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OverviewCerebellum
OverviewCerebellum

... the phase of the eye movement with respect to the vestibular stimulation; for the eyeblink it controls the time of the eyeblink with respect to the tone. The cerebellum can change this temporal relation. Many, but not all, neuroscientists believe that this form of learning is based on P cell plastic ...
Information About Spatial View in an Ensemble of Primate
Information About Spatial View in an Ensemble of Primate

Adrenergic System
Adrenergic System

... There are three steps to prove or discover a receptor: 1) Structure-Activity Analyses. 2) Careful comparison of potency with series of agonists and antagonists. 3) Molecular biology provides a new approach by making possible the discovery and expression of genes that code for related receptors. So, ...
Multiple functional domains are involved in tomosyn regulation of
Multiple functional domains are involved in tomosyn regulation of

MicroRNA ablation affects Bergmann glial morphology and disrupts
MicroRNA ablation affects Bergmann glial morphology and disrupts

... MicroRNAs (miRNAs) play important roles during development of the central nervous system (CNS). Several reports indicate that tissue development and cellular differentiation in the developing forebrains are disrupted in the absence of miRNAs. However, miRNA functions during cerebellar development ha ...
Decoding Complete Reach and Grasp Actions from Local Primary
Decoding Complete Reach and Grasp Actions from Local Primary

... in M1 can facilitate the movement of both proximal and distal joints (Donoghue et al., 1992; McKiernan et al., 1998; Park et al., 2001). Recent M1 recordings in humans with tetraplegia show that nearby neurons are engaged by imagined proximal and distal actions (Hochberg et al., 2006). Understanding ...
Processing in layer 4 of the neocortical circuit: new insights from
Processing in layer 4 of the neocortical circuit: new insights from

... based on the arrangement of a cell’s ON and OFF subregions [26]. However, the feed-forward model predicts that inhibition and threshold sharpen spike tuning relative to voltage tuning; it is voltage tuning that would be expected to follow a linear prediction. Ferster’s group tested this by mapping t ...
Effects of the Abused Inhalant Toluene on the
Effects of the Abused Inhalant Toluene on the

... Firing of VTA DA neurons is strongly suppressed via activation of D2 dopamine receptors and this feature is often used to identify putative DA neurons during in vitro and in vivo recordings. However, there is now a convincing evidence that D2 modulation of firing is produced in only a subpopulation ...
Impaired odour discrimination on desynchronization of odour
Impaired odour discrimination on desynchronization of odour

... a behavioural paradigm. Using honeybees, we now demonstrate that odour encoding involves, as it does in locusts, the oscillatory synchronization of assemblies of projection neurons and that this synchronization is also selectively abolished by picrotoxin, an antagonist of the GABAA (g-aminobutyric a ...
D. What Causes Multiple Sclerosis?
D. What Causes Multiple Sclerosis?

... system (CNS). The CNS consists of the brain, spinal cord, and the optic nerves. Surrounding and protecting the nerve fibers of the CNS is a fatty tissue called myelin, which helps nerve fibers conduct electrical impulses. Multiple sclerosis was first recognized as a disorder in the late nineteenth c ...
Phase IIB / PHGY 825 Organization of the Brain Stem Organization
Phase IIB / PHGY 825 Organization of the Brain Stem Organization

... projections. They may innervate multiple levels of the spinal cord, send collaterals to the brainstem and diencephalon, have bifurcating axons that give rise to both ascending and descending connections. They may also have large dendritic fields that allow them to receive synaptic inputs from ascend ...
Parallel Fibers Synchronize Spontaneous Activity in Cerebellar
Parallel Fibers Synchronize Spontaneous Activity in Cerebellar

... Golgi cells play an important role in cerebellar f unction, because they are the only element within the circuit that regulates granule cell activity (Eccles et al., 1964) (Fig. 1 A). Feedback inhibition exerted by Golgi cells may set the activation threshold for granule cell firing, thus retaining ...
Ch16.Special.Senses
Ch16.Special.Senses

... – Receptors are not free endings of sensory neurons – Special receptor cells! • Neuron-like epithelial cells or small peripheral neurons – Transfer sensory information to other neurons in afferent pathways ...
10 - Computing and Cybernetics in the Soviet Union.pptx
10 - Computing and Cybernetics in the Soviet Union.pptx

... John von Neumann ...
Regulation of neuronal survival and death by extracellular signals
Regulation of neuronal survival and death by extracellular signals

... vertebrate nervous system, affecting neurons, glial cells and their progenitors. The most extensively studied and best understood phase of cell death occurs in populations of neurons shortly after they begin establishing connections with other neurons and/or non-neural tissues. This phase of cell de ...
Neural and Computational Mechanisms of Action Processing
Neural and Computational Mechanisms of Action Processing

... recognition mechanisms (see the Section ‘Theoretical models’). However, it has to be noted that the same population of neurons can be simultaneously tuned to multiple parameters, e.g. to the view and different grip types. In addition, individual neurons can show different degrees of invariance with ...
(SCI) patients in the United States
(SCI) patients in the United States

Consciousness Operates Beyond the Timescale
Consciousness Operates Beyond the Timescale

... the cytoskeleton. The proposed model in which the consciousness is localized in coherently organized brain cortical cytoskeletons is not fully incompatible with the current neural network paradigm indeed it extends it, showing input of information from the membrane electric activity down to the cyto ...
PDF
PDF

... in a specific language format, that the information would be of no practical use unless transmitted and its meaning understood by a second neuron. Therefore, it was proposed that two neurons are required for communication, and further, that their shared ­dendritic–synaptic–dendritic (DSD) field cont ...
Nervous System Organization
Nervous System Organization

...  You touch a hot stove and jerk your hand back. Sensory input, integration, motor output ...
A Pitx transcription factor controls the establishment
A Pitx transcription factor controls the establishment

... 2008b; Nishimura et al., 2010). Learning more about the differentiation processes in planarians could therefore provide valuable insights into the basic mechanisms of disease and might reveal new conserved drug targets. However, it is currently unclear whether a distinct population of adult neural s ...
Red Blood Cells Classification using Image
Red Blood Cells Classification using Image

(30 MCQ answers). - Blackwell Publishing
(30 MCQ answers). - Blackwell Publishing

... 12) Answers: (a) and (b). If we eat food containing lots of energy (e.g. rich in fat) for a few days, we gradually eat less of it. If we eat food with little energy, we gradually, over days, ingest more of it. This regulation involves learning to associate the sight, taste, smell and texture of the ...
Get PDF - Wiley Online Library
Get PDF - Wiley Online Library

... Marshall Stoneham, recently analysed Turin’s theory and found that it is consistent with the underlying physics and with known features of smell (Brookes et al, 2007). “The full significance of Luca Turin’s idea that we investigated in the paper […] can only be judged properly after more experimenta ...
Restoring axonal localization and transport of transmembrane
Restoring axonal localization and transport of transmembrane

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Channelrhodopsin



Channelrhodopsins are a subfamily of retinylidene proteins (rhodopsins) that function as light-gated ion channels. They serve as sensory photoreceptors in unicellular green algae, controlling phototaxis: movement in response to light. Expressed in cells of other organisms, they enable light to control electrical excitability, intracellular acidity, calcium influx, and other cellular processes. Channelrhodopsin-1 (ChR1) and Channelrhodopsin-2 (ChR2) from the model organism Chlamydomonas reinhardtii are the first discovered channelrhodopsins. Variants have been cloned from other algal species, and more are expected.
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