Memory fields of neurons in the primate prefrontal cortex
... for complex stimuli that resemble the objects monkeys encounter in their experiences outside the neurophysiological laboratory (14, 15). Little is known about how or whether PF neurons convey their spatial attributes. The PF cortex plays an important role in a variety of functions critical for compl ...
... for complex stimuli that resemble the objects monkeys encounter in their experiences outside the neurophysiological laboratory (14, 15). Little is known about how or whether PF neurons convey their spatial attributes. The PF cortex plays an important role in a variety of functions critical for compl ...
Integrating Optogenetic and Pharmacological Approaches to Study
... circumventing many of the limitations of conventional methods. Although the enthusiasm for optogenetic tools is well deserved, these methods also have some inherent limitations. We propose that the specificity of optogenetic manipulations is enhanced when used in combination with pharmacological met ...
... circumventing many of the limitations of conventional methods. Although the enthusiasm for optogenetic tools is well deserved, these methods also have some inherent limitations. We propose that the specificity of optogenetic manipulations is enhanced when used in combination with pharmacological met ...
PowerPoint 演示文稿 - Shandong University
... cerebellum, where it is used to adjust muscle tension Simultaneously, motor neurons in the spinal cord supplying the contracting muscle are inhibited and antagonistic muscle are activated (activation) ...
... cerebellum, where it is used to adjust muscle tension Simultaneously, motor neurons in the spinal cord supplying the contracting muscle are inhibited and antagonistic muscle are activated (activation) ...
Advanced biomaterial strategies to transplant preformed micro
... the human brain possesses tremendous cognitive, sensory, and motor capabilities; however, despite all of these features, the brain is rather limited to repair itself in response to a large deficit such as stroke, severe traumatic brain injury (TBI), or chronic neurodegeneration. Reasons for this incl ...
... the human brain possesses tremendous cognitive, sensory, and motor capabilities; however, despite all of these features, the brain is rather limited to repair itself in response to a large deficit such as stroke, severe traumatic brain injury (TBI), or chronic neurodegeneration. Reasons for this incl ...
Cell-Type Specific Channelopathies in the Prefrontal Cortex of the
... pattern of results from published findings from hippocampus where Ih is up-regulated and A-type K! channel function is down-regulated. Additionally, we find that somatic Kv1-mediated current is down-regulated, resulting in increased excitability of fmr1-/y PT neurons. Importantly, these h- and K! ch ...
... pattern of results from published findings from hippocampus where Ih is up-regulated and A-type K! channel function is down-regulated. Additionally, we find that somatic Kv1-mediated current is down-regulated, resulting in increased excitability of fmr1-/y PT neurons. Importantly, these h- and K! ch ...
Muscular System
... o Neurotransmitters are stored in membrane-bound vesicles of the nerve ending (axon terminal), each containing thousands of neurotransmitter molecules. o When an impulse moves along the axon and arrives at the axon terminal, these vesicles migrate to the membrane in the gap and release their neurot ...
... o Neurotransmitters are stored in membrane-bound vesicles of the nerve ending (axon terminal), each containing thousands of neurotransmitter molecules. o When an impulse moves along the axon and arrives at the axon terminal, these vesicles migrate to the membrane in the gap and release their neurot ...
Huffman PowerPoint Slides
... • The synapse is the junction between an axon terminal and an adjacent dendrite • Neurotransmitters are released from the axon terminal in response to an action potential into the synapse – The molecules diffuse across the synapse – NT molecules interact with receptors to alter the potential of the ...
... • The synapse is the junction between an axon terminal and an adjacent dendrite • Neurotransmitters are released from the axon terminal in response to an action potential into the synapse – The molecules diffuse across the synapse – NT molecules interact with receptors to alter the potential of the ...
13 Peripheral Nervous a
... respond to chemical levels in the blood Pain receptors and proprioceptors do not exhibit ...
... respond to chemical levels in the blood Pain receptors and proprioceptors do not exhibit ...
Novel cyclic AMP signalling avenues in learning and memory
... platform for integrating opposite signaling events to the same subcellular site. It has been suggested that in excitatory synapses at the PSD, AKAP79/150 targets its anchored proteins and forms a multi protein complex with AMPA and NMDA receptors ...
