Interactions of Annexins with the mu Subunits of the Clathrin
... calcium levels are elevated. The “bivalent” ability of many of the annexins to bind to two membranes and form tight contacts between them led to the early suggestion that the annexins may act as “chaperones” of membrane fusion in processes such as exocytosis (3, 4). However, more recent cell biologi ...
... calcium levels are elevated. The “bivalent” ability of many of the annexins to bind to two membranes and form tight contacts between them led to the early suggestion that the annexins may act as “chaperones” of membrane fusion in processes such as exocytosis (3, 4). However, more recent cell biologi ...
Characterization of Vincristine Transport by the Mr 190,000
... can stimulate drug uptake, which suggests that vincristine transport does not necessarily involve a change in redox state or glutathionylation of the protein. Furthermore, vincristine uptake is accompanied by ATP- and drug-dependent accumulation of GSH, which can also be stimulated to a lesser exten ...
... can stimulate drug uptake, which suggests that vincristine transport does not necessarily involve a change in redox state or glutathionylation of the protein. Furthermore, vincristine uptake is accompanied by ATP- and drug-dependent accumulation of GSH, which can also be stimulated to a lesser exten ...
Annexin-Phospholipid Interactions. Functional Implications
... with membranes in a calcium-dependent manner. Although this is true for the vast majority of the members of this family of proteins, some members, such as mammalian annexin A9, do not bind calcium but still are able to interact with biological membranes through different mechanisms. Human annexin A5 ...
... with membranes in a calcium-dependent manner. Although this is true for the vast majority of the members of this family of proteins, some members, such as mammalian annexin A9, do not bind calcium but still are able to interact with biological membranes through different mechanisms. Human annexin A5 ...
Minireview: Lipid Droplets in Lipogenesis and Lipolysis
... the notion that it forms a hormonally regulated barrier between cytosolic lipases and the neutral lipids within. Consistent with this model, heterologous expression of perilipin A in 3T3-L1 preadipocytes leads to increased TAG storage by reducing the rate of TAG hydrolysis rather than by promoting T ...
... the notion that it forms a hormonally regulated barrier between cytosolic lipases and the neutral lipids within. Consistent with this model, heterologous expression of perilipin A in 3T3-L1 preadipocytes leads to increased TAG storage by reducing the rate of TAG hydrolysis rather than by promoting T ...
Aerobic and Anaerobic Bacterial Respiration
... to reduce nitrate when oxygen was available, and equally rapidly commenced nitrate reduction when all the oxygen had been consumed. By contrast, membrane vesicles isolated from P. denitrijicans reduced oxygen and nitrate simultaneously. The respiratory nitrate reductase in intact cells of P. denitri ...
... to reduce nitrate when oxygen was available, and equally rapidly commenced nitrate reduction when all the oxygen had been consumed. By contrast, membrane vesicles isolated from P. denitrijicans reduced oxygen and nitrate simultaneously. The respiratory nitrate reductase in intact cells of P. denitri ...
Mitochondrial Dynamics
... localizes to the inner surface of the cell membrane at division sites, where it forms a ring structure (Z ring) that enables constriction and scission of the parent into two daughter cells. FtsZ is a GTPase, which can hydrolyze guanosine triphosphate to provide a source of energy. However, it is tho ...
... localizes to the inner surface of the cell membrane at division sites, where it forms a ring structure (Z ring) that enables constriction and scission of the parent into two daughter cells. FtsZ is a GTPase, which can hydrolyze guanosine triphosphate to provide a source of energy. However, it is tho ...
The Differential Degradation of Two Cytosolic Proteins As a Tool to
... (1990), who followed sequential steps in autophagy after inducing artificial protein complexes in the ER. However, their observations were restricted to the degradation of these complexes while, in general, autophagy is thought to be a nonspecific process in which cytoplasmic proteins are degraded r ...
... (1990), who followed sequential steps in autophagy after inducing artificial protein complexes in the ER. However, their observations were restricted to the degradation of these complexes while, in general, autophagy is thought to be a nonspecific process in which cytoplasmic proteins are degraded r ...
Nanoscale Architecture of Endoplasmic Reticulum Export Sites and
... chemically fixed higher plant cells (Robinson, 1980; Aniento et al., 2006). The case for tubular connections between ER and Golgi membranes rests on just two publications (Juniper et al., 1982; Harris and Oparka, 1983), which employed chemical fixation and staining protocols that are now known to pr ...
... chemically fixed higher plant cells (Robinson, 1980; Aniento et al., 2006). The case for tubular connections between ER and Golgi membranes rests on just two publications (Juniper et al., 1982; Harris and Oparka, 1983), which employed chemical fixation and staining protocols that are now known to pr ...
