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PATHWAYS FOR EMOTION : INTERACTIONS OF PREFRONTAL AND THE RHESUS MONKEY
... Olmos, 1990). Disruption of these pathways seriously a¡ects emotional expression, as exempli¢ed by the inability of patients with orbitofrontal lesions to respond autonomically in emotional situations (Damasio et al., 1990; for review see Kling and Steklis, 1976). Even though such patients have inta ...
... Olmos, 1990). Disruption of these pathways seriously a¡ects emotional expression, as exempli¢ed by the inability of patients with orbitofrontal lesions to respond autonomically in emotional situations (Damasio et al., 1990; for review see Kling and Steklis, 1976). Even though such patients have inta ...
Odorant Specificity of Single Olfactory Bulb Neurons to Amino Acids
... The axons of ORNs expressing like ORs converge onto specific target glomeruli in vertebrates in the olfactory bulb (OB) (Mombaerts et al. 1996; Ressler et al. 1994; Strotmann et al. 2000; Vassar et al. 1994) where they synapse onto apical dendrites of mitral/tufted relay neurons, forming a functiona ...
... The axons of ORNs expressing like ORs converge onto specific target glomeruli in vertebrates in the olfactory bulb (OB) (Mombaerts et al. 1996; Ressler et al. 1994; Strotmann et al. 2000; Vassar et al. 1994) where they synapse onto apical dendrites of mitral/tufted relay neurons, forming a functiona ...
Contacts among non-sister dendritic branches at
... would be if it shows that such process is under regulation. We examined whether the frequency of BDIs varied following manipulations of synaptic activity (Fig. 2E). The frequency (number per 100 μm dendrite) of bifurcations and DDIs was unchanged under all conditions. The frequency of BDIs was reduc ...
... would be if it shows that such process is under regulation. We examined whether the frequency of BDIs varied following manipulations of synaptic activity (Fig. 2E). The frequency (number per 100 μm dendrite) of bifurcations and DDIs was unchanged under all conditions. The frequency of BDIs was reduc ...
USMLE – What`s it for
... Learn the various pancreatic proteases and how they are regulated. Understand transamination and oxidative deamination, but don't memorize pathways. Spend more time on urea cycle and ammonia metabolism focusing on figures ...
... Learn the various pancreatic proteases and how they are regulated. Understand transamination and oxidative deamination, but don't memorize pathways. Spend more time on urea cycle and ammonia metabolism focusing on figures ...
Article
... compared to the time scale of an action potential or synaptic transmission [6–8]. Moreover, the duration of each cycle can change according to the circumstances [9]. In general, CPG networks consist of interconnected interneurons that generate motor patterns underlying rhythmic behaviors. Since inte ...
... compared to the time scale of an action potential or synaptic transmission [6–8]. Moreover, the duration of each cycle can change according to the circumstances [9]. In general, CPG networks consist of interconnected interneurons that generate motor patterns underlying rhythmic behaviors. Since inte ...
Effects of insulin under normal and low glucose on retinal
... Conclusions. Insulin was not required for normal retinal function as observed during 10 hours of perfusion. The differential responsiveness to insulin under low glucose of the b-wave versus the optic nerve response is thought to reflect suppression of glucose use by Muller (glial) cells rather than ...
... Conclusions. Insulin was not required for normal retinal function as observed during 10 hours of perfusion. The differential responsiveness to insulin under low glucose of the b-wave versus the optic nerve response is thought to reflect suppression of glucose use by Muller (glial) cells rather than ...
A history of mitochondrial diseases
... common MELAS mutation, m.3243A > G. There is also a good correlation between mutation load and severity of clinical features, best shown by the neuropathy, ataxia, and retinitis pigmentosa/maternally inherited Leigh (Fig. 6) (NARP/MILS) mutation, m.8993 T > G: when the mutation load is around 70–80% ...
... common MELAS mutation, m.3243A > G. There is also a good correlation between mutation load and severity of clinical features, best shown by the neuropathy, ataxia, and retinitis pigmentosa/maternally inherited Leigh (Fig. 6) (NARP/MILS) mutation, m.8993 T > G: when the mutation load is around 70–80% ...
Jennifer McFarland - University of Evansville Faculty Web sites
... since neural cell division is not standard in adulthood. Therefore, many of the growth factors that ...
... since neural cell division is not standard in adulthood. Therefore, many of the growth factors that ...
Autism: A Review of Biological Bases, Assessment, and
... the presynaptic end of a tether between two cells during synapse development (Graf, Zhang, Jin, Linhoff, & Craig, 2005). SHANK3 is a scaffolding protein that assists in dendrite growth and positioning within excitatory synapses (Roussignol et al., 2005). Disruptions in the formation or transportatio ...
