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Evolving genetic code - J
Evolving genetic code - J

... mitochondrial codes (for refs., see Osawa et al.3), Osawa4)) It is therefore misleading to think that ‘‘the genetic code is strikingly (or nearly) universal, but there exist some exceptions’’. Such a description may be found in many text books. In reality, the genetic code is obviously not universal ...
Evolving genetic code
Evolving genetic code

... mitochondrial codes (for refs., see Osawa et al.3), Osawa4)) It is therefore misleading to think that ‘‘the genetic code is strikingly (or nearly) universal, but there exist some exceptions’’. Such a description may be found in many text books. In reality, the genetic code is obviously not universal ...
Variability of Wax Ester Fermentation in Natural and Bleached
Variability of Wax Ester Fermentation in Natural and Bleached

... (Trenkamp et al. 2004). The mitochondrial fatty acid synthesis of E. gracilis -/25 strain Z occurs, as well as the elongation system, via CoA esters instead of ACP proteins (Hoffmeister et al. 2005). Addition of 100 mM of the elongase inhibitor flufenacet to anaerobic cultures enhanced the synthesis ...
Amino Acids in Maturation Medium and Presence
Amino Acids in Maturation Medium and Presence

... Division of Animal Science and Technology,s Faculty of Agriculture, Okayama University, Okayama 700, Japan Department of Animal Science and Technology,6 College of Agriculture and Life Sciences, Seoul National University, Suweon, 441-744, Korea ABSTRACT The present study was conducted to examine the ...
Metabolic downregulation during diapause in embryos of Artemia
Metabolic downregulation during diapause in embryos of Artemia

... water (water replacement theory) (Crowe et al. 1998, Webb 1965). In addition, because it is a non-reducing sugar, trehalose does not undergo browning reactions with the amine groups of proteins (Crowe and Clegg, 1973). The protective capacity of trehalose extends to other forms of water stress, such ...
Presentation 2013-201307040352
Presentation 2013-201307040352

... It is noteworthy that carnitine is an essential nutrient for newborn infants because the mechanism of its biosynthesis is not fully developed until later in postnatal development. The primary source of carnitine for a newborn is from the mother's milk (Sandor et al., 1982). The neonatal intestine ha ...
Probing peroxisomal β-oxidation and the labelling of acetyl
Probing peroxisomal β-oxidation and the labelling of acetyl

... The discrepancy between the labelling of the C1 + 2 fragment of BHB and that of the acetyl moiety of citrate probably results from associations of enzymes resulting in metabolic channelling of intermediates [21,22], especially at low flux rate. Previous studies had concluded that the labelling of li ...
FA + GLYCEROL
FA + GLYCEROL

... TOTAL RESULT OF 7 STEPS – production of 4 Carbon compound ...
regulating direct-to-consumer genetic testing
regulating direct-to-consumer genetic testing

... the results they receive or understand precisely what those results do (or do not) mean is a question that has been overlooked as regulatory policy lags behind the commercial genetic testing industry.18 Part I of this Note provides background on the rise of genetic testing as a regular part of medic ...
Molecular basis of hepatic carnitine palmitoyltransferase I deficiency
Molecular basis of hepatic carnitine palmitoyltransferase I deficiency

... zyme (CPT I) is localized in the outer-mitochondrial membrane and converts the fatty acyl-CoA ester to its carnitine ester. This carnitine ester is subsequently transported across the mitochondrial inner membrane by CAC which belongs to the mitochondrial carrier family. Once inside the mitochondrial ...
Ketone body metabolism and cardiovascular disease - AJP
Ketone body metabolism and cardiovascular disease - AJP

... Submitted 30 August 2012; accepted in final form 6 February 2013 ...
A re-evaluation of the ATP :NADPH budget
A re-evaluation of the ATP :NADPH budget

... Department of Biochemistry and Physiology, IACR-Rothamsted, Harpenden, Herts AL5 2JQ, UK Received 11 July 1998; Accepted 4 August 1998 ...
Protein O-linked β-N-acetylglucosamine
Protein O-linked β-N-acetylglucosamine

... of proteins that become secreted or membrane component glycoproteins [1]. Importantly these glycosylation reactions occur exclusively in the ER and Golgi; however, in 1984 a novel glycosylation modification was first reported in which a single β-N-acetyl-glucosamine moiety was attached via an O-linkag ...
Figure 4 - Scientific Research Publishing
Figure 4 - Scientific Research Publishing

