The Basal Ganglia and Motor Control
... motor and premotor areas of the cerebral cortex. In this way, both the basal ganglia and the cerebellum have an essential and distinctive role in the organization (coordination, timing, and sequencing) of a normal motor output. Finally, the basal ganglia, as well as the cerebellum, play an important ...
... motor and premotor areas of the cerebral cortex. In this way, both the basal ganglia and the cerebellum have an essential and distinctive role in the organization (coordination, timing, and sequencing) of a normal motor output. Finally, the basal ganglia, as well as the cerebellum, play an important ...
Late-onset Parkinsonism in NFjB/c-Rel
... tyrosine hydroxylase-immunoreactivity and Nissl staining. Nigral degeneration was accompanied by a significant loss of dopaminergic terminals and a significant reduction of dopamine and homovanillic acid levels in the striatum. Mice deficient of the c-Rel factor exhibited a marked immunoreactivity f ...
... tyrosine hydroxylase-immunoreactivity and Nissl staining. Nigral degeneration was accompanied by a significant loss of dopaminergic terminals and a significant reduction of dopamine and homovanillic acid levels in the striatum. Mice deficient of the c-Rel factor exhibited a marked immunoreactivity f ...
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... strategy approach to maximize reward and minimize costs; otherwise, competitive opponents can exploit predictable choice patterns. This thesis tested the hypothesis that the frontal eye field (FEF) are involved ...
... strategy approach to maximize reward and minimize costs; otherwise, competitive opponents can exploit predictable choice patterns. This thesis tested the hypothesis that the frontal eye field (FEF) are involved ...
Peripheral and Central Mechanisms of Pain Generation
... nerve or plexus damage, metabolic diseases such as diabetes mellitus, or herpes zoster. Damage to central neurons (e.g. in the thalamus) can cause central neuropathic pain. This relatively simple classification of pain will certainly be modified for several reasons. First, in many cases pain is not st ...
... nerve or plexus damage, metabolic diseases such as diabetes mellitus, or herpes zoster. Damage to central neurons (e.g. in the thalamus) can cause central neuropathic pain. This relatively simple classification of pain will certainly be modified for several reasons. First, in many cases pain is not st ...
Gao JCN 2000 - Georgia State University
... gion was analyzed quantitatively only in three cases where it was not clear that complete labeling had been obtained. Data from a previous study of Nissl-stained neurons, discussed here for comparison, included a total of 70 sections from the V1 of 53 ferrets, and 67 sections from AI of 55 ferrets ( ...
... gion was analyzed quantitatively only in three cases where it was not clear that complete labeling had been obtained. Data from a previous study of Nissl-stained neurons, discussed here for comparison, included a total of 70 sections from the V1 of 53 ferrets, and 67 sections from AI of 55 ferrets ( ...
Motor Cognition and Mental Simulation
... his reasoning processes relied on the kinds of logical deductions and inductions we discussed in Chapter 10? In fact, there is evidence that a different sort of cognition underlies our reasoning in action situations. Specifically, one way we reason is by forming and transforming mental images of pos ...
... his reasoning processes relied on the kinds of logical deductions and inductions we discussed in Chapter 10? In fact, there is evidence that a different sort of cognition underlies our reasoning in action situations. Specifically, one way we reason is by forming and transforming mental images of pos ...
PDE5 Exists in Human Neurons and is a Viable Therapeutic Target
... against the 3’UTR region (each primer shows the average for 3 samples; error bars are standard error). Values are normalized against -actin. B) PDE5 protein was detected in human cortex, hippocampus, and cerebellum by western blot, using two different antibodies to PDE5 (Cell Signaling and Atlas, s ...
... against the 3’UTR region (each primer shows the average for 3 samples; error bars are standard error). Values are normalized against -actin. B) PDE5 protein was detected in human cortex, hippocampus, and cerebellum by western blot, using two different antibodies to PDE5 (Cell Signaling and Atlas, s ...
Wide field-of-view, twin-region two-photon imaging across extended
... Conventional two-photon imaging is limited to narrow border regions that fail to cover significant portions of mouse cortical areas. By contrast, a expanded field-of-view (FOV) would cover more cortical area and enable investigations of activity in multiple cortical areas. (c) Raster scanning a larg ...
