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Leishmania Flagellum
Leishmania Flagellum

... perception [13]. The differentiation from amastigotes to promastigotes and reciprocally requires the successive assembly and disassembly of hundreds of proteins. The dynamics of these processes is tightly regulated and their understanding necessitates the characterization of individual elements. Bin ...
Chapter 03: The Neuronal Membrane at Rest
Chapter 03: The Neuronal Membrane at Rest

... when separated by a phospholipid membrane – Equilibrium reached when K+ channels inserted into the phospholipid bilayer – Electrical potential difference that exactly balances ionic concentration gradient ...
-portal.org Journal of Molecular Biology
-portal.org Journal of Molecular Biology

... synthesis and integration into the membrane are coupled. For the integration of individual TM sequences into the membrane, it is expected that TM segments will preadopt a helical state, 3,4 due to the significant free-energy penalty of embedding an exposed polypeptide backbone into the hydrophobic m ...
6 systems biology of cell organization
6 systems biology of cell organization

... Which Produces a Proteome The genome of every organism contains the information necessary to produce a system of RNA and protein molecules that provides the foundation for cell structure, function, and organization. An important paradigm in biology is that “structure determines function.” The inform ...
Plant and Soil
Plant and Soil

... the plant to the fungus involves passive efflux across the plant plasma membrane followed by active uptake by the fungal plasma membrane from the interfacial apoplast (Figure 1). The nature of the membrane transport proteins that mediate these processes remains still unknown. A cDNA clone encoding a ...
Autophagy in the Eukaryotic Cell - CiteSeerX
Autophagy in the Eukaryotic Cell - CiteSeerX

... Downloaded from http://ec.asm.org/ on February 21, 2013 by PENN STATE UNIV ...
Lecture Outline
Lecture Outline

... action potential to be re-initiated there. This process is repeated over and over again as the action potential travels the length of the axon. o At each position along the axon, the process is identical, such that the shape and magnitude of the action potential remain constant. Immediately behind t ...
Functional Roles Of Lipids In membranes - IJS
Functional Roles Of Lipids In membranes - IJS

... the critical micelle concentration due to the increased hydrophobic effect. However, the larger the polar domain, either because of the size of neutral domains or charge repulsion for ionic domains, the higher the critical micelle concentration due to the unfavorable steric hindrance in bringing the ...
Transport of proteins across mitochondrial membranes
Transport of proteins across mitochondrial membranes

... are incompetent for import of most but not all preproteins, in particular of those containing N-terminal extensions [22]. Mitochondria in the mutant cells have lost the cristae membranes and their membrane bound cytochromes. MOM19 is thus an important although not essential component of the import m ...
Structure of Spin-Coated Lipid Films and Domain Formation in
Structure of Spin-Coated Lipid Films and Domain Formation in

... used for hydrated membranes in water is generally much more gentle for the sample than conventional tapping mode imaging. We have never observed scanner-induced damage to supported membranes when operating in MAC mode. Force-distance measurements were performed in an MFP3D system (Asylum Research, S ...
Detergent-resistant plasma membrane proteome to elucidate
Detergent-resistant plasma membrane proteome to elucidate

... According to protein clustering in microdomain, proteomic and subsequent enzymatic characterizations of DRM fraction from hybrid aspen cells strongly suggested the involvement of DRM in cell wall polysaccharide synthesis (Bessueille et al., 2009). DRM from hybrid aspen was enriched in glucan synthas ...
Neuron Structure and Function
Neuron Structure and Function

... i) Na+ channels move into an inactive state ii) delayed K+ channels open  Inactivating Na+ channels - Na+ channels go to an inactivated state after 1-2 msec after first opening - inactivated = can NOT be reopened - Membrane potential now determined mostly by K+ (same as for resting potential) and m ...
and extra-vesicular ions and membrane associated charges in
and extra-vesicular ions and membrane associated charges in

... qualitative similarities and sometimes major quantitative differences between these two types of models. Keywords: membrane charges; archaea bipolar tetraether lipids; membrane organization; Monte Carlo simulations ...
Structure, prediction, evolution and genome wide studies of membrane proteins
Structure, prediction, evolution and genome wide studies of membrane proteins

... • One less obvious thing is that molecules need to be located at the right place at the right time. One thing that aids this is compartmentalisation, when molecules are kept separated by different kinds of barriers. For instance, the DNA molecule of a cell needs to be located inside the cell, if it ...
Growing Membranes, Sustaining Cells
Growing Membranes, Sustaining Cells

