
Rapid Taste Responses in the Gustatory Cortex
... returned to baseline in tens of milliseconds. Tastant-responsive neurons were broadly tuned and responded to increasing tastant concentrations by either increasing or decreasing their firing rates. In addition, some responses were only evoked at intermediate tastant concentrations. In summary, these ...
... returned to baseline in tens of milliseconds. Tastant-responsive neurons were broadly tuned and responded to increasing tastant concentrations by either increasing or decreasing their firing rates. In addition, some responses were only evoked at intermediate tastant concentrations. In summary, these ...
Inhibitory Neurotransmitters are the nervous system`s “off switches
... Aspartic Acid, also known as aspartate, is an excitatory neurotransmitter in the brainstem and spinal cord. Aspartic acid is the excitatory counterpart to glycine, an inhibitory neurotransmitter. Low levels have been linked to feelings of fatigue and low mood, whereas high levels have been linked t ...
... Aspartic Acid, also known as aspartate, is an excitatory neurotransmitter in the brainstem and spinal cord. Aspartic acid is the excitatory counterpart to glycine, an inhibitory neurotransmitter. Low levels have been linked to feelings of fatigue and low mood, whereas high levels have been linked t ...
spiking neuron models - Assets - Cambridge
... (or soma) of a postsynaptic cell is the synapse. The most common type of synapse in the vertebrate brain is a chemical synapse. At a chemical synapse, the axon terminal comes very close to the postsynaptic neuron, leaving only a tiny gap between pre- and postsynaptic cell membranes, called the synap ...
... (or soma) of a postsynaptic cell is the synapse. The most common type of synapse in the vertebrate brain is a chemical synapse. At a chemical synapse, the axon terminal comes very close to the postsynaptic neuron, leaving only a tiny gap between pre- and postsynaptic cell membranes, called the synap ...
Interactions Between Premotor and Motor Cortices in Non
... of skilled prehension and manipulation of objects is characteristic of the human motor system and its engagement in creative activities such as art, sculpture and music making as well as in technological development, tool use and manufacture. The highly-cited review by Jeannerod and his colleagues ( ...
... of skilled prehension and manipulation of objects is characteristic of the human motor system and its engagement in creative activities such as art, sculpture and music making as well as in technological development, tool use and manufacture. The highly-cited review by Jeannerod and his colleagues ( ...
CHAPTER 10: NERVOUS SYSTEM I
... Summation = many subthreshold stimuli received one after another may allow threshold potential to be reached, and trigger an AP, which in turn begins an impulse on a neuron. a. +15 mV = threshold = AP = impulse b. +5, +5, +5, = +15 mV = threshold = AP = impulse. ...
... Summation = many subthreshold stimuli received one after another may allow threshold potential to be reached, and trigger an AP, which in turn begins an impulse on a neuron. a. +15 mV = threshold = AP = impulse b. +5, +5, +5, = +15 mV = threshold = AP = impulse. ...
The effect of learning on the face selective responses of neurons in
... occur in a population of neurons when that population stores new information. In this study, we investigated whether individual neurons in this region alter the degree to which they respond to different stimuli when the set of stimuli starts as novel and is repeated until it becomes familiar. This m ...
... occur in a population of neurons when that population stores new information. In this study, we investigated whether individual neurons in this region alter the degree to which they respond to different stimuli when the set of stimuli starts as novel and is repeated until it becomes familiar. This m ...
Simulation of signal flow in 3D reconstructions of an anatomically
... 2003). To understand how complex neuronal output drives perception and behavior, one has to investigate the synaptic ‘wiring’ between neurons, identify the microcircuits that they form and understand how these microcircuits participate in neural networks. When it becomes possible to monitor propagat ...
... 2003). To understand how complex neuronal output drives perception and behavior, one has to investigate the synaptic ‘wiring’ between neurons, identify the microcircuits that they form and understand how these microcircuits participate in neural networks. When it becomes possible to monitor propagat ...
Electrical stimulation of neural tissue to evoke behavioral responses
... This review yields numerous conclusions. (1) Both unit recording and behavioral studies find that current activates neurons (i.e., cell bodies and axons) directly according to the square of the distance between the electrode and the neuron, and that the excitability of neurons can vary between 100 a ...
... This review yields numerous conclusions. (1) Both unit recording and behavioral studies find that current activates neurons (i.e., cell bodies and axons) directly according to the square of the distance between the electrode and the neuron, and that the excitability of neurons can vary between 100 a ...
ARTICLE IN PRESS
... memory for complex spatiotemporal trajectories (Fig. 1B). For example, the 8-arm radial maze task requires that rats visit 8 different arms without making an error by repeating an arm entry, and the number of arm re-entries is increased by fornix lesions [87,131]. The rat could avoid the error of re ...
... memory for complex spatiotemporal trajectories (Fig. 1B). For example, the 8-arm radial maze task requires that rats visit 8 different arms without making an error by repeating an arm entry, and the number of arm re-entries is increased by fornix lesions [87,131]. The rat could avoid the error of re ...
Peripheric nervous system. Vegetative nervous system
... Silver impregnation. The specimen demonstrates nerve ganglia connected with each other by nerve fibres. The ganglia contains stellate neurous of dark-brown or black color surrounded by small glial cells and nerve fibres. Light areas seen among the ganglia represent loose connective tissue where this ...
... Silver impregnation. The specimen demonstrates nerve ganglia connected with each other by nerve fibres. The ganglia contains stellate neurous of dark-brown or black color surrounded by small glial cells and nerve fibres. Light areas seen among the ganglia represent loose connective tissue where this ...