... Conventional two-photon imaging is limited to narrow border regions that fail to cover significant portions of mouse cortical areas. By contrast, a expanded field-of-view (FOV) would cover more cortical area and enable investigations of activity in multiple cortical areas. (c) Raster scanning a larg ...
Where do mirror neurons come from?
... However, the associative hypothesis currently has three advantages. First, it provides a straightforward, empirically testable explanation for the differences between monkeys and humans that have led some researchers to question the existence of a ‘mirror neuron system’. Second, it is consistent wit ...
... However, the associative hypothesis currently has three advantages. First, it provides a straightforward, empirically testable explanation for the differences between monkeys and humans that have led some researchers to question the existence of a ‘mirror neuron system’. Second, it is consistent wit ...
Role of Slitrk Family Members in
... genetic causes for certain mental illness have been identified. This thesis focuses on a novel family of proteins termed the Slitrks. Initial characterization of the Slitrk family genes revealed that their expression is enriched in the central nervous system. Herein, I have performed a detailed anal ...
... genetic causes for certain mental illness have been identified. This thesis focuses on a novel family of proteins termed the Slitrks. Initial characterization of the Slitrk family genes revealed that their expression is enriched in the central nervous system. Herein, I have performed a detailed anal ...
Grid Cell Mechanisms and Function: Contributions of Michael E. Hasselmo*
... model effectively simulates the two-dimensional firing of grid cells in open field environments, as well as the properties of theta phase precession. This model provides an alternate implementation of oscillatory interference models. The persistent firing could also interact on a circuit level with ...
... model effectively simulates the two-dimensional firing of grid cells in open field environments, as well as the properties of theta phase precession. This model provides an alternate implementation of oscillatory interference models. The persistent firing could also interact on a circuit level with ...
SIADH, DI and Cerebral Salt Wasting
... – Secreted in response to increased pressure or stretch – Similar effects to ANP – BNP levels are elevated in patients with SAH – Acute intracranial disease may cause release of cardiac BNP, and hypothalamic damage may also ...
... – Secreted in response to increased pressure or stretch – Similar effects to ANP – BNP levels are elevated in patients with SAH – Acute intracranial disease may cause release of cardiac BNP, and hypothalamic damage may also ...
CNS Distribution of Members of the Two-Pore
... accumulation was seen in the cerebellum and somatic motoneurons. TASK-3 was much more widely distributed, with robust expression in all brain regions, with particularly high expression in somatic motoneurons, cerebellar granule neuAs their name suggests, “leak” potassium (K ⫹) channels are K ⫹-selec ...
... accumulation was seen in the cerebellum and somatic motoneurons. TASK-3 was much more widely distributed, with robust expression in all brain regions, with particularly high expression in somatic motoneurons, cerebellar granule neuAs their name suggests, “leak” potassium (K ⫹) channels are K ⫹-selec ...
Estrogen Actions Throughout the Brain
... neurons, and the basal forebrain cholinergic system as well as the hippocampal formation, a brain region involved in spatial and declarative memory. Thus, ovarian steroids have measurable effects on affective state as well as cognition, with implications for dementia. Two actions are discussed in th ...
... neurons, and the basal forebrain cholinergic system as well as the hippocampal formation, a brain region involved in spatial and declarative memory. Thus, ovarian steroids have measurable effects on affective state as well as cognition, with implications for dementia. Two actions are discussed in th ...
Tactile orientation perception: an ideal observer analysis of human
... have elliptical RFs (Pruszynski and Johansson 2014; VegaBermudez and Johnson 1999) with aspect ratios that are similar, on average, to those of S1 cortical neurons (Sripati et al. 2006b). Elongated RFs, however, seem to be somewhat more prevalent in cortex than in the periphery. Sripati et al. (2006 ...
... have elliptical RFs (Pruszynski and Johansson 2014; VegaBermudez and Johnson 1999) with aspect ratios that are similar, on average, to those of S1 cortical neurons (Sripati et al. 2006b). Elongated RFs, however, seem to be somewhat more prevalent in cortex than in the periphery. Sripati et al. (2006 ...
