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Tertiary Structure
Tertiary Structure

... 1). All information for folding is contained in the primary sequence. 2). Secondary structure formation is spontaneous - a consequence of the formation of hydrogen bonds. 3). No protein is stable as a single layer - hence secondary structural elements pack together in sheets. 4). Connections between ...
ppt
ppt

...  After an action potential occurs, the membrane cannot be stimulated to undergo another action potential.  This brief period of time (usually a few milliseconds) is called the refractory period of the membrane.  The events that occur in an action potential continue down the length of the axon unt ...
Structure of the Synapse
Structure of the Synapse

... threshold is reached then action potential is initated • Inhibitory ion channels - neuroreceptors are Cl- channels. When Cl- channels open, hyperpolarisation occurs, making action potential less likely • Non channel synapses - neuroreceptors are membrane-bound enzymes. When activated, they catalyse ...
Nervous System
Nervous System

... are decremental Current is quickly dissipated due to the leaky plasma membrane Can only travel over short distances ...
Cell Membrane Proteins.
Cell Membrane Proteins.

... present in surrounding extracellular fluid so that it is readily available Also, a small amount of carbohydrate is stored in the cells to the cell. ...
BOX 11.1 NEURONAL CABLE THEORY AND COMPUTATIONAL
BOX 11.1 NEURONAL CABLE THEORY AND COMPUTATIONAL

... Rushton, 1946), but Rall extended its application to dendrites. Although much of Rall’s work used this equation to analyze voltage changes in simple linear cables, he also applied it to branching cables and showed that it could be used to analyze dendrites with arbitrary branching geometries. Indeed ...
Figure S1. Chloroplast localization and topology of TerC
Figure S1. Chloroplast localization and topology of TerC

... Figure S1. Chloroplast localization and topology of TerC-GFP fusion protein. (a) Protoplasts were isolated from terc-1TerC-GFP. Chlorophyll fluorescence was excited at 450 – 490 nm and the emission was recorded at > 515 nm (Filterset 9, Carl Zeiss, http://microscopy.zeiss.com/microscopy/en_de/servic ...
Linköping University Post Print Imaging phluorin-based probes at hippocampal synapses
Linköping University Post Print Imaging phluorin-based probes at hippocampal synapses

... ~ 5.5). Upon stimulation, vesicles fuse with the plasma membrane, protons are lost and the fluorescence of pHluorin increases as the pH moves to 7.4. This is seen as an upward deflection in the sypHy trace recording the fluorescence of sypHy in a small region over a synaptic bouton. The fluorescence ...
SED4 Encodes a Yeast Endoplasmic Reticulum
SED4 Encodes a Yeast Endoplasmic Reticulum

... vesicle carriers that bud from the membrane of the donor compartment and then fuse with the membrane of the acceptor compartment (Palade, 1975). A general feature of vesicle formation is the recruitment of proteins from the cytoplasm to the membrane for assembly of a coat on the budding vesicle (Pea ...
Carrier Proteins - HCC Learning Web
Carrier Proteins - HCC Learning Web

... plasma membrane. • Phospholipids are amphipathic molecules, containing hydrophobic (fatty acid tails) and hydrophilic (polar head) regions. • A phospholipid bilayer can exist as a stable boundary between two aqueous compartments. © 2014 Pearson Education, Inc. ...
Chapter 11 General Apicomplexan Biology
Chapter 11 General Apicomplexan Biology

... erythrocyte binding antigen exhibit similar structures (Figure 11.4) and are members of a gene family of erythrocyte binding proteins. In particular, the receptor-binding activity has been mapped to a domain in which the cysteine and aromatic amino acid residues are conserved between species. This s ...
Membrane Structure and Function
Membrane Structure and Function

... 4. The concentration of one substance can affect the diffusion of another 5. Diffusion occurs because populations of molecules move randomly, but individual molecules can be directional (moving in a particular direction across a membrane) ...
what lipids do - staging.files.cms.plus.com
what lipids do - staging.files.cms.plus.com

