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Author`s personal copy - Vanderbilt University
Author`s personal copy - Vanderbilt University

... Glaucoma is a common optic neuropathy with a complex etiology often linked to sensitivity to intraocular pressure. Though the precise mechanisms that mediate or transduce this sensitivity are not clear, the axon of the retinal ganglion cell appears to be vulnerable to disease-relevant stressors earl ...
THALAMUS
THALAMUS

... in the dorsal thalamus is to categorize them according to functional types: VA and VL are motor “relay” nuclei; VP (VPL & VPM), MGB, LGB and MD are sensory “relay” nuclei (don’t forget the taste relay in the medial part of VPM); LP, Pulvinar and MD are connected with association areas of cortex; the ...
Neural Activity in Macaque Parietal Cortex Reflects
Neural Activity in Macaque Parietal Cortex Reflects

... of the patch was 5° from the point of fixation, 2 The RT is the time from motion onset until saccade initiation. On all trials, the random dots were superimposed on a dim dynamic radians counterclockwise along the circle pixel noise texture background. On two-thirds of trials, the texture included a ...
Basic Mechanisms Underlying Seizures and Epilepsy
Basic Mechanisms Underlying Seizures and Epilepsy

...  Kindling model: repeated subconvulsive stimuli resulting in electrical afterdischarges • Eventually lead to stimulation-induced clinical seizures • In some cases, lead to spontaneous seizures (epilepsy) • Applicability to human epilepsy uncertain ...
Coupling in Networks of Neuronal Oscillators (Spring 2015)
Coupling in Networks of Neuronal Oscillators (Spring 2015)

... The goal of this paper is to determine the timing of a Morris-Lecar model neuron’s oscillations relative to the timing of periodic input. We create a phase model for a single Morris-Lecar model neuron that describes how a coupled neuron moves about its natural cycle in phase space as opposed to expl ...
The time of course of BDNF levels in brain and plasma after cerebral
The time of course of BDNF levels in brain and plasma after cerebral

... The brain derived neurotrophic factor (BDNF), a member of neurotrophin family protein, exerts strong survival and differentiation function during the development of the nervous system (Cohen-Cory et al. 2010). However, BDNF is still present in mature brain where it is stored and released from neuron ...
Distinct Roles for Somatically and Dendritically Synthesized Brain
Distinct Roles for Somatically and Dendritically Synthesized Brain

... antibody to GFP at DIV14, DIV21, DIV28, DIV35, and DIV42, as described above. All dendritic spines on one entire main dendrite per neuron (⬎180 ␮m in length) were traced directly under a Nikon Eclipse E800 microscope with an oil-immersion lens (Nikon; Plan APO 60⫻/NA 1.40) using Neurolucida software ...
Table of Contents
Table of Contents

... – Right hemisphere – nonverbal processing: spatial, musical, visual recognition, intuition, creativity ...
Developmental Support - Mother Baby University
Developmental Support - Mother Baby University

... germinal matrix to their eventual location within the CNS where they differentiate & take on their unique functions • Neurons formed early in life lie deeper in cortex & neurons formed later lie in more superficial layers • Cortex generally has complete component of neurons by 33 weeks gestation ...
Orexins and fear: implications for the treatment of - e
Orexins and fear: implications for the treatment of - e

... modulation of motivation and emotion (Figure 1). Specifically, orexin neuronal projections are particularly abundant in brain structures such as the mPFC, the bed nucleus of the stria terminalis, lateral septum, AMY, locus coeruleus, paraventricular hypothalamic and thalamic nuclei [26]. Reciprocall ...
avian brain nomenclature forum
avian brain nomenclature forum

... the lobus parolfactorius, the paleostriatum augmentatum, the paleostriatum primitivum, the majority of the septum and several basal forebrain groups that include the large cholinergic cells and the stria terminalis nuclear complex (part of it erroneously named nucleus accumbens in the past; see bel ...
Serotonin in Affective Control
Serotonin in Affective Control

... inhomogeneous; and different receptors can also have different temporal characteristics. Finally, the effects of the neuromodulators can be exerted very speedily, via quick-acting receptors, but can also be very prolonged, particularly through influences over long-term synaptic plasticity. This dive ...
Sensory Nerves in Adult Rats Regenerate and Restore Sensory
Sensory Nerves in Adult Rats Regenerate and Restore Sensory

... studied was completely sectioned. Using a dissecting microscope, the ensheathing connective tissue was slit open with fine forceps, exposing the nerve trunk, which was cut with scissors; the site of nerve section was marked by a loose loop of thread or a touch of India ink. In one group ofanimals, a ...
Research in Mammalian Mastication1
Research in Mammalian Mastication1