... platform for integrating opposite signaling events to the same subcellular site. It has been suggested that in excitatory synapses at the PSD, AKAP79/150 targets its anchored proteins and forms a multi protein complex with AMPA and NMDA receptors ...
GLIA: LISTENING AND TALKING TO THE SYNAPSE
... would not be sufficient by itself to account for the spread of the Ca2+ wave. Therefore, some form of regeneration of the source of Ins(1,4,5)P3 would be required to explain it35,37. Although the partially regenerative nature of the signal could involve the Ca2+-dependent activation of PLC, an alter ...
... would not be sufficient by itself to account for the spread of the Ca2+ wave. Therefore, some form of regeneration of the source of Ins(1,4,5)P3 would be required to explain it35,37. Although the partially regenerative nature of the signal could involve the Ca2+-dependent activation of PLC, an alter ...
serotonergic modulation of swimming speed in the pteropod mollusc
... Escape swimming involves different neural mechanisms and its examination is beyond the scope of the current study. In the previous paper, a cluster of pedal serotoninimmunoreactive neurons (Pd-SW cells) was described which produced peripheral modulation of muscle contractility in the swimming system ...
... Escape swimming involves different neural mechanisms and its examination is beyond the scope of the current study. In the previous paper, a cluster of pedal serotoninimmunoreactive neurons (Pd-SW cells) was described which produced peripheral modulation of muscle contractility in the swimming system ...
2 - New Page 1
... median preoptic nucleus (MnPN) neurons increases during sleep • Project inhibitory axons (secreting GABA) to TMN, dorsal pons, raphe nuclei, and LC, which govern arousal • Receives inhibitory input from TMN, raphe nuclei, and LC • Mutual inhibition forms flip-flop circuit that controls sleep vs. wak ...
... median preoptic nucleus (MnPN) neurons increases during sleep • Project inhibitory axons (secreting GABA) to TMN, dorsal pons, raphe nuclei, and LC, which govern arousal • Receives inhibitory input from TMN, raphe nuclei, and LC • Mutual inhibition forms flip-flop circuit that controls sleep vs. wak ...
Alterations of Mitochondria and Golgi Apparatus Are
... terminals is dramatically decrease and their structural pattern changes [45]. That modification might be attributed to enhanced nitrosative stress, generated by Aβ peptide, leading to mitochondrial fission, which is followed by mitochondrial depletion, resulting in synaptic degeneration eventually [ ...
... terminals is dramatically decrease and their structural pattern changes [45]. That modification might be attributed to enhanced nitrosative stress, generated by Aβ peptide, leading to mitochondrial fission, which is followed by mitochondrial depletion, resulting in synaptic degeneration eventually [ ...
View Article
... computer emits a click. If you listen, you can tell how busy Thor’s brain is under the electrode array. It sounds like popcorn popping. But then, suddenly, every line on the monitor turns gray and freezes. The clicks stop. A grad student checks the cables leading to the titanium plug in Thor’s skull ...
... computer emits a click. If you listen, you can tell how busy Thor’s brain is under the electrode array. It sounds like popcorn popping. But then, suddenly, every line on the monitor turns gray and freezes. The clicks stop. A grad student checks the cables leading to the titanium plug in Thor’s skull ...
Central neural control of the cardiovascular system
... changes in metabolic activity (1). Apart from physical exercise, coordinated cardiovascular and respiratory mechanisms regulate the O2 supply to all tissue during other behaviors, such as defensive behavior or sleep. In addition, such regulatory mechanisms are also required to maintain homeostasis i ...
... changes in metabolic activity (1). Apart from physical exercise, coordinated cardiovascular and respiratory mechanisms regulate the O2 supply to all tissue during other behaviors, such as defensive behavior or sleep. In addition, such regulatory mechanisms are also required to maintain homeostasis i ...
A visual motion detection circuit suggested by Drosophila
... been frustrated by the lack of detailed synaptic connection maps, or connectomes. For example, despite intensive investigations over half a century, the neuronal implementation of local motion detection in the insect visual system remains elusive. Here we develop a semi-automated pipeline using elec ...
