Conductance-Based Model of the Voltage
... Otsuka, Takeshi, Takafumi Abe, Takahisa Tsukagawa, and WenJie Song. Conductance-based model of the voltage-dependent generation of a plateau potential in subthalamic neurons. J Neurophysiol 92: 255–264, 2004; 10.1152/jn.00508.2003. Because the subthalamic nucleus (STN) acts as a driving force of the ...
... Otsuka, Takeshi, Takafumi Abe, Takahisa Tsukagawa, and WenJie Song. Conductance-based model of the voltage-dependent generation of a plateau potential in subthalamic neurons. J Neurophysiol 92: 255–264, 2004; 10.1152/jn.00508.2003. Because the subthalamic nucleus (STN) acts as a driving force of the ...
Ramayya, A. G., Zaghloul, K. A., Weidemann, C. T., Baltuch, G. H.
... activity using the WaveClus software package (Quiroga et al., 2005). We band-pass filtered each voltage recording from 400 to 5000 Hz and manually removed periods of motion artifact. We identified spike events as positive or negative deflections in the voltage trace that crossed a threshold that was ...
... activity using the WaveClus software package (Quiroga et al., 2005). We band-pass filtered each voltage recording from 400 to 5000 Hz and manually removed periods of motion artifact. We identified spike events as positive or negative deflections in the voltage trace that crossed a threshold that was ...
Nerve Growth Factor and Alzheimer`s Disease
... It has been considered that the high-affinity of TrkA is guaranteed by the interaction with p75, because TrkA and p75 are coexpressed in particular neurons. However, p75 is structurally belong to the tumor necrosis factor (TNF) receptor family, and has been shown to mediate cell death signals as si ...
... It has been considered that the high-affinity of TrkA is guaranteed by the interaction with p75, because TrkA and p75 are coexpressed in particular neurons. However, p75 is structurally belong to the tumor necrosis factor (TNF) receptor family, and has been shown to mediate cell death signals as si ...
The dynamic spatio-temporal behavior of visual responses in
... identical and these two stimulus situations cannot be distinguished by it. The interval pattern, however, differs. The stronger surround inhibition in A leads to more “holes” and, accordingly, the higher order intervals dominate here. In the situation depicted in C, a lower retinal impulse rate is m ...
... identical and these two stimulus situations cannot be distinguished by it. The interval pattern, however, differs. The stronger surround inhibition in A leads to more “holes” and, accordingly, the higher order intervals dominate here. In the situation depicted in C, a lower retinal impulse rate is m ...
Septins promote dendrite and axon development by negatively
... immunofluorescence ratio) via RNAi (S7KD#1, #2) or acute gene disruption (S7KO). (n ¼ 12. ***Po0.001 by one-way ANOVA with post hoc Tukey for KD, t-test for KO). Error bars denote s.e.m. (b) SEPT7 depletion efficiency (SEPT7/a-tubulin immunofluorescence ratio) in vivo via RNAi (S7KD#1). FACSsorted GFP- ...
... immunofluorescence ratio) via RNAi (S7KD#1, #2) or acute gene disruption (S7KO). (n ¼ 12. ***Po0.001 by one-way ANOVA with post hoc Tukey for KD, t-test for KO). Error bars denote s.e.m. (b) SEPT7 depletion efficiency (SEPT7/a-tubulin immunofluorescence ratio) in vivo via RNAi (S7KD#1). FACSsorted GFP- ...
The Nervous System - Fisiokinesiterapia
... Functional Classification of Neurons • Interneurons (association neurons) • Found in neural pathways in the central ...
... Functional Classification of Neurons • Interneurons (association neurons) • Found in neural pathways in the central ...
Temporal fate specification and neural progenitor competence
... The complex structure of our brain — and thus its ability to perform impressive cognitive and motor functions — depends on the production of a diverse pool of neurons and glia from a relatively small number of neural progenitors during development. It is well established that spatial patterning cues ...
... The complex structure of our brain — and thus its ability to perform impressive cognitive and motor functions — depends on the production of a diverse pool of neurons and glia from a relatively small number of neural progenitors during development. It is well established that spatial patterning cues ...
On the Role of the Pontine Brainstem in Vocal Pattern Generation: A
... and their suffering. All three experimental animals behaved normally to human caretakers and to other animals in the colony. Data analysis. Data analysis was performed using the software Spike2, version 5 (Cambridge Electronics Design). First, the original recording has been submitted to a spike-sor ...
... and their suffering. All three experimental animals behaved normally to human caretakers and to other animals in the colony. Data analysis. Data analysis was performed using the software Spike2, version 5 (Cambridge Electronics Design). First, the original recording has been submitted to a spike-sor ...
PDF file - University of Kentucky
... (i) Is there a patterned and consistent response to the opening and closing movements of the dactyl with passive movement? Next we will test for active force development related to stimulation frequency. (ii) Firmly attach a metal hook so that the tip of the hook goes through a small hole in the dac ...
