develpoment and evaluation of sustained release formulations of
... In the present study, Venlafaxine was chosen as a model drug which is a Anti-Depressant. Because of its short life (5-11hr) and its high water solubility it was chosen as a suitable candidate for sustain matrix tablet formulation. It was formulated in to matrix tablet using hydrophilic polymer such ...
... In the present study, Venlafaxine was chosen as a model drug which is a Anti-Depressant. Because of its short life (5-11hr) and its high water solubility it was chosen as a suitable candidate for sustain matrix tablet formulation. It was formulated in to matrix tablet using hydrophilic polymer such ...
FORMULATION AND EVALUATION OF LOSARTAN POTASSIUM SUSTAINED RELEASE TABLETS Research Article
... showed that powder blend have, Angle of repose range from 22 to 25, Carr’s index range from 17.38 to 18.75 and Husner’s ratio range from 1.21 to 1.23, which indicate good flow property. Hardness, Thickness and Friability was found to be in range of 8 to 10, 3.28±0.1 to 3.3± 0.2 and 0.18 to 0.271 res ...
... showed that powder blend have, Angle of repose range from 22 to 25, Carr’s index range from 17.38 to 18.75 and Husner’s ratio range from 1.21 to 1.23, which indicate good flow property. Hardness, Thickness and Friability was found to be in range of 8 to 10, 3.28±0.1 to 3.3± 0.2 and 0.18 to 0.271 res ...
Get PDF version - Bioencapsulation Research Group
... ml without inducing cytotoxicity. As future perspective, these nanoparticles appear interesting for administration also to mucosal tissue such as in the nose. In this regard, the presence of chitosan is advantageous due to its mucoadhesive properties, which may prolong retention within the nasal cav ...
... ml without inducing cytotoxicity. As future perspective, these nanoparticles appear interesting for administration also to mucosal tissue such as in the nose. In this regard, the presence of chitosan is advantageous due to its mucoadhesive properties, which may prolong retention within the nasal cav ...
Potentially hazardous drug interactions with psychotropics
... A drug interaction, defined as the modification of the action of one drug by another, can be beneficial or harmful, or it can have no significant effect. An appreciation of clinically important interactions is becoming increasingly necessary with the rising use of combinations of drugs in the manage ...
... A drug interaction, defined as the modification of the action of one drug by another, can be beneficial or harmful, or it can have no significant effect. An appreciation of clinically important interactions is becoming increasingly necessary with the rising use of combinations of drugs in the manage ...
IN VITRO RELEASE OF SODIUM DICLOFENAC FROM POLOXAMER 188 MODIFIED
... overnight and subsequently the images were recorded at 300 kV. In vitro drug release studies The in vitro drug release behaviour of pure diclofenac sodium and the optimal clay drug composite was carried out using dialysis bag method at a constant temperature bath [6]. Buffer solution of pH 1.2 (simu ...
... overnight and subsequently the images were recorded at 300 kV. In vitro drug release studies The in vitro drug release behaviour of pure diclofenac sodium and the optimal clay drug composite was carried out using dialysis bag method at a constant temperature bath [6]. Buffer solution of pH 1.2 (simu ...
OpenAs - anton pottegård
... can be regarded as a self-controlled design [16] due to the comparison of the follow-up post-exposure with that of the pre-exposure follow-up. Accordingly, this selfcontrolled design enabled us to control for confounders that are stable over time [16], e.g. unmeasured life style risk factors, which ...
... can be regarded as a self-controlled design [16] due to the comparison of the follow-up post-exposure with that of the pre-exposure follow-up. Accordingly, this selfcontrolled design enabled us to control for confounders that are stable over time [16], e.g. unmeasured life style risk factors, which ...
Judicious Use of Medications
... medications without considering removing any? Is the HCP ordering medications to manage side effects from another medication causing a cascading effect? Has the client or provider been influenced by advertisements or reports from friends about the wonders of a new medication? Does the client or nurs ...
... medications without considering removing any? Is the HCP ordering medications to manage side effects from another medication causing a cascading effect? Has the client or provider been influenced by advertisements or reports from friends about the wonders of a new medication? Does the client or nurs ...
