Therapeutic Drug Monitoring of Antiepileptic Drugs in the 21st Century
... initiation, dosage modification, or introduction/interruption of an interacting drug. Co-medications should be known when interpreting a drug level, as well as the stage of a possible ongoing pregnancy. Other aspects also of importance, but usually of less concern in outpatient practice, are accurat ...
... initiation, dosage modification, or introduction/interruption of an interacting drug. Co-medications should be known when interpreting a drug level, as well as the stage of a possible ongoing pregnancy. Other aspects also of importance, but usually of less concern in outpatient practice, are accurat ...
enclosure-v
... with metastatic RCC who progressed after immunotherapy. Expanded-access studies in europe and north america showed the safety and efficacy of sorafenib in special populations such as elderly, renal failure and cerebral metastases, as well as patients with no prior therapy. No cross-resistance has be ...
... with metastatic RCC who progressed after immunotherapy. Expanded-access studies in europe and north america showed the safety and efficacy of sorafenib in special populations such as elderly, renal failure and cerebral metastases, as well as patients with no prior therapy. No cross-resistance has be ...
System suitability test
... Chirality exists everywhere in nature and plays a significant role in a number of aspects of our life. The consideration of the aspect of chirality is very important for the environment, as well as for some industries, more concretely for the pharmaceutical industry. More than half of the medicines ...
... Chirality exists everywhere in nature and plays a significant role in a number of aspects of our life. The consideration of the aspect of chirality is very important for the environment, as well as for some industries, more concretely for the pharmaceutical industry. More than half of the medicines ...
EVALUATION OF REPAGLINIDE ENCAPSULATED NANOPARTICLES PREPARED BY SONICATION METHOD Research Article
... the viscosity of internal phase increased the diffusion rate was also decreased in external aqueous phase or difficult to disperse due to resistance in higher mass transfer and resulted in larger droplets gives more particle size than lower viscous internal phase (*p<0.05) [13]. At lower ratio the p ...
... the viscosity of internal phase increased the diffusion rate was also decreased in external aqueous phase or difficult to disperse due to resistance in higher mass transfer and resulted in larger droplets gives more particle size than lower viscous internal phase (*p<0.05) [13]. At lower ratio the p ...
bioavailability enhancdement of poorly soluble drugs by smedds
... Oral route has always been the favorite route of drug administration in many diseases and till today it is the first way investigated in the development of new dosage forms. The major problem in oral drug formulations is low and erratic bioavailability, which mainly results from poor aqueous solubil ...
... Oral route has always been the favorite route of drug administration in many diseases and till today it is the first way investigated in the development of new dosage forms. The major problem in oral drug formulations is low and erratic bioavailability, which mainly results from poor aqueous solubil ...
ANTI-INFLAMMATORY EFFECT OF THE SERRATIOPEPTIDASE
... dangerous. US FDA regularly serves notices to marketing of the drugs which are not approved. It even serves notices to online marketing websites (17). It is requirement of US FDA to do at least one placebo controlled clinical study to get approval for the marketing. However in India such norms are r ...
... dangerous. US FDA regularly serves notices to marketing of the drugs which are not approved. It even serves notices to online marketing websites (17). It is requirement of US FDA to do at least one placebo controlled clinical study to get approval for the marketing. However in India such norms are r ...
Pharmaceutical Price Policies and Practices in China
... Note: in column 3, figures are first given in billion Yuan and then in billion US$ equivalent. ...
... Note: in column 3, figures are first given in billion Yuan and then in billion US$ equivalent. ...
Foundation - The Learning Oasis
... European cities. Scientists began to share their research by publishing their work in journals. During this time, William Harvey discovered how blood circulated through the body and Edward Jenner invented a vaccination for smallpox after discovering the relationship between cowpox and smallpox. Each ...
... European cities. Scientists began to share their research by publishing their work in journals. During this time, William Harvey discovered how blood circulated through the body and Edward Jenner invented a vaccination for smallpox after discovering the relationship between cowpox and smallpox. Each ...
A Review on Mouth Dissolving Film
... considered as an ultra thin strip of postage stamp size with an active pharmaceutical ingredient and other excipients. Most fast dissolving films are having taste masked active ingredients. These masked active ingredients are swallowed by the saliva of patients along with the soluble and insoluble e ...