... the presynaptic end of a tether between two cells during synapse development (Graf, Zhang, Jin, Linhoff, & Craig, 2005). SHANK3 is a scaffolding protein that assists in dendrite growth and positioning within excitatory synapses (Roussignol et al., 2005). Disruptions in the formation or transportatio ...
IL-10 Alters Immunoproteostasis in APP Mice, Increasing Plaque
... ‘‘immunoproteostasis.’’ In a contextually dependent fashion, immunoproteostasis can have positive or negative effects on the proteinopathy and degenerative phenotype. Because of these effects and the plethora of therapeutic targets in the innate immune system, there is considerable interest in manip ...
... ‘‘immunoproteostasis.’’ In a contextually dependent fashion, immunoproteostasis can have positive or negative effects on the proteinopathy and degenerative phenotype. Because of these effects and the plethora of therapeutic targets in the innate immune system, there is considerable interest in manip ...
Regulation of neurons in the dorsal motor nucleus of the vagus by
... application of 100 µM resveratrol the frequency of sEPSCs significantly increased to 4.2 ± 0.8 Hz (range from 0.8 to 8.2 Hz, n = 8, p < 0.05) (Figures 1A–C). The average amplitude of sEPSCs was 13.2 ± 1.4 pA (range from 7.5 to 19.2 pA) before and 10.3 ± 0.6 pA (range from 8.0 to 13.7 pA) after appli ...
... application of 100 µM resveratrol the frequency of sEPSCs significantly increased to 4.2 ± 0.8 Hz (range from 0.8 to 8.2 Hz, n = 8, p < 0.05) (Figures 1A–C). The average amplitude of sEPSCs was 13.2 ± 1.4 pA (range from 7.5 to 19.2 pA) before and 10.3 ± 0.6 pA (range from 8.0 to 13.7 pA) after appli ...
Anticipated synchronization in neuronal circuits
... systems coupled in a master-slave configuration when the slave is subject to a negative delayed self-feedback. Many examples of AS dynamics have been found in different systems, however, theoretical and experimental evidence for it in the brain has been lacking. In this thesis work we investigate th ...
... systems coupled in a master-slave configuration when the slave is subject to a negative delayed self-feedback. Many examples of AS dynamics have been found in different systems, however, theoretical and experimental evidence for it in the brain has been lacking. In this thesis work we investigate th ...
Comparison of Primate Prefrontal and Inferior Temporal
... fundamental for normal cognition because it gives meaning to our sensory environment. Several recent studies have reported neuronal correlates of visual categories in two interconnected cortical areas involved in visual recognition, memory, and other visual functions: the inferior temporal cortex (I ...
... fundamental for normal cognition because it gives meaning to our sensory environment. Several recent studies have reported neuronal correlates of visual categories in two interconnected cortical areas involved in visual recognition, memory, and other visual functions: the inferior temporal cortex (I ...
A forward genetic screen with a thalamocortical emx2
... guidance and cortical morphogenesis phenotypes, it was crossed to the well-known cortical lamination mutant reeler (Figure 2). In reeler mutant brains, cortical layers are roughly inverted, and the subplate cells remain superficial [36]. The TCA-TLZ reporter shows that in control brains at P0 (Figur ...
... guidance and cortical morphogenesis phenotypes, it was crossed to the well-known cortical lamination mutant reeler (Figure 2). In reeler mutant brains, cortical layers are roughly inverted, and the subplate cells remain superficial [36]. The TCA-TLZ reporter shows that in control brains at P0 (Figur ...
Specialized prefrontal "auditory fields": organization of primate
... mediates the most complex and abstract cognitive tasks (Figure 1; reviewed in Barbas et al., 2002; Burgess et al., 2007; Koechlin and Hyafil, 2007; Smith et al., 2007; Badre and D’Esposito, 2009). The frontopolar cortex is situated in the most anterior part of the prefrontal cortex, extending from t ...
... mediates the most complex and abstract cognitive tasks (Figure 1; reviewed in Barbas et al., 2002; Burgess et al., 2007; Koechlin and Hyafil, 2007; Smith et al., 2007; Badre and D’Esposito, 2009). The frontopolar cortex is situated in the most anterior part of the prefrontal cortex, extending from t ...
Similar Inhibitory Processes Dominate the Responses of Cat Lateral
... recurrent inhibition, as this nucleus receives a massive input from the LAT nucleus but does not reciprocate this projection (Krettek and Price 1978). In addition, the LAT nucleus itself was stimulated to assess the influence of intrinsic connections. Histological controls confirmed the electrode pl ...
