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WHAT SHOULD WE KNOW ABOUT MARIJUANA goes to ARTCLES
WHAT SHOULD WE KNOW ABOUT MARIJUANA goes to ARTCLES

... Marijuana users who have taken large doses of the drug may experience an acute psychosis, which includes hallucinations, delusions, and a loss of the sense of personal identity. Short-term psychotic reactions to high concentrations of THC are distinct from longer-lasting, schizophrenia-like disorder ...
Fast Readout of Object Identity from Macaque Inferior Temporal Cortex
Fast Readout of Object Identity from Macaque Inferior Temporal Cortex

... spikes over a short time interval (100- to 300ms interval divided into bins of 50 ms in this case) (11, 23, 24, 28). This is notable considering the high trial-to-trial variability of cortical neurons (27). The IT population performance is also robust to biological noise sources such as neuronal dea ...
1 - Projeto Andar de Novo
1 - Projeto Andar de Novo

... specific way and after 10-20 minutes of cell contact the protein is internalized and accumulates in endocytic organelles. Co-localization studies with markers of subcellular organelles indicated that fluorescent STI-1 is internalized to flotillin-1 positive vesicles and is then found in Rab7 positiv ...
1From neuronal activity to scalp potential fields - Assets
1From neuronal activity to scalp potential fields - Assets

... Spiking correlates with the less focal, and typically slower and weaker extracellular field potentials15 . These reflect neural mass activity due to linear superposition of those fields which do not form closed field current loops. In brain regions such as the neocortex, this extracellular activity ...
Distinctive Personality Traits and Neural Correlates Associated with
Distinctive Personality Traits and Neural Correlates Associated with

... Risk of Stimulant Dependence Karen D. Ersche, P. Simon Jones, Guy B. Williams, Dana G. Smith, Edward T. Bullmore, and Trevor W. Robbins Background: Stimulant drugs such as cocaine and amphetamine have a high abuse liability, but not everyone who uses them develops dependence. However, the risk for d ...
Patterns of neuronal migration in the embryonic cortex
Patterns of neuronal migration in the embryonic cortex

... in the MZ before turning again to enter the cortical plate to reach their final positions [36]. Interestingly, a proportion of tangentially migrating neurons from all cortical layers were observed to undergo ventricle-directed migration to the VZ in slice-culture preparations [37]. Upon reaching the ...
Deleterious effects of amyloid beta peptide in the neuromuscular
Deleterious effects of amyloid beta peptide in the neuromuscular

... Amyotrophic lateral sclerosis (ALS) is a devastating and fatal neurodegenerative disease of adults which preferentially attacks the neuromotor system. It has been shown that Amyloid-beta (Aβ) levels are elevated in spinal cords of late-stage superoxide dismutase 1 (SOD1) G93A mice (model of familial ...
Mechanisms underlying working memory for novel information
Mechanisms underlying working memory for novel information

... Functional neuroimaging studies support the idea that working memory for novel stimuli requires the additional recruitment of parahippocampal regions. Early functional neuroimaging studies of working memory emphasized the role of prefrontal and parietal cortices, and most studies were carried out us ...
Non-Cell-Autonomous Effect of Human SOD1G37R
Non-Cell-Autonomous Effect of Human SOD1G37R

... hESC-derived rosettes expressed motor neuron progenitor markers such as Pax6, Nestin, Olig2, and Islet1 after 2–3 weeks of differentiation (Figures 1A–1D). After 4 weeks under differentiation conditions, the cells started to express panneuronal markers such as TuJ1, and after 6–8 weeks, the cells ex ...
Cardiomyopathy in Children And Adolescents: What Begins in
Cardiomyopathy in Children And Adolescents: What Begins in

... Incidence of cardiomyopathy in children  Incidence 1.13-1.24/100,000  40% of children ultimately die of their disease (unaltered over decades)  Highest incidence is in the first year of life, (greater than 8 to 12 times that at any other time in life)  Second peak occurs in adolescence  Higher ...
Excellence in Clinical Neurosurgery: Practice and Judgment Make
Excellence in Clinical Neurosurgery: Practice and Judgment Make

... have proceeded directly to craniotomy for resection of an MEG spike, a so-called ‘‘clusterectomy’’ (Figure 6). Finally, in the setting of status epilepticus, a neurological emergency that has high morbidity and mortality rates, an MEG may demonstrate localization of MEG spike cluster activity, usual ...
Ultrastructural Characterization of Gerbil Olivocochlear Neurons
Ultrastructural Characterization of Gerbil Olivocochlear Neurons

... olive, are small in size, and receive very few synaptic contacts. The vast majority of these synapses contain small, mildly pleomorphic vesicles with scattered dense core vesicles. Synapses with distinctly larger pleomorphic vesicles have also been observed. These neurons possess all of the features ...
(Title 17, United States Code) governs the maki
(Title 17, United States Code) governs the maki

