgical removal of a large mobile left ventricular thrombus via left
Surgical removal of a large mobile left ventricular thrombus via left

... Ventriculotomy provides direct visualization of the thrombus; thus it has been considered the standard approach for complete removal of the thrombus. This may be best utilized for mural thrombus which is adhered to the ventricular wall. However, LV ventriculotomy often causes further deterioration o ...
- Wiley Online Library
- Wiley Online Library

... 15219. E-mail: [email protected] ...
Influence of Right Ventricular Filling Pressure on Left Ventricular
Influence of Right Ventricular Filling Pressure on Left Ventricular

... The effects of alterations in the diastolic filling pressure of the right ventricle on left ventricular (LV) geometry and filling pressure were studied in six isolated, supported canine hearts. This experimental preparation permitted graded increments in right ventricular (RV) end-diastolic pressure ...
The Impact of Transcatheter Atrial Septal Defect Closure in the Older
The Impact of Transcatheter Atrial Septal Defect Closure in the Older

... Atrial septal defect (ASD) is one of the most common forms of congenital heart disease in adults (1), accounting for approximately 10% of all congenital cardiac defects (2,3). The left-toright shunt through an ASD results in chronic volume overload of the right heart and, if untreated, may lead to a ...
Adult Echocardiography Protocol Patient Position For parasternal
Adult Echocardiography Protocol Patient Position For parasternal

... Acquire cine loop of 2D image of left ventricle at level of the papillary muscles Papillary muscles Apex of LV Acquire cine loop of 2D image of left ventricle apex ...
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... of PAH. The PAH group had a significantly reduced TAPSE and S´ at rest and demonstrated markedly attenuated contractile reserve, as measured by TAPSE and S´, compared with controls. Intriguingly, there was a subset of PAH patients with relatively well preserved TAPSE (10 out of 16 had TAPSE ⩾1.6 cm) ...
Management of Valvular Heart Disease
Management of Valvular Heart Disease

... valvular heart disease and any of the following: – history of coronary artery disease – suspected myocardial ischaemia (Chest pain, abnormal non-invasive testing) – left ventricular systolic dysfunction – in men aged over 40 and post-menopausal women – ≥ 1 cardiovascular risk factor ...
General Heart Failure
General Heart Failure

... Frequency of signs and symptoms Clinical manifestations of chronic heart failure Signs and symptoms in a small study conducted by two cardiac outpatient centers from the US ...
EKG
EKG

... This is a block caused by the AV Node Every SA impulse is conducted but the length of AV conduction is prolonged Conduction is normal through the ventricles What you will see is: ...
General Heart Failure
General Heart Failure

... Frequency of signs and symptoms Clinical manifestations of chronic heart failure Signs and symptoms in a small study conducted by two cardiac outpatient centers from the US ...
Sudden cardiac death in young athletes: what is the role
Sudden cardiac death in young athletes: what is the role

... study of 115 cases of SCD, only one case (0.9%) was identified using history and physical examination [29]. Similarly, low sensitivity can be found in other US and international studies in which a history and physical examination appropriately detected an underlying abnormality in 0–33% of cases ide ...
Assessment of Cardiac Murmurs in Children
Assessment of Cardiac Murmurs in Children

... should be treated as any normal child. Special precautions are unnecessary, and participation in physical activities is encouraged as it confers no additional risks. From the family doctor's point of view, the diagnosis of an innocent murmur can sometimes be made confidently after a thorough histor ...
ECG-gated multidetector-row computed tomography in the
ECG-gated multidetector-row computed tomography in the

... The evaluation of cardiac function can provide important diagnostic and prognostic information in many diseases that have an impact on the performance of the pump activity of the heart. The assessment of cardiac function, in an accurate and reproducible way, is crucial in determining the severity of ...
Long term survival study of patients with raised pulmonary arterial
Long term survival study of patients with raised pulmonary arterial

... since patients with these conditions are not routinely screened for PH. Pulmonary hypertension and therefore is under detected.[5] Pulmonary arterial systolic pressure (PASP) can be estimated with transthoracic echocardiography (TTE) by measuring the tricuspid regurgitant (TR) jet velocity. Echocard ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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