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Information Processing at the Calyx of Held Under Natural Conditions
... that the nucleus generates one output spike for every incoming spike, thereby working as a sign-inverting relay. In terms of information processing this corresponds to a multiplication with -1, one of the easiest manipulations possible. How would more complex transformations look like? A cell with o ...
... that the nucleus generates one output spike for every incoming spike, thereby working as a sign-inverting relay. In terms of information processing this corresponds to a multiplication with -1, one of the easiest manipulations possible. How would more complex transformations look like? A cell with o ...
an integrative theory of prefrontal cortex function
... maintenance of patterns of activity that represent goals and the means to achieve them. They provide bias signals throughout much of the rest of the brain, affecting not only visual processes but also other sensory modalities, as well as systems responsible for response execution, memory retrieval, ...
... maintenance of patterns of activity that represent goals and the means to achieve them. They provide bias signals throughout much of the rest of the brain, affecting not only visual processes but also other sensory modalities, as well as systems responsible for response execution, memory retrieval, ...
Effects of Molecular Crowding on Binding Affinity of Dihydrofolate to
... DHFR is not only found in mammals, but also in bacteria. One isoform is the R67 DHFR, which is carried by an R-plasmid or resistance plasmid. In comparison to the chromosomal DHFR, R67 has different characteristics. For instance, R67 DHFR has a lower affinity for DHF than the chromosomal form 1. Ad ...
... DHFR is not only found in mammals, but also in bacteria. One isoform is the R67 DHFR, which is carried by an R-plasmid or resistance plasmid. In comparison to the chromosomal DHFR, R67 has different characteristics. For instance, R67 DHFR has a lower affinity for DHF than the chromosomal form 1. Ad ...
Is the Lateral Septum's Inhibitory Influence on the Amygdala Mediated... GABA-ergic Neurons? Mason Austin
... used to examine the neural response of brain areas proposed to be involved in the production and modulation of anxiety. Electrophysiological activity of a group of cells in a particular region may be recorded after administration of anxiogenic or anxiolytic chemicals, stimulation of other brain area ...
... used to examine the neural response of brain areas proposed to be involved in the production and modulation of anxiety. Electrophysiological activity of a group of cells in a particular region may be recorded after administration of anxiogenic or anxiolytic chemicals, stimulation of other brain area ...
Afferent Fiber Remodeling in the Somatosensory Thalamus of Mice
... (Arsenault and Zhang, 2006); innervation of a single lemniscal fiber to a mature V2 VPM neuron is completed via developmental synapse elimination (Arsenault and Zhang, 2006; Takeuchi et al., 2014). We have previously demonstrated that complete transection of the primary whisker sensory nerve of mice ...
... (Arsenault and Zhang, 2006); innervation of a single lemniscal fiber to a mature V2 VPM neuron is completed via developmental synapse elimination (Arsenault and Zhang, 2006; Takeuchi et al., 2014). We have previously demonstrated that complete transection of the primary whisker sensory nerve of mice ...
Anatomy and Physiology of Smell
... Olfactory receptor genes account for ~1% of all expressed genes of the human genome Largest known vertebrate gene family Receptors not randomly distributed but confined to one of several nonoverlapping striplike zones Each cell is responsive to a wide, but circumscribed, range of stimuli Olfactory ...
... Olfactory receptor genes account for ~1% of all expressed genes of the human genome Largest known vertebrate gene family Receptors not randomly distributed but confined to one of several nonoverlapping striplike zones Each cell is responsive to a wide, but circumscribed, range of stimuli Olfactory ...
Information processing in the cortex: The relevance of coherent oscillations for neuronal communication
... • My parents, for all their loving support and patience, without which this thesis would never have been possible. ...
... • My parents, for all their loving support and patience, without which this thesis would never have been possible. ...
Principles of Neural Science - Weizmann Institute of Science
... Reflexes are involuntary coordinated patterns of muscle contraction and relaxation elicited by peripheral stimuli. They are typically isolated in animals in which motor pathways from higher brain centers to the spinal cord have been cut (such animals are called decerebrate or spinal animals dependin ...
... Reflexes are involuntary coordinated patterns of muscle contraction and relaxation elicited by peripheral stimuli. They are typically isolated in animals in which motor pathways from higher brain centers to the spinal cord have been cut (such animals are called decerebrate or spinal animals dependin ...
Document
... Injured tissues then release a variety of chemicals, including substance P, histamine, prostaglandins, serotonin, and bradykinin These are neurotransmitters that propagate pain message, or action potential, along sensory afferent nerve fibers to spinal cord These fibers terminate in dorsal horn of s ...