... been frustrated by the lack of detailed synaptic connection maps, or connectomes. For example, despite intensive investigations over half a century, the neuronal implementation of local motion detection in the insect visual system remains elusive. Here we develop a semi-automated pipeline using elec ...
LWW PPT Slide Template Master
... • With threshold stimulus, neuron generates impulse (action potential) – Depolarization – Refractory period – Repolarization Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins ...
... • With threshold stimulus, neuron generates impulse (action potential) – Depolarization – Refractory period – Repolarization Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins ...
Chapter 10 Neurology
... recurring condition in which neurons in the brain spontaneously send out electrical impulses in an abnormal, uncontrolled way a neurotransmitter that stimulates the sympathetic division, “fight or flight” to elicit or draw forth numerical scale that measures the depth of a coma from 1 to 15. un ...
... recurring condition in which neurons in the brain spontaneously send out electrical impulses in an abnormal, uncontrolled way a neurotransmitter that stimulates the sympathetic division, “fight or flight” to elicit or draw forth numerical scale that measures the depth of a coma from 1 to 15. un ...
High-performance genetically targetable optical neural silencing by
... The ability to silence the activity of genetically specified neurons in a temporally precise fashion would open up the ability to investigate the causal role of specific cell classes in neural computations, behaviors, and pathologies. Here we show that members of the class of light-driven outward pr ...
... The ability to silence the activity of genetically specified neurons in a temporally precise fashion would open up the ability to investigate the causal role of specific cell classes in neural computations, behaviors, and pathologies. Here we show that members of the class of light-driven outward pr ...
Functional Connectivity during Surround Suppression in
... The response of neurons whose receptive fields were overlapping with the stimulus position, was used to assign the 200msec time epoch corresponding to each stimulus presentation into two groups. When the response of the neuron was below its maximum value while the stimulus radius was larger than the ...
... The response of neurons whose receptive fields were overlapping with the stimulus position, was used to assign the 200msec time epoch corresponding to each stimulus presentation into two groups. When the response of the neuron was below its maximum value while the stimulus radius was larger than the ...
Ch 50 - MsBabbey
... the CNS 3. Perception: the brain processes the input into understandable images 4. Amplification and Adaptation: signals are increased or decreased based on importance ...
... the CNS 3. Perception: the brain processes the input into understandable images 4. Amplification and Adaptation: signals are increased or decreased based on importance ...
A Brief Overview of Molecular Mechanisms of Depression and its
... Major depressive disorder (MDD) is a widespread, chronic, and debilitating mood disorder with a lifetime prevalence of up to 20% in the US adult population (Kessler et al., 2003). Its symptoms include loss of motivation, deleterious changes in sleep and appetite, anhedonia, feelings of despair, and ...
... Major depressive disorder (MDD) is a widespread, chronic, and debilitating mood disorder with a lifetime prevalence of up to 20% in the US adult population (Kessler et al., 2003). Its symptoms include loss of motivation, deleterious changes in sleep and appetite, anhedonia, feelings of despair, and ...
introduction to peripheral nervous system 26. 02. 2014
... axons (fibers) are collected into bundles supported by connective tissue to form a nerve. The nervous system contains both the somatic system and the autonomic system, each with portions within the CNS and PNS. The somatic system mediates information between the CNS and the skin, skeletal muscles (v ...
... axons (fibers) are collected into bundles supported by connective tissue to form a nerve. The nervous system contains both the somatic system and the autonomic system, each with portions within the CNS and PNS. The somatic system mediates information between the CNS and the skin, skeletal muscles (v ...
Molecular neuroscience
Molecular neuroscience is a branch of neuroscience that observes concepts in molecular biology applied to the nervous systems of animals. The scope of this subject primarily pertains to a reductionist view of neuroscience, considering topics such as molecular neuroanatomy, mechanisms of molecular signaling in the nervous system, the effects of genetics on neuronal development, and the molecular basis for neuroplasticity and neurodegenerative diseases. As with molecular biology, molecular neuroscience is a relatively new field that is considerably dynamic.