Are there differences between the secretion characteristics of NGF
... et al. [(1996) Mol Cell Neurosci 7:222–238] reported that the high potassium-mediated secretion of brain-derived neurotrophic factor (BDNF) from hippocampal cultures was dependent on extracellular calcium. Mowla et al. [(1997) Proc 27th Annu Meet Soc Neurosci New Orleans 875.10] reported on even fur ...
... et al. [(1996) Mol Cell Neurosci 7:222–238] reported that the high potassium-mediated secretion of brain-derived neurotrophic factor (BDNF) from hippocampal cultures was dependent on extracellular calcium. Mowla et al. [(1997) Proc 27th Annu Meet Soc Neurosci New Orleans 875.10] reported on even fur ...
General, Organic, and Biological Chemistry
... Chemistry Link to Health Incomplete Combustion: Toxicity of Carbon Monoxide 247 ...
... Chemistry Link to Health Incomplete Combustion: Toxicity of Carbon Monoxide 247 ...
all-or-nothing principle
... document may not be copied, scanned, duplicated, forwarded, distributed, or posted on a website, in whole or part. ...
... document may not be copied, scanned, duplicated, forwarded, distributed, or posted on a website, in whole or part. ...
The Mammalian Diving Response: An Enigmatic Reflex to Preserve
... and ABP, respectively. Pharmacological studies using antagonists/agonists show that HR and ABP responses can be blocked selectively while preserving the other two reflexes (62, 168, 254), suggesting the independence of these reflexes after peripheral blockade but implying nothing about their central ...
... and ABP, respectively. Pharmacological studies using antagonists/agonists show that HR and ABP responses can be blocked selectively while preserving the other two reflexes (62, 168, 254), suggesting the independence of these reflexes after peripheral blockade but implying nothing about their central ...
Neuropathological Characteristics of Brachial Plexus Avulsion Injury
... biostatistician on the project, it was determined that the study was sufficiently powered as described in the “Results” section. Prior to surgery, animals were fasted with free access to water for 12 hours. Anesthesia was induced via intramuscular injection of midazolam (0.5–0.6 mg/kg) and ketamine ...
... biostatistician on the project, it was determined that the study was sufficiently powered as described in the “Results” section. Prior to surgery, animals were fasted with free access to water for 12 hours. Anesthesia was induced via intramuscular injection of midazolam (0.5–0.6 mg/kg) and ketamine ...
Section Summary
... • Osmometric thirst occurs when the solute concentration of the interstitial fluid increases. This increase draws water out of the cells, and they shrink in volume. • Osmometric Thirst • thirst produced by an increase in the osmotic pressure of the interstitial fluid relative to the intracellular fl ...
... • Osmometric thirst occurs when the solute concentration of the interstitial fluid increases. This increase draws water out of the cells, and they shrink in volume. • Osmometric Thirst • thirst produced by an increase in the osmotic pressure of the interstitial fluid relative to the intracellular fl ...
The Organization of Behavioral Repertoire in Motor Cortex
... motor cortex and the caudal sectors of premotor cortex appeared to be at a similar hierarchical level, coordinating different but equally complex movements. Movements could not be consistently evoked from rostral premotor cortex. These results suggest a new framework in which (a) the primary motor c ...
... motor cortex and the caudal sectors of premotor cortex appeared to be at a similar hierarchical level, coordinating different but equally complex movements. Movements could not be consistently evoked from rostral premotor cortex. These results suggest a new framework in which (a) the primary motor c ...
THALAMOAMYGDALOID CONNECTIONS STUDIED BY THE
... and parataenial nucleus, are mostly bilateral. INTRODUCTION ...
... and parataenial nucleus, are mostly bilateral. INTRODUCTION ...
NIH Public Access - IIS Windows Server
... categories of mitochondrial disorders outlined above, focusing on their salient clinical manifestations and highlighting novel clinical entities. An outline of diagnostic clues for the various forms of mitochondrial disease, as well as potential therapeutic strategies, is also discussed. ...
... categories of mitochondrial disorders outlined above, focusing on their salient clinical manifestations and highlighting novel clinical entities. An outline of diagnostic clues for the various forms of mitochondrial disease, as well as potential therapeutic strategies, is also discussed. ...
Axonal Membranes and Their Domains: Assembly and Function of
... The specific subtypes of Nav channels at the AIS include Nav1.1, Nav1.2 and Nav1.6. Early in AIS development, Nav1.2 is the predominant channel found at the AIS; however, as the neuron matures, Nav1.6 becomes the primary channel (Boiko et al., 2003; Osorio et al., 2005). The reason for this shift in ...
