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Gnostic cells in the 21st century
Gnostic cells in the 21st century

... though unknown Russian neurosurgeon, who completely erased the concept of “mother” from a subject’s brain by ablating each and every single of the several thousand neurons representing it (Barlow 1994, Gross 2002). However, after a first moment of exultation, Akakhievitch reasoned that the concept o ...
Dynamic Computation in a Recurrent Network of Heterogeneous
Dynamic Computation in a Recurrent Network of Heterogeneous

... freely bt asacrificed low-level details that are known to affect cluster their local recurrent feedback. One intriguing possibility is dynamics (e.g., they replace spiking with rate-based equathat the interactions between spatio-temporal input patterns tions) [4], and have explored only a handful of ...
Therapeutic Restoration of Spinal Inhibition via
Therapeutic Restoration of Spinal Inhibition via

... (GABAARs) are ligand-gated chloride (Cl−) channels whose effect on membrane potential (Vm) depends on intracellular Cl− concentration ([Cl−]i). When GABAAR channels are opened, the Vm is pulled toward the Cl− equilibrium potential (ECl), which is determined by [Cl−]i and the extracellular Cl− concen ...
Michael Arbib: CS564 - Brain Theory and Artificial Intelligence
Michael Arbib: CS564 - Brain Theory and Artificial Intelligence

... Michael Arbib: CS564 - Brain Theory and Artificial Intelligence University of Southern California, Fall 2001 ...
PDF 2
PDF 2

... model of the disease. Metabolic imaging and electrophysiological studies in the MPTP model have demonstrated that neuronal discharge is increased in the STN, GPi, and SNr but decreased in the GPe. These findings prompted the development of a model in which dopamine depletion leads to (1) increased a ...
Slide 1
Slide 1

... • A main motivation behind neural networks is the fact that symbolic rules do not reflect reasoning processes performed by humans. • Biological neural systems can capture highly parallel computations based on representations that are distributed over many neurons. • They learn and generalize from tr ...
The role of Pitx3 in survival of midbrain dopaminergic neurons
The role of Pitx3 in survival of midbrain dopaminergic neurons

... mDA development have identified several key transcription factors, including Nurr1, Lmx1b and En1=En2, with a function in specification of transmitter identity, neuronal identity and survival of mDA neurons (Smidt et al., 2004a; Perlmann and WallenMackenzie, 2004; Simon et al., 2004). The paired-like ...
Neural network
Neural network

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Motor System: Reflexes, Pyramidal Tract and Basal Ganglia
Motor System: Reflexes, Pyramidal Tract and Basal Ganglia

... inhibitory interneurons in ventral horn, which project across midline to activate or inhibit interneurons, resulting in activation of extensor and inhibition of flexor motor neurons ...
Neural Network for Winner take All Competition using Palm Print
Neural Network for Winner take All Competition using Palm Print

... Assistant Professor, Dept of CSE, SNS College of Engineering, CBE-107, TamilNadu, India. UG Scholar, Dept of CSE, SNS College of Engineering, CBE-107, TamilNadu, India. ...
NIPS/Dec99/notebook3
NIPS/Dec99/notebook3

... and GABAergic interneurons similarly distributed throughout the DCN and expressing different subtypes of glutamatergic receptors. The consequences of interneuronal inhibition by the cerebral cortex are functionally important because the cortical inhibition of inhibitory interneurons that, in turn, s ...
Circuits and Circuit Disorders of the Basal Ganglia
Circuits and Circuit Disorders of the Basal Ganglia

... model of the disease. Metabolic imaging and electrophysiological studies in the MPTP model have demonstrated that neuronal discharge is increased in the STN, GPi, and SNr but decreased in the GPe. These findings prompted the development of a model in which dopamine depletion leads to (1) increased a ...
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PDF file

... for an interactive integration of top-down attention (both position-based and object-based) and recognition. Rather than the simulations of fMRI data, the engineering performance of recognition rate and attended spatial locations are presented in the experiment. However, the bottom-up featurebased a ...
Analysis of Firing Correlations Between Sympathetic Premotor
Analysis of Firing Correlations Between Sympathetic Premotor

... premotor neurons in vivo demonstrate that under normal experimental conditions, action potentials in sympathetic premotor neurons invariably arise from depolarizing events with the characteristics of excitatory synaptic inputs (Lipski et al. 1996). The observation, in the rat, that blockade of excit ...
Neurons and Neurotransmission with Nerve slides
Neurons and Neurotransmission with Nerve slides

