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Gustatory processing is dynamic and distributed Donald B
Gustatory processing is dynamic and distributed Donald B

... between regions also modulate taste responses (see also [39]). Indeed, recent evidence showed that feedback connections between GC and NST modulate NST activity via both excitatory pathways and GABAergic synapses [40•]. Figure 4c shows an example of a GC–NST interaction. It is clear that cortical ac ...
Neurophysiological bases underlying the organization of intentional
Neurophysiological bases underlying the organization of intentional

... at two distinct levels: prior intentions (e.g. to replace a burned out light bulb later on) and intention-in-action (i.e. the internal state that guides and monitors the arm lifting movement while reaching the light bulb). Several other theorists followed this dualistic approach, distinguishing betw ...
Book of Abstracts - Oxygen Club of California
Book of Abstracts - Oxygen Club of California

... H Hageman, G.J. ............................... 136 Hagen, T.M.......................................45 Hager, K............................................12 Hamilton, R.T. ....................... 81,85,93 Han, D. ........... 79,80,115,119,126,139 Hanawa, N. ............................. 119,126 Ha ...
View PDF - CiteSeerX
View PDF - CiteSeerX

... Amygdala. The amygdala is especially critical in establishing learned associations between motivationally relevant events and otherwise neutral stimuli that become predictors of the event (27). Interactions between the basolateral and central amygdala nucleus involve autonomic and endocrine associat ...
doc GIT
doc GIT

... Resistance: at normal circumstances, the meal encounters few. It used to be thought that the various sphincters which separate the organs of the GIT played a major role regulating the transport of the meal. We now know that, normally, these sphincters do NOT offer resistance. They actually open refl ...
Learning place cells, grid cells and invariances: A unifying model
Learning place cells, grid cells and invariances: A unifying model

... The cellular and network mechanisms that give rise to each of these firing patterns are subject to extensive experimental and theoretical research. Several computational models have been suggested to explain the emergence of grid cells [9–21], place cells [11, 22–27] and head direction cells [11, 28 ...
Cholinergic modulation of cognitive processing: insights drawn from computational models Kishan Gupta
Cholinergic modulation of cognitive processing: insights drawn from computational models Kishan Gupta

... development of pharmacological therapies requires an understanding of the relative contributions of each receptor subtype for cognitive function. Thus, with the goal of drawing attention to the differential contributions of these receptor subtypes in future modeling work we have included an introduc ...
The Neural Basis of Addiction: A Pathology of Motivation and Choice
The Neural Basis of Addiction: A Pathology of Motivation and Choice

... Amygdala. The amygdala is especially critical in establishing learned associations between motivationally relevant events and otherwise neutral stimuli that become predictors of the event (27). Interactions between the basolateral and central amygdala nucleus involve autonomic and endocrine associat ...
Figure 15.9
Figure 15.9

... • Stress ↑ sympathetic system ↑ fight-or-flight response. • ↑ production of ATP. • Dilation of the pupils. • ↑ heart rate and blood pressure. • Dilation of the airways. • Constriction of blood vessels that supply the kidneys and gastrointestinal tract. ...
Autonomic NS
Autonomic NS

... • Stress ↑ sympathetic system ↑ fight-or-flight response. • ↑ production of ATP. • Dilation of the pupils. • ↑ heart rate and blood pressure. • Dilation of the airways. • Constriction of blood vessels that supply the kidneys and gastrointestinal tract. ...
A compensatory subpopulation of motor neurons in a mouse model
A compensatory subpopulation of motor neurons in a mouse model

... whereas others degenerate. We sought to understand how loss and growth occur at individual neuromuscular junctions and whether such opposing events can occur in different branches of the same neuron or, alternatively, whether whole motor units are either compensating or degenerative. Evidence from d ...
Autonomic Nervous System
Autonomic Nervous System

... ANS helps maintain homeostasis through the involuntary activity of autonomic reflexes or visceral reflexes. Consist of smooth muscle contractions, cardiac muscle contractions, or secretion by glands that are mediated by autonomic reflex arcs in response to a specific stimulus.  Example: micturition ...
Single unit and extracellular firing rate recordings in vivo
Single unit and extracellular firing rate recordings in vivo

... (0.3 - 0.5 mg/ml) for 30 min at 37oC. After rinsing the tissue was placed in a small volume of recording solution with the following composition (in mM): NaCl 150, KCl 3.7, CaCl 2 2.0, MgCl2 2.0, HEPES 10, pH adjusted to 7.4 with NaOH. Cells were separated by gentle pipetting and placed in the recor ...
Locus coeruleus - Rice CAAM Department
Locus coeruleus - Rice CAAM Department