... The specific subtypes of Nav channels at the AIS include Nav1.1, Nav1.2 and Nav1.6. Early in AIS development, Nav1.2 is the predominant channel found at the AIS; however, as the neuron matures, Nav1.6 becomes the primary channel (Boiko et al., 2003; Osorio et al., 2005). The reason for this shift in ...
Axon Physiology - Physiological Reviews
... pyramidal neurons. A: changes in intracellular Na⫹ during action potentials are largest in the AIS. A L5 pyramidal neuron was filled with the Na⫹-sensitive dye SBFI and the variations in fluorescence measured at different distances from the axon hillock. The signal is larger in the AIS (25 m) and r ...
... pyramidal neurons. A: changes in intracellular Na⫹ during action potentials are largest in the AIS. A L5 pyramidal neuron was filled with the Na⫹-sensitive dye SBFI and the variations in fluorescence measured at different distances from the axon hillock. The signal is larger in the AIS (25 m) and r ...
Excitatory and Inhibitory Vestibular Pathways to the Extraocular
... intracellular records in goldfish oculomotoneurons did not report inhibition (Korn and Bennett 1971), structural and neurophysiological observations in the goldfish horizontal canal system indicated reciprocal inhibition and excitation (Baker et al. 1986, 1987a, 1994). Eye velocity and position sign ...
... intracellular records in goldfish oculomotoneurons did not report inhibition (Korn and Bennett 1971), structural and neurophysiological observations in the goldfish horizontal canal system indicated reciprocal inhibition and excitation (Baker et al. 1986, 1987a, 1994). Eye velocity and position sign ...
Full-Text PDF
... to embed this bacteria within the biofilm matrix. SRB has been reported to exist in biofilm matrices that are electroactive [32] or are determined to impart localized biocorrosion [2,33,34]. The biofilm matrix not only serves to adhere SRB onto surfaces but also hinders penetration of biocides. This ...
... to embed this bacteria within the biofilm matrix. SRB has been reported to exist in biofilm matrices that are electroactive [32] or are determined to impart localized biocorrosion [2,33,34]. The biofilm matrix not only serves to adhere SRB onto surfaces but also hinders penetration of biocides. This ...
Activity dynamics and behavioral correlates of CA3 and CA1
... et al., 1990; O’Reilly and McClelland, 1994; Rolls and Kesner, 2006). However, whether such differences arise from intrinsic properties of single cells or circuit effects is not well understood. Previous single cell studies failed to find reliable regional differences (O’Keefe and Speakman, 1987; Bos ...
... et al., 1990; O’Reilly and McClelland, 1994; Rolls and Kesner, 2006). However, whether such differences arise from intrinsic properties of single cells or circuit effects is not well understood. Previous single cell studies failed to find reliable regional differences (O’Keefe and Speakman, 1987; Bos ...
Neuroimaging and neuropsychological findings in
... brain areas implicated in OCD by modulating efferents from the basal ganglia [18] . For example, dopamine D2 receptors are found in dorsal striatal caudate areas [17] and serotonin receptors are densely located in ventromedial caudate and nucleus accumbens regions [18] . Dopaminergic stimulation of ...
... brain areas implicated in OCD by modulating efferents from the basal ganglia [18] . For example, dopamine D2 receptors are found in dorsal striatal caudate areas [17] and serotonin receptors are densely located in ventromedial caudate and nucleus accumbens regions [18] . Dopaminergic stimulation of ...
Tang et al - Pro Aid Autisme
... (Penzes et al., 2011), a process that provides selection and maturation of synapses and neural circuits. While ASDs exhibit striking genetic and clinical heterogeneity, multiple ASD syndromes are caused by mutations in genes that act to inhibit mammalian target of rapamycin (mTOR) kinase, including ...
... (Penzes et al., 2011), a process that provides selection and maturation of synapses and neural circuits. While ASDs exhibit striking genetic and clinical heterogeneity, multiple ASD syndromes are caused by mutations in genes that act to inhibit mammalian target of rapamycin (mTOR) kinase, including ...
Laminar Selectivity of the Cholinergic Suppression of Synaptic
... additional simulations, the L,, matrix started with random initial connectivity, allowing more complex transformations of entorhinal cortex output to be formed by self-organization of the synapses in s. l-m. In keeping with physiological evidence showing that synapses in s. l-m have a much weaker in ...
... additional simulations, the L,, matrix started with random initial connectivity, allowing more complex transformations of entorhinal cortex output to be formed by self-organization of the synapses in s. l-m. In keeping with physiological evidence showing that synapses in s. l-m have a much weaker in ...
