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Nervous System
Nervous System

... The chemical messages are sent towards the cell body (in other words, dendrites are receivers) ...
Lipid solubility Degree of vascularity of the tissue
Lipid solubility Degree of vascularity of the tissue

... Because of this shift of positive ions out of the centre, the centre is now negative There is a 60-70mV potential across the cell membrane due to these ions Stimuli like a surgeon’s cut are converted into minuscule electric currents - making the area around receptor sites LESS nega ...
File
File

... an axon and is generated by the movement of positively charged atoms in and out of channels in the axon’s membrane. Threshold: The level of stimulation required to trigger the action potential ...
Nerves, Hormones, and Homeostasis
Nerves, Hormones, and Homeostasis

... nervous system (CNS) and peripheral nerves, and is composed of cells called neurons that can carry rapid electrical impulses. • 6.5.2-Draw and label the structure of a motor neuron. • 6.5.3-State that nerve impulses are conducted from receptors to the CNS by sensory neurons, within the CNS by relay ...
File
File

... neurotransmitter binds to a receptor that is not part of an ion channel. • This binding activates a signal transduction pathway involving a second messenger in the postsynaptic cell. • Effects of indirect synaptic transmission have a ...
Lecture #13 – Animal Nervous Systems
Lecture #13 – Animal Nervous Systems

... • Neuron resting potential is ~ -70mV At resting potential the neuron is NOT actively transmitting signals Maintained largely because cell membranes are more permeable to K+ than to Na+; more K+ leaves the cell than Na+ enters An ATP powered K+/Na+ pump continually restores the concentration grad ...
“Put that in the Form of a Question, Please!”
“Put that in the Form of a Question, Please!”

... inside (Na+ ions more prevalent on outside). When in action potential, polarity switches and cell becomes more positive on inside as ion channels open up and Na+ ions flood in? ...
Synapses - Franklin College
Synapses - Franklin College

... Two neurons releasing neurotransmitters that act on a third neuron. The first two neurons could be in the Central Nervous System, and the third might be a motor neuron leading out to a muscle or gland. Schwann Cells form a myelin sheath Around the axon of motor neurons Neurons ...
Communication within the Nervous System
Communication within the Nervous System

... between the inside and outside of the membrane of a neuron at rest. • Between -40 and -80 millivolts (mV) in different ...
What is the cause of the changes in membrane potential during an
What is the cause of the changes in membrane potential during an

... Shapes and timing of the action potentials Conduction of the action potential Components within the compound action potential • Refractory period/Faithfulness of conduction ...
Action Potential
Action Potential

... approximately -100 mV - positive outside and negative inside. ...
D. Vertebrate Nervous Systems
D. Vertebrate Nervous Systems

...  Gated Na+ channels open Na+ diffuses into the cell the membrane potential becomes less negative.  The Action Potential: All or Nothing Depolarization.  If graded potentials sum to -55mV a threshold potential is achieved.  This triggers an action potential.  Axons only.  In the resting state ...
Neurons, Synapses, and Signaling
Neurons, Synapses, and Signaling

... • Graded potentials are changes in polarization where the magnitude of the change varies with the strength of the stimulus • These are not the nerve signals that travel along axons, but they do have an effect on the generation of nerve signals • If a depolarization shifts the membrane potential suff ...
Terms being described
Terms being described

... 11. It’s another name for motor neurons because of their direction of conduction. 13. It’s another name for sensory neurons because of their direction of conduction. 15. It’s the ability of a potential change to spread along the axon that is analogous to the conduction of electricity by a wire. 17. ...
Nervous System
Nervous System

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axon - the long extension of a neuron that carries nerve impulses
axon - the long extension of a neuron that carries nerve impulses

... measure the potential energy (about -70 millivolts), like a tiny battery. When the neuron is stimulated, sodium ions can enter the cell. The potential energy (voltage) across the membrane drops. Even though the cell membrane quickly begins to restore the ions to their proper position, this change, i ...
Tutorial 9: Excitatory Postsynaptic Potentials Figure 9: Excitatory
Tutorial 9: Excitatory Postsynaptic Potentials Figure 9: Excitatory

... development, structure, and function of the dendritic trees of neurons and the postsynaptic membranes that define them. These scientific ventures include the study of plastic (changeable) features of developing and mature postsynaptic structures and their response to stimulation (Segal, Korkotian & ...
week4am
week4am

