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Sensation and Perception
Sensation and Perception

... Brain responds more negatively to a taste when you are warned it will be bad Price of food influences our perception of how good it will taste People prefer familiar foods to unfamiliar ones Tastes (and taste aversions) may be acquired or ...
Topic Option A Neurobio
Topic Option A Neurobio

... humans than other animals. 14. Application: Use of animal experiments, 6. The human cerebral cortex has become enlarged autopsy, lesions and fMRI to identify the role of principally by an increase in total area with different brain parts. extensive folding to accommodate it within the 15. Skill: Ide ...
Neurotoxicity
Neurotoxicity

... General protein synthesis impairment may have an effect not only on the neurotransmitters production, but also the production of important enzymes which break down neurotransmitters when they are no longer needed. ...
Document
Document

... 1. Working in pairs, one student holds a metre rule vertically at the zero end, between the thumb and forefinger of another student, so that the 50 cm mark is level with the top of the forefinger. 2. Without warning, the first student drops the rule and the second student attempts to catch it betwee ...
4-Nervous system I: Structure and organization
4-Nervous system I: Structure and organization

... Asiatic elephant. Science 138:1100-1103. Harwood, P. 1963. Therapeutic dosage in small and large mammals . Science 139: 684-685. ...
Chapter 7
Chapter 7

... sounds transferred through the air must be transferred into a liquid medium; the ossicles aid in this transmission The cochlea is divided into 3 sections: the scala vestibuli, scala media, and scala tympani The receptive organ, the organ of Corti, consists of the basilar membrane, the hair cells, an ...
Document
Document

... – A chemical that crosses the synapse from the terminal bouton of one neuron to alter the electric potential of the membrane of the next neuron – How one neuron communicates with the ...
CHEMICAL SENSES: SMELL AND TASTE _____ = Olfaction
CHEMICAL SENSES: SMELL AND TASTE _____ = Olfaction

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179 - Edmund Rolls
179 - Edmund Rolls

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Neurons of the hippocampus form and function
Neurons of the hippocampus form and function

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High-Resolution Labeling and Functional Manipulation of Specific
High-Resolution Labeling and Functional Manipulation of Specific

... strategy suffers three major shortcomings. First, the spatial and temporal expression pattern of any one single gene may not be ideal to manipulate a cell type at a restricted developmental stage and brain region. Second, with only a few exceptions, the expression level of fluorescent markers introd ...
The Central Nervous System
The Central Nervous System

...  People with damage to Wernicke’s area can hear words or see them when written, but they do not understand their meaning. They can pronounce strings of words but their grammatical errors make their speech meaningless ...
Effects of experience on brain development
Effects of experience on brain development

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Chapter Four
Chapter Four

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The Child’s Growth

...  Photoreceptors – one of the visual-pigment-filled light-sensitive cells at the back of the retina transduce light energy into neural impulses  2 Types of Photoreceptors: i. Cones – respond to greater light intensities, give rise to chromatic (color) sensations. ii. Rods – respond to lower light i ...
Nervous Sytem notes HS Spring
Nervous Sytem notes HS Spring

... All neurons provide an all-or-none response: - in response to a stimulus, they either activate (fire) and provide a certain level of response, or don’t fire at all A neuron will only fire if it is stimulated with an intensity of at least threshold level Every action potential for a neuron is identic ...
No Slide Title
No Slide Title

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doc nervous system notes
doc nervous system notes

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7. The Nervous System Identify the major structures and areas of the
7. The Nervous System Identify the major structures and areas of the

... • Responsible for vision at low light levels (scotopic vision) • Do not mediate colour vision • Very sensitive but low resolution • 100 million rods • Contains protein rhodopsin which is made of opsin and retinal (molecule derived from Vit. A) 2) Cones • 3 types: blue, green, red • All ...
Action Potential
Action Potential

... At rest the inside of the cell is at -70 mV With inputs to dendrites inside becomes more positive if resting potential rises above threshold an action potential starts to travel from cell body down the axon Figure shows resting axon being approached by an AP ...
Slides from Lecture 12/01/2004 (Andy Clark)
Slides from Lecture 12/01/2004 (Andy Clark)

... produce different patterns of firing in the cranial nerves carrying signals from taste receptors • Substances producing similar activity patterns judged more similar (psychophysically) ...
Psychology (9th Edition) David Myers
Psychology (9th Edition) David Myers

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Tail Region of the Primary Somatosensory Cortex and Its Relation to
Tail Region of the Primary Somatosensory Cortex and Its Relation to

... noxious stimulations were used. However, the number of tail responsive channels showed a significant increase when the rat was awake and behaving. Key words Dissector method, Neuronal density, Pain, Primary somatosensory cortex, Tail ...
The Autonomic Nervous System
The Autonomic Nervous System

... Parasympathetic neurons: The parasympathetic preganglionic fibers arise from the cranium (from cranialnerves III, VII, IX, and X) and from the sacral region of the spinal cord and synapse in ganglia near or on theeffector organs. Thus, in contrast to the sympathetic system, the preganglionic fibers ...
doc Chapter 15 Notes
doc Chapter 15 Notes

... alcohol the receptors suddenly rebound and are super active and over fire Genetic factors most involving ion channels Most are caused by nongenetic factors or idiopathic (literally one’s own suffering) o Small brain abnormalities ...
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Optogenetics



Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.
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