Affective neuroscience: the emergence of a discipline
... a wide range o f brain circuits concerned with different aspects of the emotional response, including behavioral and autonomic manifestations (for review, see [7°]). The connections to and from the amygdala that have been implicated in fear conditioning are illustrated in Figure 1. The critical impo ...
... a wide range o f brain circuits concerned with different aspects of the emotional response, including behavioral and autonomic manifestations (for review, see [7°]). The connections to and from the amygdala that have been implicated in fear conditioning are illustrated in Figure 1. The critical impo ...
Developmental - Schizophrenia Research Forum
... (female specific); overexpression of DNMTs mRNA in the frontal cortex; decreased GAD67, reelin, and mGlu2 and mGlu3 receptor protein levels in the frontal cortex; altered neuronal migration ...
... (female specific); overexpression of DNMTs mRNA in the frontal cortex; decreased GAD67, reelin, and mGlu2 and mGlu3 receptor protein levels in the frontal cortex; altered neuronal migration ...
Chapter 2
... autonomic nervous systems – Autonomic nervous system subdivided into sympathetic and parasympathetic nervous systems ...
... autonomic nervous systems – Autonomic nervous system subdivided into sympathetic and parasympathetic nervous systems ...
Real-time tomography from magnetoencephalography (MEG
... the view for the canonical cortical circuit, and consider the wide range of variability of neurons and their roles. We will then outline the widely accepted view about the generation of the EEG and MEG signal. In section 3, Results, we will use the processing of face stimuli to demonstrate how MEG a ...
... the view for the canonical cortical circuit, and consider the wide range of variability of neurons and their roles. We will then outline the widely accepted view about the generation of the EEG and MEG signal. In section 3, Results, we will use the processing of face stimuli to demonstrate how MEG a ...
An ontology-based search engine for digital
... suitable knowledge yielded ten cell type hierarchies spanning the morphology, neurotransmitter, development (birthday), molecular biomarker, electrophysiology, circuitry (e.g., ‘local’ vs. ‘projecting’), and functional dimensions. Unsurprisingly, the main morphological hierarchy provides the richest ...
... suitable knowledge yielded ten cell type hierarchies spanning the morphology, neurotransmitter, development (birthday), molecular biomarker, electrophysiology, circuitry (e.g., ‘local’ vs. ‘projecting’), and functional dimensions. Unsurprisingly, the main morphological hierarchy provides the richest ...
ch. 6 pdf - TeacherWeb
... the amount of brain tissue associated with the part. The touch and movement of the hands, for example, involve more brain area than the more limited calves. The somatosensory cortex, at the back of the frontal lobe, receives information from the touch sensors. The motor cortex sends information to c ...
... the amount of brain tissue associated with the part. The touch and movement of the hands, for example, involve more brain area than the more limited calves. The somatosensory cortex, at the back of the frontal lobe, receives information from the touch sensors. The motor cortex sends information to c ...
Neural coding of behavioral relevance in parietal cortex
... visual information to guide movements of the body [1–3]. Physiological studies in non-human primates and neuroimaging studies in human subjects [4] have confirmed that individual parietal neurons and cortical areas are activated during spatial, attentional, and visuomotor behaviors. Mountcastle and ...
... visual information to guide movements of the body [1–3]. Physiological studies in non-human primates and neuroimaging studies in human subjects [4] have confirmed that individual parietal neurons and cortical areas are activated during spatial, attentional, and visuomotor behaviors. Mountcastle and ...
A Glossary
... melatonin: A hormone that is secreted by the pineal gland in the brain in response to the daily light-dark cycle, influencing the body’s sleep-wake cycle and possibly affecting sexual development. memory: The encoding and storage of information, in a way that allows it to be retrieved later. In the ...
... melatonin: A hormone that is secreted by the pineal gland in the brain in response to the daily light-dark cycle, influencing the body’s sleep-wake cycle and possibly affecting sexual development. memory: The encoding and storage of information, in a way that allows it to be retrieved later. In the ...
Body and Behavior - Miami East Local Schools
... the amount of brain tissue associated with the part. The touch and movement of the hands, for example, involve more brain area than the more limited calves. The somatosensory cortex, at the back of the frontal lobe, receives information from the touch sensors. The motor cortex sends information to c ...
... the amount of brain tissue associated with the part. The touch and movement of the hands, for example, involve more brain area than the more limited calves. The somatosensory cortex, at the back of the frontal lobe, receives information from the touch sensors. The motor cortex sends information to c ...
NETMORPH: A Framework for the Stochastic
... come about during development (e.g., small-world connectivity; Sporns et al. 2004); examining how characteristic changes in synaptic connectivity, as observed in brain diseases such as Alzheimer’s disease and autism, may arise from alterations in neuronal morphology (Belmonte and Bourgeron 2006; Sch ...
... come about during development (e.g., small-world connectivity; Sporns et al. 2004); examining how characteristic changes in synaptic connectivity, as observed in brain diseases such as Alzheimer’s disease and autism, may arise from alterations in neuronal morphology (Belmonte and Bourgeron 2006; Sch ...
Functional and Dysfunctional Aspects of the Cerebral Cortex
... Introduction Diagnosis of oral motor disorders is a professional skill. Most orthodontists and other specialist dentists are familiar with the many types of oral motor behaviors and their dysfunctions, such as normal chewing, speech, improper bites, malocclusions of the teeth, and oral–facial imbala ...
... Introduction Diagnosis of oral motor disorders is a professional skill. Most orthodontists and other specialist dentists are familiar with the many types of oral motor behaviors and their dysfunctions, such as normal chewing, speech, improper bites, malocclusions of the teeth, and oral–facial imbala ...
Optogenetics

Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.