...  Other terms – spike, firing, generating an AP ...
Neurons and the Nervous System
Neurons and the Nervous System

... Action potentials are the signals conducted by axons •  Changes in membrane potential occur because neurons contain gated ion channels that open or close in response to stimuli •  When gated K+ channels open, K+ diffuses out, making the inside of the cell more negative •  This is hyperpolarization, ...
Neural Control - Del Mar College
Neural Control - Del Mar College

... A Sodium–potassium pumps actively transport 3 Na+ out of a neuron for every 2 K+ they pump in. ...
Chapter 12 - FacultyWeb Support Center
Chapter 12 - FacultyWeb Support Center

... 4. As sodium ions rush into the cell, the membrane potential changes and temporarily becomes _____________ on the inside. 5. When sodium channels close and potassium channels open, _____________ diffuses out across the membrane and the inside of the membrane becomes negatively charged again. 6. Repo ...
Lecture #13 – Animal Nervous Systems
Lecture #13 – Animal Nervous Systems

... • Neuron resting potential is ~ -70mV At resting potential the neuron is NOT actively transmitting signals Maintained largely because cell membranes are more permeable to K+ than to Na+; more K+ leaves the cell than Na+ enters An ATP powered K+/Na+ pump continually restores the concentration grad ...
File
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... resting potential clip ...
Neuronal Signaling
Neuronal Signaling

... - Decreases time to charge the nearby membrane, increasing conduction velocity - Myelin increases the passive conduction distance (remember that larger Rm increases the length constant, lambda) - Myelin decreases the time to charge the membrane by decreasing Cm ...
What does this data figure show?
What does this data figure show?

... 1) Channels that allow the passive flow of ions across the membrane and enable the suppression of responses to inputs that occur at high frequencies. 2) Voltage-gated ion channels that oppose changes to the membrane potential and suppress responses to inputs that occur at ...
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Action potential



In physiology, an action potential is a short-lasting event in which the electrical membrane potential of a cell rapidly rises and falls, following a consistent trajectory. Action potentials occur in several types of animal cells, called excitable cells, which include neurons, muscle cells, and endocrine cells, as well as in some plant cells. In neurons, they play a central role in cell-to-cell communication. In other types of cells, their main function is to activate intracellular processes. In muscle cells, for example, an action potential is the first step in the chain of events leading to contraction. In beta cells of the pancreas, they provoke release of insulin. Action potentials in neurons are also known as ""nerve impulses"" or ""spikes"", and the temporal sequence of action potentials generated by a neuron is called its ""spike train"". A neuron that emits an action potential is often said to ""fire"".Action potentials are generated by special types of voltage-gated ion channels embedded in a cell's plasma membrane. These channels are shut when the membrane potential is near the resting potential of the cell, but they rapidly begin to open if the membrane potential increases to a precisely defined threshold value. When the channels open (in response to depolarization in transmembrane voltage), they allow an inward flow of sodium ions, which changes the electrochemical gradient, which in turn produces a further rise in the membrane potential. This then causes more channels to open, producing a greater electric current across the cell membrane, and so on. The process proceeds explosively until all of the available ion channels are open, resulting in a large upswing in the membrane potential. The rapid influx of sodium ions causes the polarity of the plasma membrane to reverse, and the ion channels then rapidly inactivate. As the sodium channels close, sodium ions can no longer enter the neuron, and then they are actively transported back out of the plasma membrane. Potassium channels are then activated, and there is an outward current of potassium ions, returning the electrochemical gradient to the resting state. After an action potential has occurred, there is a transient negative shift, called the afterhyperpolarization or refractory period, due to additional potassium currents. This mechanism prevents an action potential from traveling back the way it just came.In animal cells, there are two primary types of action potentials. One type is generated by voltage-gated sodium channels, the other by voltage-gated calcium channels. Sodium-based action potentials usually last for under one millisecond, whereas calcium-based action potentials may last for 100 milliseconds or longer. In some types of neurons, slow calcium spikes provide the driving force for a long burst of rapidly emitted sodium spikes. In cardiac muscle cells, on the other hand, an initial fast sodium spike provides a ""primer"" to provoke the rapid onset of a calcium spike, which then produces muscle contraction.
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