Physicians` attitude towards voluntary reporting of adverse drug
... advantage of covering a large number of patients and a wide range of drugs. Taking all these in consideration, any new marketed drug and those that are already well established, should be closely monitored in order to detect any new, unexpected or serious ADRs. In order to clarify some terms used in ...
... advantage of covering a large number of patients and a wide range of drugs. Taking all these in consideration, any new marketed drug and those that are already well established, should be closely monitored in order to detect any new, unexpected or serious ADRs. In order to clarify some terms used in ...
SOLUBILITY AND DISSOLUTION ENHANCEMENT OF POORLY WATER SOLUBLE GLIMEPIRIDE
... slightly increased to 0.02 mg/ml. These poorlywater soluble drugs provide challenges to deliver them in an active and absorbable form to the desired absorption site using physiologically safe excipients1, 2. Therefore, one of the most important steps in the development of dosage forms for these drug ...
... slightly increased to 0.02 mg/ml. These poorlywater soluble drugs provide challenges to deliver them in an active and absorbable form to the desired absorption site using physiologically safe excipients1, 2. Therefore, one of the most important steps in the development of dosage forms for these drug ...
PDF - International Journal of Pharma and Bio Sciences
... resulting in regulated and controlled release for a given time from all the batches. Swelling index increased with increase in concentration of modified gum karaya. The drug release mechanism was confirmed by Korsmeyer-Peppas exponential equation. It was also observed that among the four batches, th ...
... resulting in regulated and controlled release for a given time from all the batches. Swelling index increased with increase in concentration of modified gum karaya. The drug release mechanism was confirmed by Korsmeyer-Peppas exponential equation. It was also observed that among the four batches, th ...
FIXED DOSE COMBINATION PRODUCTSOF ANTI-HYPERTENSIVE’SAND ANTI-DIABETIC’S -
... Fixed Dose Combination (FDC) products are medicines that contain two or more active ingredients in a fixed ratio of doses in the same formulation [1, 2]. FDCs are formulated to have a similar bioequivalence of the two agents as separate tablets and therefore have similar pharmacokinetic and pharmaco ...
... Fixed Dose Combination (FDC) products are medicines that contain two or more active ingredients in a fixed ratio of doses in the same formulation [1, 2]. FDCs are formulated to have a similar bioequivalence of the two agents as separate tablets and therefore have similar pharmacokinetic and pharmaco ...
DEPARTMENT OF HEALTH AND HUMAN ... Food and Drug Administratiqn
... However, after the Panel submitted its report, FDA became aware o discussed studies indicating that certain dosages of phe~ylpr~p~o~amine cause blood pressure elevation (47 FR 8466). Therefore, in the p&amble to the Panel’s report, FDA specifically requested: data and information on the extent to wh ...
... However, after the Panel submitted its report, FDA became aware o discussed studies indicating that certain dosages of phe~ylpr~p~o~amine cause blood pressure elevation (47 FR 8466). Therefore, in the p&amble to the Panel’s report, FDA specifically requested: data and information on the extent to wh ...
Opiate Abuse 2011
... receiving opioids, nonmedical use of other psychotherapeutic drugs (in this article the category of psychotherapeutics includes pain relievers, tranquilizers, stimulants, and sedatives, but does not include over-the-counter drugs), emergency department visits for prescription controlled drugs, explo ...
... receiving opioids, nonmedical use of other psychotherapeutic drugs (in this article the category of psychotherapeutics includes pain relievers, tranquilizers, stimulants, and sedatives, but does not include over-the-counter drugs), emergency department visits for prescription controlled drugs, explo ...
MOLLY- "NOT YOUR BEST FRIEND"
... undergoes hepatic metabolism mediated by COMT and CYP2D6 to form MDA and several other metabolites. MDMA is eliminated majorly through the urinary route. Detection windows for MDMA in urine and oral fluid are 1-3 days and 1 day, respectively. Molly is promoted as a highly purified version of MDMA, a ...
... undergoes hepatic metabolism mediated by COMT and CYP2D6 to form MDA and several other metabolites. MDMA is eliminated majorly through the urinary route. Detection windows for MDMA in urine and oral fluid are 1-3 days and 1 day, respectively. Molly is promoted as a highly purified version of MDMA, a ...
The over-the-counter pharmaceutical market - policy and practice
... (antacids and antiulcer) and dermatological products. As with prescribed medicines, knowledge of all factors required for ‘safe’, clinically effective supply does not necessarily translate into practice. For OTC sales the pharmacy staff (pharmacists and nonpharmacists) must have all the knowledge, t ...
