Effects of Reversible Inactivation of the Primate Mesencephalic
... Waitzman, David M., Valentine L. Silakov, Stacy DePalmaBowles, and Amanda S. Ayers. Effects of reversible inactivation of the primate mesencephalic reticular formation. I. Hypermetric goaldirected saccades. J. Neurophysiol. 83: 2260 –2284, 2000. Singleneuron recording and electrical microstimulation ...
... Waitzman, David M., Valentine L. Silakov, Stacy DePalmaBowles, and Amanda S. Ayers. Effects of reversible inactivation of the primate mesencephalic reticular formation. I. Hypermetric goaldirected saccades. J. Neurophysiol. 83: 2260 –2284, 2000. Singleneuron recording and electrical microstimulation ...
Bischoff_Thesis_notes
... cerebellum may be specialized in using sensory information and acquiring in motor skills basal ganglia may be more involved in movements which are either internally generated or guided by external cues as well as the learning of sequential movements ...
... cerebellum may be specialized in using sensory information and acquiring in motor skills basal ganglia may be more involved in movements which are either internally generated or guided by external cues as well as the learning of sequential movements ...
![[Ca2+]c dynamics in spontaneously firing dopamine neurons of the](http://s1.studyres.com/store/data/003492398_1-2708bc56966b4cab721b0073b5bc49ec-300x300.png)
[Ca2+]c dynamics in spontaneously firing dopamine neurons of the
... It is well known that dopamine neurons in substantia nigra generate spontaneous firing in vivo, in vitro and even in isolated cells (Grace and Bunney, 1983a; Grace and Bunney, 1983b; Grace, 1988; Cardozo, 1993; Uchida et al., 2002). Thus, in order to test whether the neurons we isolated produce SAPs ...
... It is well known that dopamine neurons in substantia nigra generate spontaneous firing in vivo, in vitro and even in isolated cells (Grace and Bunney, 1983a; Grace and Bunney, 1983b; Grace, 1988; Cardozo, 1993; Uchida et al., 2002). Thus, in order to test whether the neurons we isolated produce SAPs ...
Mitochondrial support of persistent presynaptic vesicle mobilization
... mitochondria, while 18% were multisynaptic boutons with more than half (52%) containing mitochondria (from Table 2, Shepherd and Harris, 1998). Individual PSD areas were larger when presynaptic boutons contained a mitochondrion, although this effect did not reach statistical significance for multisy ...
... mitochondria, while 18% were multisynaptic boutons with more than half (52%) containing mitochondria (from Table 2, Shepherd and Harris, 1998). Individual PSD areas were larger when presynaptic boutons contained a mitochondrion, although this effect did not reach statistical significance for multisy ...
Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau
... Fig. 1h). It remains open if these tau containing particles are made exclusively of tau or contain other constituents such as proteins and lipids. Human tau species observed within primary neurons 2–5 days after exposure to rTg4510 brain extract were Alz50 positive (Fig. 1i, top) but negative for Th ...
... Fig. 1h). It remains open if these tau containing particles are made exclusively of tau or contain other constituents such as proteins and lipids. Human tau species observed within primary neurons 2–5 days after exposure to rTg4510 brain extract were Alz50 positive (Fig. 1i, top) but negative for Th ...
Theta Modulation in the Medial and the Lateral Entorhinal Cortices
... weights. The rats were trained on two behavioral paradigms using food reward (chocolate sprinkles). The first paradigm consisted of rats running clockwise on a circular track for 30 min looking for food rewards placed at arbitrary locations on the track (one to two rewards per lap); the second consi ...
... weights. The rats were trained on two behavioral paradigms using food reward (chocolate sprinkles). The first paradigm consisted of rats running clockwise on a circular track for 30 min looking for food rewards placed at arbitrary locations on the track (one to two rewards per lap); the second consi ...
Anandamide as an intracellular messenger regulating ion channel
... phosphorylation state of the channel. Indeed, anandamide has been shown previously to directly inhibit Shaker-related voltage sensitive K+ -channels at low micromolar concentrations [41]. Although the effect was shared by THC and other polyunsaturated Nacylethanolamines, it was insensitive towards b ...
... phosphorylation state of the channel. Indeed, anandamide has been shown previously to directly inhibit Shaker-related voltage sensitive K+ -channels at low micromolar concentrations [41]. Although the effect was shared by THC and other polyunsaturated Nacylethanolamines, it was insensitive towards b ...
A decade of the anaphase-promoting complex in the nervous system
... Kramer et al. 2000). Characterization of the functions and regulation of Cdh1–APC and Cdc20–APC in dividing cells has provided invaluable clues for our understanding of the novel functions and mechanisms of the anaphasepromoting complex in the nervous system. Identification of functions of the anaph ...
