Case Study Template 1
... the channel, then no mechanism exists to open the channel on the outside so the block has been ‘ratcheted’ through SecY. ...
... the channel, then no mechanism exists to open the channel on the outside so the block has been ‘ratcheted’ through SecY. ...
1 Lecture 15: Molecular Structure of the Cell Membrane 15.1
... From what we have discussed so far, we know that the phospholipid bilayer has a middle part, which has no water – it is a hydrophobic environment. Figure 15.6 is an electron microscope of two cell membranes. Between the cell membranes is the intracellular space. When we look closely at the cell m ...
... From what we have discussed so far, we know that the phospholipid bilayer has a middle part, which has no water – it is a hydrophobic environment. Figure 15.6 is an electron microscope of two cell membranes. Between the cell membranes is the intracellular space. When we look closely at the cell m ...
Lipid peroxidation modifies the assembly of biological membranes
... diverse organelles. MCSs are domains where two membranes come to close proximity, typically less than 30 nm, and create microdomains that favor exchange between two organelles. Since the endoplasmic reticulum (ER) is the most widespread cellular membrane network, it is thus not surprising to find th ...
... diverse organelles. MCSs are domains where two membranes come to close proximity, typically less than 30 nm, and create microdomains that favor exchange between two organelles. Since the endoplasmic reticulum (ER) is the most widespread cellular membrane network, it is thus not surprising to find th ...
Topological characterization of the essential Escherichia coli cell
... Fig. 1. Predicted transmembrane segments of FtsW by di¡erent methods and the predicted and proposed models. A: Open bars represent transmembrane or uncharged segments. The prediction methods DAS, SOSUI, TMpred, TMAP, and pHDtopology are described in the text. The HYDROPHOBIC prediction was obtained ...
... Fig. 1. Predicted transmembrane segments of FtsW by di¡erent methods and the predicted and proposed models. A: Open bars represent transmembrane or uncharged segments. The prediction methods DAS, SOSUI, TMpred, TMAP, and pHDtopology are described in the text. The HYDROPHOBIC prediction was obtained ...
Neuronal Modeling
... membrane potential is referred to as a depolarization, while restoration of the resting potential is termed repolarization ...
... membrane potential is referred to as a depolarization, while restoration of the resting potential is termed repolarization ...
FIGURE LEGENDS FIGURE 5.1 Intracellular recording of the
... K+ ionic pump (also known as Na+, K+-ATPase). Concentrations (in millimoles except that for intracellular Ca2+) of the ions are given in parentheses; their equilibrium potentials (E) for a typical mammalian neuron are indicated. FIGURE 5.3 The equilibrium potential is influenced by the concentration ...
... K+ ionic pump (also known as Na+, K+-ATPase). Concentrations (in millimoles except that for intracellular Ca2+) of the ions are given in parentheses; their equilibrium potentials (E) for a typical mammalian neuron are indicated. FIGURE 5.3 The equilibrium potential is influenced by the concentration ...
Inner nuclear membrane protein transport is mediated by multiple
... The nuclei formed in this assay system can recapitulate many characteristics of interphase, including DNA replication and NE growth [32]. Depletion of p47 was also found to block the growth phase [31]. Although a mechanism clearly exists for vesicle fusion, the dependency on this mechanism observed ...
... The nuclei formed in this assay system can recapitulate many characteristics of interphase, including DNA replication and NE growth [32]. Depletion of p47 was also found to block the growth phase [31]. Although a mechanism clearly exists for vesicle fusion, the dependency on this mechanism observed ...
P215 - Basic Human Physiology
... • response of the nerve cell to the stimulus is “all or none” – Amt of depolarization always the same – differences in stimulus intensity are detected by • The number of neurons undergoing AP in response to the stimulus • The frequency of action potential generation ...
... • response of the nerve cell to the stimulus is “all or none” – Amt of depolarization always the same – differences in stimulus intensity are detected by • The number of neurons undergoing AP in response to the stimulus • The frequency of action potential generation ...
Biology 212: January 30, 2002
... All relevant channels involved, and when they open and close (refer to your “custom drawing” from class) Which ions move when, in which direction, and what they do to the membrane potential 11. Briefly explain how an action potential is propagated down an axon. 12. Describe, step-by-step, what h ...
... All relevant channels involved, and when they open and close (refer to your “custom drawing” from class) Which ions move when, in which direction, and what they do to the membrane potential 11. Briefly explain how an action potential is propagated down an axon. 12. Describe, step-by-step, what h ...
SNX9 – a prelude to vesicle release - Journal of Cell Science
... membrane has developed into a highly invaginated bud, only a narrow membrane neck remains that connects the vesicle to the plasma membrane. The separation of the vesicle from the originating membrane is accomplished by the action of the large GTPase dynamin, which – in a process that is still not fu ...
... membrane has developed into a highly invaginated bud, only a narrow membrane neck remains that connects the vesicle to the plasma membrane. The separation of the vesicle from the originating membrane is accomplished by the action of the large GTPase dynamin, which – in a process that is still not fu ...
lysosomes
... • Also present in the plasma membrane – but not to any extent in other membranes in the cell ...
... • Also present in the plasma membrane – but not to any extent in other membranes in the cell ...
Learning Objectives
... Explain the mechanism of action of acetylcholine in modulating muscle contraction. Give the receptors through which these neurotransmitters carry out these functions. ...
