Spatially and Functionally Distinct Roles of the PI3
... 13 DIV sympathetic neurons grown in biochemistry chambers were maintained in medium lacking NGF for 2 days before treatment with medium alone (minus sign) or medium containing NGF (150 ng/ml) for either 20 min or 8 hr. Cellular lysates were prepared from individual compartments containing cell bodie ...
... 13 DIV sympathetic neurons grown in biochemistry chambers were maintained in medium lacking NGF for 2 days before treatment with medium alone (minus sign) or medium containing NGF (150 ng/ml) for either 20 min or 8 hr. Cellular lysates were prepared from individual compartments containing cell bodie ...
- University of Alberta
... 3.1.3. Magel2-null mice have an abnormal distribution of neural cell types ......................... 59 3.1.4. Immunohistochemical analysis of tyrosine hydroxylase reaching the post-synaptic dopamine target nuclei ...................................................................................... ...
... 3.1.3. Magel2-null mice have an abnormal distribution of neural cell types ......................... 59 3.1.4. Immunohistochemical analysis of tyrosine hydroxylase reaching the post-synaptic dopamine target nuclei ...................................................................................... ...
Psychopharmacology of conditioned reward
... manner; analyses of this phenomenon may provide valuable insight into the processes that underlie reward-related learning. The effects of dopaminergic agents with different mechanisms of action in this paradigm have revealed several interesting dissociations suggesting that a rewarding signal at dop ...
... manner; analyses of this phenomenon may provide valuable insight into the processes that underlie reward-related learning. The effects of dopaminergic agents with different mechanisms of action in this paradigm have revealed several interesting dissociations suggesting that a rewarding signal at dop ...
Niemann-Pick Disease Type C: A Lipid Trafficking
... The “classic” clinical profile accounts for 50 to 60 percent of cases of NP-C in large series. Many alternative presentations have been described. Four children with fetal ascites 45, 46 have been described; only one survived the first year. Two died from hepatic failure and the other from respirato ...
... The “classic” clinical profile accounts for 50 to 60 percent of cases of NP-C in large series. Many alternative presentations have been described. Four children with fetal ascites 45, 46 have been described; only one survived the first year. Two died from hepatic failure and the other from respirato ...
AANEM Glossary of Terms in Neuromuscular
... afterdischarge 1) The continuation of action potentials in a neuron, axon or muscle fiber following the termination of an applied stimulus. 2) The continuation of firing of muscle action potentials after cessation of voluntary activation, for example in myotonia. afterpotential The membrane potentia ...
... afterdischarge 1) The continuation of action potentials in a neuron, axon or muscle fiber following the termination of an applied stimulus. 2) The continuation of firing of muscle action potentials after cessation of voluntary activation, for example in myotonia. afterpotential The membrane potentia ...
... amygdala, delineated with the striatal-related markers dopamine, adenosine 3 0 :5 0 -monophosphate regulated phosphoprotein of Mr 32 kDa, and the related phosphoprotein Inhibitor-1. These basal forebrain systems project to autonomic nuclei in the hypothalamus and brainstem. We interpret these result ...
... A simple means to begin mapping these other autoantigens in the CNS is to use patient-derived sera as primary antisera upon tissue sections. This approach has been used to demonstrate brain-directed autoantibodies in sera from patients with paraneoplastic neurological diseases [13], Stiff Person Syn ...
Neocortical Very Fast Oscillations (Ripples, 80–200 Hz) During
... Downloaded from http://jn.physiology.org/ by 10.220.32.247 on June 12, 2017 ...
... Downloaded from http://jn.physiology.org/ by 10.220.32.247 on June 12, 2017 ...
Kobayashi S, Kawagoe R, Takikawa Y, Koizumi M, Sakagami M
... In primates, behavior is influenced, at least to some extent, by the currently expected reward value. For example, when the reinforcement ratio is different for each choice position, choice behavior is biased to a position where reward is expected with a higher probability (Herrnstein 1961). The bas ...
... In primates, behavior is influenced, at least to some extent, by the currently expected reward value. For example, when the reinforcement ratio is different for each choice position, choice behavior is biased to a position where reward is expected with a higher probability (Herrnstein 1961). The bas ...
Can You Smell That? Anatomy and Physiology of Smell
... Produced by Bowman’s glands and adjacent respiratory mucosa (goblet cells) Partitioning of odorant’s molecules between air phase and mucus phase important in reaching olfactory epithelium Must be soluble in mucus but not too strongly captured to interact with the receptors Adrenergic, cholinergic, a ...
... Produced by Bowman’s glands and adjacent respiratory mucosa (goblet cells) Partitioning of odorant’s molecules between air phase and mucus phase important in reaching olfactory epithelium Must be soluble in mucus but not too strongly captured to interact with the receptors Adrenergic, cholinergic, a ...
FLRT proteins act as guidance cues for migrating cortical interneurons
... WARNING. Access to the contents of this doctoral thesis and its use must respect the rights of the author. It can be used for reference or private study, as well as research and learning activities or materials in the terms established by the 32nd article of the Spanish Consolidated Copyright Act (R ...
... WARNING. Access to the contents of this doctoral thesis and its use must respect the rights of the author. It can be used for reference or private study, as well as research and learning activities or materials in the terms established by the 32nd article of the Spanish Consolidated Copyright Act (R ...
PDF
... Strikingly, although the physical interaction of NAB-1 with SAD-1 is necessary for polarity, it is dispensable for synapse morphology. We propose that Neurabin functions as a scaffold to facilitate SAD-1-mediated phosphorylation for substrates specific for restricting axonal fate during neuronal pol ...