... (antacids and antiulcer) and dermatological products. As with prescribed medicines, knowledge of all factors required for ‘safe’, clinically effective supply does not necessarily translate into practice. For OTC sales the pharmacy staff (pharmacists and nonpharmacists) must have all the knowledge, t ...
drug–protein complexes
... Pharmacology for Nursing: A Pathophysiology Approach, Fourth Edition Michael Patrick Adams | Leland N. Holland | Carol Urban ...
... Pharmacology for Nursing: A Pathophysiology Approach, Fourth Edition Michael Patrick Adams | Leland N. Holland | Carol Urban ...
A NEW TOPICAL FLUCONAZOLE MICROSPONGE LOADED HYDROGEL: PREPARATION AND CHARACTERIZATION Research Article
... The aim of the present study was to formulate topical microsponge-based delivery system containing FLZ for controlled release of the drug and consequently avoiding its oral side effects. Ethyl cellulose (EC) and Eudragit RS 100 based microsponges were prepared using quasi-emulsion solvent diffusion ...
... The aim of the present study was to formulate topical microsponge-based delivery system containing FLZ for controlled release of the drug and consequently avoiding its oral side effects. Ethyl cellulose (EC) and Eudragit RS 100 based microsponges were prepared using quasi-emulsion solvent diffusion ...
PREPARATION AND EVALUATION OF FLUOXEITINE HYDROCHLORIDE ORAL DISPERSIBLE TABLETS Research Article
... avoidance, versatility and most importantly patient compliance. Recent advances in novel drug delivery systems aim to enhance safety and efficacy of drug molecule by formulation and to achieve better patient compliance. One such approach is ‘mouth dissolving tablets’. Their growing importance was un ...
... avoidance, versatility and most importantly patient compliance. Recent advances in novel drug delivery systems aim to enhance safety and efficacy of drug molecule by formulation and to achieve better patient compliance. One such approach is ‘mouth dissolving tablets’. Their growing importance was un ...
Summit: Setting a Research Agenda for Patient Safety
... and the use of alternate medications to improve care and decrease errors. In the only study documenting the epidemiology of medication errors in a children's hospital setting, Rainu Kaushal, MD and her colleagues found that serious pediatric medication errors (potential adverse drug events and preve ...
... and the use of alternate medications to improve care and decrease errors. In the only study documenting the epidemiology of medication errors in a children's hospital setting, Rainu Kaushal, MD and her colleagues found that serious pediatric medication errors (potential adverse drug events and preve ...
Nomenclature Guideline Outline
... In the United States under the Federal Food, Drug, and Cosmetic Act (FDCA), the official name given a drug plays a critical role. The FDCA defines the term ‘official compendium’ as the official USP, the official NF, or any supplement to them. A drug (which includes both FDCA drugs and Public Health ...
... In the United States under the Federal Food, Drug, and Cosmetic Act (FDCA), the official name given a drug plays a critical role. The FDCA defines the term ‘official compendium’ as the official USP, the official NF, or any supplement to them. A drug (which includes both FDCA drugs and Public Health ...
Nomenclature Guideline Outline
... In the United States under the Federal Food, Drug, and Cosmetic Act (FDCA), the official name given a drug plays a critical role. The FDCA defines the term ‘official compendium’ as the official USP, the official NF, or any supplement to them. A drug (which includes both FDCA drugs and Public Health ...
... In the United States under the Federal Food, Drug, and Cosmetic Act (FDCA), the official name given a drug plays a critical role. The FDCA defines the term ‘official compendium’ as the official USP, the official NF, or any supplement to them. A drug (which includes both FDCA drugs and Public Health ...
The Drug Regimen Review
... frequently, depending on the resident’s condition and the risk for adverse consequences associated with the medications. Efforts to prevent medication-related adverse consequences and to recognize existing or emerging complications are a significant focus of clinical care in nursing homes. If there ...
... frequently, depending on the resident’s condition and the risk for adverse consequences associated with the medications. Efforts to prevent medication-related adverse consequences and to recognize existing or emerging complications are a significant focus of clinical care in nursing homes. If there ...
Omnicare Diabetes Health Management Program
... January 1997 and May 2007 that clearly define the word “polypharmacy” 24 different definitions were identified but two predominated ...
... January 1997 and May 2007 that clearly define the word “polypharmacy” 24 different definitions were identified but two predominated ...
Inflammation and Drug Idiosyncrasy—Is There a Connection?