... Injured tissues then release a variety of chemicals, including substance P, histamine, prostaglandins, serotonin, and bradykinin These are neurotransmitters that propagate pain message, or action potential, along sensory afferent nerve fibers to spinal cord These fibers terminate in dorsal horn of s ...
Cell-intrinsic drivers of dendrite morphogenesis
... neurons of the Drosophila antennal lobe are crucial for olfactory processing. They receive excitatory input from olfactory receptor neurons in glomeruli and transmit signals to the mushroom body and lateral horn. Cerebellar granule neurons. The most numerous neurons of the brain, these offer an idea ...
... neurons of the Drosophila antennal lobe are crucial for olfactory processing. They receive excitatory input from olfactory receptor neurons in glomeruli and transmit signals to the mushroom body and lateral horn. Cerebellar granule neurons. The most numerous neurons of the brain, these offer an idea ...
Isolation of drug target protein
... Isolation of drug target protein Summary Chemical Biology is known as new biological approach for analysis of the interaction between small molecules (chemicals) and target molecules in the cells. FG beads are the best tool for this purpose. We here introduce how to immobilize chemical on the FG bea ...
... Isolation of drug target protein Summary Chemical Biology is known as new biological approach for analysis of the interaction between small molecules (chemicals) and target molecules in the cells. FG beads are the best tool for this purpose. We here introduce how to immobilize chemical on the FG bea ...
GLUCOCORTICOIDS INCREASE CNS INFLAMMATION
... does GR (5.0 nM), and this difference is a large part of the reason for concentration-dependent differences in GC activity (15). At basal GC levels, GCs predominantly bind to MR and only slightly occupy GR. In the early stage of a stressor, MR becomes saturated and the occupancy of GR is increased. ...
... does GR (5.0 nM), and this difference is a large part of the reason for concentration-dependent differences in GC activity (15). At basal GC levels, GCs predominantly bind to MR and only slightly occupy GR. In the early stage of a stressor, MR becomes saturated and the occupancy of GR is increased. ...
PPT
... – LFP can be used to successfully decode a movement direction – About 50ms after this is possible based on SUA/MUA – LFP+SUA/MUA results in higher decoding accuracy ...
... – LFP can be used to successfully decode a movement direction – About 50ms after this is possible based on SUA/MUA – LFP+SUA/MUA results in higher decoding accuracy ...
NROSCI/BIOSC 1070 and MSNBIO 2070 September 12, 2016
... Hormonal release mechanisms from the anterior and posterior pituitary are completely different. Hormones released from the anterior pituitary are produced by endocrine cells located in this glandular tissue. However, the synthesis and release of these hormones is tightly controlled by the hypothalam ...
... Hormonal release mechanisms from the anterior and posterior pituitary are completely different. Hormones released from the anterior pituitary are produced by endocrine cells located in this glandular tissue. However, the synthesis and release of these hormones is tightly controlled by the hypothalam ...
Article Full Text PDF
... Korn et al., 1990). They receive afferent sensory inputs from a variety of sources, notably auditory, and also many inhibitory inputs. These inhibitory signals determine the threshold and the input-output relations of the cell, and are a major factor in regulation of its function (Faber and Korn, 19 ...
... Korn et al., 1990). They receive afferent sensory inputs from a variety of sources, notably auditory, and also many inhibitory inputs. These inhibitory signals determine the threshold and the input-output relations of the cell, and are a major factor in regulation of its function (Faber and Korn, 19 ...
Pleiotrophin is a Neurotrophic Factor for Spinal Motor Neurons
... a mitogen for NIH 3T3 cells (11), is a member of the midkine family that has cysteine- and basic amino acid-rich residues distinct from other heparin binding growth factor families (12–14). In addition to the mitogenic effect on fibroblasts, PTN has activity in a variety of tissues and cell types (1 ...
... a mitogen for NIH 3T3 cells (11), is a member of the midkine family that has cysteine- and basic amino acid-rich residues distinct from other heparin binding growth factor families (12–14). In addition to the mitogenic effect on fibroblasts, PTN has activity in a variety of tissues and cell types (1 ...
An Integrative Theory on Prefrontal Cortex Function
... maintenance of patterns of activity that represent goals and the means to achieve them. They provide bias signals throughout much of the rest of the brain, affecting not only visual processes but also other sensory modalities, as well as systems responsible for response execution, memory retrieval, ...