... Explain the mechanism of action of acetylcholine in modulating muscle contraction. Give the receptors through which these neurotransmitters carry out these functions. ...
Cells_and_Tissues__Ch_3__S2015_Part_1
... facilitated specific channel diffusion protein (aquaporin) through a or through the lipid channel protein; bilayer mostly ions, selected on basis of size and charge ...
... facilitated specific channel diffusion protein (aquaporin) through a or through the lipid channel protein; bilayer mostly ions, selected on basis of size and charge ...
Chapter 14
... Ca2+ is transported out of the cell or into the ER lumen, so intracellular Ca2+ concentrations are extremely low. Transient, localized increases in intracellular Ca2+ are important in cell signaling (as in muscle contraction). ...
... Ca2+ is transported out of the cell or into the ER lumen, so intracellular Ca2+ concentrations are extremely low. Transient, localized increases in intracellular Ca2+ are important in cell signaling (as in muscle contraction). ...
Regulation of ion channels
... opening voltage-gated Na+ channels • This causes further depolarization of membrane and opening of additional voltage-gated Na+ channels • Na+ channels in the region of the membrane (green) where the action potential originated remain closed • These channels are refractory to opening by depolarizati ...
... opening voltage-gated Na+ channels • This causes further depolarization of membrane and opening of additional voltage-gated Na+ channels • Na+ channels in the region of the membrane (green) where the action potential originated remain closed • These channels are refractory to opening by depolarizati ...
Side-chain hydrophobicity scale derived from transmembrane
... We used the outer membrane phospholipase A (OmpLA) as a transmembrane scaffold on which to introduce amino acid side chains of our choice at various membrane depths. We selected OmpLA because it: (a) spontaneously folds and inserts into lipid membranes from a solubilized unfolded state (14), (b) has ...
... We used the outer membrane phospholipase A (OmpLA) as a transmembrane scaffold on which to introduce amino acid side chains of our choice at various membrane depths. We selected OmpLA because it: (a) spontaneously folds and inserts into lipid membranes from a solubilized unfolded state (14), (b) has ...
File
... accurately teachcell membrane ing all of the prop accurately teaching oserties of the cell mosis and other forms membrane of passive transport as accurately teachwell as active transport ing osmosis and teaching about how the other forms of pascontent connects to real ...
... accurately teachcell membrane ing all of the prop accurately teaching oserties of the cell mosis and other forms membrane of passive transport as accurately teachwell as active transport ing osmosis and teaching about how the other forms of pascontent connects to real ...
3.3 Cell Membrane Cell membranes are composed of two
... A cell can import and export large materials or large amounts of material in vesicles during the processes of endocytosis and exocytosis. • Cells use energy to transport material in vesicles. • Endocytosis is the process of taking material into the cell. • Phagocytosis is a type of endocytosis. ...
... A cell can import and export large materials or large amounts of material in vesicles during the processes of endocytosis and exocytosis. • Cells use energy to transport material in vesicles. • Endocytosis is the process of taking material into the cell. • Phagocytosis is a type of endocytosis. ...
How Do Plant Mitochondria Avoid Importing Chloroplast Proteins
... apparent and there was an additional protein of around 9 kD. The absence of Tom37 from the plant complex was not so surprising, since this subunit is also missing from the N. crassa complex, and the Tom37 subunit might have a function unique to the mitochondria of yeast (Gratzer et al., 1995) and ma ...
... apparent and there was an additional protein of around 9 kD. The absence of Tom37 from the plant complex was not so surprising, since this subunit is also missing from the N. crassa complex, and the Tom37 subunit might have a function unique to the mitochondria of yeast (Gratzer et al., 1995) and ma ...
Mechanism of polarized lysosome exocytosis in epithelial cells
... Molecular machinery implicated in calcium-induced lysosome exocytosis include the lysosomal calcium sensor synaptotagmin ...
... Molecular machinery implicated in calcium-induced lysosome exocytosis include the lysosomal calcium sensor synaptotagmin ...
Nerve Impulse Transmission
... • The nerve impulse needs to cross this gap and it does so by the release of special chemicals called neurotransmitters. ...
... • The nerve impulse needs to cross this gap and it does so by the release of special chemicals called neurotransmitters. ...
Chapter 12 - Membrane Transport
... concentration) thru a semi-permeable membrane is called Osmosis. Concept: Because solutions are always referred to in terms of concentration of solute, water moves by osmosis to the area of higher solute concentration. Despite the impression that the solutes are “pulling,” or attracting, water, osmo ...
... concentration) thru a semi-permeable membrane is called Osmosis. Concept: Because solutions are always referred to in terms of concentration of solute, water moves by osmosis to the area of higher solute concentration. Despite the impression that the solutes are “pulling,” or attracting, water, osmo ...
SNARE (protein)
SNARE proteins (an acronym derived from ""SNAP (Soluble NSF Attachment Protein) REceptor"") are a large protein superfamily consisting of more than 60 members in yeast and mammalian cells. The primary role of SNARE proteins is to mediate vesicle fusion, that is, the fusion of vesicles with their target membrane bound compartments (such as a lysosome). The best studied SNAREs are those that mediate docking of synaptic vesicles with the presynaptic membrane in neurons. These SNAREs are the targets of the bacterial neurotoxins responsible for botulism and tetanus.