... Strikingly, although the physical interaction of NAB-1 with SAD-1 is necessary for polarity, it is dispensable for synapse morphology. We propose that Neurabin functions as a scaffold to facilitate SAD-1-mediated phosphorylation for substrates specific for restricting axonal fate during neuronal pol ...
Biophysics of Extracellular Action Potentials
... include low-amplitude spikes then bias is moderate. If only high amplitude units (> 200 µV) are picked up, then recording will be significantly biased towards the deep layers. The majority of spikes in cortex had a negative peak with a mean of -0.11 mV, but a minority of units (<10%) had a large pos ...
... include low-amplitude spikes then bias is moderate. If only high amplitude units (> 200 µV) are picked up, then recording will be significantly biased towards the deep layers. The majority of spikes in cortex had a negative peak with a mean of -0.11 mV, but a minority of units (<10%) had a large pos ...
Müller Cells in the Healthy Retina
... glial cell processes/contact types (Fig. 1.3) (Reichenbach, 1989b). Originating from soma which generally is located in the inner nuclear layer (where the somata of all Müller cells may even constitute a sublayer) two stem processes extend into opposite directions. The outer stem process reaches to ...
... glial cell processes/contact types (Fig. 1.3) (Reichenbach, 1989b). Originating from soma which generally is located in the inner nuclear layer (where the somata of all Müller cells may even constitute a sublayer) two stem processes extend into opposite directions. The outer stem process reaches to ...
![Metabolism of [14C]glutamate and [14C]glutamine by](http://s1.studyres.com/store/data/002383503_1-555972945f32c24447774c3be1b0f14a-300x300.png)
Metabolism of [14C]glutamate and [14C]glutamine by
... percent of the radioactivity was associated with the methanol-insoluble pellet fraction from fungal extracts, indicating slow incorporation of '"C into proteins (data not shown). The chemical form into which the remaining activity in the methanol-soluble fraction was incorporated was not investigate ...
... percent of the radioactivity was associated with the methanol-insoluble pellet fraction from fungal extracts, indicating slow incorporation of '"C into proteins (data not shown). The chemical form into which the remaining activity in the methanol-soluble fraction was incorporated was not investigate ...
Neural Networks
... Want to learn not only by reading, but also by coding? Use SNIPE! SNIPE 1 is a well-documented JAVA library that implements a framework for neural networks in a speedy, feature-rich and usable way. It is available at no cost for non-commercial purposes. It was originally designed for high performanc ...
... Want to learn not only by reading, but also by coding? Use SNIPE! SNIPE 1 is a well-documented JAVA library that implements a framework for neural networks in a speedy, feature-rich and usable way. It is available at no cost for non-commercial purposes. It was originally designed for high performanc ...
Sorting and convergence of primary olfactory axons are
... G,I–J,L–P) and paraffin (H,K) sections of P0.5 animals sections were stained with antisera raised against OMP (A,D), p75 (B,E), neuropeptide Y (C,F), Pbx-1 (G,J), Id2 (I,L), GABA (M,O), and RC2 (N,P). Sections shown in H and K were reacted with digoxigenin-labelled riboprobes corresponding to the re ...
... G,I–J,L–P) and paraffin (H,K) sections of P0.5 animals sections were stained with antisera raised against OMP (A,D), p75 (B,E), neuropeptide Y (C,F), Pbx-1 (G,J), Id2 (I,L), GABA (M,O), and RC2 (N,P). Sections shown in H and K were reacted with digoxigenin-labelled riboprobes corresponding to the re ...
Disease Modeling Using Embryonic Stem Cells
... Generation of Neurons from Wild-Type and Mecp22/y ESCs To study the role of MeCP2 during the earliest stages of neuronal maturation, we used E14 TG2a wild-type (Mecp2þ/y) and Mecp2/y ESCs [4]. Since the success of our neuronal differentiation procedure relies on the uniformity and pluripotency of t ...
... Generation of Neurons from Wild-Type and Mecp22/y ESCs To study the role of MeCP2 during the earliest stages of neuronal maturation, we used E14 TG2a wild-type (Mecp2þ/y) and Mecp2/y ESCs [4]. Since the success of our neuronal differentiation procedure relies on the uniformity and pluripotency of t ...
The Olfactory–Limbic System and Multiple Chemical
... immediately perceive the aromas of the foods being cooked, but soon afterwards you become unaware of them. Two classic examples of olfactory adaptation, which pertain to MCS, occur with the use of perfumes/colognes and from cigarette smokers. A woman may put on perfume early in the morning before he ...
... immediately perceive the aromas of the foods being cooked, but soon afterwards you become unaware of them. Two classic examples of olfactory adaptation, which pertain to MCS, occur with the use of perfumes/colognes and from cigarette smokers. A woman may put on perfume early in the morning before he ...
INFUSION OF NERVE GROWTH FACTOR (NGF) INTO KITTEN
... In addition, anti-NGF antibodies prevent normal anatomical and physiological development of the visual system when they are administered to rats by implantation of antibody-secreting hybridoma cells in the lateral ventricle (Berardi et al., 1994). These antibodies also prolong the critical period fo ...
... In addition, anti-NGF antibodies prevent normal anatomical and physiological development of the visual system when they are administered to rats by implantation of antibody-secreting hybridoma cells in the lateral ventricle (Berardi et al., 1994). These antibodies also prolong the critical period fo ...
Molecular neuroscience
Molecular neuroscience is a branch of neuroscience that observes concepts in molecular biology applied to the nervous systems of animals. The scope of this subject primarily pertains to a reductionist view of neuroscience, considering topics such as molecular neuroanatomy, mechanisms of molecular signaling in the nervous system, the effects of genetics on neuronal development, and the molecular basis for neuroplasticity and neurodegenerative diseases. As with molecular biology, molecular neuroscience is a relatively new field that is considerably dynamic.