... apparatus of muscle fibers. Structure of myofibrils creates contractile function and the function designs structure. The importance of this relationship changes in situations of different functional demands. Striated muscle tissue contains fibers with high oxidative capacity (heart muscle), higher o ...
Glycerol is a major substrate for glucose, glycogen, and
Glycerol is a major substrate for glucose, glycogen, and

... Care and Use Committee follows the guidelines mandated by the Animal Welfare Act, Public Health Service Policy on Humane Care and Use of Laboratory Animals, and the Guidelines for the Care and Use of Laboratory Animals, which do not regulate the use of embryonated avian eggs in research. Further, th ...
Isolation and Fractionation 2
Isolation and Fractionation 2

... M = Succinate Cytochrome c Reductase (Mitochondrial marker). ...
Full-Text PDF
Full-Text PDF

... mostly in neurons. As astrocytes secrete citrate into extracellular medium, the potential function of SLC13A5 in neurons is to mediate the uptake of circulating citrate and astrocyte-released citrate for subsequent metabolism. Slc13a5-knockout mice have been generated; these mice do not have any ove ...
Nicotinamide adenine dinucleotide homeostasis and
Nicotinamide adenine dinucleotide homeostasis and

... molecule that is used by different pathways involved in the regulation of energy metabolism (Sirtuins), response to oxidative stress (PARP, Sirtuins) and Ca2+ signaling (CD38), setting NAD+ as a major regulatory hub directly interfacing energy metabolism and cellular functions (Figure 1). NAD+-depen ...
General introduction - University of Amsterdam
General introduction - University of Amsterdam

... C. albicans is a polymorphic diploid ascomycete that is a commensal in healthy human hosts, but an opportunistic pathogen when the immune system is weakened. Several clades exist worldwide: North American clades I-III and European and African-specific clades, but no correlation has been found between ...
COMPUTATIONAL MODELING OF CHARGE TRANSFER IN NUCLEOBASE-AROMATIC AMINO ACID COMPLEXES Cristina BUTCHOSA ROBLES
COMPUTATIONAL MODELING OF CHARGE TRANSFER IN NUCLEOBASE-AROMATIC AMINO ACID COMPLEXES Cristina BUTCHOSA ROBLES

... que m’han animat ...
Monoclonal Antibodies Specific for Oxidative Phosphorylation
Monoclonal Antibodies Specific for Oxidative Phosphorylation

... Molecular Probes offers a range of subunit-specific antibodies for the study of mitochondrial function and dysfunction (Tables 1–3 and Figure 1), including monoclonal antibodies specific for subunits of human COX (Complex IV) and for representative subunits of human Complexes I, II, III and V. These ...
Hypoxia in skeletal muscles: from physiology to gene expression
Hypoxia in skeletal muscles: from physiology to gene expression

... hypoxia. [23]. Recently, Jacobs et al. reported an increase in the mitochondrial volume density in skeletal muscle after 28 days of exposure to high altitude [41], where the mitochondrial function is not affected through either complex I or complex II [42] . This result partially agrees with Horscro ...
Gluconeogenesis differs in developing chick embryos derived from
Gluconeogenesis differs in developing chick embryos derived from

... The normalized crude ion abundances of glucose and AA were corrected for the natural abundance of stable isotopes present in the original molecule and that contributed by the derivative using the matrix approach (Fernandez et al., 1996). Natural isotopomer distributions in unlabelled glucose and AA ...
Evidence for Several Cysteine Transport Mechanisms in the
Evidence for Several Cysteine Transport Mechanisms in the

... IMM; (ii) a single cysteine-specific transporter with a low affinity but high transport rate of cysteine; or (iii) the combined action of several saturable cysteine uptake systems with different affinities in the IMM that mimic a non-saturable cysteine uptake under the experimental conditions applie ...
New Insights into the Interaction of Carbohydrate and Fat
New Insights into the Interaction of Carbohydrate and Fat

... 1.8 mmol/L FFAs) while the availability of glucose was held constant. The philosophy was that carbohydrate was the default fuel of the muscles and when fat was available it was used and spared some carbohydrate. The goal was to explain the mechanisms responsible for carbohydrate downregulation and t ...
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Mitochondrial replacement therapy

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