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Structure of the Inner Ear
Structure of the Inner Ear

... Auditory hair cells are located within the organ of Corti on the basilar membrane. They derive their name from the tufts (bundles) of stereocilia that protrude from the apical surface of the cell. Pre- and postsynaptic structures located at basal pole. ...
Action potential - Solon City Schools
Action potential - Solon City Schools

... Transmits neural messages to other neurons, muscles or glands When stimulated – depolarizes ...
MR Imaging of Perineural Spread of Malignancy - SCBT-MR
MR Imaging of Perineural Spread of Malignancy - SCBT-MR

... primary nerve findings, MR is an excellent modality for characterizing muscle denervation and atrophy which are more common in the setting of malignant invasion of the peripheral nerves. Thickening and enhancement of the ipsilateral perirectal fascia is an additional finding noticed in this small co ...
Chemicals in and Around the Cell.
Chemicals in and Around the Cell.

... After completion of this chapter, the student should be able to: 1. Name and describe the parts of a neuron and explain their functions. 2. Describe the supporting cells of the central and peripheral nervous systems and describe and explain the importance of the blood–brain barrier. 3. Briefly descr ...
Nervous communication
Nervous communication

... Nervous signalling is not just fast, but also flexible ● neurones make multiple connections ● this allows us to have many possible responses A sensory neurone passes impulses from receptors to the Central Nervous System ...
DESCENDING TRACTS - University of Kansas
DESCENDING TRACTS - University of Kansas

...  Not complete paralysis  Note: complete paralysis results if both pyramidal and extrapyramidal systems are involved (as is often the case). ...
Sample
Sample

... After completion of this chapter, the student should be able to: 1. Name and describe the parts of a neuron and explain their functions. 2. Describe the supporting cells of the central and peripheral nervous systems and describe and explain the importance of the blood–brain barrier. 3. Briefly descr ...
Spinal nerves, cervical, lumbar and sacral plexus
Spinal nerves, cervical, lumbar and sacral plexus

... • Higher centers of brain incorporate lower, reflexive motor patterns • Automatic reflexes: – can be activated by brain as needed – use few nerve impulses to control complex motor functions – walking, running, jumping ...
Lecture 26 revised 03/10 Upper Motor Control Last lecture we
Lecture 26 revised 03/10 Upper Motor Control Last lecture we

... Recall- medial alpha motor neurons innervate axial and proximal limb muscles; lateral motor neurons innervate distal limb muscles. in turn, these alpha motor neurons are innervated by interneurons that are located either medially or laterally; respectively interestingly, medial and lateral interneur ...
Calcium-activated chloride channels: a new target to
Calcium-activated chloride channels: a new target to

... neurons, which might be assisted by the outwardly rectifying characteristic of the ANO2 channels. This phenotype was also observed in the knockdown of ANO2 in CA1 hippocampal neurons, providing further evidence that Ca2+-activated Cl− conductance via ANO2 channels hyperpolarizes the membrane potenti ...
Put your name here -> BIOL 415 Nerve cell
Put your name here -> BIOL 415 Nerve cell

... receptors? OR (2) have their cell bodies where? muscle spindles, dorsal root ganglion 30. VR-1 receptors ANSWER EITHER (1) can be stimulated intracellularly by what chemical? OR (2) are stimulated extracellularly by what natural stimulus? capsaicin, heat 31. The gracile nucleus is ANSWER EITHER (1) ...
A18 - Viktor`s Notes for the Neurosurgery Resident
A18 - Viktor`s Notes for the Neurosurgery Resident

... larger ones.  motor cortex does not need to specify which motoneurons to activate, it just sends signal (so number of cortex neurons can be greatly reduced!): – for minimal signal, only small motor units (with type I red muscle fibers) are activated and small force is generated; – if more force is ...
Temporal Aspects of Visual Extinction
Temporal Aspects of Visual Extinction

... root fibers • Ganglion: cell bodies of these nerves come together to create the dorsal root ganglion • Dorsal Horn or Column: information enters the spinal column at the dorsal horn ...
Acute Motor Neuropathy
Acute Motor Neuropathy

... Guilllain Barre Syndrome (GBS) GBS is a leading cause of neuromuscular paralysis world-wide (UK annual incidence of 1.0-2.0 per 100,000, with age, and M>F) In 1859 Landry described 10pts with an ascending paralysis caused by peripheral nerve dysfunction 1916 Guillain, Barre and Strohl described an ...
LEVELS OF ORGANIZATION
LEVELS OF ORGANIZATION