... considered as an ultra thin strip of postage stamp size with an active pharmaceutical ingredient and other excipients. Most fast dissolving films are having taste masked active ingredients. These masked active ingredients are swallowed by the saliva of patients along with the soluble and insoluble e ...
Sublingual drug delivery system List of contents
... Thin film drug delivery is a process of delivering drugs to the systemic circulation via a thin film that dissolves when in contact with liquid, often referred to as a dissolving film or strip. thin film strips are typically designed for oral administration, with the user placing the strip on or und ...
... Thin film drug delivery is a process of delivering drugs to the systemic circulation via a thin film that dissolves when in contact with liquid, often referred to as a dissolving film or strip. thin film strips are typically designed for oral administration, with the user placing the strip on or und ...
STERILE COMPOUNDING AND PREPARATIONS A Knowledge
... The level of difficulty of preparing the compounding prescriptions is determined by the physical properties of the drug being prescribed and the dosage form desired either by the prescriber or patient. In some cases compounding will be a simple two-step process, whereas in others it will require ext ...
... The level of difficulty of preparing the compounding prescriptions is determined by the physical properties of the drug being prescribed and the dosage form desired either by the prescriber or patient. In some cases compounding will be a simple two-step process, whereas in others it will require ext ...
A mathematical model for maximizing the value of phase 3
... The key advantage of our model is that it integrates knowledge from experts in diverse areas of expertise such as clinical research, trial management, clinical operations, statistics, financial analysis, and marketing. The IP formulation is rich in scope and provides the basic framework for quantita ...
... The key advantage of our model is that it integrates knowledge from experts in diverse areas of expertise such as clinical research, trial management, clinical operations, statistics, financial analysis, and marketing. The IP formulation is rich in scope and provides the basic framework for quantita ...
Pharmaceutical Applications of Ispaghula Husk
... genitourinary tracts, duodenal ulcer, gonorrhea, piles, etc., as bulk forming, non-irritant laxative drug, demulcent, as a cervical dilator etc1-2. Drugs are rarely administered solely as pure chemical substances, but are almost given in the form of drug delivery system 3(DDS). ...
... genitourinary tracts, duodenal ulcer, gonorrhea, piles, etc., as bulk forming, non-irritant laxative drug, demulcent, as a cervical dilator etc1-2. Drugs are rarely administered solely as pure chemical substances, but are almost given in the form of drug delivery system 3(DDS). ...
Nasal Drug Delivery in EMS
... Nasal drug delivery is convenient and easy, but it may not always be effective. Nasal drug delivery cannot completely replace the need for injections. Being aware of the limitations and using the correct equipment and drug concentrations will assist you in predicting times when nasal drug delivery m ...
... Nasal drug delivery is convenient and easy, but it may not always be effective. Nasal drug delivery cannot completely replace the need for injections. Being aware of the limitations and using the correct equipment and drug concentrations will assist you in predicting times when nasal drug delivery m ...
Options for regulating new psychoactive drugs: a review of
... is essentially impossible at the stage the decision is called for. This is discussed in detail below. ...
... is essentially impossible at the stage the decision is called for. This is discussed in detail below. ...
FAST DISINTEGRATING TABLETS: AN OVERVIEW OF FORMULATION AND TECHNOLOGY Review Article SIRAJ SHAIKH ,R.V.KHIRSAGAR
... Recent development in fast disintegrating technology mainly works to improve the disintegration quality of these delicate dosage forms without affecting their integrity. This article focuses on the patented technologies available and the advances made so far in the field of fabrication of fast ...
... Recent development in fast disintegrating technology mainly works to improve the disintegration quality of these delicate dosage forms without affecting their integrity. This article focuses on the patented technologies available and the advances made so far in the field of fabrication of fast ...
Memorandum
... 7.3 “PhaseII:SambongTablet as anti-urolithiasis,”7.4, “PhaseIII clinical Trial of Blumea balsamzjkr L (Sambong)tablet in the treatment of urinary tract stone: a randomizeddoubleblind placebo-controlledstudy”, and 7.5 “Extended PhaseIII Open Trial of Blumea balsamzjk L (Sambong)for the treatmentof ur ...
