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Region-specific alterations of A-to-I RNA editing of
Region-specific alterations of A-to-I RNA editing of

... Region-specific alterations of A-to-I RNA editing of serotonin 2c receptor in the cortex of suicides with major depression D Weissmann1, S van der Laan1, MD Underwood2,3, N Salvetat1, L Cavarec4, L Vincent5, F Molina1, JJ Mann2,3, V Arango2,3 and JF Pujol1 Brain region-specific abnormalities in seroto ...
Jesús Pujol Martí  Neural map organization and development in the lateral-line system
Jesús Pujol Martí Neural map organization and development in the lateral-line system

... The nervous system has seized scientists‟ attention throughout the ages. Anatomical methods are the oldest way for studying the nervous system and have uncovered basic principles of its organization, defining a valuable groundwork for understanding its functions. Another important source of informat ...
Functional Anatomy, Physiology and Clinical Aspects of Basal Ganglia
Functional Anatomy, Physiology and Clinical Aspects of Basal Ganglia

... reticulata (which physiologically and anatomically constitute one structure) or via the ventral globus pallidus reach the thalamus and the cerebral cortex subsequently. The evidence of the anatomical and physiological brain research supported by clinical data and theoretical models suggests there ar ...
the evolution of body and brain, and of sensory
the evolution of body and brain, and of sensory

... and know how to get to distant places by the shortest and safest routes. They must also be knowledgeable about the seasonal ripening cycle of different varieties of fruits, and where to turn if some trees fail to bear their nutritious products (Tsuji and Takatsuki, 2009). Finally, since a ripe tree ...
The Physics of the Brain
The Physics of the Brain

... Where B is a normalization constant, and τ1 > τ2 is the fall time. Or the even simpler ‘alpha’ function: ...
View PDF - Laboratory of Brain, Hearing and Behavior
View PDF - Laboratory of Brain, Hearing and Behavior

... performance after focal SC inactivation of the representation of the target stimulus. Downward black arrow indicates the decreased performance caused by SC inactivation. From [16!!]. (b) Discriminability of the strongest (highest priority) stimulus by neuronal responses in the owl OT as a function o ...
Diversity of reporter expression patterns in transgenic mouse lines
Diversity of reporter expression patterns in transgenic mouse lines

... Validation of the anti-CRH serum and expression mice pattern of the peptide in adult mouse Because of the crucial role of hypothalamic CRH in We employed here the antihuman/rat CRH serum initiating the neuroendocrine response to stress, we fo(rC68) created by Dr. Wylie Vale (31). This antiserum has ...
Oxytocin Influence on the Nucleus of the Solitary Tract
Oxytocin Influence on the Nucleus of the Solitary Tract

... NTS neurons and heterogeneous innervation by oxytocin-containing axons projecting from the paraventricular nucleus. The study includes a brief, but interesting, discussion of how innervation of the NTS by oxytocin-synthesizing paraventricular nucleus neurons may modulate homeostatic reflexes; we pro ...
DOES ISCHEMIA CAUSE ACUTE NEURONAL DAMAGE BY CONVERTING THE NA /K
DOES ISCHEMIA CAUSE ACUTE NEURONAL DAMAGE BY CONVERTING THE NA /K

... al., 1981; Woodruff et al., 2011). The penumbra is the prime target of stroke therapeutics because it is potentially salvageable after the onset of stroke (Dirnagl et al., 1999). This may be achieved following timely reperfusion within 6-8 hours (Kaufmann et al., 1999). The brain injury and neurolog ...
Maruska & Tricas 2009b
Maruska & Tricas 2009b

... (80–800 Hz). These data were used to construct the isointensity response curves. Stimuli consisted of 100 repetitions of 40 ms ramped tone bursts (10 ms rise and fall; 20 ms plateau; 8.3 Hz repetition rate) at frequencies of 80–800 Hz (80, 100, 200, 300, 400, 500, 600, 800 Hz). The frequency respons ...
Lillienfeld: Chapter 3 lecture PowerPoint
Lillienfeld: Chapter 3 lecture PowerPoint

... Distinguish the parts of neurons and what they do. Describe electrical responses of neurons and what makes them possible. Explain how neurons use neurotransmitters to communicate with each other. Describe how the brain changes as a result of development, learning, and injury. Identify what roles dif ...
Signal processing methods in Sleep Research
Signal processing methods in Sleep Research

Emotion Dysregulation
Emotion Dysregulation

... are overly rigid, or fail, adolescents may exhibit behaviors associated with emotion dysregulation, including prolonged depressed mood, chronic anxiety, and risky behaviors. In order to define emotion dysregulation, it is first helpful to define emotion regulation. Although researchers do not agree ...
MECHANISMS OF VERTEBRATE SYNAPTOGENESIS
MECHANISMS OF VERTEBRATE SYNAPTOGENESIS

