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Neuroglia - wsscience
Neuroglia - wsscience

... 1. Input Zone: the ligand-gated ion channels are activated by neurotransmitters, or ligands, and secreted by presynaptic terminals. This activation creates a postsynaptic potential. 2. Integrative Zone: summates the postsynaptic potentials and initiates an action potential. Action potential depends ...
5. Membrane Transporters
5. Membrane Transporters

... membrane potential. Here are some important examples of secondary active transporters driven by the inward sodium leak: Calcium transport. There is a huge electrochemical gradient for calcium ions across cell membranes. In fact, no other ion is further from equilibrium than calcium. The extracellul ...
Physiological Acoustics
Physiological Acoustics

Active Transport, Diffusion and Osmosis
Active Transport, Diffusion and Osmosis

... Carrier Proteins • Bind to specific molecules, transport them across the membrane and release them • Carrier molecules change shape while transporting molecules • Usually transport ions or small polar molecules but can also transport amino acids and glucose • Have a lower rate of diffusion than cha ...
What is “membrane potential”
What is “membrane potential”

... Outside low [ K+] High [ Na+] ...
the nervous system
the nervous system

... 1. Neuron membrane maintains resting potential (+ outside - inside ) 2. Threshold stimulus is received 3. Sodium channels open 4. Sodium ions diffuse inward, depolarizing the membrane 5. Potassium channels open 6. Potassium ions diffuse outward, repolarizing the membrane 7. The resulting action pote ...
O`Kane
O`Kane

... B. a ligand-gated channel will typically open. C. an action potential will always occur. D. All of the above are correct. E. A and B are correct only. 24. Which of the following is correct regarding hyperpolarization? A. The transmembrane potential is less negative than the resting membrane potentia ...
4 How substances get in and out of cells
4 How substances get in and out of cells

Lecture 18 slides - Rob Phillips` lab
Lecture 18 slides - Rob Phillips` lab

File
File

... through a membrane by fluid or hydrostatic pressure ...
Lecture 12 - Taft College
Lecture 12 - Taft College

... By convention the voltage inside the cell (intracellular fluid ICF) is compared to the voltage out the cell (extracellular fluid ECF) therefore, negative ( − ) voltage. ...
Schwann cells - MsPhilip1234
Schwann cells - MsPhilip1234

... • What is the charge inside the neuron at rest? • Why is the cell negative inside and positive outside? (be specific) ...
The Importance of Water
The Importance of Water

... • Water moves through cells but independently enters and exits each cell ...
Nervous System: Nervous Tissue (Chapter 12) Lecture Materials for
Nervous System: Nervous Tissue (Chapter 12) Lecture Materials for

... -two categories of cells:! 1. Neurons: conduct nervous impulses! 2. Neuroglia / glial cells: “nerve glue”, ! ...
HOMEOSTASIS AND CELL TRANSPORT
HOMEOSTASIS AND CELL TRANSPORT

Active Transport
Active Transport

Huisman and Bisseling.
Huisman and Bisseling.

Nervous System
Nervous System

steps in nerve impulse transmission
steps in nerve impulse transmission

... 3. UNDERSHOOT (AKA REFRACTORY PERIOD)  Na and K channels close but NaK pump restores order (-70mV) after hyperpolarization ...
Bad Fish
Bad Fish

... If a cell starts at resting potential (-70mv), and then is stimulated: A. The membrane voltage will become < -70mV, because Na+ will move OUT of the cell B. The membrane voltage will become >-70mV, because Na+ will move OUT of the cell. C. The membrane voltage will become < -70mV because Na+ will m ...
THE CELL
THE CELL

HLFinalcell
HLFinalcell

No Slide Title
No Slide Title

... Example: ___ ~ opens Na+ channels An __________ in postsynaptic membrane potential (_________ ~ ...
An Interactive Lecture Guide to help you understand THE
An Interactive Lecture Guide to help you understand THE

... concentration gradient means to move from HIGH to LOW concentration. To move “up” or “against” a concentration gradient means to move from LOW to HIGH concentration. ...
Slide 1
Slide 1

... FIGURE 5.2 Differential distribution of ions inside and outside plasma membrane of neurons and neuronal processes, showing ionic channels for Na+, K+, Cl−, and Ca2+, as well as an electrogenic Na+–K+ ionic pump (also known as Na+, K+-ATPase). Concentrations (in millimoles except that for intracellu ...
< 1 ... 140 141 142 143 144 145 146 147 148 ... 180 >

Membrane potential



Membrane potential (also transmembrane potential or membrane voltage) is the difference in electric potential between the interior and the exterior of a biological cell. With respect to the exterior of the cell, typical values of membrane potential range from –40 mV to –80 mV.All animal cells are surrounded by a membrane composed of a lipid bilayer with proteins embedded in it. The membrane serves as both an insulator and a diffusion barrier to the movement of ions. Ion transporter/pump proteins actively push ions across the membrane and establish concentration gradients across the membrane, and ion channels allow ions to move across the membrane down those concentration gradients. Ion pumps and ion channels are electrically equivalent to a set of batteries and resistors inserted in the membrane, and therefore create a voltage difference between the two sides of the membrane.Virtually all eukaryotic cells (including cells from animals, plants, and fungi) maintain a non-zero transmembrane potential, usually with a negative voltage in the cell interior as compared to the cell exterior ranging from –40 mV to –80 mV. The membrane potential has two basic functions. First, it allows a cell to function as a battery, providing power to operate a variety of ""molecular devices"" embedded in the membrane. Second, in electrically excitable cells such as neurons and muscle cells, it is used for transmitting signals between different parts of a cell. Signals are generated by opening or closing of ion channels at one point in the membrane, producing a local change in the membrane potential. This change in the electric field can be quickly affected by either adjacent or more distant ion channels in the membrane. Those ion channels can then open or close as a result of the potential change, reproducing the signal.In non-excitable cells, and in excitable cells in their baseline states, the membrane potential is held at a relatively stable value, called the resting potential. For neurons, typical values of the resting potential range from –70 to –80 millivolts; that is, the interior of a cell has a negative baseline voltage of a bit less than one-tenth of a volt. The opening and closing of ion channels can induce a departure from the resting potential. This is called a depolarization if the interior voltage becomes less negative (say from –70 mV to –60 mV), or a hyperpolarization if the interior voltage becomes more negative (say from –70 mV to –80 mV). In excitable cells, a sufficiently large depolarization can evoke an action potential, in which the membrane potential changes rapidly and significantly for a short time (on the order of 1 to 100 milliseconds), often reversing its polarity. Action potentials are generated by the activation of certain voltage-gated ion channels.In neurons, the factors that influence the membrane potential are diverse. They include numerous types of ion channels, some of which are chemically gated and some of which are voltage-gated. Because voltage-gated ion channels are controlled by the membrane potential, while the membrane potential itself is influenced by these same ion channels, feedback loops that allow for complex temporal dynamics arise, including oscillations and regenerative events such as action potentials.
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