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Neurodegenerative Changes in the Motor Cortex and Cerebellum in Wistar... Following Acute Pneumococcal Meningitis
Neurodegenerative Changes in the Motor Cortex and Cerebellum in Wistar... Following Acute Pneumococcal Meningitis

... cortex was counted at 400X magnification. The neurons with clear cell boundary and nucleus were only counted and cells with irregular shapes and that which stained darkly were excluded from quantification. A total of 15sections spaced 20 microns apart were selected for quantification. Number of neur ...
Biomimetic approaches to the control of underwater walking machines
Biomimetic approaches to the control of underwater walking machines

... 4. Neurobiology of lobster locomotion Studies over the past 50 years have demonstrated that the innate behaviour of animals is generated by the distributed networks of neurons in the central nervous system (Delcomyn 1980). Lobsters and crayfish served as important model systems in the development of ...
Neuronal responses to face-like and facial stimuli in the monkey
Neuronal responses to face-like and facial stimuli in the monkey

... Since it has been reported that individual sSC neurons are not sensitive to shape (Schiller and Koerner, 1971; Goldberg and Wurtz, 1972), we hypothesized that population activity of sSC neurons could better discriminate these prototypical facial stimuli than activity of individual sSC neurons. It is ...
Massively Parallel Recording of Unit and Local Field
Massively Parallel Recording of Unit and Local Field

... INTRODUCTION ...
Tracking the Emergence of Conceptual Knowledge during Human
Tracking the Emergence of Conceptual Knowledge during Human

... Supplemental Results). We first conducted an analysis designed to identify the overall brain network associated with proficient performance on learning trials. As a first step, we set out to convert participants’ binary performance data, where 1 indexed a correct response and 0 an incorrect response ...
Got diversity? Wiring the fly brain with Dscam
Got diversity? Wiring the fly brain with Dscam

... contrast, binding of ephrin ligands to eph receptors on growth cones often results in repulsion [10]. The notion that binding between proteins on opposing cell surfaces can promote repulsion might seem counterintuitive. In other words, how can two cells bound to each other be repelled from one anoth ...
Human Nervous System
Human Nervous System

... • The cranial nerves are arranged in 12 pairs, so the two nerves on a pair are identical in function and structure. • These nerves serve both sensory and motor functions. ...
Motor-iconicity of sign language does not alter the neural
Motor-iconicity of sign language does not alter the neural

... Grafton, 2002; Moll et al., 2000). These studies all used a complex, but non-meaningful, sequence of hand movements as the baseline against which tool-use pantomimes were compared. Thus, the superior parietal lobule (SPL) appears to play an important role in the production of meaningful gestures rel ...
Planarian shows decision-making behavior in response to multiple
Planarian shows decision-making behavior in response to multiple

... stimuli, its nervous system detects sensory cues and converts this information into adaptive movement. For behaviors in response to a simple stimulus, sensory neurons sometimes communicate directly with motor neurons; however, when animals are exposed to more complex stimuli, integration of sensory ...
Choline Signal Changes after Choline
Choline Signal Changes after Choline

... on the demands the situation may pose for the child's self-control. A child who can not sit still or is otherwise disruptive will be noticeable in school, but the inattentive daydreamer may be overlooked. The impulsive child who acts before thinking may be considered just as a discipline problem, wh ...
Nerve Growth Factor and Alzheimer`s Disease
Nerve Growth Factor and Alzheimer`s Disease

... disease has become a serious social problem. A new treatment method Journal of the Academic Society for Quality of Life ...
The functional anatomy of basal ganglia disorders
The functional anatomy of basal ganglia disorders

... excitatory and possibly glutamatergic 6'7. The neurotransmitter of SNc neurons is dopamine (DA). The striatum is primarily composed of projection neurons 8'9. Studies in rats suggested that striatal projection neurons give rise to extensive collateral projections with axons from a single neuron goin ...
The Adenosine Story Goes Ionic: CaV2.1
The Adenosine Story Goes Ionic: CaV2.1

... of a functionally responsive Ca2+ channel with preserved expression levels, but compromised primarily in G-protein-mediated inhibition.22 The hypothesis to be tested by Deboer et al.7 was clear: if CaV2.1 channels mediate some of adenosinergic actions on sleep, then these animals should show attenua ...
Neural mechanisms underlying the evolvability of behaviour
Neural mechanisms underlying the evolvability of behaviour