... initial epidemiological studies suggested that rapid acetylators of INH were more susceptible to INH hepatotoxicity (reviewed by Weber et al., 1983). Studies in animals, which identified acetylhydrazine as a hepatotoxic metabolite, seemed to support a role for acetylation polymorphism as the determi ...
... initial epidemiological studies suggested that rapid acetylators of INH were more susceptible to INH hepatotoxicity (reviewed by Weber et al., 1983). Studies in animals, which identified acetylhydrazine as a hepatotoxic metabolite, seemed to support a role for acetylation polymorphism as the determi ...
Strict Liability in the Manufacture of
... interaction which occurs between the body of the patient and the drug's chemical compound. When a drug is ingested, the response of an individual patient is difficult to predict. Every effect and each adverse reaction is unique. Frequently, the response to the chemical is more dependant on the indiv ...
... interaction which occurs between the body of the patient and the drug's chemical compound. When a drug is ingested, the response of an individual patient is difficult to predict. Every effect and each adverse reaction is unique. Frequently, the response to the chemical is more dependant on the indiv ...
Another Mix-up between Choral Hydrate and
... medication was received at the community pharmacy. The nursing home resident had been receiving KCl 200 mEq daily, divided into four doses, on a long-term basis. To provide a prescription refill, the community pharmacy ordered three 500-mL bottles of KCl liquid (20 mEq/15 mL) from the warehouse. The ...
... medication was received at the community pharmacy. The nursing home resident had been receiving KCl 200 mEq daily, divided into four doses, on a long-term basis. To provide a prescription refill, the community pharmacy ordered three 500-mL bottles of KCl liquid (20 mEq/15 mL) from the warehouse. The ...
Bioidentical Hormone Therapy
... These preparations differ from custom CBHT preparations in that they are carefully controlled and regulated formulations (eg, oral, transdermal, and vaginal preparations), they are manufactured under strict standards, and their effects are subjected to scientific scrutiny.13 Numerous peer-reviewed p ...
... These preparations differ from custom CBHT preparations in that they are carefully controlled and regulated formulations (eg, oral, transdermal, and vaginal preparations), they are manufactured under strict standards, and their effects are subjected to scientific scrutiny.13 Numerous peer-reviewed p ...
Prescription rate of medications potentially contributing to lower
... ratio (SR). PSSA could be sensitive to prescribing trends, such as rapid increases in marker drug use, over time. To adjust for such temporal trends, a null-effect SR (SRnull) was calculated. SRnull is the expected SR in the absence of a causal association, given the incident medicine use and events ...
... ratio (SR). PSSA could be sensitive to prescribing trends, such as rapid increases in marker drug use, over time. To adjust for such temporal trends, a null-effect SR (SRnull) was calculated. SRnull is the expected SR in the absence of a causal association, given the incident medicine use and events ...
FORMULATION AND EVALUATION OF ORODISPERSIBLE FILM OF SILDENAFILCITRATE Research Article
... Objective: Fast dissolving drug delivery systems (FDDDSs) have acquired an important position in the market by overcoming previously encountered administration problems. FDDDSs have the unique property of rapidly disintegrating and/or dissolving and releasing the drug as soon as they come in contact ...
... Objective: Fast dissolving drug delivery systems (FDDDSs) have acquired an important position in the market by overcoming previously encountered administration problems. FDDDSs have the unique property of rapidly disintegrating and/or dissolving and releasing the drug as soon as they come in contact ...
Drug Absorption
... Pharmacokinetics of Drugs • Absorption • The drugs administration by oral route have to get absorbed across the mucous membrane of gastrointestinal tract to enter the circulation. The action of drug depends on the rate as well as the extent of absorption. • The formulation of the drug and its solub ...
... Pharmacokinetics of Drugs • Absorption • The drugs administration by oral route have to get absorbed across the mucous membrane of gastrointestinal tract to enter the circulation. The action of drug depends on the rate as well as the extent of absorption. • The formulation of the drug and its solub ...
FORMULATION AND EVALUATION OF OFLOXACIN FLOATING TABLETS USING HPMC Research Article
... polymer when it contacts with the gastric fluid, which in turn results in increase in the bulk volume and the presence of internal voids in the dry centre of the tablet (porosity). These two factors are essential for the tablet to acquire bulk density < 1, so that it remains buoyant on ...
... polymer when it contacts with the gastric fluid, which in turn results in increase in the bulk volume and the presence of internal voids in the dry centre of the tablet (porosity). These two factors are essential for the tablet to acquire bulk density < 1, so that it remains buoyant on ...