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the mirror-neuron system - UCSF Center for Integrative Neuroscience
the mirror-neuron system - UCSF Center for Integrative Neuroscience

... above, large portions of the parietal and premotor cortex. Second, there are other mechanisms that may mediate action recognition (see Rizzolatti et al. 2001). Third, vast lesions as those required to destroy the mirror neuron system may produce more general cognitive deficits that would render diff ...
Neuroscience 1b – Spinal Cord Dysfunction
Neuroscience 1b – Spinal Cord Dysfunction

...  The major difference between the main ascending sensory tracts is that fine touch information in the dorsal column tract is conveyed on the same side as it enters, whereas pain, temperature and crude touch via the spinothalamic tract is portrayed on the opposite side  The point at which the tract ...
Nervous System
Nervous System

... • The transfer of these electrical impulses over large distances is accomplished by the cells of the nervous system called neurons – capable of: • generating/initiating an electrical impulse • sending electrical impulses very rapidly from one location in the body to another • changing the resting me ...
Cells of the Brain
Cells of the Brain

... learn about the world around them and form memories of events that have taken place. Learning and memory formation alters the structure of the nervous system primarily by affecting the strength of particular synapses. Memories are stored in the brain in stages. Small pieces of new information are pr ...
The pattern of ocular dominance columns in macaque visual cortex
The pattern of ocular dominance columns in macaque visual cortex

... from the magnocellular layers of the geniculate (Hubel and Wiesel, '72). Layer 4C p is more densely cellular and contains fewer tangential fibers; it receives the bulk of the afferents from the parvocellular layers of the geniculate. Layer 4B contains a dense tangential fiber plexus, the stria of Ge ...
07.11 - UCSD Cognitive Science
07.11 - UCSD Cognitive Science

... limited to reduce the length of time the animal was under anesthesia and to minimize damage to the cortex. The motor response evoked at each stimulation site was determined by visual inspection and muscle palpation. The threshold current for each response was defined as the stimulus intensity that e ...
Protein Interacting with Never in Mitosis A
Protein Interacting with Never in Mitosis A

... stem cells capable of gliogenesis in degenerative disorders of the CNS. differentiating into a variety of cell lineages such as odontoblasts, osteoblasts, adipocytes, and hepatocytes (1–3). In addition, hDPSCs were able to differentiate into glial or neuronal cells on the basis of cellular morpholog ...
The neural milieu of the developing choroid plexus: neural stem
The neural milieu of the developing choroid plexus: neural stem

... 1978a,b,c; Edvinsson and Lindvall, 1978), but there is only one study where this issue was specifically addressed and that suggests that the CP becomes innervated postnatally (Lindvall and Owman, 1978). This seems peculiar, as innervation tends to occur at early stages of organ development, before a ...
Electrical Synapses in the Thalamic Reticular Nucleus
Electrical Synapses in the Thalamic Reticular Nucleus

... E xtracellular stimuli were delivered using bipolar stimulating electrodes, monopolar tungsten electrodes, and AC SF-filled glass electrodes. Data were collected and analyzed using a digital-to-analog board and Labview software (National Instruments, Austin, TX) on a personal computer (Dell Computer ...
Chapter 15 Viral Vector-Based Techniques for Optogenetic
Chapter 15 Viral Vector-Based Techniques for Optogenetic

... are also likely to influence the number of genome copies in transduced cells, leading to lower expression levels of the transgene in individual cells within the region [18]. On par with AAV2 transduction, LV transduction is more spatially restricted in vivo and can thus be used to target smaller stru ...
The spinothalamic tract: An examination of the cells of origin of the
The spinothalamic tract: An examination of the cells of origin of the

... cord lesion served to identify the lumbar and cervical cells of origin of the total spinothalamic tract (VSW and DSTT). WGA-HRP was used in three experiments (Controls 1, 2, and 31, whereas HRP-Sigma VI was used in two experiments (Controls 4 and 5). The distribution of label was examined in the cer ...
Computation by Oscillations: Implications of Experimental Data
Computation by Oscillations: Implications of Experimental Data

... To determine the dominant frequency of membrane potential oscillations, an automated script in MATLAB analyzed segments of membrane potential recorded near firing threshold (255, 250, 245, and 240 mV). Three second long windows that overlapped by 1.5 s were zero centered, and autocorrelations were p ...
THE SPINAL CORD Development of the Spinal Nerves (Fig.2) The
THE SPINAL CORD Development of the Spinal Nerves (Fig.2) The

... of the leg at the knee. At the same time as the quadriceps contracts there is a reciprocal inhibition of the antagonistic muscles, the flexors of the knee. The inhibition of the flexors is mediated by polysynaptic reflex arcs, and since the motor neurons for the flexors are located in more caudal s ...
Development of the Spinal Nerves
Development of the Spinal Nerves