Deep Belief Networks Learn Context Dependent Behavior Florian Raudies *
Deep Belief Networks Learn Context Dependent Behavior Florian Raudies *

... [8,9,10,11]. Models of prefrontal cortex have attempted to simulate how neural circuits could provide the rules for action selection during behavioral tasks based on the context of the decision in addition to specific sensory input cues [12,13,14]. However, many previous models of prefrontal cortex ...
Warm pleasant feelings in the brain
Warm pleasant feelings in the brain

... primary, that is unlearned, reinforcers, and investigation of the neural mechanisms that are related to these stimuli and the feelings they arouse may provide a direct approach to understanding the brain mechanisms of emotion and indeed of decision-making (Cabanac, 2002; Rolls, 1999, 2005, 2008b). T ...
- Northumbria Research Link
- Northumbria Research Link

... Specifically, hypoxia results in a depression of synaptic transmission, presumably in those neurons that are not hypoxia resistant, which leads to neurons’ electrophysiological isolation from those neurons that are hypoxia resistant (i.e., no change in activity). Conversely, a brain rich in O2 suppl ...
Physiological Plasticity of Single Neurons in Auditory Cortex of the
Physiological Plasticity of Single Neurons in Auditory Cortex of the

... at the beginning of a session to produce a brief (2-5 s) pupillary dilation. The US was delivered to the subcutaneous tissue of the forepaw contralateral to the recording site via a pair of fine wire electrodes. Pupillary size was monitored by an infrared pupillometer (Cassady, Farley, Weinberger, & ...
Unique features of the human brainstem and cerebellum
Unique features of the human brainstem and cerebellum

... and Baker, 2006a). We referred to this region as the “calretinin (CR) area.” We subsequently found a CR area in the MVe of other species, including squirrel and macaque monkeys, chimpanzees, and humans (Baizer and Baker, 2006a; Baizer and Broussard, 2010; Baizer et al., 2013a). Figure 2 illustrates ...
Synaptic plasticity: taming the beast
Synaptic plasticity: taming the beast

... total level of synaptic efficacy. A frequent approach in neural network models is to globally adjust all the synapses onto each postsynaptic neuron based on its level of activity3. The adjustment can take two forms, depending on whether the synapses to a particular neuron are changed by the same amo ...
Single-Neuron Responses in Humans during Execution and
Single-Neuron Responses in Humans during Execution and

Mechanisms for generating and compensating for the
Mechanisms for generating and compensating for the

... gaze position, microsaccades can be understood by relating them to the larger voluntary saccades, which abruptly shift gaze position. Starting from this approach to microsaccade analysis, I show how it can lead to significant insight about the generation and functional role of these eye movements. L ...
Randy Kobes Poster Contest Workshop
Randy Kobes Poster Contest Workshop

... given off by protons in the brain and determines what type of tissue they belong to and where they are in space. In standard clinical practice, doctors use MRI to detect large causes of cognitive decline such as stroke and tumours. These scans cannot detect more subtle changes in the hippocampus. Th ...
Spike Train SIMilarity Space (SSIMS): A Framework for Single
Spike Train SIMilarity Space (SSIMS): A Framework for Single

... the behaviors performed in both a planar center-out reaching task and a 3D reaching and grasping task. The method provides a useful framework for data analysis and visualization well suited to the study of large neuronal ensembles engaged in complex behaviors. 2 Description of the SSIMS Algorithm Th ...
A phase I trial of deep brain stimulation of memory
A phase I trial of deep brain stimulation of memory

... and temporal areas, also have a propensity for fibrillar amyloid deposition as visualized at autopsy and in vivo using radioligands such as Pittsburgh compound B,9 both in AD patients and in nondemented older subjects.10,11 Recent evidence suggests amyloid pathology interferes with synaptic transmis ...
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Metastability in the brain

In the field of computational neuroscience, the theory of metastability refers to the human brain’s ability to integrate several functional parts and to produce neural oscillations in a cooperative and coordinated manner, providing the basis for conscious activity.Metastability, a state in which signals (such as oscillatory waves) fall outside their natural equilibrium state but persist for an extended period of time, is a principle that describes the brain’s ability to make sense out of seemingly random environmental cues. In the past 25 years, interest in metastability and the underlying framework of nonlinear dynamics has been fueled by advancements in the methods by which computers model brain activity.
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