Pharmacology
... A particular drug might be good for more than one thing, but the drug company has to choose for which use they want to seek approval. • If the drug is ultimately approved, the approval will be for that indication only. • Later, the FDA may approve the drug to treat a different indication after condu ...
... A particular drug might be good for more than one thing, but the drug company has to choose for which use they want to seek approval. • If the drug is ultimately approved, the approval will be for that indication only. • Later, the FDA may approve the drug to treat a different indication after condu ...
Effects of Solubility and Dissolution Characteristics on Oral
... ingredients had shown any significant drop in the drug content during the study period. Therefore, these excipients were used for further development work with reasonable amount of confidence that the resulting formulation will show satisfactory stability during the full scale stability studies. For ...
... ingredients had shown any significant drop in the drug content during the study period. Therefore, these excipients were used for further development work with reasonable amount of confidence that the resulting formulation will show satisfactory stability during the full scale stability studies. For ...
Chapter-2 Review of Literature
... The bioavailability of ontazolast was significantly and substantially enhanced by all of the lipid-based formulations. Abu.T.M.Serajuddin et al. (2008) investigated the solution of a poorly water-soluble drug in a liquid lipid–surfactant mixture, which served as a microemulsion preconcentrate, was c ...
... The bioavailability of ontazolast was significantly and substantially enhanced by all of the lipid-based formulations. Abu.T.M.Serajuddin et al. (2008) investigated the solution of a poorly water-soluble drug in a liquid lipid–surfactant mixture, which served as a microemulsion preconcentrate, was c ...
FULL TEXT - Journal of Pre-Clinical and Clinical Research
... of glutamate and aspartate to the synaptic cleft [4]. On the other hand, in in vitro studies on AO-294 was a less effective modulator of GABA-ergic neurotransmission [5] and inhibitor of picrotoxin-evoked discharges in hippocampal slices [3]. Since up to 30% of epileptic patients remain resistant to ...
... of glutamate and aspartate to the synaptic cleft [4]. On the other hand, in in vitro studies on AO-294 was a less effective modulator of GABA-ergic neurotransmission [5] and inhibitor of picrotoxin-evoked discharges in hippocampal slices [3]. Since up to 30% of epileptic patients remain resistant to ...
FORMULATION AND EVALUATION OF BILAYER BUCCAL TABLET OF SUMATRIPTAN SUCCINATE Original Article
... Buccal delivery of drug, as an alternative to the oral route of drug administration, is a subject of growing interest because of its numerous advantages such as good accessibility, robustness of epithelium, facile removal of dosage form in case of need, relatively low enzymatic activity, prevent dru ...
... Buccal delivery of drug, as an alternative to the oral route of drug administration, is a subject of growing interest because of its numerous advantages such as good accessibility, robustness of epithelium, facile removal of dosage form in case of need, relatively low enzymatic activity, prevent dru ...
Information on the misuse and abuse of prescription and over
... For more information on the misuse or abuse of ...
... For more information on the misuse or abuse of ...
Digitek Digoxin Recall: Tablets May Be Double The Normal Dose
... tablets that were defective, i.e., manufactured with a double-dose, as well as anything that we learn about the dates when these recalled Digitek tablets were being dispensed at pharmacies across the country. My law firm has been contacted already by several people who have had family members hospit ...
... tablets that were defective, i.e., manufactured with a double-dose, as well as anything that we learn about the dates when these recalled Digitek tablets were being dispensed at pharmacies across the country. My law firm has been contacted already by several people who have had family members hospit ...
1427967058PR Aptar Pharma Twister Sine Promod 040215LV
... Twister® is designed to be patient-friendly and easy to use, allowing patients easy access to their medication in three simple steps: insert, twist and inhale. To help improve patient compliance with the prescribed treatment, Twister® is transparent, allowing the capsule and powder to be seen in the ...
... Twister® is designed to be patient-friendly and easy to use, allowing patients easy access to their medication in three simple steps: insert, twist and inhale. To help improve patient compliance with the prescribed treatment, Twister® is transparent, allowing the capsule and powder to be seen in the ...