... sents the repository of distinct oral movement patterns (gnawing, unilateral chewing on right, unilateral chewing on left, suckling, etc.). It can be considered a hypothetical neural network that sets up a mechanical template for various oral movement patterns. The level B interneurons act as the pa ...
Search Department of Pediatrics, Harvard Medical School The
Search Department of Pediatrics, Harvard Medical School The

... demonstrated in situ (5 ). This reciprocating relationship might enable an even smaller subgroup of presynaptic terminals within the astrocyte's domain to precipitate a calcium wave, in turn affecting neurotransmission within the entire domain of synapses. After the pervasive and synchronous neurotr ...
No Slide Title
No Slide Title

... • descending tracts - carry motor signals down the brainstem and spinal cord • involves two neurons – upper motor neuron originate in cerebral cortex or brainstem and terminates on a lower motor neuron – lower motor neuron in brainstem or spinal cord • axon of lower motor neuron leads the rest of th ...
Central Nervous System
Central Nervous System

... Copyright (c) 2008, 2005 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved. Copyright © 2005, Elsevier, Inc. All rights reserved. ...
From Sequence to Spike to Spark: Evo-devo
From Sequence to Spike to Spark: Evo-devo

... communicate a rich variety of context-dependent social signals (Carlson, 2002a). We have a thorough understanding of the neural basis of signal production and variation, so that recording electric signals in freely behaving fish provides a direct window into their electromotor system (Bass, 1986a; C ...
chapt13_lecture
chapt13_lecture

... • descending tracts - carry motor signals down the brainstem and spinal cord • involves two neurons – upper motor neuron originate in cerebral cortex or brainstem and terminates on a lower motor neuron – lower motor neuron in brainstem or spinal cord • axon of lower motor neuron leads the rest of th ...
The role of sodium channels in neuropathic pain
The role of sodium channels in neuropathic pain

... decreases in Nav1.1, Nav1.2, and Nav1.7 expression in axotomised DRG neurons [38,40,52], it would appear that Nav1.3 becomes the predominant TTX-S channel in injured DRG neurons. Significantly, the ectopic discharges and mechanical allodynia associated with the SNL model of neuropathic pain are both ...
Dopaminergic control of the globus pallidus and its impact
Dopaminergic control of the globus pallidus and its impact

... control exerted by dopamine on basal ganglia (BG), especially the "external part of globus pallidus or GPe". GPe being a nucleus, which plays a key role in the control of movement by exerting an inhibitory influence on the output structures of the BG circuitry. The action of dopamine is mediated by ...
Comparative Study of c-Fos Expression in Rat Dorsal Vagal
Comparative Study of c-Fos Expression in Rat Dorsal Vagal

... DMV, NTS and AP have complicated neuronal contact and close correlation in function, so that they constitute the dorsal vagal complex (DVC) (4). Thus, DVC and NA are the primary nerve centres that regulate gastric functions. Nevertheless, whether the neurons of DMV, NTS, AP and NA are excited, and c ...
Sample
Sample

... 21. When a cell is “at rest,” it is in a state called the __________. a) stopping point b) obcipitation junction Incorrect. This is a fictitious word. c) resting potential Correct. A cell at rest is in a state called the resting potential. d) action potential ANS: c, p. 40, C, LO=2.2, (1) 22. The me ...
Oscillatory phase coupling coordinates
Oscillatory phase coupling coordinates

... ignificant progress has been made in understanding the dynamics and response properties of single nerve cells (1, 2) and how they interconnect to form cortical microcircuits (3, 4). More than 60 y ago, however, Donald Hebb hypothesized that the fundamental unit of brain operation is not the single ne ...
morphological changes in chick embryo neural tissue associated
morphological changes in chick embryo neural tissue associated

... Histological evaluation of the neural tissue of chick embryos exposed to 0.137M and 0.685M hydrocortisone showed reduced neuron density and morphological changes associated with cell death. Glutaraldehyde with added magnesium chloride (MgCl2) as stabilizing chemical and potassium permangenate were ...
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Feature detection (nervous system)

Feature detection is a process by which the nervous system sorts or filters complex natural stimuli in order to extract behaviorally relevant cues that have a high probability of being associated with important objects or organisms in their environment, as opposed to irrelevant background or noise. Feature detectors are individual neurons – or groups of neurons – in the brain which code for perceptually significant stimuli. Early in the sensory pathway feature detectors tend to have simple properties; later they become more and more complex as the features to which they respond become more and more specific. For example, simple cells in the visual cortex of the domestic cat (Felis catus), respond to edges – a feature which is more likely to occur in objects and organisms in the environment. By contrast, the background of a natural visual environment tends to be noisy – emphasizing high spatial frequencies but lacking in extended edges. Responding selectively to an extended edge – either a bright line on a dark background, or the reverse – highlights objects that are near or very large. Edge detectors are useful to a cat, because edges do not occur often in the background “noise” of the visual environment, which is of little consequence to the animal.
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