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Ppt
Ppt

... More Na+ leave the cell than K+ enter. Charge difference of -70mv across membrane Inside of axon is negative compared to the outside. ...
Chapter 12: Neural Tissue
Chapter 12: Neural Tissue

... Local graded potentials, originating on cell dendrites or cell bodies, trigger specific cell functions (such as exocytosis of glandular secretions or ACh at a motor end plate) at the synaptic terminals of axons. The link between the two actions is the action potential. ...
AP Biology Campbell 8th Edition Chapter 1 Study Guide
AP Biology Campbell 8th Edition Chapter 1 Study Guide

... ** If this is not printed in color, it is suggested you color code the ion channels and ions as you go through this topic. Ions channels and ions should be color coded as follows: Red: Sodium ion channels and sodium ions Blue: Potassium ion channels and potassium ions Introduction • Neurons communic ...
Heather is going to be talking to you about simulations of the brain
Heather is going to be talking to you about simulations of the brain

... rapidly flip from being negative (-65 mV) to being positive (+40 mV). This rapid change in potential, or depolarization, is known as an action potential. 19. The neuron at rest is quite negative, as I mentioned. But, if the permeability of the cell membrane is altered, then positive ions can rush in ...
Midterm 1 - studyfruit
Midterm 1 - studyfruit

... ● Estimated that it expends as much as 70% of the total amount of ATP used by the brain Calcium pump is an enzyme that actively transports Ca++ out of the cytosol across the cell membrane An equilibrium potential for an ion is the membrane potential that results if a membrane is selectively permeabl ...
Chapter 12: Neural Tissue
Chapter 12: Neural Tissue

... – All stimuli that exceed threshold will produce identical action potentials ...
Document
Document

... • The membrane is electrically charged, “polarized” due to Na+ and K+ ions o Greater concentration of sodium ions outside and potassium ions inside. o Potassium ions pass through more easily o Active transport (sodium/potassium pump) maintains balance ...
electrochemical impulse
electrochemical impulse

... the membrane has sodium ion channels embedded within it. As the sodium gates open, the potassium gates close. This allows for the rapid flow of sodium ions into the cell, causing a charge reversal which is referred to as depolarization. ...
Chem*3560 Lecture 31: Ion selective channels
Chem*3560 Lecture 31: Ion selective channels

... to create a voltage spike or action potential which is the basis of transmission of nerve impulses. Gating is therefore important to ensure opening occurs only on the required signal. Rapid closure of the gate ensures that there is not too much dissipation of the overall Na+ and K+ gradients (which ...
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Effect of Nm blockers on Frog Rectus Abdomens Muscle

... B. Depolarizing : e.g. suxamethonium ...
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... and becomes a little more negative than Resting potential. Slowly RMP is reestablished to = -70mV. ...
Chapter 9 Joints - Dr. Jerry Cronin
Chapter 9 Joints - Dr. Jerry Cronin

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YF-MA12056 anti-alpha 3 Sodium Potassium ATPase

... alpha 3 Sodium Potassium ATPase (-, 879 a.a. ~ 985 a.a) partial recombinant protein with GST tag. Clonality ...
ch12-nervous-tissue
ch12-nervous-tissue

... E. 12.4 Electrophysiology of neurons--electrophysiology of neurons especially resting, local, and action potentials; Understand Figures 12.11-15; Table 12.2 on page 456 is very important  Complete the following table. Local potential Action potential Graded—proportional to stimulus strength ...
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File

... Movement of Action Potential Many action potentials are generated one after another along the cell membrane, causing a wave of depolarization (similar to falling dominos).  When axons are myelinated, nerve impulses travel by saltatory conduction ...
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... Histology of Nervous Tissue 2 cell types: • Neurons transmit nerve impulses • Neuroglia: support neurons ...
Reflex Arc - TangHua2012-2013
Reflex Arc - TangHua2012-2013

... myelinated axons and dendrites, the ____________________________________________. In unmyelinated fibers, the impulse ______________________________________. This difference in speed is because the action potential is ______________________________. ...
Nervous System Review ANSWERS File
Nervous System Review ANSWERS File

