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14.1 Nervous Control notes - Mr Cartlidge`s Saigon Science Blog
14.1 Nervous Control notes - Mr Cartlidge`s Saigon Science Blog

...  Relay neurons are found in the spinal cord, connecting sensory neurons to motor neurons;  Neurons do not connect directly with each other: there is a gap called a synapse.  The sequence of events is Stimulus (sharp pin in finger) Receptor (pain receptors in skin) Coordinator (spinal cord) Effect ...
Power Point Used in Lab
Power Point Used in Lab

... When a neuron is stimulated, not every stimulus will cause an action potential. The stimulus must be sufficient to cause the neuron to reach threshold. Only then will an action potential be produced. ...
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A leading centre for innovation, expertise, and discovery
A leading centre for innovation, expertise, and discovery

... the paths that guide axons, and has successfully isolated three of these, enabling their in-depth study. In February 2009, Dr. Culotti published a landmark study in Nature Neuroscience that revealed how opposing chemical signals help define the appropriate positioning of neurons and their axons, wit ...
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... _____________________ 3. The difference in electrical charge across a membrane _____________________ 4. Another name for a receiving neuron _____________________ 5. Another name for a transmitting neuron _____________________ 6. Is generated when a dendrite or cell body is stimulated _______________ ...
48 0007-4888/05/14010048 © 2005 Springer Science+Business
48 0007-4888/05/14010048 © 2005 Springer Science+Business

... at different stages of epileptogenesis in many epileptogenic structures under the effects of cytokines and growth factors [2,12]. The possibility of migration of neuronal precursors from the supraventricular zone and rostral migration flow into ectopic zones in the dentate fascia, olfactory tubers, ...
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Karen Iler Kirk - Purdue University
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Biology 2401 Anatomy and Physiology I notes

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... spinal cord; the PNS contains [a] sensory or afferent neurons which transmit nerve impulses from sensory receptors to the CNS, and [b] motor or efferent neurons which transmit nerve impulses from the CNS to muscles and glands. The PNS is divided into three major subdivisions: a. voluntary somatic ne ...
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BIOL241NSintro12aJUL2012
BIOL241NSintro12aJUL2012

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The Nervous System - chemistrywithmrsmorton
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BIOL241NSintro12aJUL2012
BIOL241NSintro12aJUL2012

... •  Synaptic cleft The small gap that separates the presynaptic membrane and the postsynaptic membrane •  Area of terminal containing synaptic vesicles filled with neurotransmitters ...
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Optogenetics



Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.
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