... Kramer et al. 2000). Characterization of the functions and regulation of Cdh1–APC and Cdc20–APC in dividing cells has provided invaluable clues for our understanding of the novel functions and mechanisms of the anaphasepromoting complex in the nervous system. Identification of functions of the anaph ...
Processing of Interaural Intensity Differences in the LSO: Role of
... whereas the inhibition is from globular bushy cells in the contralateral cochlear nucleus (Cant 1991; Cant and Casseday 1986; Caspary and Finlayson 1991; Grothe et al. 1994; Kuwabara et al. 1991; Smith et al. 1991; Zook and DiCaprio 1988). The globular bushy cells do not directly inhibit LSO cells, ...
... whereas the inhibition is from globular bushy cells in the contralateral cochlear nucleus (Cant 1991; Cant and Casseday 1986; Caspary and Finlayson 1991; Grothe et al. 1994; Kuwabara et al. 1991; Smith et al. 1991; Zook and DiCaprio 1988). The globular bushy cells do not directly inhibit LSO cells, ...
Martin, Neuroscientist 2005
... The corticospinal system connects the frontal and anterior parietal lobes with the spinal gray matter. Early in development, corticospinal neurons are distributed throughout much of the frontal and parietal lobes, and parts of the occipital and temporal lobes, but their distribution is later restric ...
... The corticospinal system connects the frontal and anterior parietal lobes with the spinal gray matter. Early in development, corticospinal neurons are distributed throughout much of the frontal and parietal lobes, and parts of the occipital and temporal lobes, but their distribution is later restric ...
neuronal reward and decision signals: from theories to data
... mediated by neuronal reward prediction error signals which implement basic constructs of reinforcement learning theory. These signals are found in dopamine neurons, which emit a global reward signal to striatum and frontal cortex, and in specific neurons in striatum, amygdala, and frontal cortex pro ...
... mediated by neuronal reward prediction error signals which implement basic constructs of reinforcement learning theory. These signals are found in dopamine neurons, which emit a global reward signal to striatum and frontal cortex, and in specific neurons in striatum, amygdala, and frontal cortex pro ...
neuropathology of dopamine systems in schizophrenia
... nigrostriatal and mesolimbic pathways, is the principal receptive region of the basal ganglia, which are a group of functionally related brain areas that include the striatum, SN, globus pallidus, and subthalamic nucleus. In the brain of primates and other higher mammals, the striatum can be divided ...
... nigrostriatal and mesolimbic pathways, is the principal receptive region of the basal ganglia, which are a group of functionally related brain areas that include the striatum, SN, globus pallidus, and subthalamic nucleus. In the brain of primates and other higher mammals, the striatum can be divided ...
After all, it`s still replication: A reply to Jacob on simulation and mirror
... More empirical evidence is needed in order to conclude that a process of mental simulation constitutes the causal basis of (some acts of) mindreading. The best place to look for this further evidence is probably the work of Goldman (see especially Goldman 2006, 2008). However, presenting and assessi ...
... More empirical evidence is needed in order to conclude that a process of mental simulation constitutes the causal basis of (some acts of) mindreading. The best place to look for this further evidence is probably the work of Goldman (see especially Goldman 2006, 2008). However, presenting and assessi ...
Actin in Axons: Stable Scaffolds and Dynamic Filaments
... functions, ABPs are the targets of extrinsic and intrinsic signaling pathways. ABPs are categorized by function: (1) sequester, or bind G-actin subunits; (2) nucleate actin polymerization; (3) cap F-actin barbed ends to inhibit polymerization; (4) cap pointed ends to inhibit depolymerization; (5) bi ...
... functions, ABPs are the targets of extrinsic and intrinsic signaling pathways. ABPs are categorized by function: (1) sequester, or bind G-actin subunits; (2) nucleate actin polymerization; (3) cap F-actin barbed ends to inhibit polymerization; (4) cap pointed ends to inhibit depolymerization; (5) bi ...
Prefrontal Projections to the Thalamic Reticular Nucleus
... rate, muscle tone, respiration, and pupillary dilatation were closely monitored. The monkeys were placed in a stereotaxic apparatus, and a small region of the cortex was exposed. Injection of neural tracers. In an effort to minimize animal numbers, injections of distinct neural tracers were made in ...
... rate, muscle tone, respiration, and pupillary dilatation were closely monitored. The monkeys were placed in a stereotaxic apparatus, and a small region of the cortex was exposed. Injection of neural tracers. In an effort to minimize animal numbers, injections of distinct neural tracers were made in ...
Electroencephalography - Department of Computational and
... potentials that the EEG records from the scalp, much the same way that economics can be studied from the level of a single individual's personal finances to the macro-economics of nations. Neurons, or nerve cells, are electrically active cells that are primarily responsible for carrying out the brai ...
... potentials that the EEG records from the scalp, much the same way that economics can be studied from the level of a single individual's personal finances to the macro-economics of nations. Neurons, or nerve cells, are electrically active cells that are primarily responsible for carrying out the brai ...