... (i) Is there a patterned and consistent response to the opening and closing movements of the dactyl with passive movement? Next we will test for active force development related to stimulation frequency. (ii) Firmly attach a metal hook so that the tip of the hook goes through a small hole in the dac ...
Spiking Neurons - Computing Science and Mathematics
... A neuron in the cortex often makes connections to more than 104postsynaptic neurons. Many of its axonal branches end in the direct neighborhood of the neuron, but the axon can also stretch over several millimeters and connect to neurons in other areasof the brain . So far, we have stated that neuron ...
... A neuron in the cortex often makes connections to more than 104postsynaptic neurons. Many of its axonal branches end in the direct neighborhood of the neuron, but the axon can also stretch over several millimeters and connect to neurons in other areasof the brain . So far, we have stated that neuron ...
Loss of IP receptor function in neuropeptide Drosophila
... of the medial neurosecretory cells in the brain (Figure 1), regulate lipid homeostasis in the fat body cells of adult Drosophila [22,23]. The obese phenotype observed in adult itpr mutants suggested a role for IP3 mediated calcium signaling in modulating ILP release and secretion. However, significa ...
... of the medial neurosecretory cells in the brain (Figure 1), regulate lipid homeostasis in the fat body cells of adult Drosophila [22,23]. The obese phenotype observed in adult itpr mutants suggested a role for IP3 mediated calcium signaling in modulating ILP release and secretion. However, significa ...
Functional characterization of the synaptic
... Epilepsy is a neurodevelopmental disorder affecting almost 1 % of the population all over the world (Elger 2002; Fisher et al. 2005). Neurodevelopmental disorders comprise diseases that develop early in brain or as a consequence of head trauma, a tumor or an infection in the adult brain and span thr ...
... Epilepsy is a neurodevelopmental disorder affecting almost 1 % of the population all over the world (Elger 2002; Fisher et al. 2005). Neurodevelopmental disorders comprise diseases that develop early in brain or as a consequence of head trauma, a tumor or an infection in the adult brain and span thr ...
Neurons, Brain Chemistry, and Neurotransmission
... inhibitory neurotransmitters, tend to block the changes that cause an action potential to be generated in the responding cell. Table 2.1 lists some of the “classical neurotransmitters” used in the body and their major functions. In addition to the so-called classical neurotransmitters, there are man ...
... inhibitory neurotransmitters, tend to block the changes that cause an action potential to be generated in the responding cell. Table 2.1 lists some of the “classical neurotransmitters” used in the body and their major functions. In addition to the so-called classical neurotransmitters, there are man ...
Isodirectional Tuning of Adjacent Interneurons and Pyramidal Cells
... Dale, IL). The low impedance (100 –500 kV) of carbon-fiber electrodes gives them distinct advantages over those made with tungsten, including exceptionally low-noise (,5 mV pk-pk), improved ability to record multiple units, and increased sensitivity to smaller neurons (Armstrong-James and Millar 197 ...
... Dale, IL). The low impedance (100 –500 kV) of carbon-fiber electrodes gives them distinct advantages over those made with tungsten, including exceptionally low-noise (,5 mV pk-pk), improved ability to record multiple units, and increased sensitivity to smaller neurons (Armstrong-James and Millar 197 ...
Horizontal Synaptic Connections in Monkey Prefrontal Cortex: An In
... horizontal connections in the PFC are biased to innervate other pyramidal neurons. Given that the stripes revealed by a given tracer injection in the PFC appear to be reciprocally connected (Pucak et al., 1996), it is reasonable to hypothesize that other pyramidal neurons in the superficial layers a ...
... horizontal connections in the PFC are biased to innervate other pyramidal neurons. Given that the stripes revealed by a given tracer injection in the PFC appear to be reciprocally connected (Pucak et al., 1996), it is reasonable to hypothesize that other pyramidal neurons in the superficial layers a ...
Document
... to learn position invariant responses to new objects when presented against cluttered backgrounds is greatly reduced. This suggests that some form of attentional mechanism may be required during learning to highlight the current stimulus being attended to and suppress the effects of background noise ...
... to learn position invariant responses to new objects when presented against cluttered backgrounds is greatly reduced. This suggests that some form of attentional mechanism may be required during learning to highlight the current stimulus being attended to and suppress the effects of background noise ...
Propagation of Epileptiform Events across the Corpus Callosum in a
... (IHLs) and bilateral EEs, the extracellular recordings in BIC and BIC+MK801 were high pass filtered at 0.5 Hz using Matlab software (Mathworks, MA) and finite impulse response filtering (FIR filtering). In addition, 60 Hz noise and their harmonics were minimized by notch filtering with Butterworth a ...