... of the leg at the knee. At the same time as the quadriceps contracts there is a reciprocal inhibition of the antagonistic muscles, the flexors of the knee. The inhibition of the flexors is mediated by polysynaptic reflex arcs, and since the motor neurons for the flexors are located in more caudal s ...
How do Migraines Happen
How do Migraines Happen

... hallucinations immediately preceding some epileptic seizures; for 100 years or so, it has also been used to describe the onset of many mi­­ graines. (Epilepsy may occur in people with mi­­ graine, and vice versa; the reasons are under investigation.) The most common form of aura is a visual illusion ...
Insect olfactory memory in time and space
Insect olfactory memory in time and space

... Electrophysiological recordings have been widely used to study the cellular or neuronal circuitry changes that occur with learning in mammalian model systems. However, such recordings are difficult to perform in insects because of the small size of their bodies, brains and neurons. Progress with fun ...
Single Nigrostriatal Dopaminergic Neurons Form Widely Spread
Single Nigrostriatal Dopaminergic Neurons Form Widely Spread

... the SN (Fig. 1 A–A⬙,C–C⬙). Twenty-one of 70 neurons were positive for TH immunoreactivity. Finally, the hemiencephalic sections containing these dopaminergic neurons were further stained by the immunoperoxidase method with anti-GFP antibody (Fig. 1 B, D–G). Of the 21 stained neurons, the axons of 13 ...
Development of Subcellular mRNA Compartmentation in
Development of Subcellular mRNA Compartmentation in

... calmodulin-dependentprotein kinaseII, a major component of the postsynaptic membranespecialization (Burgin et al., 1990). Most other mRNAs whose subcellulardistributions have been evaluated are detectable only in neuronal cell bodiesand proximal dendrites.The most convincing evidence in support of t ...
Chapter 2: Communication Within the Nervous System
Chapter 2: Communication Within the Nervous System

... And it didn’t take long to discover that the real value of education isn’t just a ticket to a better job but all the learning along the way about life and the world and what makes both of them work. That is what led me, after trying one major after another, to discover psychology. A child of Sputnik ...
Bursting the unfolded protein response accelerates axonal
Bursting the unfolded protein response accelerates axonal

... peripheral nervous system (PNS) is damaged. These pathological state are are associated with weakness, pain, and loss of motor and sensory control. More than 100 types of peripheral neuropathies have been identified, with distinct symptoms and prognosis classified according to the type of damage to ...
Mechanisms of memory storage in a model perirhinal network
Mechanisms of memory storage in a model perirhinal network

... input cells distributed along the rostrocaudal extent of the perirhinal network. Each neocortical input formed unique connections with perirhinal neurons and could be activated independently. Note that these ‘‘input cells’’ are in fact just spike trains used for synaptic drive. To constrain the dist ...
Studying the Brain`s Structure and Functions: Spying on the Brain
Studying the Brain`s Structure and Functions: Spying on the Brain

... of the body. Made up of neurons with long axons and dendrites, the peripheral nervous system encompasses all the parts of the nervous system other than the brain and spinal cord. There are two major divisions—the somatic division and the autonomic division. The somatic division specializes in the co ...
BIO 154: Exam 2006
BIO 154: Exam 2006

... molecular mechanisms of synaptic transmission, aldicarb was used to perform a genetic screen. Aldicarb causes paralysis and eventually death. A) Use one or two sentences to explain the action of Aldicarb (2 pts) ...
Lecture 7 Rhythms of the Brain
Lecture 7 Rhythms of the Brain

... waking pattern of electrical activity in the cerebral cortex. Lesions caused sleep state. • RAS acts as the on/off switch for the brain. – On = conscious – Off = unconscious – Prolonged off state = coma ...
CHAPTER 14: THE AUTONOMIC NERVOUS SYSTEM AND
CHAPTER 14: THE AUTONOMIC NERVOUS SYSTEM AND

... Autonomic nervous system (ANS) is involuntary arm of peripheral nervous system (PNS); also known as visceral motor division  Divided into two separate divisions, sympathetic and parasympathetic nervous systems; constantly work together to maintain homeostasis  Oversees most vital functions includi ...
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Feature detection (nervous system)

Feature detection is a process by which the nervous system sorts or filters complex natural stimuli in order to extract behaviorally relevant cues that have a high probability of being associated with important objects or organisms in their environment, as opposed to irrelevant background or noise. Feature detectors are individual neurons – or groups of neurons – in the brain which code for perceptually significant stimuli. Early in the sensory pathway feature detectors tend to have simple properties; later they become more and more complex as the features to which they respond become more and more specific. For example, simple cells in the visual cortex of the domestic cat (Felis catus), respond to edges – a feature which is more likely to occur in objects and organisms in the environment. By contrast, the background of a natural visual environment tends to be noisy – emphasizing high spatial frequencies but lacking in extended edges. Responding selectively to an extended edge – either a bright line on a dark background, or the reverse – highlights objects that are near or very large. Edge detectors are useful to a cat, because edges do not occur often in the background “noise” of the visual environment, which is of little consequence to the animal.
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