12659942_three sites - University of Canterbury
... (Trp + Phe + Tyr) exceeds the effects that arise from the equivalent binary combinations of Trp + Phe or Trp + Tyr (WFF or WYY), indicating that Tyr specifically augments the inhibition of this enzyme by Trp and Phe. Crystal structures of DAH7PS reveal three distinct aromatic amino acid binding site ...
... (Trp + Phe + Tyr) exceeds the effects that arise from the equivalent binary combinations of Trp + Phe or Trp + Tyr (WFF or WYY), indicating that Tyr specifically augments the inhibition of this enzyme by Trp and Phe. Crystal structures of DAH7PS reveal three distinct aromatic amino acid binding site ...
The cAMP response element binding protein (CREB) and its role in
... 3.3. Activation by an elevation of the cytosolic Ca2+ level Like cAMP, Ca2+ functions as a second messenger in a variety of cellular processes (Ghosh and Greenberg, 1995). In the nervous system, changes in membrane potential can increase intracellular Ca2+ levels via several mechanisms. Release of n ...
... 3.3. Activation by an elevation of the cytosolic Ca2+ level Like cAMP, Ca2+ functions as a second messenger in a variety of cellular processes (Ghosh and Greenberg, 1995). In the nervous system, changes in membrane potential can increase intracellular Ca2+ levels via several mechanisms. Release of n ...
Wasp Voodoo Rituals, Venom-Cocktails, and the Zombification of Cockroach Hosts SYMPOSIUM Frederic Libersat
... involved, their means of delivery, their neuronal targets, and their methods of action within the host’s CNS, are today little understood. One exception to this and probably the best and only well-understood example of underlying neuronal mechanisms of a wasp-induced behavioral manipulation is the r ...
... involved, their means of delivery, their neuronal targets, and their methods of action within the host’s CNS, are today little understood. One exception to this and probably the best and only well-understood example of underlying neuronal mechanisms of a wasp-induced behavioral manipulation is the r ...
Chapter 02: Biopsychology, Neuroscience, and Human Nature
... Incorrect. Down syndrome is not an adaptive quality of human beings; rather, it is an illness that is caused by having one too many chromosomes. d. language Correct. The ability to use language as a means of communication is certainly adaptive to human beings. e. the ability to program a cell phone ...
... Incorrect. Down syndrome is not an adaptive quality of human beings; rather, it is an illness that is caused by having one too many chromosomes. d. language Correct. The ability to use language as a means of communication is certainly adaptive to human beings. e. the ability to program a cell phone ...
Engineering subunit association of multisubunit proteins
... analysis of complexes, assumes, as a first-order approximation, rigid body association. The same binding free energy evaluation model could also be used to address the third problem for further design of dimeric streptavidins, in which the biotinbinding affinity, reduced due to the subunit separatio ...
... analysis of complexes, assumes, as a first-order approximation, rigid body association. The same binding free energy evaluation model could also be used to address the third problem for further design of dimeric streptavidins, in which the biotinbinding affinity, reduced due to the subunit separatio ...
Dendritic Signal Integration
... determine cell-specific specializations of dendritic integration. Similarly, dendritic integration of fast excitatory and inhibitory synapses is influenced by the modulatory state of the network, which is determined by slower, neuromodulatory transmitters acting on Gprotein-coupled receptors, in tur ...
... determine cell-specific specializations of dendritic integration. Similarly, dendritic integration of fast excitatory and inhibitory synapses is influenced by the modulatory state of the network, which is determined by slower, neuromodulatory transmitters acting on Gprotein-coupled receptors, in tur ...
Time course of post-traumatic mitochondrial oxidative damage and
... Xiong, 1997; Sullivan et al, 1999a, b, c), and cell death (Robertson, 2004). Most convincing with regard to the importance of mitochondrial failure in secondary brain injury, pharmacological agents that target mitochondria have been shown to be neuroprotective. Administration of cyclosporine A (CsA) ...
... Xiong, 1997; Sullivan et al, 1999a, b, c), and cell death (Robertson, 2004). Most convincing with regard to the importance of mitochondrial failure in secondary brain injury, pharmacological agents that target mitochondria have been shown to be neuroprotective. Administration of cyclosporine A (CsA) ...
Clinical neurochemistry
Clinical neurochemistry is the field of neurological biochemistry which relates biochemical phenomena to clinical symptomatic manifestations in humans. While neurochemistry is mostly associated with the effects of neurotransmitters and similarly-functioning chemicals on neurons themselves, clinical neurochemistry relates these phenomena to system-wide symptoms. Clinical neurochemistry is related to neurogenesis, neuromodulation, neuroplasticity, neuroendocrinology, and neuroimmunology in the context of associating neurological findings at both lower and higher level organismal functions.