... (IHLs) and bilateral EEs, the extracellular recordings in BIC and BIC+MK801 were high pass filtered at 0.5 Hz using Matlab software (Mathworks, MA) and finite impulse response filtering (FIR filtering). In addition, 60 Hz noise and their harmonics were minimized by notch filtering with Butterworth a ...
Coupling in Networks of Neuronal Oscillators (Spring 2015)
... anti-phase. Determining the eventual synchronous state of such a network of oscillators becomes quite involved when looking at three, four, or even hundreds of oscillators. This analysis becomes even harder as more and more complicated coupling mechanisms are considered. ...
... anti-phase. Determining the eventual synchronous state of such a network of oscillators becomes quite involved when looking at three, four, or even hundreds of oscillators. This analysis becomes even harder as more and more complicated coupling mechanisms are considered. ...
Restraining influence of A2 neurons in chronic control of arterial
... duration of the study (one week prior to and four weeks after viral vector microinjection) individually in metabolic cages (Tecniplast no. 3700 M071, Gazzada, Italy). WR were used as a normotensive comparator as each strain had its own control. In addition, based on their undefined genetic lineage t ...
... duration of the study (one week prior to and four weeks after viral vector microinjection) individually in metabolic cages (Tecniplast no. 3700 M071, Gazzada, Italy). WR were used as a normotensive comparator as each strain had its own control. In addition, based on their undefined genetic lineage t ...
Comprehensive imaging of cortical networks
... In contrast, typical electrophysiological studies sample only a handful of neurons in a single brain area [3]. Moreover, the type of neuron recorded and its position within the neural circuit are typically unknown [4] and long-term recording from the same neurons is inefficient [5]. As a result, the ...
... In contrast, typical electrophysiological studies sample only a handful of neurons in a single brain area [3]. Moreover, the type of neuron recorded and its position within the neural circuit are typically unknown [4] and long-term recording from the same neurons is inefficient [5]. As a result, the ...
amino acid uptake, content, and metabolism by neuronal and glial
... material located in the upper band of the 20% gradient other “cytosomes” (Fig. 1B). The amount of material in (fraction 1) was heterogeneous and not dominated by fraction 2 increased considerably during the 2nd postany single entity. Myelin-like membrane and large nu- natal week, accounting for less ...
... material located in the upper band of the 20% gradient other “cytosomes” (Fig. 1B). The amount of material in (fraction 1) was heterogeneous and not dominated by fraction 2 increased considerably during the 2nd postany single entity. Myelin-like membrane and large nu- natal week, accounting for less ...
Finally, the peak firing rate within any one place field of a single cell
... This hippocampal subfield was favored by most computational neuroscientists and electrophysiologists since its principal cells, the CA3 pyramidal cells, form a socalled “autoassociative memory network” with their abundant, local recurrent collaterals (Li et al., 1994). In computational models these ...
... This hippocampal subfield was favored by most computational neuroscientists and electrophysiologists since its principal cells, the CA3 pyramidal cells, form a socalled “autoassociative memory network” with their abundant, local recurrent collaterals (Li et al., 1994). In computational models these ...
Modulation of Synaptic Transmission to Second
... horizontal slices (250 m in thickness) were cut with a sapphire knife (Delaware Diamond Knives, Wilmington, DE) and mounted in a vibrating microtome (VT1000E; Leica Microsystems, Bannockburn, IL). Then, the slices were incubated for at least 1 h in normal aCSF that contained 124 mM NaCl, 3 mM KCl, ...
... horizontal slices (250 m in thickness) were cut with a sapphire knife (Delaware Diamond Knives, Wilmington, DE) and mounted in a vibrating microtome (VT1000E; Leica Microsystems, Bannockburn, IL). Then, the slices were incubated for at least 1 h in normal aCSF that contained 124 mM NaCl, 3 mM KCl, ...
Leech Heart CPG
... Due to their reciprocally inhibitory synapses the pair of HN(3) neurons can produce oscillations (Fig 4, B). This is the smallest group of cells that can produce oscillations and hence are called the elemental oscillator (Fig 4, C). The HN(4) neurons are also considered as an elemental or half-cente ...
... Due to their reciprocally inhibitory synapses the pair of HN(3) neurons can produce oscillations (Fig 4, B). This is the smallest group of cells that can produce oscillations and hence are called the elemental oscillator (Fig 4, C). The HN(4) neurons are also considered as an elemental or half-cente ...
Electrophysiology
Electrophysiology (from Greek ἥλεκτρον, ēlektron, ""amber"" [see the etymology of ""electron""]; φύσις, physis, ""nature, origin""; and -λογία, -logia) is the study of the electrical properties of biological cells and tissues. It involves measurements of voltage change or electric current on a wide variety of scales from single ion channel proteins to whole organs like the heart. In neuroscience, it includes measurements of the electrical activity of neurons, and particularly action potential activity. Recordings of large-scale electric signals from the nervous system such as electroencephalography, may also be referred to as electrophysiological recordings.