... recurrent inhibition, as this nucleus receives a massive input from the LAT nucleus but does not reciprocate this projection (Krettek and Price 1978). In addition, the LAT nucleus itself was stimulated to assess the influence of intrinsic connections. Histological controls confirmed the electrode pl ...
MAP2 and Tau Segregate into Dendritic and Axonal Domains After
... has elaborated 2 short, thick neurites and a long, thin neurite that does not branch until its terminal extension. Despite the axonal features of the long neurite, it is MAP2-immunoreactive at this early time point. Bar, 20 pm. C, A neuron that has attained a more complex appearance, including terti ...
... has elaborated 2 short, thick neurites and a long, thin neurite that does not branch until its terminal extension. Despite the axonal features of the long neurite, it is MAP2-immunoreactive at this early time point. Bar, 20 pm. C, A neuron that has attained a more complex appearance, including terti ...
Probing Allosteric Binding Sites of the Maize
... adjacent sites within a subunit (Morell et al., 1988; Boehlein et al., 2008). Like Pi, sulfate reverses 3-PGAmediated activation for the potato, A. tumefaciens, and maize enzymes (I0.5 = 2.8 mM in the presence of 6 mM 3-PGA, potato tuber AGPase; I0.5 = 20 mM in the presence of 2.5 mM 3-PGA, maize en ...
... adjacent sites within a subunit (Morell et al., 1988; Boehlein et al., 2008). Like Pi, sulfate reverses 3-PGAmediated activation for the potato, A. tumefaciens, and maize enzymes (I0.5 = 2.8 mM in the presence of 6 mM 3-PGA, potato tuber AGPase; I0.5 = 20 mM in the presence of 2.5 mM 3-PGA, maize en ...
Lecture 14 Olfaction
... cannot smell it and might put on a lot. • Receptor adaptation: The biochemical phenomenon that occurs after continuous exposure to an odorant, whereby the receptors stop responding to the odorant and ...
... cannot smell it and might put on a lot. • Receptor adaptation: The biochemical phenomenon that occurs after continuous exposure to an odorant, whereby the receptors stop responding to the odorant and ...
Brain-derived neurotrophic factor in the development of epilepsy
... ISBN 951-781-978-1 ISBN 951-27-0083-2 (PDF) ISSN 1458-7335 ...
... ISBN 951-781-978-1 ISBN 951-27-0083-2 (PDF) ISSN 1458-7335 ...
Different neurotrophins are expressed and act in a developmental
... raised the issue of whether similar correlations between target field innervation, neurotrophin synthesis and neuronal responsiveness exist for these more recently identified neurotrophins. This is especially pertinent as these neurotrophins, in contrast to NGF, have additional roles in neuronal dev ...
... raised the issue of whether similar correlations between target field innervation, neurotrophin synthesis and neuronal responsiveness exist for these more recently identified neurotrophins. This is especially pertinent as these neurotrophins, in contrast to NGF, have additional roles in neuronal dev ...
2015 Cosyne Program
... to foster invention both within Qualcomm and in the community. Our researchers and computational scientists engage in a wide variety of exciting and technically challenging projects—including exploring applications of systems neuroscience research to machine learning, to enable "smarter" and more eff ...
... to foster invention both within Qualcomm and in the community. Our researchers and computational scientists engage in a wide variety of exciting and technically challenging projects—including exploring applications of systems neuroscience research to machine learning, to enable "smarter" and more eff ...
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... circuits. On the other hand, for systems neurophysiologists working with alert animals, who have long recorded single neurons with tremendous success in uncovering neural correlates of behavior, understanding coordinated neural population patterns in a circuit represents a new challenge. Moreover, c ...
... circuits. On the other hand, for systems neurophysiologists working with alert animals, who have long recorded single neurons with tremendous success in uncovering neural correlates of behavior, understanding coordinated neural population patterns in a circuit represents a new challenge. Moreover, c ...
Clinical neurochemistry
![](https://commons.wikimedia.org/wiki/Special:FilePath/Neuron_with_mHtt_inclusion.jpg?width=300)
Clinical neurochemistry is the field of neurological biochemistry which relates biochemical phenomena to clinical symptomatic manifestations in humans. While neurochemistry is mostly associated with the effects of neurotransmitters and similarly-functioning chemicals on neurons themselves, clinical neurochemistry relates these phenomena to system-wide symptoms. Clinical neurochemistry is related to neurogenesis, neuromodulation, neuroplasticity, neuroendocrinology, and neuroimmunology in the context of associating neurological findings at both lower and higher level organismal functions.