Potassium Currents Responsible for Inward and Outward
... (T = RC) of neostriatal cell membranes. Generally. the time constant is measured by making a log plot of the voltage transient evoked by a small amplitude hyperpolarizing current and fitting a line to the linear portion of the response. However, any membrane nonlinearities resulting from voltage-gat ...
... (T = RC) of neostriatal cell membranes. Generally. the time constant is measured by making a log plot of the voltage transient evoked by a small amplitude hyperpolarizing current and fitting a line to the linear portion of the response. However, any membrane nonlinearities resulting from voltage-gat ...
Full Article - PDF - Journal of Biotech Research
... 33, 34]. The inward and outward opening of the pore through the membrane is a major property of MFS transporter family proteins [28]. They have both the N- and C-termini located in the cytoplasmic matrix [35], an observation made for all the proteins studied. In addition, they have extracellular por ...
... 33, 34]. The inward and outward opening of the pore through the membrane is a major property of MFS transporter family proteins [28]. They have both the N- and C-termini located in the cytoplasmic matrix [35], an observation made for all the proteins studied. In addition, they have extracellular por ...
Mitochondrial fusion dynamics is robust in the heart and depends on
... microscopy has shown that acute exercise results in increased structural interactions among mitochondria (29). In addition, elevated Mfn1 and Mfn2 mRNA levels (30), as well as increased mitochondrial continuity (20), have been observed after exercise. Finally, slow-twitch/oxidative fibers that are p ...
... microscopy has shown that acute exercise results in increased structural interactions among mitochondria (29). In addition, elevated Mfn1 and Mfn2 mRNA levels (30), as well as increased mitochondrial continuity (20), have been observed after exercise. Finally, slow-twitch/oxidative fibers that are p ...
LIPIDS
... ranging from 4 to 36 carbons long (C4 to C36). In some fatty acids, this chain is unbranched and fully saturated (contains no double bonds); in others the chain contains one or more double bonds (Table 10–1). A few contain three-carbon rings, hydroxyl groups, or methylgroup branches. A simplified no ...
... ranging from 4 to 36 carbons long (C4 to C36). In some fatty acids, this chain is unbranched and fully saturated (contains no double bonds); in others the chain contains one or more double bonds (Table 10–1). A few contain three-carbon rings, hydroxyl groups, or methylgroup branches. A simplified no ...
Endoplasmic Reticulum Export Sites and Golgi Bodies Behave as
... ER-to-Golgi protein transport may occur in plants. It was proposed that Golgi bodies move between fixed ERES in an actinmyosin–dependent fashion (stop-and-go model; Nebenführ et al., 1999). This model suggests that Golgi bodies become competent for cargo collection once they come to a halt on an ER ...
... ER-to-Golgi protein transport may occur in plants. It was proposed that Golgi bodies move between fixed ERES in an actinmyosin–dependent fashion (stop-and-go model; Nebenführ et al., 1999). This model suggests that Golgi bodies become competent for cargo collection once they come to a halt on an ER ...
The GDP-bound form of Arf6 is located at the plasma membrane
... the T27N and the Q67L mutants, which are thought to be blocked in GDP- and GTP-bound states, respectively. However, these mutants have been poorly characterized biochemically. Here, we found that Arf6(T27N) is not an appropriate marker of the inactive GDP-bound form because it has a high tendency to ...
... the T27N and the Q67L mutants, which are thought to be blocked in GDP- and GTP-bound states, respectively. However, these mutants have been poorly characterized biochemically. Here, we found that Arf6(T27N) is not an appropriate marker of the inactive GDP-bound form because it has a high tendency to ...
Endoplasmic Reticulum Export Sites and Golgi Bodies Behave as
... ER-to-Golgi protein transport may occur in plants. It was proposed that Golgi bodies move between fixed ERES in an actinmyosin–dependent fashion (stop-and-go model; Nebenführ et al., 1999). This model suggests that Golgi bodies become competent for cargo collection once they come to a halt on an ER ...
... ER-to-Golgi protein transport may occur in plants. It was proposed that Golgi bodies move between fixed ERES in an actinmyosin–dependent fashion (stop-and-go model; Nebenführ et al., 1999). This model suggests that Golgi bodies become competent for cargo collection once they come to a halt on an ER ...
Print - Circulation
... autoinhibitory calmodulin-binding domain. Calmodulin can increase the activity of the protein by binding to this amino acid sequence, presumably interfering with the interaction of this domain with other components of the molecule and thus relieving the autoinhibition. Recently, Li et al'5 have synt ...