... maintenance of patterns of activity that represent goals and the means to achieve them. They provide bias signals throughout much of the rest of the brain, affecting not only visual processes but also other sensory modalities, as well as systems responsible for response execution, memory retrieval, ...
Glucose Regulation by Dr Sarma
... 1. All the fuels are inter changeable in the body 2. It is the total calorie restriction that is important in Obesity and T2D ...
... 1. All the fuels are inter changeable in the body 2. It is the total calorie restriction that is important in Obesity and T2D ...
Vanadium-Binding Proteins (Vanabins)
... dissociation constant was 2.1 × 10-5 M. By contrast, vanabin2 bound to 20 vanadium(IV) ions per protein for a dissociation constant of 2.3 × 10-5 M. The dissociation constants of these vanabins are quite similar, although vanabin2 has twice as many apparent binding sites as vanabin1. The difference ...
... dissociation constant was 2.1 × 10-5 M. By contrast, vanabin2 bound to 20 vanadium(IV) ions per protein for a dissociation constant of 2.3 × 10-5 M. The dissociation constants of these vanabins are quite similar, although vanabin2 has twice as many apparent binding sites as vanabin1. The difference ...
biolsci.org - International Journal of Biological Sciences
... ThiE catalyzes the THZ-P and HMP-PP to yield ThMP. The solved ThiE crystal structures of B. subtilis and M. tuberculosis (http://hdl.handle.net/1813/ 13623) have similar structure [58]. It is dimer and has an α/β structure with a TIM barrel fold and a core of eight β-strands flanked by eight α-helic ...
... ThiE catalyzes the THZ-P and HMP-PP to yield ThMP. The solved ThiE crystal structures of B. subtilis and M. tuberculosis (http://hdl.handle.net/1813/ 13623) have similar structure [58]. It is dimer and has an α/β structure with a TIM barrel fold and a core of eight β-strands flanked by eight α-helic ...
Discrete coding of stimulus value, reward expectation, and reward
... Electrolytic lesions were made by passing electrical current through the tip of the electrode and into ...
... Electrolytic lesions were made by passing electrical current through the tip of the electrode and into ...
Excitatory Postsynaptic Potentials Trigger a Plateau Potential in Rat
... neurons at hyperpolarized states. J Neurophysiol 86: 1816 –1825, 2001. The subthalamic nucleus (STN) directly innervates the output structures of the basal ganglia, playing a key role in basal ganglia function. It is therefore important to understand the regulatory mechanisms for the activity of STN ...
... neurons at hyperpolarized states. J Neurophysiol 86: 1816 –1825, 2001. The subthalamic nucleus (STN) directly innervates the output structures of the basal ganglia, playing a key role in basal ganglia function. It is therefore important to understand the regulatory mechanisms for the activity of STN ...
View PDF - MRC Brain Network Dynamics Unit
... potentials were typically between 0.3 and 0.8 mV in amplitude and always exhibited an initial positive deflection. Recordings of spontaneous activity typically lasted for 20 – 40 min. Activity was recorded, first, during slow-wave activity (SWA), which accompanies deep anesthesia and is similar to a ...
... potentials were typically between 0.3 and 0.8 mV in amplitude and always exhibited an initial positive deflection. Recordings of spontaneous activity typically lasted for 20 – 40 min. Activity was recorded, first, during slow-wave activity (SWA), which accompanies deep anesthesia and is similar to a ...
Fig. 1
... normalized to the values obtained for a control antibody to correct for variation in the amount of total protein loaded. 2.5. Statistical analysis All experiments were repeated at least three times and the results are presented as the mean ± standard error of the mean. Statistical differences betwee ...
... normalized to the values obtained for a control antibody to correct for variation in the amount of total protein loaded. 2.5. Statistical analysis All experiments were repeated at least three times and the results are presented as the mean ± standard error of the mean. Statistical differences betwee ...
Clinical neurochemistry
![](https://commons.wikimedia.org/wiki/Special:FilePath/Neuron_with_mHtt_inclusion.jpg?width=300)
Clinical neurochemistry is the field of neurological biochemistry which relates biochemical phenomena to clinical symptomatic manifestations in humans. While neurochemistry is mostly associated with the effects of neurotransmitters and similarly-functioning chemicals on neurons themselves, clinical neurochemistry relates these phenomena to system-wide symptoms. Clinical neurochemistry is related to neurogenesis, neuromodulation, neuroplasticity, neuroendocrinology, and neuroimmunology in the context of associating neurological findings at both lower and higher level organismal functions.