... from the ventral horn of the spinal cord delay synapse formation until they innervate muscle fibers some distance away (Burden 2002, Sanes & Lichtman 2001). In these examples not only is synapse formation delayed until axons reach specific target regions, but even within these target regions there are ...
Single Nigrostriatal Dopaminergic Neurons Form Widely Spread
Single Nigrostriatal Dopaminergic Neurons Form Widely Spread

Sample Chapter - Brookings Institution
Sample Chapter - Brookings Institution

... the players, coordinating their work, and ensuring that the result promotes the public interest. The power of networked government lies in its pragmatism. Its proponents begin with the assessment that most classical theories fall short in describing how public programs actually work, and they seek t ...
Tumor necrosis factor-alpha in normal and diseased brain
Tumor necrosis factor-alpha in normal and diseased brain

... From the 1 Center for Aging and Developmental Biology, Aab Biomedical Institute, and the Departments of 2 Neurology (Child Neurology Division), 3 Microbiology and Immunology, and 4 Pediatrics, and the 5 Interdepartmental Graduate Program in Neuroscience, University of Rochester Medical Center, Roche ...
Linking Objects to Actions: Encoding of Target Object and Grasping
Linking Objects to Actions: Encoding of Target Object and Grasping

... dimensionality reduction). Instead, the method relies on the intrinsic properties of the neural data and does not require an explicit model of the relationship between neural activity and external variables. The SSIMS algorithm begins by embedding the neural data into a high-dimensional pairwise sim ...
Dynamic shaping of dopamine signals during probabilistic
Dynamic shaping of dopamine signals during probabilistic

... Cue- and reward-evoked phasic dopamine activity during Pavlovian and operant conditioning paradigms is well correlated with reward-prediction errors from formal reinforcement learning models, which feature teaching signals in the form of discrepancies between actual and expected reward outcomes. Add ...
Activity of Defined Mushroom Body Output Neurons
Activity of Defined Mushroom Body Output Neurons

... 2014; Wang et al., 2014). The LH is largely believed to be responsible for driving innate behavioral responses to odors, since blocking all mushroom body neuron output has little consequence on these behaviors (Heimbeck et al., 2001; Parnas et al., 2013). In contrast, disrupting the mushroom body ha ...
Branched thalamic afferents - the Sherman Lab
Branched thalamic afferents - the Sherman Lab

... The patterns of axonal branching revealed by the Golgi method and described in significant detail by Cajal form the subject of this essay. They were early recognized as important. The Golgi method allowed investigators to trace axons for long distances, find branching points and often trace individu ...
Carlson (7e) PowerPoint Lecture Outline Chapter 9: Sleep and
Carlson (7e) PowerPoint Lecture Outline Chapter 9: Sleep and

... Sleep is noted in all vertebrates The signs of REM sleep (muscle paralysis, EEG desynchrony, eye movements) occur in mammals Did sleep evolve to keep our ancestors away from predators? Indus dolphins sleep even though doing so is dangerous u ...
Thalamocortical inputs trigger a propagating envelope of gamma
Thalamocortical inputs trigger a propagating envelope of gamma

... containing functionally linked thalamocortical and intracortical pathways. In extracellular recordings, stimulation of thalamic afferents elicited a short-latency field potential and current sink in layer IV of the cortex, followed by 100–500 ms of polysynaptic activity containing rapid (gamma-band, ...
Attention-Deficit Hyperactivity Disorder
Attention-Deficit Hyperactivity Disorder

... also smaller in ADHD children. The imaging findings make sense because the brain areas that are reduced in size in children with ADHD are the very ones that regulate attention. The right prefrontal cortex, for example, is involved in “editing” one’s behavior, resisting distractions and developing an ...
The Nervous System
The Nervous System

... a. helps control the functioning of most internal organs 3. controls hormone secretion by anterior and posterior pituitary glands a. indirectly helps control hormone secretion by most other endocrine glands 4. contains center for controlling appetite, wakefulness, pleasure, etc ii. structure and fun ...
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Metastability in the brain

In the field of computational neuroscience, the theory of metastability refers to the human brain’s ability to integrate several functional parts and to produce neural oscillations in a cooperative and coordinated manner, providing the basis for conscious activity.Metastability, a state in which signals (such as oscillatory waves) fall outside their natural equilibrium state but persist for an extended period of time, is a principle that describes the brain’s ability to make sense out of seemingly random environmental cues. In the past 25 years, interest in metastability and the underlying framework of nonlinear dynamics has been fueled by advancements in the methods by which computers model brain activity.
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