... autoinhibitory calmodulin-binding domain. Calmodulin can increase the activity of the protein by binding to this amino acid sequence, presumably interfering with the interaction of this domain with other components of the molecule and thus relieving the autoinhibition. Recently, Li et al'5 have synt ...
Divalent Cation-Dependent Formation of
... that the buffer in this case contains only 1 mM EDTA. Monolayer samples are transferred from the trough onto a glass coverslip, both before and after addition of divalent salt. These films are imaged on a NanoScope III atomic force microscope (Digital Instruments, Tonawanda, NY) in tapping mode. We ...
... that the buffer in this case contains only 1 mM EDTA. Monolayer samples are transferred from the trough onto a glass coverslip, both before and after addition of divalent salt. These films are imaged on a NanoScope III atomic force microscope (Digital Instruments, Tonawanda, NY) in tapping mode. We ...
The mechanism of Stx2 enrichment in outer membrane vesicles of
... recovery. About 15% of the time the disease progresses into life-threatening hemolytic uremic syndrome (HUS) [17], which children and the elderly are particularly susceptible to develop [18]. Stx production is thought to be strongly linked to STEC pathogenesis and HUS [19, 20]. Treatment of STEC inf ...
... recovery. About 15% of the time the disease progresses into life-threatening hemolytic uremic syndrome (HUS) [17], which children and the elderly are particularly susceptible to develop [18]. Stx production is thought to be strongly linked to STEC pathogenesis and HUS [19, 20]. Treatment of STEC inf ...
Eucalyptus Arabidopsis grandis thaliana
... approaches have been considered to accelerate the domestication of forest trees. The first is through the genetic modification of trees by introducing new genes into existing genotypes to confer advantageous phenotypes and the second is through marker-assisted breeding of new variants. Both of these ...
... approaches have been considered to accelerate the domestication of forest trees. The first is through the genetic modification of trees by introducing new genes into existing genotypes to confer advantageous phenotypes and the second is through marker-assisted breeding of new variants. Both of these ...
Myosin V Plays an Essential Role in the Thyroid Hormone
... the perinuclear space (5, 10). Myosin motor proteins mediate the translocation of vesicle on actin fibers. Myosins comprise a superfamily of actin-binding, Mg2⫹-ATPase, motor proteins (11), and unconventional myosins are found in virtually all cell types, where they participate in cell contraction, ...
... the perinuclear space (5, 10). Myosin motor proteins mediate the translocation of vesicle on actin fibers. Myosins comprise a superfamily of actin-binding, Mg2⫹-ATPase, motor proteins (11), and unconventional myosins are found in virtually all cell types, where they participate in cell contraction, ...
Differential assembly of polypeptides of the light
... both LH complexes consist of heterodimers of a- and bpolypeptides containing 50–60 amino acid residues (Theiler et al. 1984, 1985), which in LH1, bind two molecules of BChl (B875 BChl with Qy absorption band at 876 nm and two carotenoids (Broglie et al. 1980), and in LH2, two B850 BChls, one B800 BC ...
... both LH complexes consist of heterodimers of a- and bpolypeptides containing 50–60 amino acid residues (Theiler et al. 1984, 1985), which in LH1, bind two molecules of BChl (B875 BChl with Qy absorption band at 876 nm and two carotenoids (Broglie et al. 1980), and in LH2, two B850 BChls, one B800 BC ...
Overall energy conversion efficiency of a photosynthetic vesicle | eLife
... In addition to ATP synthesis, the chromatophore utilizes the generated proton motive force also for NADH production via NADH dehydrogenase (Klamt et al., 2008) and, thereby, for control of the quinone/quinol pool redox state. Other channels for proton gradient depletion are flagellar motility (Kojad ...
... In addition to ATP synthesis, the chromatophore utilizes the generated proton motive force also for NADH production via NADH dehydrogenase (Klamt et al., 2008) and, thereby, for control of the quinone/quinol pool redox state. Other channels for proton gradient depletion are flagellar motility (Kojad ...
SNARE (protein)
SNARE proteins (an acronym derived from ""SNAP (Soluble NSF Attachment Protein) REceptor"") are a large protein superfamily consisting of more than 60 members in yeast and mammalian cells. The primary role of SNARE proteins is to mediate vesicle fusion, that is, the fusion of vesicles with their target membrane bound compartments (such as a lysosome). The best studied SNAREs are those that mediate docking of synaptic vesicles with the presynaptic membrane in neurons. These SNAREs are the targets of the bacterial neurotoxins responsible for botulism and tetanus.