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Autonomic nervous system
Autonomic nervous system

... the peripheral nervous system that acts as a control system functioning largely below the level of consciousness, and controls visceral functions.[1] The ANS affects heart rate, digestion, respiration rate, salivation, perspiration, diameter of the pupils, micturition (urination), and sexual arousal ...
Purinergic signaling in acupuncture
Purinergic signaling in acupuncture

... ATP, “purinergic signaling” (since ATP is a purine nucleotide), and formulated the purinergic signaling hypothesis (2). In 2009, Burnstock proposed that purinergic signaling could be involved in the physiological mechanisms mediating acupuncture effects. This hypothesis suggested that mechanical def ...
Midterm 1
Midterm 1

... C. The activated cell can either excite or inhibit the adjacent cells based on the chemicals released *D. The refractory period varies based on the strength of the activation that occurred % Correct: 61.74% Comments: The action potential is a very complex but fast-acting process. Within a few millis ...
Do neurons have a reserve of sodium channels for the generation of
Do neurons have a reserve of sodium channels for the generation of

... Currents were elicited from a holding potential of ±80 mV with voltage steps to ±20 mV (duration 5 ms, interpulse interval 4 s). The recordings are corrected for leakage currents. Action potentials were elicited from a membrane potential of ±84 to ±91 mV by current injections of 0.5 nA (duration 2 m ...
Simulating the Fröhlich Effect of Motion Misperception as a Result... Attentional Modulation in the Visual System
Simulating the Fröhlich Effect of Motion Misperception as a Result... Attentional Modulation in the Visual System

... stationary stimuli. Additionally, the main effects for motion direction, stimulus eccentricity and stimulus velocity could be simulated. Nevertheless, the amount of the simulated misperception did not correspond to the empirical Fröhlich effect. In our view, the established main effects are more imp ...
The Pathology of Multiple Sclerosis and Its Variants
The Pathology of Multiple Sclerosis and Its Variants

... plaques over the past decade (12,13), evidence that the anti-herpes drug acyclovir will reduce the number of attacks of MS (14), and, more recently, evidence for chlamydial infection (15) have renewed interest in infectious hypotheses. Because herpes viruses are activated by other infections and vir ...
Autonomic Nervous System
Autonomic Nervous System

... Non-essential activities are dampened (GI/urinary). Promotes adjustments during exercise – blood flow to organs is reduced, flow to muscles is increased. Its activity is illustrated by a person who is threatened • Heart rate increases, and breathing is rapid and deep. • The skin is cold and sweaty, ...
Neuroanatomical characteristics of deep and superficial needling
Neuroanatomical characteristics of deep and superficial needling

... superficial tissue layer is greater than that of the deep tissue layer. In considering the distribution and number of motor and sensory neurons associated with the deep and superficial tissue layers, it is clear that there are quantitative differences between the motor and sensory innervation of the ...
Skeletal System
Skeletal System

... Motor neurons in the CNS have axons that must reach to the musculature that they control that might be 3-4 feet away Any long axon is called a nerve fiber and travels in a group of fibers composing a nerve ...
The bed nucleus of the stria terminalis (BNST), a structure
The bed nucleus of the stria terminalis (BNST), a structure

... channels and an Ih dependent potential are differentially distributed. IPSPs and EPSPs are readily evoked in both dBNST and vBNST. The fast IPSP is predominantly GABAA-receptor mediated and is partially blocked by the AMPA/kainate-receptor antagonist CNQX. In the presence of the GABAA-receptor antag ...
Motion perception: Seeing and deciding
Motion perception: Seeing and deciding

... for study a specific subset of neurons in the lateral intraparietal region (LIP) of the parietal lobe that carries high-level signals appropriate for planning saccadic eye movements. These high-level signals arise early in the initial stages of planning a saccade and are therefore likely to be linke ...
Nerve activates contraction
Nerve activates contraction

... Starting a Nerve Impulse  A stimulus at threshold causes a permeability change  which depolarizes the neuron’s membrane ...
The Role of Selective Transport in Neuronal Protein
The Role of Selective Transport in Neuronal Protein

... protein to the correct cellular domain. The transport of vesicles containing TfR was almost exclusively directed into dendrites, and this selective transport alone is sufficient to account for the polarization of TfR on the dendritic surface. Downstream selectivity mechanisms may also exist, but the ...
Electrical stimulation of neural tissue to evoke behavioral responses
Electrical stimulation of neural tissue to evoke behavioral responses

... This review yields numerous conclusions. (1) Both unit recording and behavioral studies find that current activates neurons (i.e., cell bodies and axons) directly according to the square of the distance between the electrode and the neuron, and that the excitability of neurons can vary between 100 a ...
Properties of Primary Sensory (Lemniscal) Synapses in the
Properties of Primary Sensory (Lemniscal) Synapses in the

