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Slides from Lecture 12/01/2004 (Andy Clark)
Slides from Lecture 12/01/2004 (Andy Clark)

... antagonist blocks inhibits subsequent responses ...
lecture CNS
lecture CNS

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Skeletal System
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... National Eye Institute, about 3% of Americans have glaucoma. Glaucoma cannot be ruled out by self-diagnosis based on if a person has great vision or has never had to have glasses or because their eyes feel “ok”. Glaucoma is painless, does not typically affect vision until late in the disease, and do ...
LESSON PLAN
LESSON PLAN

... Conclusion: ½ anterior part of the spinal cord has a ……… nature ½ posterior part of the spinal cord has a ……………. nature - in the central part there is the …………. canal where ………….. fluid can be found Structure of spinal nerve - the spinal nerve connects the spinal cord with r……….. and e……… Structure ...
Unit 3A Nervous System - Teacher Version
Unit 3A Nervous System - Teacher Version

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Autonomic Nervous System

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Introduction to Sensation and Perception
Introduction to Sensation and Perception

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cerebral cortex - krigolson teaching

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28. Nervous Systems

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Motor Cortex, Basal Ganglia, Cerebellum
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... send and receive energy. They say that even though the body has electromagnetic fields, these fields are too small to be meaningful. However, Dr. Becker came across a very important principle in bio-electricity which, to me, answers this criticism. The new principle is: Less is more. Small currents ...
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neural and chemical regulation of respiration

... However, if arterial po2 is less than 60mmhg, the breathing rate increases in a very steep and linear fashion. In this range of po2 pc are very sensitive to o2 and they respond so rapidly that the firing rate of the sensory neurons may change during a single breathing cycle INCREASE IN ARTERIAL PCO2 ...
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Clinically oriented anatomy of the brainstem

... A 45-year-old man complains to his family physician that there seems to be something wrong with his mouth. The examination reveals a weakness of the masticatory muscles, a deviation of the jaw to the left on closure, and a sensory loss on the same side of the lower jaw. MRI shows a tumor, presumably ...
Electrical membrane properties of rat subthalamic neurons in an in
Electrical membrane properties of rat subthalamic neurons in an in

... deviated downwards from the linearity at higher frequencies. Z~s can be seen from the graph, the STH neuron could fire at the maximum frequency of about 500 Hz (Fig. ?B). The I - f curve obtained from the last interspike interval was almost linear up to 200 Hz and reached its peak at over 300 Hz. Th ...
sensation - Warren County Schools
sensation - Warren County Schools

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Pyramidal (Voluntary Motor) System
Pyramidal (Voluntary Motor) System

... (corticospinal) results in spasticity, hyperreflexia, hypertonia, and positive Babinski sign Lower Motor Neuron: lesions of cell bodies of motor neurons (in cranial nerve motor nuclei or ventral horn of spinal cord) or their axons in nerves to the muscle (“final common pathway”) results in flaccidit ...
PDF
PDF

... approach to demonstrate that the latter phenomenon is a natural consequence of the former. In particular, we show that weak pairwise correlations of the inputs to a compartmental model of a layer V pyramidal cell can induce bimodality in its membrane potential. We show how this relationship can acco ...
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Rheobase



Rheobase is a measure of membrane excitability. In neuroscience, rheobase is the minimal current amplitude of infinite duration (in a practical sense, about 300 milliseconds) that results in the depolarization threshold of the cell membranes being reached, such as an action potential or the contraction of a muscle. In Greek, the root ""rhe"" translates to current or flow, and ""basi"" means bottom or foundation: thus the rheobase is the minimum current that will produce an action potential or muscle contraction.Rheobase can be best understood in the context of the strength-duration relationship (Fig. 1). The ease with which a membrane can be stimulated depends on two variables: the strength of the stimulus, and the duration for which the stimulus is applied. These variables are inversely related: as the strength of the applied current increases, the time required to stimulate the membrane decreases (and vice versa) to maintain a constant effect. Mathematically, rheobase is equivalent to half the current that needs to be applied for the duration of chronaxie, which is a strength-duration time constant that corresponds to the duration of time that elicits a response when the nerve is stimulated at twice rheobasic strength.The strength-duration curve was first discovered by G. Weiss in 1901, but it was not until 1909 that Louis Lapicque coined the term ""rheobase"". Many studies are being conducted in relation to rheobase values and the dynamic changes throughout maturation and between different nerve fibers. In the past strength-duration curves and rheobase determinations were used to assess nerve injury; today, they play a role in clinical identification of many neurological pathologies, including as Diabetic neuropathy, CIDP, Machado-Joseph Disease, and ALS.
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