Product Name: Ibuprofen Oral Suspension 100mg/5mL
... 1ug/mL did not demonstrate ibuprofen in the milk of lactating mothers. Because of the limited nature of these studies, however, and the possible adverse effects of prostaglandin inhibiting drugs on newborns, this drug is not recommended for use in nursing mothers. The safety and effectiveness in ped ...
... 1ug/mL did not demonstrate ibuprofen in the milk of lactating mothers. Because of the limited nature of these studies, however, and the possible adverse effects of prostaglandin inhibiting drugs on newborns, this drug is not recommended for use in nursing mothers. The safety and effectiveness in ped ...
FORMULATION AND EVALUATION OF ATENOLOL ORODISPERSIBLE TABLETS BY PHASE TRANSITION TECHNOLOGY
... tongue”.The aim of this study is to formulate and evaluate an ODT containing antihypertensive drug Atenolol by phase transition technology and To find the formula with least time of disintegration for phase transition technology. Xylitol and Perlitol SD 200 were used as a sugar alcohols and maize st ...
... tongue”.The aim of this study is to formulate and evaluate an ODT containing antihypertensive drug Atenolol by phase transition technology and To find the formula with least time of disintegration for phase transition technology. Xylitol and Perlitol SD 200 were used as a sugar alcohols and maize st ...
Tranquilizer drug forensics - Neuroscience Consulting, Inc
... History and prevalence of the GABA A agonist drugs: Current problems of forensic concern caused by tranquilizing drug action are merely the leading edge of an historical wave. In seeking to understand the present context and future direction of this wave it helps to have an historical understanding ...
... History and prevalence of the GABA A agonist drugs: Current problems of forensic concern caused by tranquilizing drug action are merely the leading edge of an historical wave. In seeking to understand the present context and future direction of this wave it helps to have an historical understanding ...
fast dissolving tablets: preparation, characterization and evaluation
... swallowing of tablet and capsule are also occur when water is not available, in diarrhea, coughing during the common cold, allergic condition and bronchial infection2. Approximately one-third of the population (mainly pediatric and geriatric) has swallowing difficulties, resulting in poor compliance ...
... swallowing of tablet and capsule are also occur when water is not available, in diarrhea, coughing during the common cold, allergic condition and bronchial infection2. Approximately one-third of the population (mainly pediatric and geriatric) has swallowing difficulties, resulting in poor compliance ...
Formulation and In Vitro Evaluation of Minoxidil Topical Gel
... The objective of the present investigation is to develop topical gel of minoxidil using model polymers such as hydroxypropyl methylcellulose K4M (HPMC K4M) and hydroxypropyl cellulose (HPC) at different concentrations (1, 2 and 3%) individually and in combination. The drug and polymers compatibility ...
... The objective of the present investigation is to develop topical gel of minoxidil using model polymers such as hydroxypropyl methylcellulose K4M (HPMC K4M) and hydroxypropyl cellulose (HPC) at different concentrations (1, 2 and 3%) individually and in combination. The drug and polymers compatibility ...
FORMULATION AND EVALUATION OF PH TRIGGERED IN SITU OPHTHALMIC GEL... MOXIFLOXACIN HYDROCHLORIDE Research Article
... common method of drug treatment for ocular diseases and diagnosis 1. Eye drops that are conventional ophthalmic delivery systems often result in poor bioavailability and therapeutic response since the high tear fluid turnover and dynamics cause rapid precorneal elimination of the drug 2. A high freq ...
... common method of drug treatment for ocular diseases and diagnosis 1. Eye drops that are conventional ophthalmic delivery systems often result in poor bioavailability and therapeutic response since the high tear fluid turnover and dynamics cause rapid precorneal elimination of the drug 2. A high freq ...
TRANSDERMAL PATCHES: A RECENT APPROCH TO NEW DRUG DELIVERY SYSTEM
... a porous membrane covering a reservoir of medication or through body heat melting thin layers of medication embedded in the adhesive. The main disadvantage to transdermal delivery systems stems from the fact that the skin is a very effective barrier; as a result, only medications whose molecules are ...
... a porous membrane covering a reservoir of medication or through body heat melting thin layers of medication embedded in the adhesive. The main disadvantage to transdermal delivery systems stems from the fact that the skin is a very effective barrier; as a result, only medications whose molecules are ...