Low-Dose Alcohol Consumption Protects against Transient Focal
... reduced PPARc protein in the nucleus. In addition to the nucleus, PPARc also expresses in the cytoplasm [22]. Thus, upregulated PPARc mRNA during reperfusion may be a compensatory response and increased PPARc immunoreactivity may be mainly located in the cytoplasm. Transient focal cerebral ischemia ...
... reduced PPARc protein in the nucleus. In addition to the nucleus, PPARc also expresses in the cytoplasm [22]. Thus, upregulated PPARc mRNA during reperfusion may be a compensatory response and increased PPARc immunoreactivity may be mainly located in the cytoplasm. Transient focal cerebral ischemia ...
Post-pubertal Emergence of Prefrontal Cortical Up
... Spontaneous plateau depolarizations were observed sporadically during baseline recordings. These events lasted 452.9 ± 122.2 ms and occurred about once every 12 min (0.0014 ± 0.0004 Hz, n = 16). Spontaneous depolarizations were not observed in slices from immature animals (PD < 40, n = 26). Because ...
... Spontaneous plateau depolarizations were observed sporadically during baseline recordings. These events lasted 452.9 ± 122.2 ms and occurred about once every 12 min (0.0014 ± 0.0004 Hz, n = 16). Spontaneous depolarizations were not observed in slices from immature animals (PD < 40, n = 26). Because ...
Neurally Plausible Model of Robot Reaching Inspired by Infant
... emphasizes the importance of the sensorimotor interaction of an agent and the world. It includes both learning sensorimotor correlations through motor babbling and also arm motion planning using spreading activation. We introduce a mechanism called bundle formation as a way to generalize motions dur ...
... emphasizes the importance of the sensorimotor interaction of an agent and the world. It includes both learning sensorimotor correlations through motor babbling and also arm motion planning using spreading activation. We introduce a mechanism called bundle formation as a way to generalize motions dur ...
Section and Senior Editor - HAL
... mouse was subjected to this test six times separated by an interval of 5-10 days, three times at 2 P.M. and three times at 6 P.M. (n = 39 from 13 pairs of mice, for both time parameters). To characterize the effects of the wheel test on the sleep-wake cycle and locomotion, a pretreatment was given t ...
... mouse was subjected to this test six times separated by an interval of 5-10 days, three times at 2 P.M. and three times at 6 P.M. (n = 39 from 13 pairs of mice, for both time parameters). To characterize the effects of the wheel test on the sleep-wake cycle and locomotion, a pretreatment was given t ...
Folie 1
... • Is not clear, because… …both can be context independent …both can be counted as having symbols …both can be localist or distributed ...
... • Is not clear, because… …both can be context independent …both can be counted as having symbols …both can be localist or distributed ...
The dorsal raphe nucleus—From silver stainings to a role in
... In their studies on the rat DRN, Dahlström and Fuxe used formaldehyde-induced fluorescence (FIF), which had been developed by Falck et al. (1962) for visualization of monoamines. The FIF-technique soon became the most popular tool for visualizing serotonergic neurons in the DRN and elsewhere. A majo ...
... In their studies on the rat DRN, Dahlström and Fuxe used formaldehyde-induced fluorescence (FIF), which had been developed by Falck et al. (1962) for visualization of monoamines. The FIF-technique soon became the most popular tool for visualizing serotonergic neurons in the DRN and elsewhere. A majo ...
lmmunocytochemical Localization of Protein Kinase C lsozymes in
... with tvne I and II PKC (Nakabavashi and Huane. 1988). resnectivelv. were used in the present‘study and were referred-to as MC-I-and MC: II. Indirect immunojluorescent staining. Frozen brains of adult SpragueDawley rats previously perfused with cold 4% paraformaldehyde in 120 mM phosphate buffer, pH ...
... with tvne I and II PKC (Nakabavashi and Huane. 1988). resnectivelv. were used in the present‘study and were referred-to as MC-I-and MC: II. Indirect immunojluorescent staining. Frozen brains of adult SpragueDawley rats previously perfused with cold 4% paraformaldehyde in 120 mM phosphate buffer, pH ...