... E. Resting potential B. Repolarization C. Action potential 40. Which statement is NOT true about the development of an action potential? A. There is a rapid change in polarity from about -65mV to about + 40 mV B. It can be produced by an electric shock or a sudden change in pH C. The action potentia ...
Ch 3 Review
Ch 3 Review

... The Nerve Impulse cont’d…  Messages received from other neurons alter the resting potential.  If the resting potential changes enough, the cell reaches its threshold, or trigger point, for firing.  The threshold for human neurons is approx -50 ...
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1. What type of joint do the capitulum of the humerus

... 48. Neurotransmitter can be removed from a synaptic cleft by ...
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... Steroid hormones affect the activity of certain proteins within the cell, whereas peptide hormones directly affect the processing of mRNA. Steroid hormones affect the synthesis of proteins to be exported from the cell, whereas peptide hormones affect the synthesis of proteins that remain in the cell ...
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... movement of about 3 ionic charges  Also measure using asymmetry of positive and negative pulses, so may be called asymmetry current ...
Lecture12 PPT
Lecture12 PPT

... • Two processes are responsible for the unequal distribution of ions across the membrane of resting neurons: 1. The differential permeability of the membrane to the ions. The membrane contains ion channels that allow ions to pass through the membrane. The membrane is most permeable to K+ and Cl-, a ...
nervous system - Doctor Jade Main
nervous system - Doctor Jade Main

... Step 3: Inactivation of Na channels & activation of K channels – as membrane potential passes 0 mV, sodium gates are inactivatedbegin to close – by the time they all close and Na inflow ceases voltage peaks at about +35mV Na channels close & voltage regulated K channels open – both electrical & c ...
Chapter 12: Neural Tissue
Chapter 12: Neural Tissue

... – All stimuli that exceed threshold will produce identical action potentials ...
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Action potential



In physiology, an action potential is a short-lasting event in which the electrical membrane potential of a cell rapidly rises and falls, following a consistent trajectory. Action potentials occur in several types of animal cells, called excitable cells, which include neurons, muscle cells, and endocrine cells, as well as in some plant cells. In neurons, they play a central role in cell-to-cell communication. In other types of cells, their main function is to activate intracellular processes. In muscle cells, for example, an action potential is the first step in the chain of events leading to contraction. In beta cells of the pancreas, they provoke release of insulin. Action potentials in neurons are also known as ""nerve impulses"" or ""spikes"", and the temporal sequence of action potentials generated by a neuron is called its ""spike train"". A neuron that emits an action potential is often said to ""fire"".Action potentials are generated by special types of voltage-gated ion channels embedded in a cell's plasma membrane. These channels are shut when the membrane potential is near the resting potential of the cell, but they rapidly begin to open if the membrane potential increases to a precisely defined threshold value. When the channels open (in response to depolarization in transmembrane voltage), they allow an inward flow of sodium ions, which changes the electrochemical gradient, which in turn produces a further rise in the membrane potential. This then causes more channels to open, producing a greater electric current across the cell membrane, and so on. The process proceeds explosively until all of the available ion channels are open, resulting in a large upswing in the membrane potential. The rapid influx of sodium ions causes the polarity of the plasma membrane to reverse, and the ion channels then rapidly inactivate. As the sodium channels close, sodium ions can no longer enter the neuron, and then they are actively transported back out of the plasma membrane. Potassium channels are then activated, and there is an outward current of potassium ions, returning the electrochemical gradient to the resting state. After an action potential has occurred, there is a transient negative shift, called the afterhyperpolarization or refractory period, due to additional potassium currents. This mechanism prevents an action potential from traveling back the way it just came.In animal cells, there are two primary types of action potentials. One type is generated by voltage-gated sodium channels, the other by voltage-gated calcium channels. Sodium-based action potentials usually last for under one millisecond, whereas calcium-based action potentials may last for 100 milliseconds or longer. In some types of neurons, slow calcium spikes provide the driving force for a long burst of rapidly emitted sodium spikes. In cardiac muscle cells, on the other hand, an initial fast sodium spike provides a ""primer"" to provoke the rapid onset of a calcium spike, which then produces muscle contraction.
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