... 7.3 “PhaseII:SambongTablet as anti-urolithiasis,”7.4, “PhaseIII clinical Trial of Blumea balsamzjkr L (Sambong)tablet in the treatment of urinary tract stone: a randomizeddoubleblind placebo-controlledstudy”, and 7.5 “Extended PhaseIII Open Trial of Blumea balsamzjk L (Sambong)for the treatmentof ur ...
pH TRIGGERED DRUG DELIVERY OF ORNIDAZOLE FROM EUDRAGIT COATED CHITOSAN MICROSPHERE:
... Microspheres are sometimes referred to as micro particles. Microspheres can bemanufactured from various natural and synthetic materials. Various natural and synthetic polymers used are Agarose, carrageenan, chitosan, starch, albumin, collagen, poly alkyl cyano acrylates, poly anhydrides, poly methyl ...
... Microspheres are sometimes referred to as micro particles. Microspheres can bemanufactured from various natural and synthetic materials. Various natural and synthetic polymers used are Agarose, carrageenan, chitosan, starch, albumin, collagen, poly alkyl cyano acrylates, poly anhydrides, poly methyl ...
PHARMACEUTICAL STUDIES ON FLASH TABLETS OFA HIGHLY SOLUBLE METFORMIN HYDROCHLORIDE
... thiazolidinediones and sulphonylurea contribute to weight gain, whereas metformin causes weight loss and dipeptidyl peptidase-4 inhibitors are weight neutral[16,17].Overall, there is a need for novel agents which can effectively control blood sugar level without producing weight gain or hypoglycemia ...
... thiazolidinediones and sulphonylurea contribute to weight gain, whereas metformin causes weight loss and dipeptidyl peptidase-4 inhibitors are weight neutral[16,17].Overall, there is a need for novel agents which can effectively control blood sugar level without producing weight gain or hypoglycemia ...
Principles of Pharmacology
... -First pass metabolism Drug must pass through GI tract and liver before entering circulation and therefore are subject to metabolism meaning higher doses are given orally e.g. morphine -Food and GI motility affects absorption – must comply with instructions e.g. with food or on empty stomach -Can be ...
... -First pass metabolism Drug must pass through GI tract and liver before entering circulation and therefore are subject to metabolism meaning higher doses are given orally e.g. morphine -Food and GI motility affects absorption – must comply with instructions e.g. with food or on empty stomach -Can be ...
a review on dosage regimen - Indian Journal of Pharmaceutical
... Because of reasonable homogeneity in humans, the dosage regimens are calculated on population basis. However, same dose of a drug may produce large difference in pharmacological response in different individuals. This is called as intersubject variability. In other words, it means that the dose requ ...
... Because of reasonable homogeneity in humans, the dosage regimens are calculated on population basis. However, same dose of a drug may produce large difference in pharmacological response in different individuals. This is called as intersubject variability. In other words, it means that the dose requ ...
FORMULATION AND EVALUATION OF FLOATING CONTROLLED RELEASE TABLETS OF
... Almost all the drugs which are active orally are marketed as tablets, capsules or both. Prior to development of dosage forms with a new drug candidate, it is essential that certain fundamental physical and chemical properties of the drug molecule and other derived properties of the drug powder are d ...
... Almost all the drugs which are active orally are marketed as tablets, capsules or both. Prior to development of dosage forms with a new drug candidate, it is essential that certain fundamental physical and chemical properties of the drug molecule and other derived properties of the drug powder are d ...
Chapter 26 outline
... Garlic, gingko biloba, and feverfew can increase the risk for bleeding when taken in conjunction with antiplatelet drugs or anticoagulants Ma huang contains ephedrine and can increase heart rate when given with sympathomimetic drugs St. John’s wort can induce the 3A3/4 isoenzyme of the cytochrome P- ...
... Garlic, gingko biloba, and feverfew can increase the risk for bleeding when taken in conjunction with antiplatelet drugs or anticoagulants Ma huang contains ephedrine and can increase heart rate when given with sympathomimetic drugs St. John’s wort can induce the 3A3/4 isoenzyme of the cytochrome P- ...
Basic Principles of GMP
... For of these prescribed drugs,80% are reported to be used in accordance with their label and with conventional DF, not at all specifically adapted to the children use. The dose of API is fixed by using empirically established dosage regimen and the dose combination is sometimes largely used, whi ...
... For of these prescribed drugs,80% are reported to be used in accordance with their label and with conventional DF, not at all specifically adapted to the children use. The dose of API is fixed by using empirically established dosage regimen and the dose combination is sometimes largely used, whi ...