... committed precursor during fatty acid synthesis. As fatty acid breakdown and synthesis are completely separated into two different metabolic compartments—the mitochondrial matrix and the cytosol—the regulation of a single protein, carnitine-palmitoyl transferase 1A (CPT1A), an enzyme bound to the cy ...
C2006/F2402 `07
C2006/F2402 `07

... A-1. You expect emerin to be (a peripheral protein on the cytoplasmic side) (a peripheral protein on the extracellular side) (a single pass protein) (a multipass protein) (can’t predict). A-2. The amino end of emerin is probably: (in the cytoplasm) (in the membrane) (extracellular) (cytoplasmic or e ...
Neurons, Synapses, and Signaling
Neurons, Synapses, and Signaling

... K+ is higher than at rest, so the membrane potential is closer to E K than it is at the resting potential. The K+ channels eventually close, and the membrane potential returns to the resting potential. ...
Thylakoid biogenesis has joined the new era of bacterial cell biology
Thylakoid biogenesis has joined the new era of bacterial cell biology

... membrane. In G. violaceus a clear separation of “orange” membrane fractions accumulating photosystem assembly factors and photosynthetically active “green” patches can be observed (Rexroth et al., 2011). Thus, cyanobacteria appear to have developed an elaborated system of membrane differentiation wh ...
Mitochondrial protein import: from transport pathways to an
Mitochondrial protein import: from transport pathways to an

... Institut für Biochemie und Molekularbiologie, ZBMZ, Universität Freiburg, 79104 Freiburg, Germany BIOSS Centre for Biological Signalling Studies, Universität Freiburg, 79104 Freiburg, Germany ...
mitochondria
mitochondria

... NADH and FADH2, respectively. Most of the energy derived from oxidative metabolism is then produced by the process ofoxidative phosphorylation (discussed in detail in the next section), which takes place in the inner mitochondrial membrane. The high-energy electrons from NADH and FADH2 are transferr ...
Organelle size control – increasing vacuole
Organelle size control – increasing vacuole

... 1988). In absence of polyP, which normally sequesters and osmotically inactivates these amino acids (Dürr et al., 1979), the excess of vacuolar amino acids might create an osmotic pressure that hinders the organelle from fragmenting in YPD-grown vtc mutants. The tendency of vtc1Δ and vtc4Δ cells to ...
Studies on Liver Plasma Membranes of Rats Fed
Studies on Liver Plasma Membranes of Rats Fed

... membranes, livers, and sera is given in Table 3. No marked difference was observed in the fatty acid composition of livers from the 3 groups of animals. However, there was a significant increase (p < 0.05) in the total polyunsaturated fatty acids and a corresponding decrease in total saturated fatty ...
Cochlea and Auditory Pathways
Cochlea and Auditory Pathways

... The nucleus is the source of efferent axons which selectively “tune” the spiral organ for frequency discrimination (e.g., listening to the play of one instrument within an orchestra). (Efferent innervation affects the length of outer hair cells which changes the position of the tectorial membrane wh ...
The role of cytosolic proteins in the insertion of tail
The role of cytosolic proteins in the insertion of tail

... 2007). The well characterized co-translational pathway is, however, not accessible to the large and diverse group of membrane proteins that are classified as tail-anchored (TA) proteins. TA proteins consist of a cytosolic N-terminal domain anchored to the membrane by a single transmembrane domain (T ...
The Plant Journal
The Plant Journal

... pleckstrin-homology (PH) domain (horizontal hatching); a GTPase effector domain (GED, vertical hatching); and two proline-rich domains (PRDs, crossed hatching). The sequence of PRDs is shown with the potential SH3-binding PXXP motif in bold and underlined. CT1 and CT2 represented the C-terminus frag ...
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SNARE (protein)



SNARE proteins (an acronym derived from ""SNAP (Soluble NSF Attachment Protein) REceptor"") are a large protein superfamily consisting of more than 60 members in yeast and mammalian cells. The primary role of SNARE proteins is to mediate vesicle fusion, that is, the fusion of vesicles with their target membrane bound compartments (such as a lysosome). The best studied SNAREs are those that mediate docking of synaptic vesicles with the presynaptic membrane in neurons. These SNAREs are the targets of the bacterial neurotoxins responsible for botulism and tetanus.
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