... 2008). Conversely, animals that do not have to employ these methods for survival do not have modified hippocampal regions. Although the relationship between hippocampal morphology and increased demands through spatial use has been demonstrated in numerous species, it still remains unknown what mecha ...
Paper by Daniel Romer (2010) "Adolescent Risk Taking,Impulsivity
Paper by Daniel Romer (2010) "Adolescent Risk Taking,Impulsivity

... a rise in sensation seeking that results from activation of the ventral striatum (Chambers et al., 2003; Spear, 2009). As already noted, this change encourages experimentation with novel (adult-like) behavior. However, rather than representing a structural deficit in frontal control, these risk-taki ...
Anatomy Lecture 3 Descending Motor Tracts In the last lecture the
Anatomy Lecture 3 Descending Motor Tracts In the last lecture the

... laminae 4,5,6,7,8 and may synapse with the interneurons there. If you “in3’azait be dabboos” you will move your hand away rapidly, why do you do that? This movement is to “fool the brain”. Moving the hand rapidly will cause impulses to flow down from the cortex (area 3,1,2) through the corticospinal ...
Broca`s Area in Language, Action, and Music
Broca`s Area in Language, Action, and Music

... Evolutionary Origin of Broca’s Area Neuroanatomic studies of Broca’s area (Fig. 1), and in particular of its pars opercularis (BA44), show that some cytoarchitectonic properties are shared with premotor cortex (BA6). Indeed, the granular cell layer (the IV cortical layer), which is clearly absent in ...
neurons that transmit messages from sensory receptors
neurons that transmit messages from sensory receptors

... the section of cortex that lies in the frontal lobe, just across the central fissure from the sensory cortex. Neural impulses in the motor cortex are linked to muscular responses throughout the body ...
Color Atlas of Neurology
Color Atlas of Neurology

... Reflexes Reflexes are involuntary and relatively stereotyped responses to specific stimuli. Afferent nerve fibers conduct the impulses generated by activated receptors to neurons in the central nervous system, which fire impulses that are then transmitted through efferent nerve fibers to the cells, ...
Cells of the Nervous System
Cells of the Nervous System

... which neurons can communicate with each other. These communications make it possible for circuits of neurons to gather sensory information, make plans, and initiate behaviors via synapses. The primary means of communication between neurons is synaptic transmission—the transmission of messages from o ...
The Matrix Protein Hikaru genki Localizes to Cholinergic Synaptic
The Matrix Protein Hikaru genki Localizes to Cholinergic Synaptic

... (Fig. 1I). These immunohistochemical data from antennal lobe, MB, and other brain regions, including the optic lobes (see Fig. 3 A, B), indicated that Hig predominantly localized to cholinergic synapses in the brain. To further analyze the discrete pattern of Hig in the microglomeruli, brains were s ...
Protein Modeling Challenge Science Olympiad Trial Event
Protein Modeling Challenge Science Olympiad Trial Event

... RasMol is a great program and may be continued to be used by Science Olympiad Teams. However, since there have not been updates to RasMol to allow for it to operate easily on Macs, Jmol will be the computer visualization program to be used in the future. The commands that you have used in RasMol are ...
STOCHASTIC GENERATION OF BIOLOGICALLY - G
STOCHASTIC GENERATION OF BIOLOGICALLY - G

... these neurons into a web-based database of synthetic brain microstructure. This is the direct (or synthetic) brain construction process. We can then turn the table to the indirect (or reciprocal ) process, and develop algorithms to find basic circuits directly from the web-based database of syntheti ...
Malformations of Cortical Development (MCD): Genetic Aspects
Malformations of Cortical Development (MCD): Genetic Aspects

... neuronal migration disorders (NMDs) causing severe, global neurological impairment. Abnormalities of the LIS1, DCX, ARX, RELN genes have been associated with these malformations. Recent work has also established a relationship of lissencephaly, with or without associated microcephaly, corpus callosu ...
A chemogenomic analysis of the transmembrane binding cavity of
A chemogenomic analysis of the transmembrane binding cavity of

... GPCRs5 and opens a new avenue for drug discovery, especially with respect to the 100 orphan receptors for which even the endogenous ligand still has not been characterized.6 Historically, GPCRs have been classified according to the chemical nature of their ligands, their specificity for known agonists ...
W3005 1/29/0 Prof
W3005 1/29/0 Prof

... formation of specific connections between nerve cells, the basic “wiring diagram” of the brain. Navigation results in an initial mapping of neurons to their targets; synaptic connections are further refined by experience (activity). Mutants that are deficient axon migration are neurologically abnorm ...
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Clinical neurochemistry



Clinical neurochemistry is the field of neurological biochemistry which relates biochemical phenomena to clinical symptomatic manifestations in humans. While neurochemistry is mostly associated with the effects of neurotransmitters and similarly-functioning chemicals on neurons themselves, clinical neurochemistry relates these phenomena to system-wide symptoms. Clinical neurochemistry is related to neurogenesis, neuromodulation, neuroplasticity, neuroendocrinology, and neuroimmunology in the context of associating neurological findings at both lower and higher level organismal functions.
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