... more likely that the receiving neuron will generate an action potential (impulse) •The second neuron is more likely to fire. ...
LESSON 3.3 WORKBOOK
LESSON 3.3 WORKBOOK

... Note that these channels are different from the voltage-gated sodium and calcium channels we talked about on the axon and the presynaptic terminal because they are stimulated to open by a neurotransmitter binding to its receptor, and not by a change in voltage. When channels open that are permeable ...
Forea Wang
Forea Wang

... system offers to fulfill the promise of controlled, multi-site stimulation in patterns that have not only a temporal component, but also a spatial one, and the integration of inputs from multiple cells in tandem can be investigated. Part of the UROP will involve dynamic discussions on how to design ...
download file
download file

... agreement and disagreement. It should be noted at the outset that the level of agreement was high. Each member had made independently subtle shifts from the traditional views of their respective areas, leading to the resolution of previously disparate opinions between different disciplines. The con ...
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Jukic et al. SUPPLEMANTARY SUPLEMENTARY METHODS En1+/

... monoaminergic neurons rather than in their migration or projection (Brodski, et al 2003), only studies that report this aspect of development were taken into consideration. Based on these publications a gene list was compiled for DA as well as for 5-HT neurons. ...
November 29
November 29

... Sleep cycles (REM and other sleep stages) ...
Unsupervised models and clustering
Unsupervised models and clustering

... Selforganizing networks  1 In the central nervous system, the ganglion cells, which constitute the output stage of the retina, are organized according to receptive fields, sensitive to particular stimuli In the auditory system cortex, neurons and fibers are anatomically arranged in an orderly man ...
High-speed CCD movie camera with random pixel selection,
High-speed CCD movie camera with random pixel selection,

... Laser-scanning systems for voltage-sensitive dye recording have been developed by two groups (Morad et al., 1986; Saggau, 1994). These employ acousto-optic deflectors to rapidly steer a laser excitation spot to user- selectable regions in the specimen. Fluorescence is detected by a single photodiode ...
Remembering or Forgetting: The Lifetime of Memories
Remembering or Forgetting: The Lifetime of Memories

... the group improves memory while removing them accelerates forgetting. A special type of neuron in the brain controls the size of these groups. We think that this process regulates the lifetime of memories. ...
Emergence of Sense-Making Behavior by the Stimulus Avoidance
Emergence of Sense-Making Behavior by the Stimulus Avoidance

... to study potential memory and learning by nervous systems. Using the real biological neural networks is advantageous in that, for example, we can study potential complexity, which may be difficult to implement in artificial neural networks. In this study, we use a dissociated cultured neural system ...
Unsupervised models and clustering.
Unsupervised models and clustering.

... Selforganizing networks  1 In the central nervous system, the ganglion cells, which constitute the output stage of the retina, are organized according to receptive fields, sensitive to particular stimuli In the auditory system cortex, neurons and fibers are anatomically arranged in an orderly man ...
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Neural oscillation



Neural oscillation is rhythmic or repetitive neural activity in the central nervous system. Neural tissue can generate oscillatory activity in many ways, driven either by mechanisms within individual neurons or by interactions between neurons. In individual neurons, oscillations can appear either as oscillations in membrane potential or as rhythmic patterns of action potentials, which then produce oscillatory activation of post-synaptic neurons. At the level of neural ensembles, synchronized activity of large numbers of neurons can give rise to macroscopic oscillations, which can be observed in the electroencephalogram (EEG). Oscillatory activity in groups of neurons generally arises from feedback connections between the neurons that result in the synchronization of their firing patterns. The interaction between neurons can give rise to oscillations at a different frequency than the firing frequency of individual neurons. A well-known example of macroscopic neural oscillations is alpha activity.Neural oscillations were observed by researchers as early as 1924 (by Hans Berger). More than 50 years later, intrinsic oscillatory behavior was encountered in vertebrate neurons, but its functional role is still not fully understood. The possible roles of neural oscillations include feature binding, information transfer mechanisms and the generation of rhythmic motor output. Over the last decades more insight has been gained, especially with advances in brain imaging. A major area of research in neuroscience involves determining how oscillations are generated and what their roles are. Oscillatory activity in the brain is widely observed at different levels of observation and is thought to play a key role in processing neural information. Numerous experimental studies support a functional role of neural oscillations; a unified interpretation, however, is still lacking.
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