... explain why a norepinephrine reuptake inhibitor (desipramine, DMI) which enhance the extracellular NE levels at all noradrenergic synapses could ameliorates some symptoms in a mouse model of Rett Syndrome[12] . ...
The emergence of a shared action ontology: Building blocks for a
The emergence of a shared action ontology: Building blocks for a

... lower part of each panel illustrates schematically the experimenterÕs action as observed from the monkeyÕs vantage point: the experimenterÕs hand starting from a fixed position, moving toward an object and grasping it (panels A and B), or mimicking grasping (panels C and D). The behavioral paradigm c ...
Summary of Results and Discussion
Summary of Results and Discussion

... Previous studies by Josephson and Meier reported no alterations of Nogo-A expression at 24 hours after KA injection, and no alterations or strong upregulation after 7-5 days (Table 1.1; Josephson et al., 2001; Meier et al., 2003). The doses used in the three studies were similar (10 mg/kg Josephson ...
Correlation between auditory threshold and the auditory brainstem
Correlation between auditory threshold and the auditory brainstem

... significant increase both in the I–III and in the III–V intervals; although the increase in the III–V interval was slightly more significant [42, 43]. It appears that the generators of wave V following perinatal HI may be particularly vulnerable to a physiological change probably attributed to gener ...
Structural changes that occur during normal aging of primate
Structural changes that occur during normal aging of primate

... pyramidal neurons. Also, large neurons have more lipofuscin than smaller ones, but this is not a rule, so that among the larger cortical neurons, the Meynert cells of visual cortex [27] come to contain little age pigment, while the Betz cells of motor cortex can become so full of pigment that their ...
Smell Prism - Systems Neuroscience Course, MEDS 371, Univ
Smell Prism - Systems Neuroscience Course, MEDS 371, Univ

... Olfactory sensory neurons (OSN) have dendrites with cilia containing a G-protiencoupled OR and axons that communicate to the olfactory bulb. OSN can regenerate, giving them an unusual ability to recover from injury. OSN located in separate regions use 4 subfamilies of OR, individual OSN express sing ...
Chapter 06 Abstract Neuron Models
Chapter 06 Abstract Neuron Models

... model some or even all of its dynamical equations are completely different from those of the physiological description of the neuron. Furthermore, the abstract neuron will be described by fewer equations than the physiological neuron it is meant to imitate. Were this not so, there would be no point ...
EXERCISE TRAINING AND SYMPATHETIC NERVOUS SYSTEM
EXERCISE TRAINING AND SYMPATHETIC NERVOUS SYSTEM

... of the cardiovascular system occurring in otherwise normal ‘healthy’ individuals may be important in reducing the incidence of cardiovascular disease. ...
FREE Sample Here
FREE Sample Here

...  Neurons are specialized cells that conduct impulses through the nervous system.  The cell body contains the nucleus and carries out the metabolic, or life-sustaining,  functions of a neuron.  The dendrites project out from the cell bodies are the primary receivers of signals from other neurons. ...
From Membrane to Cytoskeleton: Minireview
From Membrane to Cytoskeleton: Minireview

... During development, neurons migrate and undergo extensive morphological changes necessary to establish functional connections. Extracellular cues function through surface receptors to control signaling pathways whose interplay results in the remodeling of the cytoskeleton and thereby changes in cell ...
An implantable electrode design for both chronic in vivo
An implantable electrode design for both chronic in vivo

... responsible for the positioning of the abdomen (Kennedy and Takeda, 1965a,b; Parnas and Atwood, 1966). The design of the implanted electrode presented here allowed us to monitor neuronal activity in the distal part of the N2 of the crayfish while leaving the animal with maximum freedom of movement. ...
5104-c2
5104-c2

... mPer2 gene are cancer prone. After γ radiation, these mice show a marked increase in tumor development and reduced apoptosis in thymocytes. The core circadian genes are induced by γ radiation in wild-type mice but not in mPer2 mutant mice. Temporal expression of genes involved in cell cycle regulati ...
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Molecular neuroscience



Molecular neuroscience is a branch of neuroscience that observes concepts in molecular biology applied to the nervous systems of animals. The scope of this subject primarily pertains to a reductionist view of neuroscience, considering topics such as molecular neuroanatomy, mechanisms of molecular signaling in the nervous system, the effects of genetics on neuronal development, and the molecular basis for neuroplasticity and neurodegenerative diseases. As with molecular biology, molecular neuroscience is a relatively new field that is considerably dynamic.
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