The Pedunculopontine Nucleus (PPN) in Parkinson`s Disease
... • There is a clear unmet need to develop novel therapeutic strategies to treat disabling levodopa and DBS resistant axial disturbances in PD. • Because the PPN is an integral component of the MLR there has been recent exploration of this novel target. • Suportingdata in animal studies sugges ...
... • There is a clear unmet need to develop novel therapeutic strategies to treat disabling levodopa and DBS resistant axial disturbances in PD. • Because the PPN is an integral component of the MLR there has been recent exploration of this novel target. • Suportingdata in animal studies sugges ...
Rapid Translocation of Zn 2+ from Nerve Terminals
... and Christopher J. Frederickson. Rapid translocation of Zn2⫹ from presynaptic terminals into postsynaptic hippocampal neurons after physiological stimulation. J Neurophysiol 86: 2597–2604, 2001. Zn2⫹ is found in glutamatergic nerve terminals throughout the mammalian forebrain and has diverse extrace ...
... and Christopher J. Frederickson. Rapid translocation of Zn2⫹ from presynaptic terminals into postsynaptic hippocampal neurons after physiological stimulation. J Neurophysiol 86: 2597–2604, 2001. Zn2⫹ is found in glutamatergic nerve terminals throughout the mammalian forebrain and has diverse extrace ...
Session 230 IOP Measurement and characterization I
... the orbital wall, and IOP was transmitted to the transducer via an aqueous-filled silicone tube inserted into the anterior chamber. The implant was large, and the battery required intraperitoneal placement. We have developed an updated bilateral IOP and ocular perfusion pressure (OPP) telemetry syst ...
... the orbital wall, and IOP was transmitted to the transducer via an aqueous-filled silicone tube inserted into the anterior chamber. The implant was large, and the battery required intraperitoneal placement. We have developed an updated bilateral IOP and ocular perfusion pressure (OPP) telemetry syst ...
Number, Density, and Surface/Cytoplasmic
... unchanged fluorescent intensity on the previously used imaging systems, indicating the stability of the His6– GFP solutions. For the present study, the beads were used to calibrate the Leica confocal microscope system. Using GFP-beads at densities at 300, 600, and 1500 GFP per square micrometer, we ...
... unchanged fluorescent intensity on the previously used imaging systems, indicating the stability of the His6– GFP solutions. For the present study, the beads were used to calibrate the Leica confocal microscope system. Using GFP-beads at densities at 300, 600, and 1500 GFP per square micrometer, we ...
Abstract of “Primate frontal eye fields mediate spatial attention in
... functionally different types of neurons have been identified in FEF. Movement neurons begin to fire approximately 50ms before the initiation of a saccadic eye movement (Bruce and Goldberg, 1985; Thompson et al., 1996). These neurons are thought to influence eye movements through projections to the s ...
... functionally different types of neurons have been identified in FEF. Movement neurons begin to fire approximately 50ms before the initiation of a saccadic eye movement (Bruce and Goldberg, 1985; Thompson et al., 1996). These neurons are thought to influence eye movements through projections to the s ...
Calcium Regulation of Dendritic Growth via CaM Kinase IV and
... presence of KCl stimulation. Note that overexpression of CaM kinase IV dramatically potentiates the effect of KCl depolarization on dendritic growth, indicating that intracellular CaM kinase IV levels are limiting for calcium-activated dendritic growth. (G) Quantification of the effects of expressin ...
... presence of KCl stimulation. Note that overexpression of CaM kinase IV dramatically potentiates the effect of KCl depolarization on dendritic growth, indicating that intracellular CaM kinase IV levels are limiting for calcium-activated dendritic growth. (G) Quantification of the effects of expressin ...
the role of zinc in the pathogenesis and treatment of central nervous
... mammals zinc containing vesicles were found mostly in the glutamatergic neurons in brain cortex, hippocampus and amygdala, brain compartments responsible for learning, memory, cognition and mood regulation (10, 23, 24). During the neuronal activity, when zinc with glutamate is released from synaptic ...
... mammals zinc containing vesicles were found mostly in the glutamatergic neurons in brain cortex, hippocampus and amygdala, brain compartments responsible for learning, memory, cognition and mood regulation (10, 23, 24). During the neuronal activity, when zinc with glutamate is released from synaptic ...
Molecular and Cellular Endocrinology Metabolic control of puberty
... actions and receptor(s) of obestatin has been the subject of intense controversy recently. Although in this review special emphasis will be made on the experimental evidence supporting a potential role of ghrelin in the modulation of puberty, it is important to emphasize as background information th ...
... actions and receptor(s) of obestatin has been the subject of intense controversy recently. Although in this review special emphasis will be made on the experimental evidence supporting a potential role of ghrelin in the modulation of puberty, it is important to emphasize as background information th ...