... There are four basic tissue types: epithelial, connective, muscle, and nervous. Their characteristics are described in detail on pgs. 76-84. It is not necessary to read these pages intensively; rather, skim to get an overview. 31. List two basic functions for each of the tissue types listed. Epithel ...
Chapter 49 Worksheet: Nervous Systems The Evolution and
Chapter 49 Worksheet: Nervous Systems The Evolution and

... 11. Describe our current understanding of the human consciousness. Recent years have seen increased study of consciousness using brain-imaging techniques such as fMRI and PET scans, making it possible to compare activity in the human brain during different states of consciousness. Support is growin ...
What Causes Eye Pain? | SpringerLink
What Causes Eye Pain? | SpringerLink

... acting directly on them or through activation of intracellular signaling cascades that phosphorylate and open TRPV1 and TRPA1 channels, causing membrane depolarization [63]. When this depolarization reaches the firing threshold, a discharge of propagated nerve impulses is generated; if the membrane ...
Nerve Tissue
Nerve Tissue

... Nerve tissue 1. Nerve tissue – characteristics, histogenesis and classification 2. Neurons – classes and structure:  cell body (perikaryon)  neuronal processes 3. Nerve fibers – types 4. Synapses 5. Neurotransmitters and receptors 6. Neuroglial cells 7. Nerve endings:  sensory (afferent) receptor ...
Nervous System
Nervous System

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Document
Document

... I am interested in the molecular mechanisms of axon guidance and synaptic target recognition – the proper wiring of all nervous systems depends on these mechanisms. A mammal’s brain is very complex, so we studied this problem using identified neurons in the cockroach, Periplaneta americana. The cerc ...
REFLEX ARCS - Anatomy.tv
REFLEX ARCS - Anatomy.tv

... A tendon reflex is initiated by a substantial amount of tension in a muscle tendon, and results in the reflex relaxation of the skeletal muscle attached to that tendon. It is less sensitive than the stretch reflex, but produces an opposite effect. 1. Golgi tendon organ The reflex begins when sensory ...
…and now, for something completely different.
…and now, for something completely different.

... When gated ion channels are open, ions diffuse quickly across the plasma membrane in the direction of their electro-chemical gradient, creating electrical currents and voltage changes across the membrane according to Ohms’s law: V+IxR ...
membrane potential
membrane potential

... voltage for a particular ion at equilibrium and can be calculated using the Nernst equation  The equilibrium potential for K is −90 mV  The resting potential of an actual neuron is about −60 to −80 mV because a small amount of Na diffuses into the cell  In a resting neuron, the currents of K a ...
Correction is highlighted
Correction is highlighted

... muscles All of the following statements comparing fast and slow-twitch muscle fibers are true EXCEPT one. Which one is the EXCEPTION? ...
File
File

... that occurs when foods with glutamate (like MSG) are eaten. Different parts of the tongue can detect all types of tastes. Morever, the simple tongue "taste map" that is found in many textbooks has been criticized for several reasons. The actual organ of taste is called the "taste bud". Each taste bu ...
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Rheobase



Rheobase is a measure of membrane excitability. In neuroscience, rheobase is the minimal current amplitude of infinite duration (in a practical sense, about 300 milliseconds) that results in the depolarization threshold of the cell membranes being reached, such as an action potential or the contraction of a muscle. In Greek, the root ""rhe"" translates to current or flow, and ""basi"" means bottom or foundation: thus the rheobase is the minimum current that will produce an action potential or muscle contraction.Rheobase can be best understood in the context of the strength-duration relationship (Fig. 1). The ease with which a membrane can be stimulated depends on two variables: the strength of the stimulus, and the duration for which the stimulus is applied. These variables are inversely related: as the strength of the applied current increases, the time required to stimulate the membrane decreases (and vice versa) to maintain a constant effect. Mathematically, rheobase is equivalent to half the current that needs to be applied for the duration of chronaxie, which is a strength-duration time constant that corresponds to the duration of time that elicits a response when the nerve is stimulated at twice rheobasic strength.The strength-duration curve was first discovered by G. Weiss in 1901, but it was not until 1909 that Louis Lapicque coined the term ""rheobase"". Many studies are being conducted in relation to rheobase values and the dynamic changes throughout maturation and between different nerve fibers. In the past strength-duration curves and rheobase determinations were used to assess nerve injury; today, they play a role in clinical identification of many neurological pathologies, including as Diabetic neuropathy, CIDP, Machado-Joseph Disease, and ALS.
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