... aqueous phase while the hydrophobic fatty acyl moieties are arranged internally. It is important to recognize that lipids do not dominate the bilayer as proteins, such as enzymes, transport systems or signalling receptors, span or intercalate into the bilayer and take up much of the membrane surface ...
The Plant Secretory Pathway: An Essential
The Plant Secretory Pathway: An Essential

... Intracellular traffic depends on intermediate compartments as well as on a large number of proteins that ensure fidelity and directionality of each traffic route. Among these, soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) are essential proteins for endomembrane ...
Translation - Santa Susana High School
Translation - Santa Susana High School

... • large unit attaches after the union is made completing the initiation complex - translation begins – proteins called initiation factors bring the units together – energy from GTP is used in the formation of the unit ...
Resting Membrane Potentials
Resting Membrane Potentials

... Gated channels, like the open-access pores, are ion-specific. These gated passages are dependent on particular membrane-affecting agents to either open or close the gate. These may be distinct chemicals referred to as ligands. Voltage changes to the potential across the membrane also can alter these ...
CELL MEMBRANES (Cassaret and Doull`s) Toxicants usually pass
CELL MEMBRANES (Cassaret and Doull`s) Toxicants usually pass

... explain these phenomena, specialized transport systems have been identified. These systems are responsible for the transport (both influx and efflux) across cell membranes of many nutrients, such as sugars and amino and nucleic acids, along with some foreign compounds. Based on the sequencing of th ...
The Cell Membrane
The Cell Membrane

... specific channels allow specific material across cell membrane ...
Small GTPases
Small GTPases

... • GEFs (guanine nucleotide exchange factors) increase the rate of nucleotide exchange • GAPs (GTPase-activating proteins) increase the rate of the GTP hydrolysis • GDIs (guanine nucleotide dissociation inhibitors) block the activation ...
Correlation of β-Amyloid Aggregate Size and Hydrophobicity
Correlation of β-Amyloid Aggregate Size and Hydrophobicity

... β-Amyloid Precursor Protein : (~ 695 amino acids) β-APP – an inhibitory molecule that regulates the activity of proteases ...
Kingdoms and Domains
Kingdoms and Domains

... All multicellular and heterotrophic Cells do not have walls Often organized into tissues, organs, and  organ systems ...
Week2
Week2

... Simultaneously, Voltage Gated K+ activation gates OPEN K+ then leaves the cell by diffusing DOWN its concentration gradient ...
Band  3 protein:  structure,  flexibility  and ... Minireview Da  Neng  Wang*
Band 3 protein: structure, flexibility and ... Minireview Da Neng Wang*

... anion exchanger isomers. There is also a protease sensitive site in the region. The existence of a flexible hinge between the two domains helps to explain a long-standing puzzle. Cherry et al. [33] observed that the removal of spectrin and actin from the erythrocyte membrane resulted in little or no ...
introduction
introduction

... • Inhibition in the CNS can be; postsynaptic presynaptic ...
Cell structure and functions - formatted
Cell structure and functions - formatted

... gradient. Such a transport does not require energy as the movement is down the gradient. Passive transport involves either Simple diffusion or involvement of transport proteins. In simple diffusion, molecules e.g. H2O, CO2 and ethanol move across easily because of their small size and/or non polar n ...
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SNARE (protein)



SNARE proteins (an acronym derived from ""SNAP (Soluble NSF Attachment Protein) REceptor"") are a large protein superfamily consisting of more than 60 members in yeast and mammalian cells. The primary role of SNARE proteins is to mediate vesicle fusion, that is, the fusion of vesicles with their target membrane bound compartments (such as a lysosome). The best studied SNAREs are those that mediate docking of synaptic vesicles with the presynaptic membrane in neurons. These SNAREs are the targets of the bacterial neurotoxins responsible for botulism and tetanus.
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