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Mechanisms of response homeostasis during retinocollicular map
Mechanisms of response homeostasis during retinocollicular map

... bidirectional control of intrinsic excitability. Recently, we showed that the total synaptic input onto individual neurons of the mouse superior colliculus is preserved regardless of the size of their visual receptive fields, a phenomenon we term ‘response homeostasis’. Here, we argue that regulatin ...
A Beginner`s Guide to the Mathematics of Neural Networks
A Beginner`s Guide to the Mathematics of Neural Networks

... membrane potential and ring state). Right: close-up of a typical synapse. decrease. In the rst case the arriving signal will increase the probability of the receiving neuron to start ring itself, therefore such a synapse is called excitatory. In the second case the arriving signal will decrease t ...
Progress Report – Glover
Progress Report – Glover

... With the anatomical mapping already in hand, it is feasible to begin asking questions about the genetic regulation of neuronal type specification. As a first step, it is important to determine which transcription factors are expressed in or near specific identified neurons. To this end, Søviknes has ...
Self-images in the video monitor coded by monkey intraparietal
Self-images in the video monitor coded by monkey intraparietal

... a neuron responded to the moving visual stimuli. Tooluse induced an expansion of the visual receptive field only when monkeys intended to use tools to retrieve distant objects, but the modification was never induced when just holding it as an external object. Thus, this modification was not related ...
Engineering new synaptic connections in the C. elegans connectome
Engineering new synaptic connections in the C. elegans connectome

... identified circuits and from molecular characterization of individual mapped synapses.7 However, observation and mapping are not sufficient; in addition, an engineering approach, similar to that underlying synthetic biology, whereby individual biological components are artificially reassembled or co ...
Sparse Coding in the Neocortex
Sparse Coding in the Neocortex

... al. 2005). However, those promoting the usefulness of sparse representations are not proposing that the ultimate goal is to have one neuron for every object—and certainly not for a particular view of every object. We believe that sparseness helps learning and prediction even at early stages of senso ...
Article  - Dynamic Connectome Lab
Article - Dynamic Connectome Lab

... the layers above and below the soma, while the LFP magnitude is largest in the soma layer and decreases in the layers above and below the soma. The differences between the results for the L4 spiny stellate models are small, so we concentrate on the pyramidal neuron population results. For the L2/3 p ...
A comparison of the distribution and morphology of ChAT
A comparison of the distribution and morphology of ChAT

... ABSTRACT: Present knowledge concerning the organization of cholinergic structures of the spinal cord has been derived primarily from studies on small laboratory animals, while there is a complete lack of information concerning its structure in the pig. In the present study we employed choline acetyl ...
Combinatorial Marking of Cells and Organelles with Split
Combinatorial Marking of Cells and Organelles with Split

... HSN fluorescence was weak and rarely seen when split GFP was generated from these promoters ...
Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral Sclerosis (ALS)

A double-edged sword: producing repetitions and prolongations
A double-edged sword: producing repetitions and prolongations

... • A perception / production link appears to exist in the inhibition of stuttering. – Sensory and motoric forms of stuttering inhibition may be related. ...
EN Sokolov`s Neural Model of Stimuli as Neuro
EN Sokolov`s Neural Model of Stimuli as Neuro

... and react to certain physical impacts of stimuli as signals. Receptors are in turn associated with selective detectors – neurons selectively responding to certain stimuli – and this connection can be either direct or, as shown, mediated by the predetectors. Selective detectors operate by the followi ...
Encoding of Movement Fragments in the Motor Cortex
Encoding of Movement Fragments in the Motor Cortex

... Figure 1. Evidence for trajectory encoding in the motor cortex. A, Temporal evolution of preferred directions (in 50 ms bins) for four MI neurons relative to movement onset computed in an instructed-delay center-out task to one of eight targets. B, Left, Example of a single successful behavioral tri ...
The neuronal structure of the substantia nigra in the guinea pig
The neuronal structure of the substantia nigra in the guinea pig

... cell bodies, number and arborisation of dendrites and the dendritic fields. The neuronal structure of SN was also investigated in primates [13,34,35,50], rat [7,23] and kitten [33]. In the primates, Siddiqi and Peters [35] distinguished three types of SN neurons: large multipolar, medium-sized bipol ...
Decoding Complete Reach and Grasp Actions from Local Primary
Decoding Complete Reach and Grasp Actions from Local Primary