... medial lemniscus produced a very short-latency (⬃1 ms), fast-rising EPSP that peaked at ⬃2 ms. When the EPSP reaches firing threshold it produces an action potential at a latency of ⬃2 ms (Fig. 1B). Thus lemniscal synapses are extremely fast (Sabatini and Regehr 1999). Corticothalamic synapses forme ...
Exam 5 Study Guide-sp2016
Exam 5 Study Guide-sp2016

... Chapter 14 – Nervous Tissue Distinguish between a neuron and a nerve. Understand the structure and function of the nervous system and its parts: central nervous system, peripheral nervous system; sensory nervous system, including somatic and visceral systems; motor nervous system, including somatic ...
Modelling the Development of Mirror Neurons for Auditory
Modelling the Development of Mirror Neurons for Auditory

... and thus developing strong Hebbian connections. This results in such units not only receiving external, but also strong Hebbian activation, and thus becoming more active than ...
Mechanisms of Magnetic Stimulation of Central Nervous System
Mechanisms of Magnetic Stimulation of Central Nervous System

... mechanism of stimulation using the activating function (eqn. 4). The magnitude of the membrane potential change is determined by the size of the gradient of the induced electric field and the passive space constant in the axon fiber (l). Thus, for an axon fiber with spatially homogenous passive para ...
Chapter 8 & 5 powerpoint file
Chapter 8 & 5 powerpoint file

...  Predicts membrane potential using multiple ionsresting membrane potential= the contribution of all ions that cross the membrane X membrane permeability values. Ion contribution is proportional to membrane permeability for that ion. Potentials will be affected if ion concentrations change.  P=perm ...
Where is Pain Percieved?
Where is Pain Percieved?

... Pain is an inescapable sensation that every human being has experienced at least once in their lifetimes. The sensation of pain has two ways of being graded on its severity. The first is the objective intensity of pain, and the second is the subjective pain that the subject feels. Pain is one of the ...
12 Physiology of autonomic nervous system
12 Physiology of autonomic nervous system

... Generally the two divisions have chains of two motor neurons that innervate same visceral organs but cause essentially opposite effects If one division stimulates certain smooth muscle to contract or a gland to secrete, the other division inhibits that action Through this process of duel innervation ...
Exam 5 Study Guide
Exam 5 Study Guide

... Chapter 14 – Nervous Tissue Distinguish between a neuron and a nerve. Understand the structure and function of the nervous system and its parts: central nervous system, peripheral nervous system; sensory nervous system, including somatic and visceral systems; motor nervous system, including somatic ...
File
File

... If an action potential is generated in the dendrite of this cell, which of these actions will occur next? a. stimulation of a motor neuron b. depolarization in the axon of an interneuron c. depolarization in the axon of a sensory neuron d. release of neurotransmitter from an axon terminal ____ 11. U ...
Ch. 11 Review
Ch. 11 Review

... Muscle cells, which are often called fibers, contract when they receive a nerve message to do so. ...
repair of avulsed cervical nerve roots
repair of avulsed cervical nerve roots

... known and ...
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Rheobase



Rheobase is a measure of membrane excitability. In neuroscience, rheobase is the minimal current amplitude of infinite duration (in a practical sense, about 300 milliseconds) that results in the depolarization threshold of the cell membranes being reached, such as an action potential or the contraction of a muscle. In Greek, the root ""rhe"" translates to current or flow, and ""basi"" means bottom or foundation: thus the rheobase is the minimum current that will produce an action potential or muscle contraction.Rheobase can be best understood in the context of the strength-duration relationship (Fig. 1). The ease with which a membrane can be stimulated depends on two variables: the strength of the stimulus, and the duration for which the stimulus is applied. These variables are inversely related: as the strength of the applied current increases, the time required to stimulate the membrane decreases (and vice versa) to maintain a constant effect. Mathematically, rheobase is equivalent to half the current that needs to be applied for the duration of chronaxie, which is a strength-duration time constant that corresponds to the duration of time that elicits a response when the nerve is stimulated at twice rheobasic strength.The strength-duration curve was first discovered by G. Weiss in 1901, but it was not until 1909 that Louis Lapicque coined the term ""rheobase"". Many studies are being conducted in relation to rheobase values and the dynamic changes throughout maturation and between different nerve fibers. In the past strength-duration curves and rheobase determinations were used to assess nerve injury; today, they play a role in clinical identification of many neurological pathologies, including as Diabetic neuropathy, CIDP, Machado-Joseph Disease, and ALS.
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