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Bioscreening, Biophotonics, and Micromanipulation
Bioscreening, Biophotonics, and Micromanipulation

... instrumentation with which these models are studied. In recent years, the advantages of using small invertebrate animals as model systems for human disease have become increasingly apparent, and have resulted in two Nobel Prizes in Physiology and Medicine during the last five years for studies condu ...
BIO 154: Exam 2006
BIO 154: Exam 2006

... You decide to continue this research and find two interesting mutants: ser-3 appears to contain a loss-offunction mutation (unfed worms do not exhibit starvation phenotype) and egl-30 appears to have a gainof-function mutation (fed worms appear to be in starvation mode constitutively). You find that ...
$doc.title

... a  highly  immature  state.  Many  scientists  considered  this  impossible,  or  at  the  very  least,  that  it  would   require  very  complex  reorganization  in  the  cell  to  unlock  the  differentiated  state.  Such  was  the  s ...
Way SW, McKenna J 3rd, Mietzsch U, Reith RM, Wu HC, Gambello MJ. Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse. Human Molecular Genetics. 2009 Apr 1; 18(7):1252-65.
Way SW, McKenna J 3rd, Mietzsch U, Reith RM, Wu HC, Gambello MJ. Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse. Human Molecular Genetics. 2009 Apr 1; 18(7):1252-65.

... human disease and will be useful to dissect out the functions of the TSC complex in different neuronal populations. Nonetheless, neither model has tested the hypothesis that loss of Tsc1 or Tsc2 in a neuroprogenitor cell initiates TSC neuropathology. Moreover, these studies are all based upon the Ts ...
Genome wide expression profiling of the
Genome wide expression profiling of the

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The Nervous System - El Camino College
The Nervous System - El Camino College

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A lineage-related reciprocal inhibition circuitry for sensory
A lineage-related reciprocal inhibition circuitry for sensory

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5. Discussion - UvA-DARE - University of Amsterdam
5. Discussion - UvA-DARE - University of Amsterdam

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From view cells and place cells to cognitive map learning
From view cells and place cells to cognitive map learning

... de®cits in humans and nonhuman primates (Kolb and Tees 1990). The PPC de®cit is likely to be dissociable from the frontal or hippocampal de®cits in that there is no additional memory de®cit after PPC lesions. From the anatomical data, it is not possible to say that complex object recognition cannot ...
File - Ms Curran`s Leaving Certificate Biology
File - Ms Curran`s Leaving Certificate Biology

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Michael Arbib: CS564 - Brain Theory and Artificial Intelligence
Michael Arbib: CS564 - Brain Theory and Artificial Intelligence

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Stem cell factor induces outgrowth of c-kit-positive
Stem cell factor induces outgrowth of c-kit-positive

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hydroxytryptamine-containing neurons in the snail Effect of
hydroxytryptamine-containing neurons in the snail Effect of

... 48h resulted in increases of up to 114% in tyrosine hydroxylase activity. Similar increases in the Na+ concentration of the medium had no significant effect on this enzyme activity. The response was obtained both in the presence and in the absence of the nerve growth factor isolated from adult male ...
retina - Bakersfield College
retina - Bakersfield College

... • In lower layer IV of the striate cortex, neurons with circular receptive fields (as in retinal ganglion cells and LGN) are rare • Most neurons in V1 are either – Simple – receptive fields are rectangular with “on” and “off” regions, or – Complex – also rectangular, larger receptive fields, respond ...
What drives the plasticity of brain tissues?
What drives the plasticity of brain tissues?

... unilaterally-trained animals tie in Gilbert work on interhemispheric changes via horizontal connections??? do you not want to mention the forked-apicals? ...
Tangential Networks of Precocious Neurons and Early Axonal
Tangential Networks of Precocious Neurons and Early Axonal

... bipolar cells had their cell bodies and processes extending radially: these might represent postmitotic neurons migrating from the VZ of the basal telencephalon to the pial surface. However, many had tangentially oriented somata and long, tangential processes, suggesting that they might be migrating ...
Exome sequencing identified RPS15A as a novel
Exome sequencing identified RPS15A as a novel

... Several studies showed that the heterozygous mutations in RP genes observed in DBA disturb the synthesis of either the small or large subunit through defects in pre-ribosomal RNA (pre-rRNA) processing.6,8,9,15 To determine if the haploinsufficiency for RPS15A would affect pre-rRNA processing in eryt ...
make motor neuron posters now
make motor neuron posters now

... permeability. Na+ rushes inward and intracellular fluid becomes more positive (DEPOLARIZATION). ...
neural basis of deciding, choosing and acting
neural basis of deciding, choosing and acting

Primary afferent neurons of the gut
Primary afferent neurons of the gut

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Regional Specialization of the Membrane of Retinal Glial Cells and
Regional Specialization of the Membrane of Retinal Glial Cells and

... the Muller cell surface has been tested in a number of ways using intracellular recordings from in situ and dissociated amphibian Miiller cells. The most direct test of the hypothesis has come from input-impedance measurements on dissociated salamander Muller cells. If a large fraction of the K+ con ...
Chapter 12
Chapter 12

From Network Architecture of Forebrain Systems to Brain Wide Web
From Network Architecture of Forebrain Systems to Brain Wide Web

... studies, using animal models of human disease. Limbic system with related networks was the prime theme of her presentation, with main emphasize placed on the complex interplay between the glutamatergic, GABAergic and dopaminergic circuits. Recent evidence from her group suggests that a deficit in mu ...
Microconnectomics of the Pretectum and Ventral Thalamus in the
Microconnectomics of the Pretectum and Ventral Thalamus in the

... eye orienting movements (Pateromichelakis, 1979; Guiloff et al., 1987; Gioanni et al., 1991). Apart from these general studies, detailed cellular morphology and connectivity of these nuclei both between them and with other visual structures remains unclear. This might be to some extent due to techni ...
Communication as an emergent metaphor for neuronal operation
Communication as an emergent metaphor for neuronal operation

... Relationships between real life objects or events are often far more complex for Euclidean spaces and smooth mappings between them to be the most appropriate representations. In reality it is usually the case that objects are comparable only to some objects in the world, but not to all. In other wo ...
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Channelrhodopsin



Channelrhodopsins are a subfamily of retinylidene proteins (rhodopsins) that function as light-gated ion channels. They serve as sensory photoreceptors in unicellular green algae, controlling phototaxis: movement in response to light. Expressed in cells of other organisms, they enable light to control electrical excitability, intracellular acidity, calcium influx, and other cellular processes. Channelrhodopsin-1 (ChR1) and Channelrhodopsin-2 (ChR2) from the model organism Chlamydomonas reinhardtii are the first discovered channelrhodopsins. Variants have been cloned from other algal species, and more are expected.
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