Discussion and future directions
Discussion and future directions

... Put generally, it demonstrates that a self–organizing map can learn to distinctively represent and command 12 directions of movement, by extracting the similarity relationships from the input space. The success of the self–organization process is dependent on two factors: the input patterns and the ...
No Slide Title - Computer Science Home
No Slide Title - Computer Science Home

... • Brain is superior in performing pattern recognition, perception, and motor control), e.g., it takes a brain 100-200 msec to recognize a familiar face embedded in an unfamiliar scene (will take days for the computer to do the similar tasks) ...
Neurons in Anterior Cingulate Cortex Multiplex
Neurons in Anterior Cingulate Cortex Multiplex

... The available data do not discriminate whether ACC represents abstract reward information only or more specific information linking particular actions to outcomes because the selectivity of ACC neurons for specific actions remains almost entirely unknown. To address these questions, we probed the ac ...
characterisation of dopamine neurons of the murine ventral
characterisation of dopamine neurons of the murine ventral

... neurons originating from this region project and receive input from various other brain regions and through several neurotransmitter systems. The attention was concentrated on the excitatory modulation suggested to regulate important functions of synaptic plasticity, which have been associated with ...
reciprocal inhibition in the motor nervous system of the nematode
reciprocal inhibition in the motor nervous system of the nematode

... Anatomical studies have shown that this dorsal process can be divided into two distinct regions. The region proximal to the commissure makes numerous neuromuscular synapses and overlaps the processes of two VI dendrites. Anterior to this there is a region where neuromuscular synapses are rare (A. 0. ...
Starosta, S., Güntürkün, O., Stüttgen, M.C., Stimulus
Starosta, S., Güntürkün, O., Stüttgen, M.C., Stimulus

Microinfusion of bupropion inhibits putative GABAergic ventral
Microinfusion of bupropion inhibits putative GABAergic ventral

Phase IIB / PHGY 825 Organization of the Brain Stem Organization
Phase IIB / PHGY 825 Organization of the Brain Stem Organization

Gee JNeuro 2012 - Stanford University
Gee JNeuro 2012 - Stanford University

... in the PFC. To answer this question, we recorded from visually identified neuneurons in neocortex can be divided into at least two subpopurons expressing fluorescent proteins under control of promoters lations, “thick-tufted” neurons that project to thalamus or brainfor D1Rs or D2Rs (Fig. 3A). Speci ...
Action potential
Action potential

... Divisions of the Nervous System  The Peripheral Nervous System (PNS)  Includes all neural tissue outside the CNS  Functions of the PNS  Deliver sensory information to the CNS  Carry motor commands to peripheral tissues and ...
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Mirror neuron

A mirror neuron is a neuron that fires both when an animal acts and when the animal observes the same action performed by another. Thus, the neuron ""mirrors"" the behavior of the other, as though the observer were itself acting. Such neurons have been directly observed in primate species. Birds have been shown to have imitative resonance behaviors and neurological evidence suggests the presence of some form of mirroring system. In humans, brain activity consistent with that of mirror neurons has been found in the premotor cortex, the supplementary motor area, the primary somatosensory cortex and the inferior parietal cortex.The function of the mirror system is a subject of much speculation. Many researchers in cognitive neuroscience and cognitive psychology consider that this system provides the physiological mechanism for the perception/action coupling (see the common coding theory). They argue that mirror neurons may be important for understanding the actions of other people, and for learning new skills by imitation. Some researchers also speculate that mirror systems may simulate observed actions, and thus contribute to theory of mind skills, while others relate mirror neurons to language abilities. Neuroscientists such as Marco Iacoboni (UCLA) have argued that mirror neuron systems in the human brain help us understand the actions and intentions of other people. In a study published in March 2005 Iacoboni and his colleagues reported that mirror neurons could discern if another person who was picking up a cup of tea planned to drink from it or clear it from the table. In addition, Iacoboni has argued that mirror neurons are the neural basis of the human capacity for emotions such as empathy.It has also been proposed that problems with the mirror neuron system may underlie cognitive disorders, particularly autism. However the connection between mirror neuron dysfunction and autism is tentative and it remains to be seen how mirror neurons may be related to many of the important characteristics of autism.Despite the excitement generated by these findings, to date, no widely accepted neural or computational models have been put forward to describe how mirror neuron activity supports cognitive functions such as imitation. There are neuroscientists who caution that the claims being made for the role of mirror neurons are not supported by adequate research.
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